IT8720700A0 - Procedimento per l'estrazione di esteri di acidi grassi poliinsaturi da olii di pesce e composizioni farmaceutiche e// dietetiche contenenti detti esteri. - Google Patents
Procedimento per l'estrazione di esteri di acidi grassi poliinsaturi da olii di pesce e composizioni farmaceutiche e// dietetiche contenenti detti esteri.Info
- Publication number
- IT8720700A0 IT8720700A0 IT8720700A IT2070087A IT8720700A0 IT 8720700 A0 IT8720700 A0 IT 8720700A0 IT 8720700 A IT8720700 A IT 8720700A IT 2070087 A IT2070087 A IT 2070087A IT 8720700 A0 IT8720700 A0 IT 8720700A0
- Authority
- IT
- Italy
- Prior art keywords
- esters
- pharmaceutical
- extraction
- procedure
- fatty acids
- Prior art date
Links
- 235000005911 diet Nutrition 0.000 title 1
- 230000000378 dietary effect Effects 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 238000000605 extraction Methods 0.000 title 1
- 229940013317 fish oils Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
- C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
- C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Fats And Perfumes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20700/87A IT1205043B (it) | 1987-05-28 | 1987-05-28 | Procedimento per l'estrazione di esteri di acidi grassi poliinsaturi da olii di pesce e composizioni farmaceutiche e dietetiche contenenti detti esteri |
AT88107910T ATE110103T1 (de) | 1987-05-28 | 1988-05-18 | Verfahren zur extraktion von docosahexaensäureethylester aus fischölen und docosahexaen- und eicosapentaensäureethylester enthaltende pharmazeutische und/oder diät- zusammensetzungen. |
ES88107910T ES2056852T3 (es) | 1987-05-28 | 1988-05-18 | Un procedimiento para la extraccion del ester etilico del acido docosahexenoico a partir de aceites de pescado y composiciones farmaceuticas y/o dieteticas que contienen una mezcla de esteres etilicos del acido docosahexenoico y eicosapentenoico. |
EP88107910A EP0292846B1 (en) | 1987-05-28 | 1988-05-18 | A process for the extraction of docosahexaenoic acid ethyl ester from fish oils and pharmaceutical and/or dietetic compositions containing a mixture of docosahexaenoic and eicosapentaenoic acid ethyl esters |
DE3851092T DE3851092T2 (de) | 1987-05-28 | 1988-05-18 | Verfahren zur Extraktion von Docosahexaensäureethylester aus Fischölen und Docosahexaen- und Eicosapentaensäureethylester enthaltende pharmazeutische und/oder Diät-Zusammensetzungen. |
JP63129423A JP2721890B2 (ja) | 1987-05-28 | 1988-05-26 | 魚油からポリ不飽和脂肪酸エステルを抽出する方法 |
US07/357,650 US5130061A (en) | 1987-05-28 | 1989-05-24 | Process for the extraction of polyunsaturated fatty acid esters from fish oils |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20700/87A IT1205043B (it) | 1987-05-28 | 1987-05-28 | Procedimento per l'estrazione di esteri di acidi grassi poliinsaturi da olii di pesce e composizioni farmaceutiche e dietetiche contenenti detti esteri |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8720700A0 true IT8720700A0 (it) | 1987-05-28 |
IT1205043B IT1205043B (it) | 1989-03-10 |
Family
ID=11170757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT20700/87A IT1205043B (it) | 1987-05-28 | 1987-05-28 | Procedimento per l'estrazione di esteri di acidi grassi poliinsaturi da olii di pesce e composizioni farmaceutiche e dietetiche contenenti detti esteri |
Country Status (7)
Country | Link |
---|---|
US (1) | US5130061A (it) |
EP (1) | EP0292846B1 (it) |
JP (1) | JP2721890B2 (it) |
AT (1) | ATE110103T1 (it) |
DE (1) | DE3851092T2 (it) |
ES (1) | ES2056852T3 (it) |
IT (1) | IT1205043B (it) |
Families Citing this family (76)
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US4874629A (en) * | 1988-05-02 | 1989-10-17 | Chang Stephen S | Purification of fish oil |
GB2218984B (en) * | 1988-05-27 | 1992-09-23 | Renafield Limited | Process for preparing high-concentration mixtures of polyunsaturated fatty acids & their esters and their prophylactic or therapeutic uses |
GB8819110D0 (en) * | 1988-08-11 | 1988-09-14 | Norsk Hydro As | Antihypertensive drug & method for production |
WO1992022631A1 (en) * | 1991-06-11 | 1992-12-23 | Beku Environmental Products Ltd. | Degreaser composition comprising monounsaturated wax ester |
US5484611A (en) * | 1992-07-15 | 1996-01-16 | The Scottish Agricultural College | Method of producing a fatty acid |
JPH0717855A (ja) * | 1992-09-02 | 1995-01-20 | Maruha Corp | 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤、痴呆治療剤、または脳機能改善効果を有する機能性食品 |
ATE199481T1 (de) * | 1995-11-24 | 2001-03-15 | Loders Croklaan Bv | Zusammensetzung auf basis von fischöl |
US5917068A (en) * | 1995-12-29 | 1999-06-29 | Eastman Chemical Company | Polyunsaturated fatty acid and fatty acid ester mixtures free of sterols and phosphorus compounds |
US6063946A (en) * | 1996-01-26 | 2000-05-16 | Eastman Chemical Company | Process for the isolation of polyunsaturated fatty acids and esters thereof from complex mixtures which contain sterols and phosphorus compounds |
US5883273A (en) * | 1996-01-26 | 1999-03-16 | Abbott Laboratories | Polyunsaturated fatty acids and fatty acid esters free of sterols and phosphorus compounds |
US6200624B1 (en) | 1996-01-26 | 2001-03-13 | Abbott Laboratories | Enteral formula or nutritional supplement containing arachidonic and docosahexaenoic acids |
CN1055079C (zh) * | 1996-08-23 | 2000-08-02 | 中国科学院化学研究所 | 一种提取鱼油中不饱和脂肪酸酯的方法 |
US5955102A (en) | 1998-09-04 | 1999-09-21 | Amway Corporation | Softgel capsule containing DHA and antioxidants |
CA2260397A1 (en) | 1999-01-29 | 2000-07-29 | Atlantis Marine Inc. | Method of converting rendered triglyceride oil from marine sources into bland, stable food oil |
IT1308613B1 (it) * | 1999-02-17 | 2002-01-09 | Pharmacia & Upjohn Spa | Acidi grassi essenziali nella prevenzione di eventi cardiovascolari. |
FR2798667B1 (fr) * | 1999-09-22 | 2001-12-21 | Pharmascience Lab | Procede d'extraction des composes furaniques et alcools gras polyhydroxyles de l'avocat, composition a base de et utilisation de ces composes en therapeutique, cosmetique et alimentaire |
ITMI20010129A1 (it) | 2001-01-25 | 2002-07-25 | Pharmacia & Upjohn Spa | Acidi grassi essenziali nella terapia di insufficienza cardiaca e scompenso cardiaco |
ITMI20012384A1 (it) * | 2001-11-12 | 2003-05-12 | Quatex Nv | Uso di acidi grassi poliinsaturi per la prevenzione primaria di eventi cardiovascolari maggiori |
US6974592B2 (en) * | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
SE0202188D0 (sv) | 2002-07-11 | 2002-07-11 | Pronova Biocare As | A process for decreasing environmental pollutants in an oil or a fat, a volatile fat or oil environmental pollutants decreasing working fluid, a health supplement, and an animal feed product |
EP2295529B2 (en) | 2002-07-11 | 2022-05-18 | Basf As | Use of a volatile environmental pollutants-decreasing working fluid for decreasing the amount of pollutants in a fat for alimentary or cosmetic use |
AU2003283101B2 (en) * | 2002-11-04 | 2008-12-11 | Dsm Nutritional Products Ag | Microcapsules having multiple shells and method for the preparation thereof |
US6846942B2 (en) * | 2003-05-20 | 2005-01-25 | David Rubin | Method for preparing pure EPA and pure DHA |
DK1673423T3 (da) * | 2003-10-21 | 2009-03-30 | Dsm Ip Assets Bv | Stabilisering af polyumættede fedtsyre(PUFA)-esterkoncentrater |
ITMI20040069A1 (it) * | 2004-01-21 | 2004-04-21 | Tiberio Bruzzese | Uso di composizioni di acidi grassi n-3 ad elevata concentrazione per il trattamento di disturbi del sistema nervoso centrale |
US8034450B2 (en) * | 2005-01-21 | 2011-10-11 | Ocean Nutrition Canada Limited | Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof |
CA2556520C (en) * | 2005-01-27 | 2008-10-28 | Ocean Nutrition Canada Ltd. | Chromium-fatty acid compounds and methods of making and using thereof |
US20080139649A1 (en) * | 2005-01-27 | 2008-06-12 | Barrow Colin J | Fatty Acid-Benzenediol Derivatives and Methods of Making and Using Thereof |
US9968120B2 (en) * | 2006-05-17 | 2018-05-15 | Dsm Nutritional Products Ag | Homogenized formulations containing microcapsules and methods of making and using thereof |
EP2007224A2 (en) * | 2006-04-07 | 2008-12-31 | Ocean Nutrition Canada Limited | Emulsions and microcapsules with substances having low interfacial tension, methods of making and using thereof |
WO2007116027A1 (en) * | 2006-04-12 | 2007-10-18 | Unilever Plc | Oral composition comprising a polyunsaturated fatty acid and salicylic acid for obtaining an antiinflammatory effect in skin |
CN101466362A (zh) * | 2006-04-12 | 2009-06-24 | 荷兰联合利华有限公司 | 对皮肤具有抗老化效果的口服组合物 |
WO2008017962A2 (en) * | 2006-06-05 | 2008-02-14 | Ocean Nutrition Canada Ltd. | Microcapsules with improved shells |
JP2010515455A (ja) | 2007-01-10 | 2010-05-13 | オーシャン ニュートリッション カナダ リミテッド | 菜食マイクロカプセル |
US20080268117A1 (en) * | 2007-04-30 | 2008-10-30 | David Rubin | Method of purifying oils containing epa and dha |
MX2010000263A (es) * | 2007-06-29 | 2010-03-11 | Martek Biosciences Corp | Produccion y purificacion de esteres de acidos grasos poliinsaturados. |
US20090202672A1 (en) * | 2008-02-11 | 2009-08-13 | Monsanto Company | Aquaculture feed, products, and methods comprising beneficial fatty acids |
JP2010132631A (ja) * | 2008-11-04 | 2010-06-17 | Bizen Chemical Co Ltd | カンナビノイド受容体のインバースアゴニストおよびアンタゴニスト活性を有する組成物 |
JP5872453B2 (ja) | 2009-04-17 | 2016-03-01 | ナタク ファルマ エセ.エレ. | フィタン酸含量が低く、ω−3脂肪酸に富む組成物 |
CL2009001343A1 (es) | 2009-06-02 | 2009-07-10 | Golden Omega S A | Proceso de obtencion concentrado de esteres de epa y dha a partir de aceite marino, que comprende agregar al aceite alcali y agua a menos de 100 grados celsius, agregar solvente, separar fase de refinado, agregar acido, separar la fase no acuosa y agregar alcohol y un catalizador a menos de 150 grados celsius, desolventilizar y destilar. |
CN101766238B (zh) * | 2009-12-31 | 2012-04-25 | 山东三星玉米产业科技有限公司 | 含dha的儿童专用玉米油及其制备方法 |
EP2641597A4 (en) * | 2010-11-19 | 2014-04-30 | Nippon Suisan Kaisha Ltd | THERAPEUTIC OR PROPHYLACTIC AGENT FOR CORNEAL EPITHELIUM DISORDERS AND / OR CONNECTIVE EPITHELIUM DISORDERS |
CL2010001587A1 (es) | 2010-12-27 | 2013-01-11 | Golden Omega S A | Proceso de preparacion de un concentrado de etil esteres de acidos grasos omega-3 que comprende sobre el 80% en peso de dichos esteres en configuracion cis y sus dobles enlaces separados por una unidad metilenica. |
CA3026436A1 (en) * | 2011-02-11 | 2012-08-16 | E. I. Du Pont De Nemours And Company | Method for obtaining a lipid-containing composition from microbial biomass |
US8951514B2 (en) | 2011-02-16 | 2015-02-10 | Pivotal Therapeutics Inc. | Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels |
US8715648B2 (en) | 2011-02-16 | 2014-05-06 | Pivotal Therapeutics Inc. | Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics |
US8952000B2 (en) | 2011-02-16 | 2015-02-10 | Pivotal Therapeutics Inc. | Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events |
US9119826B2 (en) | 2011-02-16 | 2015-09-01 | Pivotal Therapeutics, Inc. | Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels |
CA2827612C (en) * | 2011-03-08 | 2018-02-27 | Cognis Ip Management Gmbh | A process for the distillation of fatty acid esters |
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CN102994236B (zh) * | 2012-12-11 | 2015-03-25 | 成都圆大生物科技有限公司 | 一种制备Omega-3大于90%的脂肪酸乙酯的方法 |
CN105263321B (zh) | 2013-03-28 | 2018-07-27 | 哥伦比亚大学纽约管理委员会 | 用omega-3甘油酯再灌注促进对用于移植的供体器官的保护 |
US9428711B2 (en) | 2013-05-07 | 2016-08-30 | Groupe Novasep | Chromatographic process for the production of highly purified polyunsaturated fatty acids |
RU2537252C1 (ru) * | 2013-06-29 | 2014-12-27 | Федеральное государственное бюджетное учреждение науки Институт биологии моря им. А.В. Жирмунского Дальневосточного отделения Российской академии наук | Способ получения докозагексаеновой кислоты |
US9328054B1 (en) | 2013-09-27 | 2016-05-03 | Travis Danner | Method of alcoholisis of fatty acids and fatty acid gyicerides |
EP3118186B1 (fr) * | 2013-12-11 | 2022-02-09 | Novasep Process | Installation chromatographique de production d acides gras polyinsatures |
US10975031B2 (en) | 2014-01-07 | 2021-04-13 | Novasep Process | Method for purifying aromatic amino acids |
CN105272844B (zh) * | 2014-06-09 | 2017-05-17 | 河北海德生物科技有限公司 | 一种提纯高纯鱼油epa乙酯和dha乙酯的方法 |
US9416091B1 (en) * | 2015-02-04 | 2016-08-16 | Sirrus, Inc. | Catalytic transesterification of ester compounds with groups reactive under transesterification conditions |
CN105384635B (zh) * | 2014-09-09 | 2018-03-09 | 浙江医药股份有限公司新昌制药厂 | 一种从鱼油中分离纯化Omega‑3脂肪酸乙酯的方法 |
BR112018006807B1 (pt) | 2015-10-05 | 2023-02-14 | Dsm Ip Assets B.V. | Processo para a separação e concentração de um óleo compreendendo ésteres de ácidos graxos poli-insaturados |
WO2017091279A1 (en) * | 2015-11-23 | 2017-06-01 | Retrotope, Inc. | Site-specific isotopic labeling of 1, 4-diene systems |
CN106753817A (zh) * | 2016-12-30 | 2017-05-31 | 山东禹王制药有限公司 | 一种高度不饱和脂肪酸鱼油的工业化生产方法 |
CN107162910B (zh) * | 2017-05-19 | 2019-12-31 | 陕西源邦生物技术有限公司 | 从鱼油中制备高纯度epa-ee的方法 |
CN111406110B (zh) * | 2017-11-17 | 2023-08-08 | 广西小藻农业科技有限公司 | 藻类多不饱和脂肪酸的制备 |
AU2018420462A1 (en) | 2018-04-25 | 2020-11-26 | Nuseed Nutritional Us Inc. | DHA enriched polyunsaturated fatty acid compositions |
PL3560342T3 (pl) | 2018-04-25 | 2021-02-22 | Nuseed Nutritional Us Inc. | Kompozycje wielonienasyconych kwasów tłuszczowych wzbogacone w dha |
CN108753451B (zh) * | 2018-05-25 | 2022-03-25 | 江南大学 | 一种注射级中/长链结构甘油三酯的纯化方法及其产品 |
EP3586640A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
EP3586642A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Ala enriched polyunsaturated fatty acid compositions |
EP3586643A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
EP3586641A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
CN109369389A (zh) * | 2018-12-20 | 2019-02-22 | 燕园泽龙(涿鹿)生物科技有限公司 | 高纯度α-亚麻酸乙酯的制备工艺 |
CA3172351A1 (en) | 2020-02-21 | 2021-08-26 | Retrotope, Inc. | Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof |
CN113004977A (zh) * | 2021-02-25 | 2021-06-22 | 华侨大学 | 高纯度多不饱和鱼油的制备方法以及鱿鱼油加工方法 |
CN115350493A (zh) * | 2022-09-15 | 2022-11-18 | 江苏海莱康生物科技有限公司 | 一种分离提纯鱼油中的二十碳五烯酸乙酯的方法及精馏装置 |
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-
1987
- 1987-05-28 IT IT20700/87A patent/IT1205043B/it active
-
1988
- 1988-05-18 ES ES88107910T patent/ES2056852T3/es not_active Expired - Lifetime
- 1988-05-18 DE DE3851092T patent/DE3851092T2/de not_active Expired - Lifetime
- 1988-05-18 AT AT88107910T patent/ATE110103T1/de not_active IP Right Cessation
- 1988-05-18 EP EP88107910A patent/EP0292846B1/en not_active Expired - Lifetime
- 1988-05-26 JP JP63129423A patent/JP2721890B2/ja not_active Expired - Lifetime
-
1989
- 1989-05-24 US US07/357,650 patent/US5130061A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE110103T1 (de) | 1994-09-15 |
DE3851092T2 (de) | 1994-12-01 |
EP0292846A2 (en) | 1988-11-30 |
US5130061A (en) | 1992-07-14 |
DE3851092D1 (de) | 1994-09-22 |
EP0292846B1 (en) | 1994-08-17 |
JP2721890B2 (ja) | 1998-03-04 |
ES2056852T3 (es) | 1994-10-16 |
IT1205043B (it) | 1989-03-10 |
JPS6470439A (en) | 1989-03-15 |
EP0292846A3 (en) | 1990-03-21 |
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