IT8422334A0 - Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione. - Google Patents

Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione.

Info

Publication number
IT8422334A0
IT8422334A0 IT8422334A IT2233484A IT8422334A0 IT 8422334 A0 IT8422334 A0 IT 8422334A0 IT 8422334 A IT8422334 A IT 8422334A IT 2233484 A IT2233484 A IT 2233484A IT 8422334 A0 IT8422334 A0 IT 8422334A0
Authority
IT
Italy
Prior art keywords
preparation
pharmacologically active
piperazine derivatives
active piperazine
derivatives
Prior art date
Application number
IT8422334A
Other languages
English (en)
Other versions
IT1176613B (it
Inventor
Francesco Botre
Roberto Signorini
Original Assignee
Ravizza Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ravizza Spa filed Critical Ravizza Spa
Priority to IT22334/84A priority Critical patent/IT1176613B/it
Publication of IT8422334A0 publication Critical patent/IT8422334A0/it
Priority to EP85108942A priority patent/EP0171636A1/en
Priority to US06/756,257 priority patent/US4940793A/en
Priority to JP60177809A priority patent/JPS6156167A/ja
Application granted granted Critical
Publication of IT1176613B publication Critical patent/IT1176613B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT22334/84A 1984-08-14 1984-08-14 Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione IT1176613B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT22334/84A IT1176613B (it) 1984-08-14 1984-08-14 Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione
EP85108942A EP0171636A1 (en) 1984-08-14 1985-07-17 Pharmacologically active piperazino derivatives and the process for their preparation
US06/756,257 US4940793A (en) 1984-08-14 1985-07-18 Pharmacologically active piperazino derivatives
JP60177809A JPS6156167A (ja) 1984-08-14 1985-08-14 薬学的に活性なピペラジノ誘導体及びその製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22334/84A IT1176613B (it) 1984-08-14 1984-08-14 Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione

Publications (2)

Publication Number Publication Date
IT8422334A0 true IT8422334A0 (it) 1984-08-14
IT1176613B IT1176613B (it) 1987-08-18

Family

ID=11194823

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22334/84A IT1176613B (it) 1984-08-14 1984-08-14 Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione

Country Status (4)

Country Link
US (1) US4940793A (it)
EP (1) EP0171636A1 (it)
JP (1) JPS6156167A (it)
IT (1) IT1176613B (it)

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US5756742A (en) * 1995-12-22 1998-05-26 Henkel Corporation Polymerizable compounds
US5885995A (en) * 1996-04-03 1999-03-23 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
WO1997036592A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5972942A (en) * 1997-03-27 1999-10-26 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
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US7183410B2 (en) * 2001-08-02 2007-02-27 Bidachem S.P.A. Stable polymorph of flibanserin
US20030060475A1 (en) * 2001-08-10 2003-03-27 Boehringer Ingelheim Pharma Kg Method of using flibanserin for neuroprotection
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
US7046924B2 (en) 2002-11-25 2006-05-16 Eastman Kodak Company Method and computer program product for determining an area of importance in an image using eye monitoring information
US7327890B2 (en) 2002-12-20 2008-02-05 Eastman Kodak Company Imaging method and system for determining an area of importance in an archival image
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MX2007006429A (es) 2004-12-09 2007-07-19 Hoffmann La Roche Derivados de fenil-piperazin-metanona.
JP4709849B2 (ja) 2004-12-15 2011-06-29 エフ．ホフマン−ラ ロシュ アーゲー アルツハイマー病治療のためのグリシントランスポーターｉ（ｇｌｙｔ−１）インヒビターとしての二環式及び三環式置換フェニルメタノン類
US7485637B2 (en) 2005-01-04 2009-02-03 Hoffmann-La Roche Inc. Benzoyl-tetrahydropiperidine derivatives
KR100895752B1 (ko) 2005-01-07 2009-04-30 에프. 호프만-라 로슈 아게 신경 질환 및 신경정신 질환을 치료하기 위한 글라이신수송자 1(ｇｌｙｔ-1) 저해제로서의[4-(헤테로아릴)피페라진-1-일]-(2,5-치환-페닐)메탄온유도체
CN101141959B (zh) 2005-01-18 2010-12-15 弗·哈夫曼-拉罗切有限公司 作为甘氨酸转运体1(GlyT-1)抑制剂用于治疗神经学和神经精神病学障碍的2,5-二取代的苯甲酮衍生物
CA2595605A1 (en) 2005-01-26 2006-08-03 F. Hoffmann-La Roche Ag Phenyl methanone derivatives and their use as glycine transporter 1 inhibitors
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EP1858515A2 (en) * 2005-03-04 2007-11-28 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders
CA2599721A1 (en) * 2005-03-04 2006-09-14 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment and/or prevention of depression
CA2608249A1 (en) * 2005-05-06 2006-11-16 Boehringer Ingelheim International Gmbh Method for the treatment of drug abuse with flibanserin
CA2608713A1 (en) * 2005-05-19 2006-11-23 Boehringer Ingelheim International Gmbh Method for the treatment of sexual dysfunctions due to medical conditions
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US8222424B2 (en) 2008-03-24 2012-07-17 Novartis Ag Arylsulfonamide-based matrix metalloprotease inhibitors
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UA123362C2 (uk) 2015-09-04 2021-03-24 Ф. Хоффманн-Ля Рош Аг Феноксиметильні похідні
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Also Published As

Publication number Publication date
JPS6156167A (ja) 1986-03-20
US4940793A (en) 1990-07-10
EP0171636A1 (en) 1986-02-19
IT1176613B (it) 1987-08-18

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