IT8149179A0 - N-(1-allil-2-pirrolidinil-metil)-2metossi-4-ammino-5-metil-solfammoilbenzammide procedimento per produrla e sua applicazione come medicamento - Google Patents
N-(1-allil-2-pirrolidinil-metil)-2metossi-4-ammino-5-metil-solfammoilbenzammide procedimento per produrla e sua applicazione come medicamentoInfo
- Publication number
- IT8149179A0 IT8149179A0 IT8149179A IT4917981A IT8149179A0 IT 8149179 A0 IT8149179 A0 IT 8149179A0 IT 8149179 A IT8149179 A IT 8149179A IT 4917981 A IT4917981 A IT 4917981A IT 8149179 A0 IT8149179 A0 IT 8149179A0
- Authority
- IT
- Italy
- Prior art keywords
- methyl
- sulfammoylbenzaamide
- 2methoxy
- pyrrolidinyl
- allyl
- Prior art date
Links
- 229940126601 medicinal product Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8018635A FR2489327B1 (fr) | 1980-08-28 | 1980-08-28 | N (1 allyl 2 pyrrolidinyl methyl) 2 methoxy 4 amino 5 methylsulfa moyl benzamide, son procede de preparation et son application comme medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8149179A0 true IT8149179A0 (it) | 1981-08-26 |
IT1171490B IT1171490B (it) | 1987-06-10 |
Family
ID=9245444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT49179/81A IT1171490B (it) | 1980-08-28 | 1981-08-26 | N-(1-allil-2-pirrolidinil-metil)-2-metossi-4-ammino-5-metil-solfammoil benzammide procedimento per produrla e sua applicazione come medicamento |
Country Status (41)
Country | Link |
---|---|
US (2) | US4405636A (it) |
EP (1) | EP0047207B1 (it) |
JP (1) | JPS5775969A (it) |
KR (1) | KR840002063B1 (it) |
AR (1) | AR226737A1 (it) |
AT (1) | ATE11911T1 (it) |
AU (1) | AU549396B2 (it) |
BE (1) | BE890085A (it) |
BG (1) | BG36931A3 (it) |
CA (1) | CA1168250A (it) |
CH (1) | CH648299A5 (it) |
CS (1) | CS223895B2 (it) |
DD (1) | DD202011A5 (it) |
DE (2) | DE3133768A1 (it) |
DK (1) | DK157845C (it) |
EG (1) | EG15376A (it) |
ES (1) | ES8301466A1 (it) |
FI (1) | FI73207C (it) |
FR (1) | FR2489327B1 (it) |
GB (1) | GB2083033B (it) |
GR (1) | GR74560B (it) |
HK (1) | HK55989A (it) |
HU (1) | HU183555B (it) |
IE (1) | IE51357B1 (it) |
IL (1) | IL63217A (it) |
IN (1) | IN155495B (it) |
IS (1) | IS1213B6 (it) |
IT (1) | IT1171490B (it) |
JO (1) | JO1120B1 (it) |
LU (1) | LU83583A1 (it) |
MA (1) | MA19218A1 (it) |
MX (1) | MX6707E (it) |
NO (1) | NO155097C (it) |
OA (1) | OA06877A (it) |
PH (1) | PH19211A (it) |
PL (1) | PL135397B1 (it) |
PT (1) | PT73509B (it) |
SU (1) | SU1148559A3 (it) |
YU (1) | YU42581B (it) |
ZA (1) | ZA814575B (it) |
ZW (1) | ZW17581A1 (it) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8317597D0 (en) * | 1983-06-29 | 1983-08-03 | Beecham Group Plc | Pharmaceutical compounds |
FR2550447B1 (fr) * | 1983-08-10 | 1986-01-17 | Ile De France | Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire |
FR2584605B1 (fr) * | 1985-07-15 | 1988-06-17 | Ile De France | Application du n-(1-allyl-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide dans le traitement de la maladie de parkinson |
US7544676B2 (en) * | 2005-11-10 | 2009-06-09 | Adolor Corporation | Sulfamoyl benzamides and methods of their use |
CN101628886B (zh) * | 2009-08-25 | 2012-12-12 | 北京紫萌同达科技有限公司 | 一种2-甲氧基-4-氨基-5-乙砜基苯甲酸的合成方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1525M (fr) * | 1961-07-25 | 1962-11-16 | Ile De France | Médicaments antiémétiques nouveaux. |
US3342826A (en) * | 1964-01-13 | 1967-09-19 | Ile De France | Heterocyclic aminoalkyl benzamides |
FR5916M (it) * | 1966-01-21 | 1968-05-06 | ||
US3766178A (en) * | 1967-04-03 | 1973-10-16 | Ile De France | Substituted 2-arylalkyloxy benzamides |
GB1364231A (en) | 1968-12-23 | 1974-08-21 | Robins Co Inc A H | N-/1-substituted-3-pyrrolidinyl/benzamides and thiobenzamides |
US3862139A (en) * | 1972-06-23 | 1975-01-21 | Delmar Chem | Heterocyclic benzamide compounds |
FR2244760B1 (it) * | 1973-09-25 | 1980-06-27 | Ile De France | |
CH605793A5 (it) * | 1974-03-05 | 1978-10-13 | Ile De France | |
FR2294698A1 (fr) * | 1974-12-18 | 1976-07-16 | Synthelabo | Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment |
US4197243A (en) * | 1975-04-02 | 1980-04-08 | Yamanouchi Pharmaceutical Co., Ltd. | N-1-Benzyl-3-pyrrolidinyl-4-dimethylamino benzamide derivatives |
US4186135A (en) * | 1976-08-04 | 1980-01-29 | Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France | Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation |
FR2438650A1 (fr) * | 1978-10-11 | 1980-05-09 | Ile De France | N-(1-methyl 2-pyrrolidinyl methyl) 2,3-dimethoxy 5-methylsulfamoyl benzamide et ses derives, leurs methodes de preparation et leur application dans le traitement des troubles du bas appareil urinaire |
US4210660A (en) * | 1978-12-20 | 1980-07-01 | Yamanouchi Pharmaceutical Co., Ltd. | Benzamide derivatives |
JPS55130957A (en) * | 1979-03-30 | 1980-10-11 | Kyowa Hakko Kogyo Co Ltd | Production of benzamide derivative |
-
1980
- 1980-08-28 FR FR8018635A patent/FR2489327B1/fr not_active Expired
-
1981
- 1981-06-29 IE IE1449/81A patent/IE51357B1/en not_active IP Right Cessation
- 1981-07-01 IL IL63217A patent/IL63217A/xx not_active IP Right Cessation
- 1981-07-07 ZA ZA814575A patent/ZA814575B/xx unknown
- 1981-07-07 IS IS2654A patent/IS1213B6/is unknown
- 1981-07-09 CH CH4520/81A patent/CH648299A5/fr not_active IP Right Cessation
- 1981-07-09 ES ES503805A patent/ES8301466A1/es not_active Expired
- 1981-07-13 IN IN783/CAL/81A patent/IN155495B/en unknown
- 1981-07-14 BG BG8152939A patent/BG36931A3/xx unknown
- 1981-07-16 MA MA19418A patent/MA19218A1/fr unknown
- 1981-07-23 GR GR65602A patent/GR74560B/el unknown
- 1981-07-24 ZW ZW175/81A patent/ZW17581A1/xx unknown
- 1981-07-28 EG EG434/81A patent/EG15376A/xx active
- 1981-07-28 PH PH197873A patent/PH19211A/en unknown
- 1981-07-31 KR KR1019810002789A patent/KR840002063B1/ko active
- 1981-08-07 SU SU813318201A patent/SU1148559A3/ru active
- 1981-08-10 OA OA57469A patent/OA06877A/xx unknown
- 1981-08-12 PT PT73509A patent/PT73509B/pt not_active IP Right Cessation
- 1981-08-13 FI FI812506A patent/FI73207C/fi not_active IP Right Cessation
- 1981-08-14 AR AR286438A patent/AR226737A1/es active
- 1981-08-14 CA CA000383949A patent/CA1168250A/fr not_active Expired
- 1981-08-18 PL PL1981232686A patent/PL135397B1/pl unknown
- 1981-08-19 YU YU2010/81A patent/YU42581B/xx unknown
- 1981-08-24 GB GB8125796A patent/GB2083033B/en not_active Expired
- 1981-08-24 CS CS816314A patent/CS223895B2/cs unknown
- 1981-08-25 DD DD81232783A patent/DD202011A5/de unknown
- 1981-08-25 US US06/296,164 patent/US4405636A/en not_active Expired - Fee Related
- 1981-08-25 JO JO19811120A patent/JO1120B1/en active
- 1981-08-26 EP EP81401340A patent/EP0047207B1/fr not_active Expired
- 1981-08-26 IT IT49179/81A patent/IT1171490B/it active
- 1981-08-26 LU LU83583A patent/LU83583A1/fr unknown
- 1981-08-26 BE BE1/10298A patent/BE890085A/fr not_active IP Right Cessation
- 1981-08-26 AU AU74642/81A patent/AU549396B2/en not_active Ceased
- 1981-08-26 DE DE19813133768 patent/DE3133768A1/de not_active Withdrawn
- 1981-08-26 DE DE8181401340T patent/DE3169052D1/de not_active Expired
- 1981-08-26 AT AT81401340T patent/ATE11911T1/de not_active IP Right Cessation
- 1981-08-28 DK DK383081A patent/DK157845C/da not_active IP Right Cessation
- 1981-08-28 NO NO812937A patent/NO155097C/no unknown
- 1981-08-28 JP JP56136046A patent/JPS5775969A/ja active Granted
- 1981-08-28 MX MX819635U patent/MX6707E/es unknown
- 1981-08-28 HU HU812492A patent/HU183555B/hu not_active IP Right Cessation
-
1983
- 1983-02-15 US US06/466,573 patent/US4550179A/en not_active Expired - Fee Related
-
1989
- 1989-07-13 HK HK559/89A patent/HK55989A/xx unknown
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