IL63217A - N-(1-allyl-2-pyrrolidinyl-methyl)2-methoxy-4-amino-5-methylsulfamoyl benzamide,its preparation and pharmaceutical compositions containing it - Google Patents

N-(1-allyl-2-pyrrolidinyl-methyl)2-methoxy-4-amino-5-methylsulfamoyl benzamide,its preparation and pharmaceutical compositions containing it

Info

Publication number
IL63217A
IL63217A IL63217A IL6321781A IL63217A IL 63217 A IL63217 A IL 63217A IL 63217 A IL63217 A IL 63217A IL 6321781 A IL6321781 A IL 6321781A IL 63217 A IL63217 A IL 63217A
Authority
IL
Israel
Prior art keywords
pyrrolidinyl
allyl
methoxy
amino
methyl
Prior art date
Application number
IL63217A
Other languages
English (en)
Other versions
IL63217A0 (en
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Publication of IL63217A0 publication Critical patent/IL63217A0/xx
Publication of IL63217A publication Critical patent/IL63217A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
IL63217A 1980-08-28 1981-07-01 N-(1-allyl-2-pyrrolidinyl-methyl)2-methoxy-4-amino-5-methylsulfamoyl benzamide,its preparation and pharmaceutical compositions containing it IL63217A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8018635A FR2489327B1 (fr) 1980-08-28 1980-08-28 N (1 allyl 2 pyrrolidinyl methyl) 2 methoxy 4 amino 5 methylsulfa moyl benzamide, son procede de preparation et son application comme medicament

Publications (2)

Publication Number Publication Date
IL63217A0 IL63217A0 (en) 1981-10-30
IL63217A true IL63217A (en) 1985-03-31

Family

ID=9245444

Family Applications (1)

Application Number Title Priority Date Filing Date
IL63217A IL63217A (en) 1980-08-28 1981-07-01 N-(1-allyl-2-pyrrolidinyl-methyl)2-methoxy-4-amino-5-methylsulfamoyl benzamide,its preparation and pharmaceutical compositions containing it

Country Status (41)

Country Link
US (2) US4405636A (xx)
EP (1) EP0047207B1 (xx)
JP (1) JPS5775969A (xx)
KR (1) KR840002063B1 (xx)
AR (1) AR226737A1 (xx)
AT (1) ATE11911T1 (xx)
AU (1) AU549396B2 (xx)
BE (1) BE890085A (xx)
BG (1) BG36931A3 (xx)
CA (1) CA1168250A (xx)
CH (1) CH648299A5 (xx)
CS (1) CS223895B2 (xx)
DD (1) DD202011A5 (xx)
DE (2) DE3133768A1 (xx)
DK (1) DK157845C (xx)
EG (1) EG15376A (xx)
ES (1) ES8301466A1 (xx)
FI (1) FI73207C (xx)
FR (1) FR2489327B1 (xx)
GB (1) GB2083033B (xx)
GR (1) GR74560B (xx)
HK (1) HK55989A (xx)
HU (1) HU183555B (xx)
IE (1) IE51357B1 (xx)
IL (1) IL63217A (xx)
IN (1) IN155495B (xx)
IS (1) IS1213B6 (xx)
IT (1) IT1171490B (xx)
JO (1) JO1120B1 (xx)
LU (1) LU83583A1 (xx)
MA (1) MA19218A1 (xx)
MX (1) MX6707E (xx)
NO (1) NO155097C (xx)
OA (1) OA06877A (xx)
PH (1) PH19211A (xx)
PL (1) PL135397B1 (xx)
PT (1) PT73509B (xx)
SU (1) SU1148559A3 (xx)
YU (1) YU42581B (xx)
ZA (1) ZA814575B (xx)
ZW (1) ZW17581A1 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8317597D0 (en) * 1983-06-29 1983-08-03 Beecham Group Plc Pharmaceutical compounds
FR2550447B1 (fr) * 1983-08-10 1986-01-17 Ile De France Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire
FR2584605B1 (fr) * 1985-07-15 1988-06-17 Ile De France Application du n-(1-allyl-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide dans le traitement de la maladie de parkinson
US7544676B2 (en) * 2005-11-10 2009-06-09 Adolor Corporation Sulfamoyl benzamides and methods of their use
CN101628886B (zh) * 2009-08-25 2012-12-12 北京紫萌同达科技有限公司 一种2-甲氧基-4-氨基-5-乙砜基苯甲酸的合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1525M (fr) * 1961-07-25 1962-11-16 Ile De France Médicaments antiémétiques nouveaux.
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR5916M (xx) * 1966-01-21 1968-05-06
US3766178A (en) * 1967-04-03 1973-10-16 Ile De France Substituted 2-arylalkyloxy benzamides
GB1364231A (en) 1968-12-23 1974-08-21 Robins Co Inc A H N-/1-substituted-3-pyrrolidinyl/benzamides and thiobenzamides
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
FR2244760B1 (xx) * 1973-09-25 1980-06-27 Ile De France
CH605793A5 (xx) * 1974-03-05 1978-10-13 Ile De France
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
US4197243A (en) * 1975-04-02 1980-04-08 Yamanouchi Pharmaceutical Co., Ltd. N-1-Benzyl-3-pyrrolidinyl-4-dimethylamino benzamide derivatives
US4186135A (en) * 1976-08-04 1980-01-29 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation
FR2438650A1 (fr) * 1978-10-11 1980-05-09 Ile De France N-(1-methyl 2-pyrrolidinyl methyl) 2,3-dimethoxy 5-methylsulfamoyl benzamide et ses derives, leurs methodes de preparation et leur application dans le traitement des troubles du bas appareil urinaire
US4210660A (en) * 1978-12-20 1980-07-01 Yamanouchi Pharmaceutical Co., Ltd. Benzamide derivatives
JPS55130957A (en) * 1979-03-30 1980-10-11 Kyowa Hakko Kogyo Co Ltd Production of benzamide derivative

Also Published As

Publication number Publication date
GR74560B (xx) 1984-06-29
BG36931A3 (en) 1985-02-15
AU549396B2 (en) 1986-01-23
US4550179A (en) 1985-10-29
FI73207B (fi) 1987-05-29
DK383081A (da) 1982-03-01
YU201081A (en) 1983-10-31
IE811449L (en) 1982-02-28
LU83583A1 (fr) 1981-12-01
NO155097B (no) 1986-11-03
NO155097C (no) 1987-02-11
FI73207C (fi) 1987-09-10
DK157845C (da) 1990-07-23
PH19211A (en) 1986-02-04
IS2654A7 (is) 1981-09-11
JPH0233027B2 (xx) 1990-07-25
HK55989A (en) 1989-07-21
CS223895B2 (en) 1983-11-25
KR830006201A (ko) 1983-09-20
JPS5775969A (en) 1982-05-12
DE3169052D1 (en) 1985-03-28
KR840002063B1 (ko) 1984-11-09
IT8149179A0 (it) 1981-08-26
MX6707E (es) 1985-10-23
ES503805A0 (es) 1982-12-01
SU1148559A3 (ru) 1985-03-30
AR226737A1 (es) 1982-08-13
OA06877A (fr) 1983-04-30
PT73509A (fr) 1981-09-01
EP0047207A1 (fr) 1982-03-10
GB2083033A (en) 1982-03-17
IT1171490B (it) 1987-06-10
PT73509B (fr) 1982-10-28
US4405636A (en) 1983-09-20
PL232686A1 (xx) 1982-03-01
EG15376A (en) 1986-12-30
EP0047207B1 (fr) 1985-02-20
DK157845B (da) 1990-02-26
FR2489327A1 (fr) 1982-03-05
FR2489327B1 (fr) 1984-05-18
ES8301466A1 (es) 1982-12-01
NO812937L (no) 1982-03-01
CA1168250A (fr) 1984-05-29
PL135397B1 (en) 1985-10-31
ZW17581A1 (en) 1981-10-21
IS1213B6 (is) 1986-04-02
HU183555B (en) 1984-05-28
IE51357B1 (en) 1986-12-10
FI812506L (fi) 1982-03-01
YU42581B (en) 1988-10-31
DD202011A5 (de) 1983-08-24
IN155495B (xx) 1985-02-09
ZA814575B (en) 1982-07-28
CH648299A5 (fr) 1985-03-15
BE890085A (fr) 1982-02-26
JO1120B1 (en) 1982-07-10
AU7464281A (en) 1982-03-04
GB2083033B (en) 1984-02-01
DE3133768A1 (de) 1982-06-16
ATE11911T1 (de) 1985-03-15
MA19218A1 (fr) 1982-04-01
IL63217A0 (en) 1981-10-30

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