IT1256238B - Derivati del benzofuranilimidazolo, un procedimento per la loro prepazione e composizioni terapeutiche che li contengono - Google Patents
Derivati del benzofuranilimidazolo, un procedimento per la loro prepazione e composizioni terapeutiche che li contengonoInfo
- Publication number
- IT1256238B IT1256238B ITMI922954A ITMI922954A IT1256238B IT 1256238 B IT1256238 B IT 1256238B IT MI922954 A ITMI922954 A IT MI922954A IT MI922954 A ITMI922954 A IT MI922954A IT 1256238 B IT1256238 B IT 1256238B
- Authority
- IT
- Italy
- Prior art keywords
- derivatives
- benzofuranylimidazol
- prepation
- procedure
- contain
- Prior art date
Links
- VBFQIUOSXHUWCT-UHFFFAOYSA-N 2-(1-benzofuran-2-yl)-1h-imidazole Chemical class C1=CNC(C=2OC3=CC=CC=C3C=2)=N1 VBFQIUOSXHUWCT-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente invenzione riguarda derivati del benzofuranilimidazolo di formula generale (1) (FORMULA) in cui R1 e R2 rappresentano diversi radicali, riguarda un procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919127430A GB9127430D0 (en) | 1991-12-27 | 1991-12-27 | Benzofuranylimidazole derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI922954A0 ITMI922954A0 (it) | 1992-12-23 |
| ITMI922954A1 ITMI922954A1 (it) | 1994-06-23 |
| IT1256238B true IT1256238B (it) | 1995-11-29 |
Family
ID=10706855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI922954A IT1256238B (it) | 1991-12-27 | 1992-12-23 | Derivati del benzofuranilimidazolo, un procedimento per la loro prepazione e composizioni terapeutiche che li contengono |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US5310930A (it) |
| JP (1) | JPH05271223A (it) |
| AT (1) | AT402071B (it) |
| AU (1) | AU652877B2 (it) |
| BE (1) | BE1006226A3 (it) |
| CA (1) | CA2086137C (it) |
| CH (1) | CH685344A5 (it) |
| DE (1) | DE4244342C2 (it) |
| DK (1) | DK155692A (it) |
| DZ (1) | DZ1655A1 (it) |
| ES (1) | ES2049186B1 (it) |
| FI (1) | FI111365B (it) |
| FR (2) | FR2685698B1 (it) |
| GB (2) | GB9127430D0 (it) |
| GR (1) | GR1001566B (it) |
| HK (1) | HK27096A (it) |
| HU (1) | HUT67269A (it) |
| IE (1) | IE73489B1 (it) |
| IN (1) | IN180496B (it) |
| IT (1) | IT1256238B (it) |
| LU (1) | LU88204A1 (it) |
| MA (1) | MA22752A1 (it) |
| MY (1) | MY109729A (it) |
| NL (1) | NL9202238A (it) |
| NO (1) | NO300841B1 (it) |
| NZ (1) | NZ245500A (it) |
| OA (1) | OA09903A (it) |
| PL (3) | PL170205B1 (it) |
| PT (1) | PT101158B (it) |
| RU (1) | RU2068416C1 (it) |
| SE (1) | SE503224C2 (it) |
| TN (1) | TNSN92118A1 (it) |
| TW (1) | TW226997B (it) |
| ZA (1) | ZA929736B (it) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9127050D0 (en) * | 1991-12-20 | 1992-02-19 | Orion Yhtymae Oy | Substituted imidazole derivatives and their preparation and use |
| PT924209E (pt) * | 1997-12-19 | 2003-08-29 | Lilly Co Eli | Compostos de imidazolina hipoglicemicos |
| EP1266897A3 (en) * | 1997-12-19 | 2003-12-03 | Eli Lilly And Company | Hypoglycemic imidazoline compounds |
| GB2351082A (en) * | 1999-06-18 | 2000-12-20 | Lilly Forschung Gmbh | Synthesis of Cyclic Substituted Amidines |
| CN1326852C (zh) * | 2003-03-07 | 2007-07-18 | 兴和株式会社 | 苯并呋喃衍生物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH593967A5 (en) * | 1971-11-09 | 1977-12-30 | Ciba Geigy Ag | Optical brighteners for organic materials - consist of quaternised benzofuranyl or naphthofuranyl benzimidazole cpds. |
| US3927023A (en) * | 1974-05-24 | 1975-12-16 | Warner Lambert Co | Imidazolyl benzofurans |
| NZ201219A (en) * | 1981-07-28 | 1984-10-19 | Reckitt & Colmann Prod Ltd | Dihydrobenzofuranyl-2-imidazolines and pharmaceutical compositions |
| GB2122987B (en) * | 1982-06-01 | 1985-09-25 | Zyma Sa | (+)-cyanidan-3-ol derivatives and pharmaceutical preparations thereof |
| ES523609A0 (es) * | 1982-07-05 | 1985-03-01 | Erba Farmitalia | Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos. |
| GB2167408B (en) * | 1984-11-23 | 1988-05-25 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
| GB8720693D0 (en) * | 1987-09-03 | 1987-10-07 | Glaxo Group Ltd | Chemical compounds |
| GB8805628D0 (en) * | 1988-03-09 | 1988-04-07 | Erba Farmitalia | Hypolipidaemic imidazol-2-yl-derivatives of bicyclic compounds & process for their preparation |
-
1991
- 1991-12-27 GB GB919127430A patent/GB9127430D0/en active Pending
-
1992
- 1992-12-11 IN IN1187DE1992 patent/IN180496B/en unknown
- 1992-12-15 ZA ZA929736A patent/ZA929736B/xx unknown
- 1992-12-17 NZ NZ245500A patent/NZ245500A/xx unknown
- 1992-12-18 MY MYPI92002345A patent/MY109729A/en unknown
- 1992-12-18 FI FI925755A patent/FI111365B/fi active
- 1992-12-18 CH CH3891/92A patent/CH685344A5/fr not_active IP Right Cessation
- 1992-12-18 GR GR920100564A patent/GR1001566B/el not_active IP Right Cessation
- 1992-12-18 SE SE9203824A patent/SE503224C2/sv not_active IP Right Cessation
- 1992-12-21 AT AT0252892A patent/AT402071B/de not_active IP Right Cessation
- 1992-12-22 LU LU88204A patent/LU88204A1/fr unknown
- 1992-12-22 PL PL92297109A patent/PL170205B1/pl unknown
- 1992-12-22 FR FR9215445A patent/FR2685698B1/fr not_active Expired - Fee Related
- 1992-12-22 BE BE9201126A patent/BE1006226A3/fr not_active IP Right Cessation
- 1992-12-22 PL PL92312899A patent/PL170409B1/pl unknown
- 1992-12-22 PL PL92312900A patent/PL170404B1/pl unknown
- 1992-12-22 FR FR9215446A patent/FR2685637B1/fr not_active Expired - Fee Related
- 1992-12-23 HU HU9204120A patent/HUT67269A/hu unknown
- 1992-12-23 PT PT101158A patent/PT101158B/pt not_active IP Right Cessation
- 1992-12-23 NL NL9202238A patent/NL9202238A/nl not_active Application Discontinuation
- 1992-12-23 CA CA002086137A patent/CA2086137C/en not_active Expired - Fee Related
- 1992-12-23 US US07/995,790 patent/US5310930A/en not_active Expired - Lifetime
- 1992-12-23 NO NO925007A patent/NO300841B1/no unknown
- 1992-12-23 DK DK155692A patent/DK155692A/da not_active Application Discontinuation
- 1992-12-23 IT ITMI922954A patent/IT1256238B/it active IP Right Grant
- 1992-12-23 IE IE922945A patent/IE73489B1/en not_active IP Right Cessation
- 1992-12-24 AU AU30496/92A patent/AU652877B2/en not_active Ceased
- 1992-12-24 GB GB9226997A patent/GB2262739B/en not_active Expired - Fee Related
- 1992-12-24 ES ES09202615A patent/ES2049186B1/es not_active Expired - Fee Related
- 1992-12-24 OA OA60323A patent/OA09903A/fr unknown
- 1992-12-25 MA MA23044A patent/MA22752A1/fr unknown
- 1992-12-25 RU RU9292016209A patent/RU2068416C1/ru active
- 1992-12-25 JP JP4347195A patent/JPH05271223A/ja active Pending
- 1992-12-27 DZ DZ920169A patent/DZ1655A1/fr active
- 1992-12-27 TN TNTNSN92118A patent/TNSN92118A1/fr unknown
- 1992-12-28 DE DE4244342A patent/DE4244342C2/de not_active Expired - Fee Related
- 1992-12-29 TW TW081110441A patent/TW226997B/zh active
-
1993
- 1993-12-02 US US08/161,226 patent/US5354769A/en not_active Expired - Lifetime
-
1996
- 1996-02-15 HK HK27096A patent/HK27096A/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2145774T3 (es) | Derivados de adenosina que tienen actividad agonista en a2. | |
| ES2084944T3 (es) | Amidas terapeuticas. | |
| ES2095432T3 (es) | Derivados de 2,4-tiazolidin-diona, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| IL123002A0 (en) | 1-Phenyl-2- phenylacetoxy- ethanone derivatives | |
| ES2136037B1 (es) | Inhibidores de sulfamida-metaloproteasa | |
| ES2104708T3 (es) | Compuestos heterociclicos terapeuticos. | |
| FI931031A0 (fi) | Mometasonfuroatmonohydrat, foerfarande foer dess framstaellning och farmaceutiska sammansaettningar | |
| FR2644786B1 (fr) | Nouveaux derives fluoro-4 benzoiques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent | |
| MX9207494A (es) | 4(5)-amino-1,8-naftiridinas substituidas, procedimiento para su preparacion y composiciones farmaceuticas que las contienen. | |
| FR2679906B1 (fr) | Nouvelles (isoquinolein-5 yl) sulfonamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. | |
| IT1265101B1 (it) | Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico | |
| MX9306311A (es) | Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen | |
| IL101358A0 (en) | Crystalline tiagabine hydrochloride monohydrate,its preparation and pharmaceutical compositions containing it | |
| HU9201789D0 (en) | Process for the production of substituted diamino-phtalimides and their analogues | |
| ATE121949T1 (de) | 5,10-methylentetrahydrofolsäure-cyclodextrin- einschlussverbindungen. | |
| MX9301157A (es) | Derivados de bencimidazolona, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. | |
| IT1256238B (it) | Derivati del benzofuranilimidazolo, un procedimento per la loro prepazione e composizioni terapeutiche che li contengono | |
| MX9305510A (es) | Compuestos para el tratamiento o profilaxis de desordenes gastrointestinales, cardiovasculares y del sistema nervioso central, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. | |
| ITMI911853A1 (it) | Sale del diclofenac, metodo di preparazione e composizioni farmaceutiche che lo contengono. | |
| DE59010302D1 (de) | R-(-)-1-(5-Hydroxyhexyl)-3-methyl-7-propylxanthin, Verfahren zu dessen Herstellung und diese Verbindung enthaltende Arzneimittel | |
| ES2088661T3 (es) | Bis-naftalimidas fuertemente solubles en agua utiles como agentes anti-cancerigenos. | |
| GR3025797T3 (en) | New carboxylic-acid esters of 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, the preparation of such esters and their use | |
| IL84261A (en) | Pharmaceutical compositions comprising a 2,4-diphenyl 1,3-dioxane derivative and a thromboxane a2 synthetase inhibitor | |
| ES2062214T3 (es) | Derivados de aminooligohidroxi inhibidores de renina. | |
| MX9302303A (es) | Derivados monocuaternarioos de 2,16-bispiperidinilandrostano. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961227 |