IT1246049B - Procedimento per la preparazione di n-(2-ammino-3,5-dibromo-benzil) trans-4-amminocicloesanolo - Google Patents

Procedimento per la preparazione di n-(2-ammino-3,5-dibromo-benzil) trans-4-amminocicloesanolo

Info

Publication number
IT1246049B
IT1246049B IT02250790A IT2250790A IT1246049B IT 1246049 B IT1246049 B IT 1246049B IT 02250790 A IT02250790 A IT 02250790A IT 2250790 A IT2250790 A IT 2250790A IT 1246049 B IT1246049 B IT 1246049B
Authority
IT
Italy
Prior art keywords
aminocyclohexanol
dibromo
trans
benzyl
amino
Prior art date
Application number
IT02250790A
Other languages
English (en)
Other versions
IT9022507A1 (it
IT9022507A0 (it
Inventor
Ildiko Ratzel
Pal Benko
Daniel Bozsing
Antal Tungler
Tibor Mathe
Gyorgyi Kovanyi
Jozsef Petro
Ilona Sztruhar
Gyorgyi Vereckey
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IT9022507A0 publication Critical patent/IT9022507A0/it
Publication of IT9022507A1 publication Critical patent/IT9022507A1/it
Application granted granted Critical
Publication of IT1246049B publication Critical patent/IT1246049B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT02250790A 1989-12-22 1990-12-21 Procedimento per la preparazione di n-(2-ammino-3,5-dibromo-benzil) trans-4-amminocicloesanolo IT1246049B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU896745A HU207834B (en) 1989-12-22 1989-12-22 Process for producing n-/2-amino-3,5-dibromo-benzyl/-trans-4-amino-cyclohexanol

Publications (3)

Publication Number Publication Date
IT9022507A0 IT9022507A0 (it) 1990-12-21
IT9022507A1 IT9022507A1 (it) 1992-06-21
IT1246049B true IT1246049B (it) 1994-11-07

Family

ID=10971988

Family Applications (1)

Application Number Title Priority Date Filing Date
IT02250790A IT1246049B (it) 1989-12-22 1990-12-21 Procedimento per la preparazione di n-(2-ammino-3,5-dibromo-benzil) trans-4-amminocicloesanolo

Country Status (5)

Country Link
JP (1) JPH04217943A (it)
AT (1) AT400435B (it)
GB (1) GB2239241B (it)
HU (1) HU207834B (it)
IT (1) IT1246049B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102351720B (zh) * 2011-10-21 2013-11-06 南京理工大学 一种简易高效的氨溴素合成方法
CN102964257B (zh) * 2012-11-24 2014-08-06 沈阳新马药业有限公司 一种盐酸氨溴索化合物及其药物组合物
CN109970579A (zh) * 2019-04-22 2019-07-05 浙江海洲制药有限公司 一种制备盐酸氨溴索的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2218647A1 (de) * 1972-04-18 1973-10-25 Thomae Gmbh Dr K Neues verfahren zur herstellung von n-(trans-4-hydroxy-cyclohexyl)-(2-amino3,5-dibrom-benzyl)-amin
DE3366070D1 (en) * 1983-06-29 1986-10-16 Heumann Ludwig & Co Gmbh Process for the preparation of 2-amino-3,5-dibromobenzyl amines

Also Published As

Publication number Publication date
HU207834B (en) 1993-06-28
ATA261990A (de) 1995-05-15
HU896745D0 (en) 1990-03-28
GB9027815D0 (en) 1991-02-13
IT9022507A1 (it) 1992-06-21
GB2239241B (en) 1993-07-14
JPH04217943A (ja) 1992-08-07
HUT58274A (en) 1992-02-28
IT9022507A0 (it) 1990-12-21
GB2239241A (en) 1991-06-26
AT400435B (de) 1995-12-27

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19941228