GB9027815D0 - Novel process for the preparation of n-(2-amino-3,5-dibromobenzyl)-trans-4-amino-cyclohexanol - Google Patents
Novel process for the preparation of n-(2-amino-3,5-dibromobenzyl)-trans-4-amino-cyclohexanolInfo
- Publication number
- GB9027815D0 GB9027815D0 GB909027815A GB9027815A GB9027815D0 GB 9027815 D0 GB9027815 D0 GB 9027815D0 GB 909027815 A GB909027815 A GB 909027815A GB 9027815 A GB9027815 A GB 9027815A GB 9027815 D0 GB9027815 D0 GB 9027815D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- dibromobenzyl
- cyclohexanol
- trans
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU896745A HU207834B (en) | 1989-12-22 | 1989-12-22 | Process for producing n-/2-amino-3,5-dibromo-benzyl/-trans-4-amino-cyclohexanol |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB9027815D0 true GB9027815D0 (en) | 1991-02-13 |
| GB2239241A GB2239241A (en) | 1991-06-26 |
| GB2239241B GB2239241B (en) | 1993-07-14 |
Family
ID=10971988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB9027815A Expired - Fee Related GB2239241B (en) | 1989-12-22 | 1990-12-21 | Novel process for the preparation of n-(2-amino-3,5-dibromobenzyl)-trans-4-amino-cyclohexanol |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPH04217943A (en) |
| AT (1) | AT400435B (en) |
| GB (1) | GB2239241B (en) |
| HU (1) | HU207834B (en) |
| IT (1) | IT1246049B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102351720B (en) * | 2011-10-21 | 2013-11-06 | 南京理工大学 | Simple and efficient ambroxol synthesis method |
| CN102964257B (en) * | 2012-11-24 | 2014-08-06 | 沈阳新马药业有限公司 | Ambroxol hydrochloride compound and medicine composition thereof |
| CN109970579A (en) * | 2019-04-22 | 2019-07-05 | 浙江海洲制药有限公司 | A method of preparing ambroxol hydrochloride |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2218647A1 (en) * | 1972-04-18 | 1973-10-25 | Thomae Gmbh Dr K | Secretolytic n-(trans-4-hydroxycyclohexyl)-2-amino-3,5- - dibromobenzylamine prepn - by redn of n-(2-amino-3,5-dibromobenzylide |
| EP0130224B1 (en) * | 1983-06-29 | 1986-09-10 | LUDWIG HEUMANN & CO GMBH | Process for the preparation of 2-amino-3,5-dibromobenzyl amines |
-
1989
- 1989-12-22 HU HU896745A patent/HU207834B/en not_active IP Right Cessation
-
1990
- 1990-12-21 GB GB9027815A patent/GB2239241B/en not_active Expired - Fee Related
- 1990-12-21 AT AT0261990A patent/AT400435B/en not_active IP Right Cessation
- 1990-12-21 IT IT02250790A patent/IT1246049B/en active IP Right Grant
- 1990-12-21 JP JP2412592A patent/JPH04217943A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HUT58274A (en) | 1992-02-28 |
| HU207834B (en) | 1993-06-28 |
| AT400435B (en) | 1995-12-27 |
| HU896745D0 (en) | 1990-03-28 |
| IT1246049B (en) | 1994-11-07 |
| ATA261990A (en) | 1995-05-15 |
| IT9022507A0 (en) | 1990-12-21 |
| GB2239241B (en) | 1993-07-14 |
| JPH04217943A (en) | 1992-08-07 |
| GB2239241A (en) | 1991-06-26 |
| IT9022507A1 (en) | 1992-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19961221 |