ATA261990A - METHOD FOR PRODUCING N-(2-AMINO-3,5-DIBROMOEBENZYL)-TRANS-4-AMINOCYCLOHEXANOL - Google Patents

METHOD FOR PRODUCING N-(2-AMINO-3,5-DIBROMOEBENZYL)-TRANS-4-AMINOCYCLOHEXANOL

Info

Publication number
ATA261990A
ATA261990A AT0261990A AT261990A ATA261990A AT A261990 A ATA261990 A AT A261990A AT 0261990 A AT0261990 A AT 0261990A AT 261990 A AT261990 A AT 261990A AT A261990 A ATA261990 A AT A261990A
Authority
AT
Austria
Prior art keywords
dibromoebenzyl
aminocyclohexanol
trans
amino
producing
Prior art date
Application number
AT0261990A
Other languages
German (de)
Other versions
AT400435B (en
Inventor
Ildiko Chem Ing Dr Ratz
Pal Chem Ing Dr Benko
Daniel Chem Ing Dr Bozsing
Antal Chem Ing Dr Tungler
Tibor Chem Ing Dr Mathe
Gyoergyi Chem Ing Dr Kovanyi
Jozsef Chem Ing Dr Petro
Ilona Chem Ing Dr Sztruhar
Gyoergyi Chem Ing Vereczkey
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ATA261990A publication Critical patent/ATA261990A/en
Application granted granted Critical
Publication of AT400435B publication Critical patent/AT400435B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT0261990A 1989-12-22 1990-12-21 METHOD FOR PRODUCING N-(2-AMINO-3,5-DIBROMOEBENZYL)-TRANS-4-AMINOCYCLOHEXANOL AT400435B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU896745A HU207834B (en) 1989-12-22 1989-12-22 Process for producing n-/2-amino-3,5-dibromo-benzyl/-trans-4-amino-cyclohexanol

Publications (2)

Publication Number Publication Date
ATA261990A true ATA261990A (en) 1995-05-15
AT400435B AT400435B (en) 1995-12-27

Family

ID=10971988

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0261990A AT400435B (en) 1989-12-22 1990-12-21 METHOD FOR PRODUCING N-(2-AMINO-3,5-DIBROMOEBENZYL)-TRANS-4-AMINOCYCLOHEXANOL

Country Status (5)

Country Link
JP (1) JPH04217943A (en)
AT (1) AT400435B (en)
GB (1) GB2239241B (en)
HU (1) HU207834B (en)
IT (1) IT1246049B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102351720B (en) * 2011-10-21 2013-11-06 南京理工大学 Simple and efficient ambroxol synthesis method
CN102964257B (en) * 2012-11-24 2014-08-06 沈阳新马药业有限公司 Ambroxol hydrochloride compound and medicine composition thereof
CN109970579A (en) * 2019-04-22 2019-07-05 浙江海洲制药有限公司 A method of preparing ambroxol hydrochloride

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2218647A1 (en) * 1972-04-18 1973-10-25 Thomae Gmbh Dr K Secretolytic n-(trans-4-hydroxycyclohexyl)-2-amino-3,5- - dibromobenzylamine prepn - by redn of n-(2-amino-3,5-dibromobenzylide
DE3366070D1 (en) * 1983-06-29 1986-10-16 Heumann Ludwig & Co Gmbh Process for the preparation of 2-amino-3,5-dibromobenzyl amines

Also Published As

Publication number Publication date
GB2239241B (en) 1993-07-14
GB2239241A (en) 1991-06-26
AT400435B (en) 1995-12-27
HU207834B (en) 1993-06-28
GB9027815D0 (en) 1991-02-13
IT9022507A1 (en) 1992-06-21
IT1246049B (en) 1994-11-07
JPH04217943A (en) 1992-08-07
IT9022507A0 (en) 1990-12-21
HU896745D0 (en) 1990-03-28
HUT58274A (en) 1992-02-28

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Legal Events

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