HUT58274A - Process for producing n-(2-amino-3,5-dibromo-benzyl)-trans-4-amino-cyclohexanol - Google Patents

Process for producing n-(2-amino-3,5-dibromo-benzyl)-trans-4-amino-cyclohexanol

Info

Publication number
HUT58274A
HUT58274A HU896745A HU674589A HUT58274A HU T58274 A HUT58274 A HU T58274A HU 896745 A HU896745 A HU 896745A HU 674589 A HU674589 A HU 674589A HU T58274 A HUT58274 A HU T58274A
Authority
HU
Hungary
Prior art keywords
amino
dibromo
cyclohexanol
trans
benzyl
Prior art date
Application number
HU896745A
Other languages
Hungarian (hu)
Other versions
HU896745D0 (en
HU207834B (en
Inventor
Simonek Ildiko Ratzne
Pal Benko
Daniel Bozsing
Antal Tungler
Tibor Mathe
Dr Lax Gyoergyi Kovanyine
Jozsef Petro
Ilona Sztruhar
Donath Gyoergyi Vereczkeyne
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU896745A priority Critical patent/HU207834B/en
Publication of HU896745D0 publication Critical patent/HU896745D0/en
Priority to AT0261990A priority patent/AT400435B/en
Priority to JP2412592A priority patent/JPH04217943A/en
Priority to GB9027815A priority patent/GB2239241B/en
Priority to IT02250790A priority patent/IT1246049B/en
Publication of HUT58274A publication Critical patent/HUT58274A/en
Publication of HU207834B publication Critical patent/HU207834B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HU896745A 1989-12-22 1989-12-22 Process for producing n-/2-amino-3,5-dibromo-benzyl/-trans-4-amino-cyclohexanol HU207834B (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
HU896745A HU207834B (en) 1989-12-22 1989-12-22 Process for producing n-/2-amino-3,5-dibromo-benzyl/-trans-4-amino-cyclohexanol
AT0261990A AT400435B (en) 1989-12-22 1990-12-21 METHOD FOR PRODUCING N-(2-AMINO-3,5-DIBROMOEBENZYL)-TRANS-4-AMINOCYCLOHEXANOL
JP2412592A JPH04217943A (en) 1989-12-22 1990-12-21 N-(2-amino-3,5-dibromobenzyl)-trans-4-aminocyclohexanol and process for producing same
GB9027815A GB2239241B (en) 1989-12-22 1990-12-21 Novel process for the preparation of n-(2-amino-3,5-dibromobenzyl)-trans-4-amino-cyclohexanol
IT02250790A IT1246049B (en) 1989-12-22 1990-12-21 PROCEDURE FOR THE PREPARATION OF N- (2-AMINO-3,5-DIBROMO-BENZYL) TRANS-4-AMINOCYCLOHEXANOL

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU896745A HU207834B (en) 1989-12-22 1989-12-22 Process for producing n-/2-amino-3,5-dibromo-benzyl/-trans-4-amino-cyclohexanol

Publications (3)

Publication Number Publication Date
HU896745D0 HU896745D0 (en) 1990-03-28
HUT58274A true HUT58274A (en) 1992-02-28
HU207834B HU207834B (en) 1993-06-28

Family

ID=10971988

Family Applications (1)

Application Number Title Priority Date Filing Date
HU896745A HU207834B (en) 1989-12-22 1989-12-22 Process for producing n-/2-amino-3,5-dibromo-benzyl/-trans-4-amino-cyclohexanol

Country Status (5)

Country Link
JP (1) JPH04217943A (en)
AT (1) AT400435B (en)
GB (1) GB2239241B (en)
HU (1) HU207834B (en)
IT (1) IT1246049B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102351720B (en) * 2011-10-21 2013-11-06 南京理工大学 Simple and efficient ambroxol synthesis method
CN102964257B (en) * 2012-11-24 2014-08-06 沈阳新马药业有限公司 Ambroxol hydrochloride compound and medicine composition thereof
CN109970579A (en) * 2019-04-22 2019-07-05 浙江海洲制药有限公司 A method of preparing ambroxol hydrochloride

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2218647A1 (en) * 1972-04-18 1973-10-25 Thomae Gmbh Dr K Secretolytic n-(trans-4-hydroxycyclohexyl)-2-amino-3,5- - dibromobenzylamine prepn - by redn of n-(2-amino-3,5-dibromobenzylide
ATE22069T1 (en) * 1983-06-29 1986-09-15 Heumann Ludwig & Co Gmbh PROCESS FOR THE PREPARATION OF 2-AMINO-3,5DIBROMOBENZYLAMINES.

Also Published As

Publication number Publication date
GB2239241A (en) 1991-06-26
IT1246049B (en) 1994-11-07
JPH04217943A (en) 1992-08-07
GB9027815D0 (en) 1991-02-13
HU896745D0 (en) 1990-03-28
ATA261990A (en) 1995-05-15
IT9022507A0 (en) 1990-12-21
AT400435B (en) 1995-12-27
GB2239241B (en) 1993-07-14
HU207834B (en) 1993-06-28
IT9022507A1 (en) 1992-06-21

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee