IS6897A - Aðferðir til að framleiða útskipt 2-(2-pýridýlmetýl)súlfinýl-1H-bensimídasól - Google Patents

Aðferðir til að framleiða útskipt 2-(2-pýridýlmetýl)súlfinýl-1H-bensimídasól

Info

Publication number
IS6897A
IS6897A IS6897A IS6897A IS6897A IS 6897 A IS6897 A IS 6897A IS 6897 A IS6897 A IS 6897A IS 6897 A IS6897 A IS 6897A IS 6897 A IS6897 A IS 6897A
Authority
IS
Iceland
Prior art keywords
sulphinyl
pyridylmethyl
benzimidazole
exchanged
preparing
Prior art date
Application number
IS6897A
Other languages
English (en)
Inventor
Avrutov Ilya
Mendelovici Marioara
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of IS6897A publication Critical patent/IS6897A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IS6897A 2001-02-02 2003-07-29 Aðferðir til að framleiða útskipt 2-(2-pýridýlmetýl)súlfinýl-1H-bensimídasól IS6897A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26616201P 2001-02-02 2001-02-02
PCT/US2002/003225 WO2002062786A1 (en) 2001-02-02 2002-02-04 Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1h-benzimidazoles

Publications (1)

Publication Number Publication Date
IS6897A true IS6897A (is) 2003-07-29

Family

ID=23013433

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6897A IS6897A (is) 2001-02-02 2003-07-29 Aðferðir til að framleiða útskipt 2-(2-pýridýlmetýl)súlfinýl-1H-bensimídasól

Country Status (19)

Country Link
US (3) US7129358B2 (is)
EP (2) EP1970374A1 (is)
JP (1) JP2004524303A (is)
KR (1) KR20040029966A (is)
CN (3) CN100347167C (is)
CA (1) CA2436467A1 (is)
CZ (1) CZ20032351A3 (is)
DE (1) DE02706135T1 (is)
ES (1) ES2209678T1 (is)
HR (1) HRP20030691A2 (is)
HU (1) HUP0303144A3 (is)
IS (1) IS6897A (is)
MX (1) MXPA03006904A (is)
NO (1) NO20033433L (is)
PL (1) PL368563A1 (is)
SK (1) SK10792003A3 (is)
WO (1) WO2002062786A1 (is)
YU (1) YU61103A (is)
ZA (1) ZA200305652B (is)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100347167C (zh) * 2001-02-02 2007-11-07 特瓦制药工业有限公司 取代的2-(2-吡啶基甲基)亚磺酰基-1h-苯并咪唑化合物的生产方法
CA2480352A1 (en) * 2002-03-27 2003-10-09 Teva Pharmaceutical Industries Ltd. Lansoprazole polymorphs and processes for preparation thereof
EP1467987A1 (en) * 2002-07-26 2004-10-20 Teva Pharmaceutical Industries Ltd. Preparation of lansoprazole and related compounds
JP2006500380A (ja) * 2002-08-21 2006-01-05 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾールの精製方法
WO2004046135A1 (en) * 2002-11-18 2004-06-03 Teva Pharmaceutical Industries Ltd. Stable lansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol
US7507829B2 (en) * 2002-12-19 2009-03-24 Teva Pharmaceuticals Industries, Ltd Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
CA2515130A1 (en) * 2003-02-05 2004-08-26 Teva Pharmaceutical Industries Ltd. Method of stabilizing lansoprazole
CA2518999A1 (en) * 2003-03-12 2004-09-23 Teva Pharmaceutical Industries Ltd Crystalline and amorphous solids of pantoprazole and processes for their preparation
WO2004111029A2 (en) * 2003-06-10 2004-12-23 Teva Pharmaceutical Industries Ltd. Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
FR2871800B1 (fr) * 2004-06-17 2006-08-25 Sidem Pharma Sa Sa Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
ZA200706613B (en) * 2004-12-16 2009-03-25 Cipla Ltd Process
EP1681056A1 (en) 2005-01-14 2006-07-19 Krka Tovarna Zdravil, D.D., Novo Mesto Process for preparing lansoprazole
EP1893602A2 (en) * 2005-05-06 2008-03-05 Medichem, S.A. Pantoprazole free acid form iii
CN1919844B (zh) * 2006-09-01 2010-05-12 武汉工程大学 水相氧化合成兰索拉唑的方法
US20100113527A1 (en) * 2008-09-30 2010-05-06 Teva Pharmaceutical Industries Ltd. Crystalline forms of dexlansoprazole
WO2010134099A1 (en) * 2009-05-21 2010-11-25 Cadila Healthcare Limited One pot process for preparing omeprazole and related compounds
CN108623564B (zh) * 2017-03-17 2022-11-04 江苏豪森药业集团有限公司 一种雷贝拉唑类似物的制备方法
CN111072633A (zh) * 2019-12-19 2020-04-28 山东达因海洋生物制药股份有限公司 一种埃索美拉唑镁三水合物的制备方法
CN112174934B (zh) * 2020-10-15 2023-12-22 成都百泉生物医药科技有限公司 一种奥美拉唑的合成方法及其合成设备

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1140119A (en) 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
GB2069492B (en) 1980-02-20 1984-02-29 Wyeth John & Brother Ltd Sulphur compounds
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
SE9002043D0 (sv) 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
NZ244301A (en) * 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
ES2063705B1 (es) 1993-06-14 1995-07-16 S A L V A T Lab Sa Intermedio para la sintesis de lansoprazol y su procedimiento de obtencion.
SK283805B6 (sk) * 1996-09-09 2004-02-03 Slovakofarma, A. S. Spôsob prípravy omeprazolu
SE9704183D0 (sv) * 1997-11-14 1997-11-14 Astra Ab New process
PL195266B1 (pl) * 1997-12-08 2007-08-31 Altana Pharma Ag Jednostka związku aktywnego nietrwałego w środowisku kwaśnym, sposób jej otrzymywania, czopki zawierające aktywny związek nietrwały w środowisku kwaśnym oraz sposób ich otrzymywania
GB9805558D0 (en) * 1998-03-17 1998-05-13 Knoll Ag Chemical process`
US6303787B1 (en) * 1998-05-27 2001-10-16 Natco Pharma Limited Intermediates and an improved process for the preparation of Omeprazole employing the said intermediates
SI20019A (sl) * 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
JP4047993B2 (ja) * 1999-01-04 2008-02-13 理想科学工業株式会社 孔版印刷方法
US6245913B1 (en) * 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
ES2163372B1 (es) * 2000-03-13 2003-05-01 Esteve Quimica Sa Procedimiento de oxidacion de un grupo tioeter a sulfoxido.
CN100347167C (zh) 2001-02-02 2007-11-07 特瓦制药工业有限公司 取代的2-(2-吡啶基甲基)亚磺酰基-1h-苯并咪唑化合物的生产方法

Also Published As

Publication number Publication date
ZA200305652B (en) 2004-07-22
EP1363901A4 (en) 2005-08-31
NO20033433D0 (no) 2003-08-01
CN1489585A (zh) 2004-04-14
SK10792003A3 (sk) 2004-07-07
US20080091024A1 (en) 2008-04-17
US7129358B2 (en) 2006-10-31
HUP0303144A2 (hu) 2004-03-01
CN1781918A (zh) 2006-06-07
DE02706135T1 (de) 2004-05-19
WO2002062786A1 (en) 2002-08-15
EP1970374A1 (en) 2008-09-17
HRP20030691A2 (en) 2005-04-30
ES2209678T1 (es) 2004-07-01
PL368563A1 (en) 2005-04-04
CZ20032351A3 (cs) 2004-08-18
NO20033433L (no) 2003-09-25
EP1363901A1 (en) 2003-11-26
MXPA03006904A (es) 2004-12-06
CN1876647A (zh) 2006-12-13
YU61103A (sh) 2006-05-25
US20030036554A1 (en) 2003-02-20
CA2436467A1 (en) 2002-08-15
CN100347167C (zh) 2007-11-07
JP2004524303A (ja) 2004-08-12
HUP0303144A3 (en) 2007-08-28
US20060293363A1 (en) 2006-12-28
KR20040029966A (ko) 2004-04-08

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