IS5382A - Setin 4-oxo-napthyridine-3-karboxamíð sem tengistGABA viðtökum í heila - Google Patents

Setin 4-oxo-napthyridine-3-karboxamíð sem tengistGABA viðtökum í heila

Info

Publication number
IS5382A
IS5382A IS5382A IS5382A IS5382A IS 5382 A IS5382 A IS 5382A IS 5382 A IS5382 A IS 5382A IS 5382 A IS5382 A IS 5382A IS 5382 A IS5382 A IS 5382A
Authority
IS
Iceland
Prior art keywords
napthyridine
carboxamide
oxo
brain
substituted
Prior art date
Application number
IS5382A
Other languages
English (en)
Icelandic (is)
Inventor
Albaugh Pamela
W. Desimone Robert
Liu Gang
Original Assignee
Neurogen Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corporation filed Critical Neurogen Corporation
Publication of IS5382A publication Critical patent/IS5382A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IS5382A 1997-08-25 2000-02-22 Setin 4-oxo-napthyridine-3-karboxamíð sem tengistGABA viðtökum í heila IS5382A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91818097A 1997-08-25 1997-08-25
PCT/US1998/017513 WO1999010347A1 (en) 1997-08-25 1998-08-24 Substituted 4-oxo-napthyridine-3-carboxamides as gaba brain receptor ligands

Publications (1)

Publication Number Publication Date
IS5382A true IS5382A (is) 2000-02-22

Family

ID=25439933

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5382A IS5382A (is) 1997-08-25 2000-02-22 Setin 4-oxo-napthyridine-3-karboxamíð sem tengistGABA viðtökum í heila

Country Status (24)

Country Link
EP (1) EP1007526A1 (enrdf_load_stackoverflow)
JP (1) JP2001514181A (enrdf_load_stackoverflow)
KR (1) KR20010023313A (enrdf_load_stackoverflow)
CN (1) CN1268136A (enrdf_load_stackoverflow)
AP (1) AP2000001742A0 (enrdf_load_stackoverflow)
AU (1) AU753800B2 (enrdf_load_stackoverflow)
BG (1) BG104192A (enrdf_load_stackoverflow)
BR (1) BR9811362A (enrdf_load_stackoverflow)
CA (1) CA2301599C (enrdf_load_stackoverflow)
EG (1) EG21717A (enrdf_load_stackoverflow)
HU (1) HUP0003258A3 (enrdf_load_stackoverflow)
IL (1) IL134291A0 (enrdf_load_stackoverflow)
IS (1) IS5382A (enrdf_load_stackoverflow)
LV (1) LV12539B (enrdf_load_stackoverflow)
NO (1) NO20000822L (enrdf_load_stackoverflow)
NZ (1) NZ502548A (enrdf_load_stackoverflow)
OA (1) OA11293A (enrdf_load_stackoverflow)
PE (1) PE130999A1 (enrdf_load_stackoverflow)
PL (1) PL338783A1 (enrdf_load_stackoverflow)
SI (1) SI20270A (enrdf_load_stackoverflow)
SK (1) SK2162000A3 (enrdf_load_stackoverflow)
TW (1) TW574221B (enrdf_load_stackoverflow)
WO (1) WO1999010347A1 (enrdf_load_stackoverflow)
YU (1) YU10500A (enrdf_load_stackoverflow)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1177177B1 (en) * 1999-05-06 2005-02-23 Neurogen Corporation Substituted 4-oxo-quinoline-3-carboxamides: gaba brain receptor ligands
US6448246B1 (en) 1999-05-25 2002-09-10 Neurogen Corporation Substituted 4H-1,4-benzothiazine-2-carboxamide: GABA brain receptor ligands
US6559145B2 (en) 2000-07-12 2003-05-06 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US6730682B2 (en) 2000-07-12 2004-05-04 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US6562822B2 (en) 2000-07-12 2003-05-13 Pharmacia & Upjohn Company Heterocyle carboxamides as antiviral agents
ATE345129T1 (de) 2000-10-12 2006-12-15 Merck & Co Inc Aza- und polyaza-naphthalenylcarbonsäureamide als hiv-integrase-hemmer
SK4322003A3 (en) 2000-10-12 2003-09-11 Merck & Co Inc Aza- and polyaza-naphthalenyl carboxamides useful as HIV integrase inhibitors
ATE364385T1 (de) 2000-10-12 2007-07-15 Merck & Co Inc Aza- und polyaza-naphthalenylcarbonsäureamide als hiv-integrase-hemmer
US20020151591A1 (en) * 2000-10-17 2002-10-17 Anabella Villalobos Combination use of acetylcholinesterase inhibitors and GABAa inverse agonists for the treatment of cognitive disorders
OA12554A (en) * 2001-03-01 2006-06-07 Pfizer Prod Inc Use of GABA a inverse agonists in combination withnicotine receptor partial agonists, estrogen, sel ective estrogen modulators, or bitamin E for the treatment of cognitive disorders.
AR036256A1 (es) 2001-08-17 2004-08-25 Merck & Co Inc Sal sodica de un inhibidor de integrasa del vih, procesos para su preparacion, composiciones farmaceuticas que lo contienen y su uso para la manufactura de un medicamento
CA2472372C (en) 2002-01-17 2010-08-17 Melissa Egbertson Hydroxynaphthyridinone carboxamides useful as hiv integrase inhibitors
WO2003077850A2 (en) 2002-03-15 2003-09-25 Merck & Co., Inc. N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7- carboxamides useful as hiv integrase inhibitors
WO2004106336A1 (en) * 2003-05-27 2004-12-09 Pfizer Products Inc. Process for the preparation and purification of 1,5-naphthyridine-3-carboxyamides
WO2004106334A2 (en) * 2003-05-28 2004-12-09 Pfizer Products Inc. Process for the preparation of 1,5-naphthyridine-3-carboxy amides by direct ester amidation
CA2954376C (en) * 2006-10-16 2019-06-11 Bionomics Limited Novel anxiolytic compounds
SI2083811T1 (sl) * 2006-11-22 2017-02-28 Clinical Research Associates, Llc Postopki zdravljenja Downovega sindroma, sindroma krhkega X in avtizma

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204162A1 (es) * 1972-05-08 1975-11-28 Yamanouchi Pharma Co Ltd Proceso para la preparacion de derivados de ampicilina
GB1433774A (en) * 1973-02-26 1976-04-28 Allen & Hanburys Ltd Heterocyclic compounds apparatus for conveying articles
US4374138A (en) * 1981-11-13 1983-02-15 Warner-Lambert Company Antibacterial amide compounds, compositions, and methods of use
DD279887A1 (de) * 1987-07-03 1990-06-20 Inst Pharmakologische Forschun Verfahren zur herstellung von d-alpha-(4(1h)-1,5-naphthyridon-3-carboxamido)-benzylpenicillin und anderen beta-lactamantibiotika
DD279875A1 (de) * 1987-07-03 1990-06-20 Inst Pharmakologische Forschun Verfahren zur herstellung von aktivierten carbonsaeureestern
DD295360A5 (de) * 1987-07-03 1991-10-31 Akad Wissenschaften Verfahren zur Herstellung von aktivierten Carbonsäureestern
JPS6461461A (en) * 1987-09-01 1989-03-08 Otsuka Pharma Co Ltd Benzohetero ring derivative

Also Published As

Publication number Publication date
JP2001514181A (ja) 2001-09-11
OA11293A (en) 2002-11-19
PL338783A1 (en) 2000-11-20
LV12539A (en) 2000-10-20
SK2162000A3 (en) 2001-03-12
BR9811362A (pt) 2000-08-22
CA2301599C (en) 2003-03-25
EP1007526A1 (en) 2000-06-14
AU9117398A (en) 1999-03-16
SI20270A (sl) 2000-12-31
LV12539B (en) 2001-01-20
AP2000001742A0 (en) 2000-02-24
NZ502548A (en) 2002-06-28
PE130999A1 (es) 1999-12-16
EG21717A (en) 2002-02-27
HUP0003258A2 (en) 2001-03-28
WO1999010347A1 (en) 1999-03-04
BG104192A (en) 2001-05-31
TW574221B (en) 2004-02-01
NO20000822L (no) 2000-04-13
KR20010023313A (ko) 2001-03-26
CN1268136A (zh) 2000-09-27
NO20000822D0 (no) 2000-02-18
AU753800B2 (en) 2002-10-31
CA2301599A1 (en) 1999-03-04
IL134291A0 (en) 2001-04-30
YU10500A (sh) 2002-10-18
HUP0003258A3 (en) 2001-05-28

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