IS4111A - Hliðstæð aðferð við framleiðslu á nýjum steróíðafleiðum sem hafa sérvirkni í ristli eða dausgörn - Google Patents

Hliðstæð aðferð við framleiðslu á nýjum steróíðafleiðum sem hafa sérvirkni í ristli eða dausgörn

Info

Publication number
IS4111A
IS4111A IS4111A IS4111A IS4111A IS 4111 A IS4111 A IS 4111A IS 4111 A IS4111 A IS 4111A IS 4111 A IS4111 A IS 4111A IS 4111 A IS4111 A IS 4111A
Authority
IS
Iceland
Prior art keywords
colon
dystrophy
specificity
production
analogous method
Prior art date
Application number
IS4111A
Other languages
English (en)
Inventor
Lennart Brattsand Ralph
Edman Peter
Högberg Thomas
Nilsson Stinabritt
Arne Thalén Bror
Erik Ulmius Jan
Original Assignee
Ab Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9300030A external-priority patent/SE9300030D0/xx
Priority claimed from SE9300082A external-priority patent/SE9300082D0/xx
Application filed by Ab Astra filed Critical Ab Astra
Publication of IS4111A publication Critical patent/IS4111A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
IS4111A 1993-01-08 1993-12-22 Hliðstæð aðferð við framleiðslu á nýjum steróíðafleiðum sem hafa sérvirkni í ristli eða dausgörn IS4111A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9300030A SE9300030D0 (sv) 1993-01-08 1993-01-08 Novel colon- or ileum-specific steroid derivatives
SE9300082A SE9300082D0 (sv) 1993-01-14 1993-01-14 Novel colon- or ileum-specific steroid derivatives

Publications (1)

Publication Number Publication Date
IS4111A true IS4111A (is) 1994-07-09

Family

ID=26661623

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4111A IS4111A (is) 1993-01-08 1993-12-22 Hliðstæð aðferð við framleiðslu á nýjum steróíðafleiðum sem hafa sérvirkni í ristli eða dausgörn

Country Status (22)

Country Link
US (2) US5908833A (is)
EP (1) EP0678097B1 (is)
JP (1) JP3366640B2 (is)
KR (1) KR960700266A (is)
AT (1) ATE183192T1 (is)
BR (1) BR9307746A (is)
CA (1) CA2152374A1 (is)
CZ (1) CZ171095A3 (is)
DK (1) DK0678097T3 (is)
ES (1) ES2137353T3 (is)
FI (1) FI953358A7 (is)
GR (1) GR3031789T3 (is)
HU (1) HU221584B (is)
IS (1) IS4111A (is)
LV (1) LV10961B (is)
NO (1) NO305367B1 (is)
NZ (1) NZ259596A (is)
PL (1) PL178307B1 (is)
RU (1) RU95115547A (is)
SK (1) SK87295A3 (is)
TW (1) TW261615B (is)
WO (1) WO1994015947A1 (is)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
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RU95115547A (ru) * 1993-01-08 1997-06-10 Астра Актиеболаг (SE) Стероидные соединения, способы их получения и фармацевтический препарат
CA2172983A1 (en) * 1993-09-29 1995-04-06 Kei Sugai 21-substituted steroid compound
US6028190A (en) 1994-02-01 2000-02-22 The Regents Of The University Of California Probes labeled with energy transfer coupled dyes
US6166024A (en) 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
WO1999047541A1 (fr) * 1998-03-19 1999-09-23 Nissin Food Products Co., Ltd. Composes steroides glycosyles a substitution en position 21
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
MXPA01011227A (es) 1999-05-04 2002-07-02 Strakan Ltd Glicosidas androgenas y su actividad androgenica.
EP1183014B1 (en) * 1999-06-14 2003-10-08 Cosmo S.p.A. Controlled release and taste masking oral pharmaceutical compositions
US8895064B2 (en) 1999-06-14 2014-11-25 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
WO2001051057A2 (en) * 2000-01-14 2001-07-19 Strakan Limited Glycosides and orthoester glycosides of glucocorticoids and uses thereof
SE0101220D0 (sv) * 2001-04-04 2001-04-04 Astrazeneca Ab New use
EP1625854B1 (en) * 2004-08-09 2008-10-15 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Albumin conjugates containing a glucuronic linker
WO2008100560A2 (en) * 2007-02-14 2008-08-21 University Of Southern California Estrogen receptor modulators, associated pharmaceutical compositions and methods of use
US10154964B2 (en) 2011-09-07 2018-12-18 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
WO2018089373A2 (en) 2016-11-08 2018-05-17 Regeneron Pharmaceuticals, Inc. Steroids and protein-conjugates thereof
AU2018241798B2 (en) * 2017-03-30 2020-04-30 Fruithy Holdings Limited Lactulose glycoside compound and preparation method and use thereof
CA3063871A1 (en) 2017-05-18 2018-11-22 Regeneron Pharmaceuticals, Inc. Cyclodextrin protein drug conjugates
IL274427B2 (en) 2017-11-07 2024-11-01 Regeneron Pharma Hydrophilic linkers for antibody drug conjugates
CA3086926A1 (en) * 2018-01-08 2019-07-11 Regeneron Pharmaceuticals, Inc. Steroids and antibody-conjugates thereof
CA3098453A1 (en) 2018-05-09 2019-11-14 Regeneron Pharmaceuticals, Inc. Anti-msr1 antibodies and methods of use thereof

Family Cites Families (32)

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Publication number Priority date Publication date Assignee Title
US3996359A (en) * 1972-05-19 1976-12-07 Ab Bofors Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
SE378109B (is) * 1972-05-19 1975-08-18 Bofors Ab
US3992534A (en) * 1972-05-19 1976-11-16 Ab Bofors Compositions and method of treating with component B of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steriods
SE378110B (is) * 1972-05-19 1975-08-18 Bofors Ab
US3938233A (en) * 1974-08-12 1976-02-17 Cannon Robert B Heat transfer apparatus
DE2803660A1 (de) * 1978-01-25 1979-07-26 Schering Ag Neue in 17-position substituierte steroide der pregnanreihe, ihre herstellung und verwendung
EP0003341B1 (de) * 1978-01-25 1984-06-27 Schering Aktiengesellschaft 11,17-substituierte Pregnane, ihre Herstellung und Verwendung zur Herstellung von pharmazeutischen Präparaten
US4221787A (en) * 1978-03-28 1980-09-09 Interx Research Corporation Esteramide prodrugs of anti-inflammatory corticosteroids
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4456602A (en) * 1982-08-23 1984-06-26 The Upjohn Company Amine containing ester prodrugs of corticosteroids
US4443440A (en) * 1982-08-30 1984-04-17 The Upjohn Company Amine containing ester prodrugs of corticosteroids
US4472392A (en) * 1983-01-21 1984-09-18 The Upjohn Company Sulfonate containing ester prodrugs of corticosteroids
US4469689A (en) * 1983-03-30 1984-09-04 The Upjohn Company Sulfonate containing ester prodrugs of corticosteroids
WO1984004041A1 (en) * 1983-04-14 1984-10-25 Univ California Colon-specific drug delivery system
US4548922A (en) * 1983-06-06 1985-10-22 Beth Israel Hospital Drug administration
US4959358A (en) * 1983-06-06 1990-09-25 Beth Israel Hospital Assn. Drug administration
SE8306370D0 (sv) * 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
US4588718A (en) * 1984-03-28 1986-05-13 The Upjohn Company Carboxy containing ester prodrugs of corticosteroids
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
US5215979A (en) * 1985-12-19 1993-06-01 Aktiebolaget Draco 16,17-acetalsubstituted pregnane 21-oic acid derivatives
GB8600489D0 (en) * 1986-01-09 1986-02-12 Erba Farmitalia Aminoglycoside steroids
GB8600491D0 (en) * 1986-01-09 1986-02-12 Erba Farmitalia Aminoglycoside norcholanic acid derivatives
GB8600490D0 (en) * 1986-01-09 1986-02-12 Erba Farmitalia Aminoglycoside norcholanic acid lactams
WO1987006936A1 (fr) * 1986-05-12 1987-11-19 Mect Corporation Sialosylcholesterol, procede de preparation et medicament contre les troubles du systeme nerveux
CA1299653C (en) * 1988-07-07 1992-04-28 Markwell Medical Institute, Inc. Biological fluid measuring device
US5643602A (en) * 1989-11-22 1997-07-01 Astra Aktiebolag Oral composition for the treatment of inflammatory bowel disease
SE8903914D0 (sv) * 1989-11-22 1989-11-22 Draco Ab Oral composition for the treatment of inflammatory bowel diseases
US5888995A (en) * 1991-02-04 1999-03-30 Astra Aktiebolag Steroid esters
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
SE9100342D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroid esters
WO1993022334A1 (en) * 1992-05-04 1993-11-11 Sri International Pharmaceutical compositions and methods for colonic delivery of corticosteroids
RU95115547A (ru) * 1993-01-08 1997-06-10 Астра Актиеболаг (SE) Стероидные соединения, способы их получения и фармацевтический препарат

Also Published As

Publication number Publication date
NZ259596A (en) 1997-04-24
PL309777A1 (en) 1995-11-13
PL178307B1 (pl) 2000-04-28
AU678803B2 (en) 1997-06-12
JPH08505616A (ja) 1996-06-18
JP3366640B2 (ja) 2003-01-14
WO1994015947A1 (en) 1994-07-21
NO305367B1 (no) 1999-05-18
SK87295A3 (en) 1996-04-03
HU221584B (hu) 2002-11-28
AU5844794A (en) 1994-08-15
FI953358L (fi) 1995-07-07
ATE183192T1 (de) 1999-08-15
BR9307746A (pt) 1995-11-14
ES2137353T3 (es) 1999-12-16
HU9502087D0 (en) 1995-09-28
LV10961A (lv) 1995-12-20
KR960700266A (ko) 1996-01-19
NO952683L (no) 1995-07-06
US6140308A (en) 2000-10-31
GR3031789T3 (en) 2000-02-29
US5908833A (en) 1999-06-01
TW261615B (is) 1995-11-01
EP0678097A1 (en) 1995-10-25
DK0678097T3 (da) 2000-02-07
CA2152374A1 (en) 1994-07-21
EP0678097B1 (en) 1999-08-11
CZ171095A3 (en) 1996-01-17
FI953358A0 (fi) 1995-07-07
FI953358A7 (fi) 1995-07-07
NO952683D0 (no) 1995-07-06
RU95115547A (ru) 1997-06-10
LV10961B (en) 1996-08-20
HUT73227A (en) 1996-07-29

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