IN2015MN00139A - - Google Patents

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Publication number
IN2015MN00139A
IN2015MN00139A IN139MUN2015A IN2015MN00139A IN 2015MN00139 A IN2015MN00139 A IN 2015MN00139A IN 139MUN2015 A IN139MUN2015 A IN 139MUN2015A IN 2015MN00139 A IN2015MN00139 A IN 2015MN00139A
Authority
IN
India
Prior art keywords
protein
fragments
present
hetero dimeric
immunoglobulinvariants
Prior art date
Application number
Other languages
English (en)
Inventor
Stanislas Blein
Fabrizio Comper
Romain Ollier
Paul Wassmann
Original Assignee
Glenmark Pharmaceuticals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals Sa filed Critical Glenmark Pharmaceuticals Sa
Publication of IN2015MN00139A publication Critical patent/IN2015MN00139A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/522—CH1 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IN139MUN2015 2012-09-25 2013-09-25 IN2015MN00139A (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261705278P 2012-09-25 2012-09-25
PCT/EP2013/069989 WO2014049003A1 (en) 2012-09-25 2013-09-25 Purification of hetero-dimeric immunoglobulins

Publications (1)

Publication Number Publication Date
IN2015MN00139A true IN2015MN00139A (xx) 2015-10-16

Family

ID=49237223

Family Applications (1)

Application Number Title Priority Date Filing Date
IN139MUN2015 IN2015MN00139A (xx) 2012-09-25 2013-09-25

Country Status (11)

Country Link
US (2) US20150239991A1 (xx)
EP (2) EP2900696A1 (xx)
JP (5) JP2015529236A (xx)
KR (1) KR20150076172A (xx)
CN (1) CN104968685A (xx)
AU (2) AU2013322710A1 (xx)
CA (2) CA2886036A1 (xx)
HK (1) HK1215950A1 (xx)
IL (2) IL237872B (xx)
IN (1) IN2015MN00139A (xx)
WO (1) WO2014049003A1 (xx)

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US20210269509A1 (en) 2018-06-22 2021-09-02 Genmab A/S Method for producing a controlled mixture of two or more different antibodies
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Also Published As

Publication number Publication date
AU2013322710A2 (en) 2015-05-07
AU2018204314B2 (en) 2020-05-14
JP2019073512A (ja) 2019-05-16
IL269207A (en) 2019-11-28
JP2020105203A (ja) 2020-07-09
US20200010568A1 (en) 2020-01-09
IL237872B (en) 2019-09-26
JP2018104444A (ja) 2018-07-05
IL237872A0 (en) 2015-05-31
HK1215950A1 (zh) 2016-09-30
WO2014049003A1 (en) 2014-04-03
JP6856610B2 (ja) 2021-04-07
CA3061557A1 (en) 2014-04-03
CA2886036A1 (en) 2014-04-03
IL269207B (en) 2022-02-01
US20150239991A1 (en) 2015-08-27
KR20150076172A (ko) 2015-07-06
EP3401337A1 (en) 2018-11-14
EP2900696A1 (en) 2015-08-05
CN104968685A (zh) 2015-10-07
AU2018204314A1 (en) 2018-07-05
JP2015529236A (ja) 2015-10-05
AU2013322710A1 (en) 2015-04-16
JP2022116326A (ja) 2022-08-09

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