IN2015DN04302A - - Google Patents

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Publication number
IN2015DN04302A
IN2015DN04302A IN4302DEN2015A IN2015DN04302A IN 2015DN04302 A IN2015DN04302 A IN 2015DN04302A IN 4302DEN2015 A IN4302DEN2015 A IN 4302DEN2015A IN 2015DN04302 A IN2015DN04302 A IN 2015DN04302A
Authority
IN
India
Prior art keywords
provides
glycerol
production
pathway
ethanol
Prior art date
Application number
Other languages
English (en)
Inventor
Iv Arthur J Shaw
Aaron Argyros
Trisha Barrett
Original Assignee
Lallemand Hungary Liquidity Man Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lallemand Hungary Liquidity Man Llc filed Critical Lallemand Hungary Liquidity Man Llc
Publication of IN2015DN04302A publication Critical patent/IN2015DN04302A/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1022Transferases (2.) transferring aldehyde or ketonic groups (2.2)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217Phosphotransferases with a carboxyl group as acceptor (2.7.2)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
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    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001Alcohol dehydrogenase (1.1.1.1)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01008Glycerol-3-phosphate dehydrogenase (NAD+) (1.1.1.8)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0101Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
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    • C12Y197/00Other oxidoreductases (1.97)
    • C12Y197/01Other oxidoreductases (1.97) other oxidoreductases (1.97.1)
    • C12Y197/01004[Formate-C-acetyltransferase]-activating enzyme (1.97.1.4)
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    • C12YENZYMES
    • C12Y202/00Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01Transketolases and transaldolases (2.2.1)
    • C12Y202/01001Transketolase (2.2.1.1)
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    • C12YENZYMES
    • C12Y202/00Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01Transketolases and transaldolases (2.2.1)
    • C12Y202/01002Transaldolase (2.2.1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008Phosphate acetyltransferase (2.3.1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01054Formate C-acetyltransferase (2.3.1.54), i.e. pyruvate formate-lyase or PFL
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    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02012Acetate kinase (diphosphate) (2.7.2.12)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03021Glycerol-1-phosphatase (3.1.3.21)
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    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • C12Y401/01001Pyruvate decarboxylase (4.1.1.1)
    • CCHEMISTRY; METALLURGY
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    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/02Aldehyde-lyases (4.1.2)
    • C12Y401/02009Phosphoketolase (4.1.2.9)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/02Aldehyde-lyases (4.1.2)
    • C12Y401/02022Fructose-6-phosphate phosphoketolase (4.1.2.22)
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    • C12Y501/00Racemaces and epimerases (5.1)
    • C12Y501/03Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • C12Y501/03001Ribulose-phosphate 3-epimerase (5.1.3.1)
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    • C12Y503/00Intramolecular oxidoreductases (5.3)
    • C12Y503/01Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01006Ribose-5-phosphate isomerase (5.3.1.6)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IN4302DEN2015 2012-11-20 2013-11-20 IN2015DN04302A (OSRAM)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261728450P 2012-11-20 2012-11-20
US201361792731P 2013-03-15 2013-03-15
PCT/US2013/070964 WO2014081803A1 (en) 2012-11-20 2013-11-20 An electron consuming ethanol production pathway to displace glycerol formation in s. cerevisiae

Publications (1)

Publication Number Publication Date
IN2015DN04302A true IN2015DN04302A (OSRAM) 2015-10-16

Family

ID=49725370

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4302DEN2015 IN2015DN04302A (OSRAM) 2012-11-20 2013-11-20

Country Status (8)

Country Link
US (4) US9988650B2 (OSRAM)
EP (1) EP2922950B1 (OSRAM)
CN (1) CN105121637B (OSRAM)
BR (1) BR112015011544B1 (OSRAM)
CA (1) CA2891455C (OSRAM)
DK (1) DK2922950T3 (OSRAM)
IN (1) IN2015DN04302A (OSRAM)
WO (1) WO2014081803A1 (OSRAM)

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FI3033413T4 (fi) * 2013-08-15 2023-08-31 Menetelmiä tuotesaannon ja tuotannon parantamiseksi mikro-organismissa glyserolikierrätyksellä
EP3074504B1 (en) 2013-11-25 2024-12-25 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
WO2015084633A1 (en) 2013-12-03 2015-06-11 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
EP3122876B1 (en) 2014-03-28 2020-11-25 Danisco US Inc. Altered host cell pathway for improved ethanol production
US10760105B2 (en) 2014-12-30 2020-09-01 Novogy, Inc. Enhanced production of core lipids in oleaginous yeasts
BR112017016821A2 (pt) 2015-02-06 2018-04-03 Cargill Inc polipeptídeo, ácido nucleico, vetor, célula hospedeira, meio de fermentação, uso de polipeptídeo, composição de ração e método de fermentação
US10344288B2 (en) 2015-03-27 2019-07-09 Cargill, Incorporated Glucoamylase-modified yeast strains and methods for bioproduct production
BR112018011902A2 (pt) 2015-12-17 2018-12-04 Cargill Inc método de fermentação, levedura geneticamente modificada, construto de ácido nucleico, vetor, célula hospedeira, meio de fermentação e utilização da levedura geneticamente modificada
WO2017189421A1 (en) * 2016-04-28 2017-11-02 Danisco Us Inc. Redox balancing in yeast
EP3267345A1 (en) * 2016-07-06 2018-01-10 European Molecular Biology Laboratory Methods for adaptive laboratory evolution
WO2018027131A1 (en) 2016-08-05 2018-02-08 Cargill, Incorporated Leader-modified glucoamylase polypeptides and engineered yeast strains having enhanced bioproduct production
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CN107083623B (zh) * 2017-06-14 2023-01-10 朱月眉 一种串珠装置及具有该装置的绣珠机
BR112020004921A2 (pt) * 2017-09-26 2020-09-15 Dsm Ip Assets B.V. cepa consumidora de ácido acético
US20220073942A1 (en) * 2018-12-06 2022-03-10 Pfizer Inc. Cells with reduced inhibitor production and methods of use thereof
WO2021022097A1 (en) * 2019-08-01 2021-02-04 Danisco Us Inc Over-expression of adh5p for increased ethanol production by yeast
BR112022026825A2 (pt) * 2020-07-10 2023-01-24 Lallemand Hungary Liquidity Man Llc Processo para reduzir a atividade de contaminação microbiana em um meio de levedura
US11692210B2 (en) 2020-09-01 2023-07-04 Braskem S.A. Anaerobic fermentative production of furandicarboxylic acid
MX2024000511A (es) 2021-07-12 2024-03-11 Danisco Us Inc Celula de levadura recombinante.
MX2024000606A (es) 2021-07-12 2024-01-30 Danisco Us Inc Celula de levadura recombinante.
US20250277240A1 (en) 2021-07-12 2025-09-04 Danisco Us Inc. Recombinant yeast cell
US20240409964A1 (en) * 2021-10-11 2024-12-12 Danstar Ferment Ag Recombinant yeast cell having increased pyruvate decarboxylase activity
WO2023079048A1 (en) 2021-11-04 2023-05-11 Dsm Ip Assets B.V. Process for the production of ethanol and recombinant yeast cell
CN118176296A (zh) 2021-11-04 2024-06-11 丹尼斯科美国公司 重组酵母细胞
EP4426823A1 (en) 2021-11-04 2024-09-11 Danisco Us Inc Variant polypeptide and recombinant yeast cell
WO2023208762A2 (en) 2022-04-25 2023-11-02 Dsm Ip Assets B.V. Mutant yeast cell and process for the production of ethanol
CN120435548A (zh) * 2022-12-01 2025-08-05 匹克生物酶高科技有限公司 用于解毒内源醛类的食品和药物组合物
CN120475911A (zh) * 2022-12-01 2025-08-12 匹克生物酶高科技有限公司 包含新的醛脱氢酶的用于改善记忆和认知功能的食品和药物组合物
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WO2025133860A1 (en) 2023-12-21 2025-06-26 Danstar Ferment Ag Increased production of acetyl-phosphate and products derived therefrom in yeasts

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IN2015DN04302A (OSRAM) * 2012-11-20 2015-10-16 Lallemand Hungary Liquidity Man Llc
EP2971027B1 (en) 2013-03-15 2019-01-30 Amyris, Inc. Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds

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Publication number Publication date
BR112015011544A2 (OSRAM) 2017-08-15
US9988650B2 (en) 2018-06-05
US10465208B2 (en) 2019-11-05
US20200157579A1 (en) 2020-05-21
CA2891455C (en) 2022-07-05
DK2922950T3 (da) 2021-05-03
CN105121637A (zh) 2015-12-02
US20210147882A1 (en) 2021-05-20
US20160273004A1 (en) 2016-09-22
US11655484B2 (en) 2023-05-23
BR112015011544B1 (pt) 2022-08-16
EP2922950A1 (en) 2015-09-30
EP2922950B1 (en) 2021-04-07
CN105121637B (zh) 2019-12-24
US20180142267A1 (en) 2018-05-24
CA2891455A1 (en) 2014-05-30
WO2014081803A1 (en) 2014-05-30

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