IN2015DN01046A - - Google Patents
Download PDFInfo
- Publication number
- IN2015DN01046A IN2015DN01046A IN1046DEN2015A IN2015DN01046A IN 2015DN01046 A IN2015DN01046 A IN 2015DN01046A IN 1046DEN2015 A IN1046DEN2015 A IN 1046DEN2015A IN 2015DN01046 A IN2015DN01046 A IN 2015DN01046A
- Authority
- IN
- India
- Prior art keywords
- breast cancer
- treating
- subject
- subject suffering
- positive
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 abstract 11
- 208000026310 Breast neoplasm Diseases 0.000 abstract 10
- 229940083324 Selective androgen receptor modulator Drugs 0.000 abstract 3
- 239000000849 selective androgen receptor modulator Substances 0.000 abstract 3
- BFYIZQONLCFLEV-DAELLWKTSA-N Aromasine Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC(=C)C2=C1 BFYIZQONLCFLEV-DAELLWKTSA-N 0.000 abstract 2
- 206010055113 Breast cancer metastatic Diseases 0.000 abstract 2
- NKANXQFJJICGDU-QPLCGJKRSA-N Tamoxifen Chemical compound C=1C=CC=CC=1C(/CC)=C(C=1C=CC(OCCN(C)C)=CC=1)/C1=CC=CC=C1 NKANXQFJJICGDU-QPLCGJKRSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229960002087 pertuzumab Drugs 0.000 abstract 2
- 230000004083 survival effect Effects 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 229940122815 Aromatase inhibitor Drugs 0.000 abstract 1
- VWUXBMIQPBEWFH-WCCTWKNTSA-N Fulvestrant Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)CC2=C1 VWUXBMIQPBEWFH-WCCTWKNTSA-N 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 208000003721 Triple Negative Breast Neoplasms Diseases 0.000 abstract 1
- 102000001307 androgen receptors Human genes 0.000 abstract 1
- 108010080146 androgen receptors Proteins 0.000 abstract 1
- 229940087620 aromasin Drugs 0.000 abstract 1
- 239000003886 aromatase inhibitor Substances 0.000 abstract 1
- 229940120638 avastin Drugs 0.000 abstract 1
- 229960000397 bevacizumab Drugs 0.000 abstract 1
- 229960000255 exemestane Drugs 0.000 abstract 1
- 229960002258 fulvestrant Drugs 0.000 abstract 1
- 229940022353 herceptin Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000333 selective estrogen receptor modulator Substances 0.000 abstract 1
- 229940095743 selective estrogen receptor modulator Drugs 0.000 abstract 1
- 229960001603 tamoxifen Drugs 0.000 abstract 1
- 229960005026 toremifene Drugs 0.000 abstract 1
- XFCLJVABOIYOMF-QPLCGJKRSA-N toremifene Chemical compound C1=CC(OCCN(C)C)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 XFCLJVABOIYOMF-QPLCGJKRSA-N 0.000 abstract 1
- 229960000575 trastuzumab Drugs 0.000 abstract 1
- 229960001612 trastuzumab emtansine Drugs 0.000 abstract 1
- 208000022679 triple-negative breast carcinoma Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/02—Carbamic acids; Salts of carbamic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261671366P | 2012-07-13 | 2012-07-13 | |
US201261726274P | 2012-11-14 | 2012-11-14 | |
PCT/US2013/029667 WO2014011220A2 (en) | 2012-07-13 | 2013-03-07 | A method of treating androgen receptor (ar)-positive breast cancers with selective androgen receptor modulator (sarms) |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2015DN01046A true IN2015DN01046A (de) | 2015-06-26 |
Family
ID=49914508
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1046DEN2015 IN2015DN01046A (de) | 2012-07-13 | 2013-03-07 |
Country Status (20)
Country | Link |
---|---|
US (1) | US9604916B2 (de) |
EP (2) | EP3733170A1 (de) |
JP (3) | JP6226978B2 (de) |
KR (2) | KR102238970B1 (de) |
CN (3) | CN110840870A (de) |
AU (3) | AU2013203600C1 (de) |
CA (1) | CA2879049C (de) |
CY (1) | CY1123542T1 (de) |
DK (1) | DK2872482T3 (de) |
ES (1) | ES2818915T3 (de) |
HR (1) | HRP20201463T1 (de) |
HU (1) | HUE052574T2 (de) |
IL (1) | IL236681B (de) |
IN (1) | IN2015DN01046A (de) |
LT (1) | LT2872482T (de) |
MX (2) | MX2015000572A (de) |
PL (1) | PL2872482T3 (de) |
PT (1) | PT2872482T (de) |
RU (2) | RU2648959C2 (de) |
WO (1) | WO2014011220A2 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9884038B2 (en) | 2004-06-07 | 2018-02-06 | University Of Tennessee Research Foundation | Selective androgen receptor modulator and methods of use thereof |
WO2007045027A1 (en) | 2005-10-19 | 2007-04-26 | Chavah Pty Ltd | Reduction of side effects from aromatase inhibitors used for treating breast cancer |
US9844528B2 (en) | 2006-08-24 | 2017-12-19 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
US10010521B2 (en) | 2006-08-24 | 2018-07-03 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
US9730908B2 (en) | 2006-08-24 | 2017-08-15 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
US7968603B2 (en) | 2007-09-11 | 2011-06-28 | University Of Tennessee Research Foundation | Solid forms of selective androgen receptor modulators |
US9622992B2 (en) | 2012-07-13 | 2017-04-18 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
US9969683B2 (en) | 2012-07-13 | 2018-05-15 | Gtx, Inc. | Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS) |
US10314807B2 (en) | 2012-07-13 | 2019-06-11 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
US10987334B2 (en) | 2012-07-13 | 2021-04-27 | University Of Tennessee Research Foundation | Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs) |
US10258596B2 (en) | 2012-07-13 | 2019-04-16 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
US9744149B2 (en) | 2012-07-13 | 2017-08-29 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
EP3733170A1 (de) | 2012-07-13 | 2020-11-04 | Oncternal Therapeutics, Inc. | Verfahren zur behandlung von androgenrezeptor(ar)-positivem brustkrebs mit selektivem androgenrezeptormodulator (sarms) |
JP5958483B2 (ja) * | 2013-07-31 | 2016-08-02 | 株式会社村田製作所 | 電力増幅モジュール |
CN106999453A (zh) * | 2014-10-16 | 2017-08-01 | Gtx公司 | 使用sarm治疗泌尿病症的方法 |
US9351977B2 (en) | 2014-10-22 | 2016-05-31 | Chavah Pty Ltd. | Methods of reducing mammographic breast density and/or breast cancer risk |
US10471023B2 (en) | 2015-03-12 | 2019-11-12 | British Columbia Cancer Agency Branch | Bisphenol ether derivatives and methods for using the same |
EP4197530A1 (de) * | 2015-04-16 | 2023-06-21 | Novartis AG | Ribociclib-tablette |
US10865184B2 (en) | 2015-04-21 | 2020-12-15 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
BR112017022860A2 (pt) | 2015-04-21 | 2018-07-17 | Gtx Inc | ligantes de decompostos receptores de andrógeno seletivos (sard) e métodos de utilização dos mesmos |
US10441570B2 (en) | 2015-04-21 | 2019-10-15 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) Ligands and methods of use thereof |
US10806720B2 (en) | 2015-04-21 | 2020-10-20 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US10093613B2 (en) | 2015-04-21 | 2018-10-09 | Gtx, Inc. | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US10035763B2 (en) | 2015-04-21 | 2018-07-31 | Gtx, Inc. | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US10017471B2 (en) | 2015-04-21 | 2018-07-10 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US10654809B2 (en) | 2016-06-10 | 2020-05-19 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US9834507B2 (en) | 2015-04-21 | 2017-12-05 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US9815776B2 (en) | 2015-04-21 | 2017-11-14 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
SG11201803260PA (en) * | 2015-10-22 | 2018-05-30 | Havah Therapeutics Pty Ltd | Methods of reducing mammographic breast density and/or breast cancer risk |
AU2017242027B2 (en) | 2016-04-01 | 2020-10-08 | Recurium Ip Holdings, Llc | Estrogen receptor modulators |
US20170298033A1 (en) | 2016-04-15 | 2017-10-19 | The University Of British Columbia | Bisphenol derivatives and their use as androgen receptor activity modulators |
CN109310664A (zh) * | 2016-06-10 | 2019-02-05 | 田纳西大学研究基金会 | 选择性雄激素受体降解剂(sard)配体和其使用方法 |
US11230523B2 (en) | 2016-06-10 | 2022-01-25 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US10806719B2 (en) | 2016-06-10 | 2020-10-20 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
NZ759691A (en) * | 2017-06-29 | 2023-05-26 | G1 Therapeutics Inc | Morphic forms of git38 and methods of manufacture thereof |
WO2019226991A1 (en) | 2018-05-25 | 2019-11-28 | Essa Pharma, Inc. | Androgen receptor modulators and methods for their use |
CN109761778A (zh) * | 2018-12-10 | 2019-05-17 | 石家庄市度智医药科技有限公司 | 一种合成光学活性α-羟基丙酰胺衍生物的方法 |
KR20210144827A (ko) * | 2019-03-28 | 2021-11-30 | 에싸 파마 아이엔씨. | 안드로겐 수용체의 억제제를 포함하는 약제학적 조성물 및 조합물 및 그의 용도 |
WO2020205608A1 (en) * | 2019-03-29 | 2020-10-08 | Emory University | Uses of androgen receptor antagonists and jnk pathway inhibitors, and pharmaceutical compositions related thereto |
WO2020243373A1 (en) * | 2019-05-29 | 2020-12-03 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (sard) ligands and methods of use thereof |
AU2020287392A1 (en) | 2019-06-03 | 2021-12-23 | Havah Therapeutics Pty Ltd | Pharmaceutical formulations and systems for delivery of an androgenic agent and an aromatase inhibitor and methods for use |
BR112022002138A2 (pt) | 2019-08-06 | 2022-04-19 | Recurium Ip Holdings Llc | Moduladores do receptor de estrogênio para tratamento de mutantes |
CA3173036A1 (en) * | 2020-02-25 | 2021-09-02 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (sard) ligands and methods of use thereof |
US20210323931A1 (en) | 2020-04-17 | 2021-10-21 | Essa Pharma, Inc. | Solid forms of an n-terminal domain androgen receptor inhibitor and uses thereof |
WO2023101710A1 (en) * | 2021-12-02 | 2023-06-08 | Veru Inc. | Methods of treating breast cancers with selective androgen receptor modulators and additional therapeutic agents |
WO2023172891A2 (en) * | 2022-03-07 | 2023-09-14 | Baylor College Of Medicine | Biomarkers for combination therapy for er+ breast cancer |
WO2023244059A1 (en) * | 2022-06-15 | 2023-12-21 | Ildong Pharmaceutical Co., Ltd. | Methods of treating cancer using dual androgen receptor and pde5 inhibitor compounds |
Family Cites Families (163)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3256096A (en) | 1961-08-11 | 1966-06-14 | Organic Nutrients Inc | Anabolic stimulator as a poultry feed supplement |
US3239345A (en) | 1965-02-15 | 1966-03-08 | Estrogenic compounds and animal growth promoters | |
US3949085A (en) | 1970-05-27 | 1976-04-06 | Chinoin Gyogyszer-Es Vegyeszeti Termakek Gyara Rt | Anabolic-weight-gain promoting compositions containing isoflavone derivatives and method using same |
US4411890A (en) | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
GB1360001A (en) | 1971-06-16 | 1974-07-17 | Scherico Ltd | Pharmaceutical compositions comprising substituted anilides |
US3875229A (en) | 1972-11-24 | 1975-04-01 | Schering Corp | Substituted carboxanilides |
US3865801A (en) | 1973-06-15 | 1975-02-11 | Atomic Energy Commission | Stabilization of urinary erythropoietin using sodium p-aminosalicylate and extracting into phenol |
US3946109A (en) | 1973-08-08 | 1976-03-23 | Ernst Kolb | Animal feed composition containing certain vitamin combinations |
US4036979A (en) | 1974-01-25 | 1977-07-19 | American Cyanamid Company | Compositions containing 4,5,6,7-tetrahydrobenz[b]thien-4-yl-ureas or derivatives and methods of enhancing growth rate |
US4211781A (en) | 1974-09-23 | 1980-07-08 | Pfizer Inc. | Process for the preparation of dustless quinoxaline-1,4-dioxide animal feed supplement premixes |
US3991750A (en) | 1975-04-28 | 1976-11-16 | Syntex Corporation | Dromostanolone propionate implant pellet useful for producing weight gains in animals and suppressing estrus in female animals |
JPS6044294B2 (ja) | 1976-04-15 | 1985-10-02 | 帝国臓器製薬株式会社 | アニリド誘導体 |
US4139638A (en) | 1976-09-23 | 1979-02-13 | Schering Corporation | Methods for the treatment of hirsutism |
EP0002309B1 (de) | 1977-10-12 | 1982-12-01 | Imperial Chemical Industries Plc | Acylanilide, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische und tierärztliche Zusammensetzungen |
US4191775A (en) | 1977-12-15 | 1980-03-04 | Imperial Chemical Industries Limited | Amide derivatives |
US4447421A (en) | 1980-05-08 | 1984-05-08 | American Cyanamid Company | Process for the preparation of medicated animal feed supplement |
NZ197008A (en) | 1980-05-22 | 1984-10-19 | Ici Ltd | Acylanilide derivatives and pharmaceutical compositions |
JPS57171904A (en) | 1981-04-15 | 1982-10-22 | Mitsubishi Petrochem Co Ltd | Tri- or tetra-substituted phenoxycarboxylic acid anilide type herbicide |
ATE28864T1 (de) | 1982-07-23 | 1987-08-15 | Ici Plc | Amide-derivate. |
NZ210501A (en) | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
KR850004274A (ko) | 1983-12-13 | 1985-07-11 | 원본미기재 | 에리트로포이에틴의 제조방법 |
FR2576025B1 (fr) | 1985-01-14 | 1987-01-23 | Roussel Uclaf | Nouveaux steroides substitues en position 10, leur procede et les intermediaires de preparation, leur application comme medicaments, les compositions pharmaceutiques les contenant |
US4670249A (en) | 1985-04-12 | 1987-06-02 | International Minerals & Chemical Corp. | Growth-promoting compositions |
US4837004A (en) | 1985-10-18 | 1989-06-06 | Eastman Kodak Company | Rumen-stable pellets |
US4904473A (en) | 1986-06-23 | 1990-02-27 | International Minerals & Chemical Corp. | Ruminant feed antacid containing potassium, sodium and chlorine |
GB8617653D0 (en) | 1986-07-18 | 1986-08-28 | Ici Plc | Amide derivatives |
GB8617652D0 (en) | 1986-07-18 | 1986-08-28 | Ici Plc | Acylanilide derivatives |
US4849447A (en) | 1987-10-13 | 1989-07-18 | Pitman-Moore, Inc. | Zearalanol derivatives with anabolic activity |
ATE113607T1 (de) | 1988-01-28 | 1994-11-15 | Polygen Holding Corp | Polypeptidverbindungen mit wachstumshormonfreisetzender aktivität. |
WO1989007110A1 (en) | 1988-01-28 | 1989-08-10 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
US4977288A (en) | 1988-01-29 | 1990-12-11 | President And Fellows Of Harvard College | M-aminophenyltrialkylstannane |
US5162504A (en) | 1988-06-03 | 1992-11-10 | Cytogen Corporation | Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients |
US5179080A (en) | 1989-08-31 | 1993-01-12 | Clinical Homecare, Corp. | Formulations containing growth hormone and nutritional supplements, and methods of treating malnutrition in chronic lung disease |
WO1991005867A1 (en) | 1989-10-13 | 1991-05-02 | Amgen Inc. | Erythropoietin isoforms |
US5030657A (en) | 1989-10-23 | 1991-07-09 | University Of Georgia Research Foundation, Inc. | L-carnitine supplemented catfish diet |
US5288496A (en) | 1990-05-15 | 1994-02-22 | Stolle Research & Development Corporation | Growth promoters for animals |
US5663146A (en) | 1991-08-22 | 1997-09-02 | Administrators Of The Tulane Educational Fund | Polypeptide analogues having growth hormone releasing activity |
EP0748220A4 (de) | 1994-01-21 | 1997-09-10 | Sepracor Inc | Verfahren und zusammensetzungen zur behandlung von androgen-abhängigen krankheiten unter verwenddung von optisch reinem r-(-)casodex |
US5609849A (en) | 1994-03-11 | 1997-03-11 | The Trustees Of The University Of Pennsylvania | Serotonin (5-HT1A) receptor ligands and imaging agents |
CA2149496C (en) | 1994-05-19 | 2006-12-19 | Ronald Gebhard | 11,21-bisphenyl-19-norpregnane derivatives |
US5612359A (en) | 1994-08-26 | 1997-03-18 | Bristol-Myers Squibb Company | Substituted biphenyl isoxazole sulfonamides |
US5656651A (en) | 1995-06-16 | 1997-08-12 | Biophysica Inc. | Androgenic directed compositions |
WO1998005962A1 (en) | 1996-08-02 | 1998-02-12 | Panvera Corporation | A method for quantitating competitive binding of molecules to proteins utilizing fluorescence polarization |
US6071957A (en) | 1996-11-27 | 2000-06-06 | The University Of Tennessee Research Corporation | Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer |
US7759520B2 (en) | 1996-11-27 | 2010-07-20 | University Of Tennessee Research Foundation | Synthesis of selective androgen receptor modulators |
US7518013B2 (en) | 2000-08-24 | 2009-04-14 | University Of Tennessee Research Foundation | Selective androgen receptor modulators |
US20050038110A1 (en) | 2000-08-24 | 2005-02-17 | Steiner Mitchell S. | Selective androgen receptor modulators and methods of use thereof |
US6492554B2 (en) | 2000-08-24 | 2002-12-10 | The University Of Tennessee Research Corporation | Selective androgen receptor modulators and methods of use thereof |
US6995284B2 (en) | 2000-08-24 | 2006-02-07 | The University Of Tennessee Research Foundation | Synthesis of selective androgen receptor modulators |
US7205437B2 (en) | 1996-11-27 | 2007-04-17 | University Of Tennessee Research Foundation | Selective androgen receptor modulators |
US20090264534A1 (en) | 1996-11-27 | 2009-10-22 | Dalton James T | Selective androgen receptor modulators |
US5929058A (en) | 1996-12-24 | 1999-07-27 | Zymogenetics, Inc. | Treatment agents and methods for treating type II diabetes and symptoms of type II diabetes |
TW536540B (en) | 1997-01-30 | 2003-06-11 | Bristol Myers Squibb Co | Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe |
WO1998053826A1 (en) | 1997-05-30 | 1998-12-03 | The University Of Tennessee Research Corporation | Non-steroidal agonist compounds and their use in male hormone therapy |
US6019957A (en) | 1997-06-04 | 2000-02-01 | The University Of Tennessee Research Corporation | Non-steroidal radiolabeled agonist/antagonist compounds and their use in prostate cancer imaging |
EP0903146A1 (de) | 1997-09-23 | 1999-03-24 | Applied Research Systems ARS Holdings N.V. | 21-Hydroy-6,19-oxidoprogesterone (21-0H-60P) als ANitoglucocortikoid |
US6022137A (en) | 1998-04-29 | 2000-02-08 | Buckeye Feed Mills, Inc. | Conditioner for processing raw grain composition to produce pelletized feed |
DE69940063D1 (de) | 1998-07-06 | 2009-01-22 | Bristol Myers Squibb Co | Biphenylsulfonamide als zweifach aktive rezeptor antagonisten von angiotensin und endothelin |
DK1140184T3 (da) | 1998-12-23 | 2003-09-29 | Searle Llc | Kombinationer af cholesterylestertransferproteinhæmmere og nikotinsyrederivater til hjertekar indikationer |
ES2226811T3 (es) | 1999-03-29 | 2005-04-01 | F. Hoffmann-La Roche Ag | Activadores de glucoquinasa. |
US6548529B1 (en) | 1999-04-05 | 2003-04-15 | Bristol-Myers Squibb Company | Heterocyclic containing biphenyl aP2 inhibitors and method |
WO2001027086A1 (fr) | 1999-10-14 | 2001-04-19 | Kaken Pharmaceutical Co., Ltd. | Derives de tetrahydroquinoline |
AU775928B2 (en) | 1999-10-14 | 2004-08-19 | Bristol-Myers Squibb Company | Crystallographic structure of the androgen receptor ligand binding domain |
NZ518392A (en) | 1999-10-19 | 2004-02-27 | Nobex Corp | Methods of asymmetrically synthesizing enantiomers of casodex, its derivatives and intermediates thereof |
CN1413188A (zh) | 1999-10-27 | 2003-04-23 | 诺贝克斯公司 | 基本纯的比卡鲁胺合成中中间体的拆分 |
US6353111B1 (en) | 1999-12-15 | 2002-03-05 | Hoffmann-La Roche Inc. | Trans olefinic glucokinase activators |
WO2001049709A1 (en) | 2000-01-03 | 2001-07-12 | Ramot University Authority For Applied Research & Industrial Development Ltd. | Glycogen synthase kinase-3 inhibitors |
US6441197B1 (en) | 2000-01-20 | 2002-08-27 | Daiichi Pure Chemicals Co., Ltd. | Diaminofluorescein derivative |
US6395767B2 (en) | 2000-03-10 | 2002-05-28 | Bristol-Myers Squibb Company | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method |
US7713989B2 (en) | 2000-04-27 | 2010-05-11 | Dow Robert L | Glucocorticoid receptor modulators |
AU2001288213B2 (en) | 2000-06-28 | 2005-04-14 | Bristol-Myers Squibb Company | Selective androgen receptor modulators and methods for their identification, design and use |
US6998500B2 (en) | 2000-08-24 | 2006-02-14 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
US8445534B2 (en) | 2000-08-24 | 2013-05-21 | University Of Tennessee Research Foundation | Treating androgen decline in aging male (ADAM)-associated conditions with SARMs |
US20070173546A1 (en) | 2000-08-24 | 2007-07-26 | Dalton James T | Selective androgen receptor modulators and method of use thereof |
US7645898B2 (en) | 2000-08-24 | 2010-01-12 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and method of use thereof |
US7026500B2 (en) | 2000-08-24 | 2006-04-11 | University Of Tennessee Research Foundation | Halogenated selective androgen receptor modulators and methods of use thereof |
US20020173495A1 (en) | 2000-08-24 | 2002-11-21 | Dalton James T. | Selective androgen receptor modulators and methods of use thereof |
US20040260108A1 (en) | 2001-06-25 | 2004-12-23 | Dalton James T. | Metabolites of selective androgen receptor modulators and methods of use thereof |
US8008348B2 (en) | 2001-12-06 | 2011-08-30 | University Of Tennessee Research Foundation | Treating muscle wasting with selective androgen receptor modulators |
US6838484B2 (en) | 2000-08-24 | 2005-01-04 | University Of Tennessee Research Foundation | Formulations comprising selective androgen receptor modulators |
US20030232792A1 (en) | 2000-08-24 | 2003-12-18 | Dalton James T. | Selective androgen receptor modulators and methods of use thereof |
ES2321933T3 (es) | 2000-08-24 | 2009-06-15 | University Of Tennessee Research Foundation | Moduladores selectivos del receptor de androgeno y metodos de uso de los mismos. |
US7919647B2 (en) | 2000-08-24 | 2011-04-05 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
US7622503B2 (en) | 2000-08-24 | 2009-11-24 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
US7855229B2 (en) | 2000-08-24 | 2010-12-21 | University Of Tennessee Research Foundation | Treating wasting disorders with selective androgen receptor modulators |
US20030229099A1 (en) | 2000-08-30 | 2003-12-11 | Zhu Hugh Y. | Novel farnesyl protein transferase inhibitors as antitumor agents |
US6777446B2 (en) | 2000-09-05 | 2004-08-17 | Tularik, Inc. | FXR modulators |
AU2001286243A1 (en) | 2000-09-14 | 2002-03-26 | Kaken Pharmaceutical Co., Ltd. | Tetrahydroquinoline compounds |
SE0102300D0 (sv) | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
SE0102299D0 (sv) | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
US6645974B2 (en) | 2001-07-31 | 2003-11-11 | Merck & Co., Inc. | Androgen receptor modulators and methods for use thereof |
JP2003137814A (ja) | 2001-08-10 | 2003-05-14 | Takeda Chem Ind Ltd | GnRHアゴニストの併用剤 |
SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
US20060004042A1 (en) | 2001-08-23 | 2006-01-05 | Dalton James T | Formulations comprising selective androgen receptor modulators |
AU2002356928B2 (en) | 2001-11-29 | 2008-04-17 | Gtx Inc. | Prevention and treatment of androgen-deprivation induced osteoporosis |
US20070161608A1 (en) | 2001-12-06 | 2007-07-12 | Dalton James T | Selective androgen receptor modulators for treating muscle wasting |
US20070066568A1 (en) | 2005-08-31 | 2007-03-22 | Dalton James T | Treating renal disease, burns, wounds and spinal cord injury with selective androgen receptor modulators |
JP4605557B2 (ja) | 2001-12-06 | 2011-01-05 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | 選択的アンドロゲンレセプタ修飾因子を用いた筋萎縮治療 |
US8853266B2 (en) | 2001-12-06 | 2014-10-07 | University Of Tennessee Research Foundation | Selective androgen receptor modulators for treating diabetes |
EP1474139B1 (de) | 2002-02-01 | 2007-11-21 | Merck & Co., Inc. | 11-beta-hydroxysteroid-dehydrogenase-1-hemmer zur behandlung von diabetes, adipositas und dyslipidämie |
MXPA04007639A (es) | 2002-02-07 | 2005-07-13 | Gtx Inc | Tratamiento de hiperplasia benigna de la prostata con un modulador de receptor de androgeno selectivo (sarm). |
US7803970B2 (en) | 2002-02-28 | 2010-09-28 | University Of Tennessee Research Foundation | Multi-substitued selective androgen receptor modulators and methods of use thereof |
WO2003074449A2 (en) | 2002-02-28 | 2003-09-12 | University Of Tennessee Research Foundation | Multi-substitued selective androgen receptor modulators and methods of use thereof |
US7344700B2 (en) | 2002-02-28 | 2008-03-18 | University Of Tennessee Research Corporation | Radiolabeled selective androgen receptor modulators and their use in prostate cancer imaging and therapy |
JP2006506318A (ja) | 2002-02-28 | 2006-02-23 | ユニバーシティ・オブ・テネシー・リサーチ・ファウンデーション | ハロアセトアミド若しくはアジ化物置換化合物及びその使用方法 |
ES2528764T3 (es) | 2002-02-28 | 2015-02-12 | University Of Tennessee Research Foundation | Moduladores selectivos multisustituidos del receptor de andrógeno y métodos de uso de los mismos |
US7772433B2 (en) | 2002-02-28 | 2010-08-10 | University Of Tennessee Research Foundation | SARMS and method of use thereof |
JP4516316B2 (ja) | 2002-03-13 | 2010-08-04 | メルク・シャープ・エンド・ドーム・コーポレイション | アンドロゲン受容体モジュレーターとしてのフッ化4−アザステロイド誘導体 |
AR040241A1 (es) | 2002-06-10 | 2005-03-23 | Merck & Co Inc | Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia |
GEP20074191B (en) | 2002-06-17 | 2007-09-10 | Univ Tennessee Res Foundation | N-bridged selective androgen receptor modulators and methods of use thereof |
EP1398029A1 (de) | 2002-09-10 | 2004-03-17 | LION Bioscience AG | 3-substituierte Pyrazol-Derivate,die an den NR3B1 Rezeptor binden |
US20040197928A1 (en) | 2002-10-15 | 2004-10-07 | Dalton James T. | Method for detecting selective androgen receptor modulators |
AU2003287077B2 (en) | 2002-10-15 | 2007-09-20 | University Of Tennessee Research Foundation | Methylene-bridged selective androgen receptor modulators and methods of use thereof |
US20040265916A1 (en) | 2002-10-15 | 2004-12-30 | Dalton James T. | Method for detecting selective androgen receptor modulators |
AU2003287076C1 (en) | 2002-10-15 | 2010-03-04 | University Of Tennessee Research Foundation | Heterocyclic selective androgen receptor modulators and methods of use thereof |
AU2003287075A1 (en) | 2002-10-15 | 2004-05-04 | Gtx, Inc. | Treating obesity with selective androgen receptor modulators |
US20040087810A1 (en) | 2002-10-23 | 2004-05-06 | Dalton James T. | Irreversible selective androgen receptor modulators and methods of use thereof |
US20140011774A1 (en) | 2002-12-05 | 2014-01-09 | University Of Tennessee Research Foundation | Selective androgen receptor modulators |
US8309603B2 (en) | 2004-06-07 | 2012-11-13 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
AU2003300012A1 (en) | 2002-12-30 | 2004-07-29 | Indiana University Research & Technology Corporation | Method of treatment for central nervous system injury |
WO2004062612A2 (en) | 2003-01-13 | 2004-07-29 | Gtx Inc. | Large-scale synthesis of selective androgen receptor modulators |
JP2006516286A (ja) * | 2003-01-22 | 2006-06-29 | ジーティーエックス・インコーポレイテッド | Sarmによる女性のアンドロゲン減少に関連する病気の治療 |
CA2513975A1 (en) | 2003-01-22 | 2004-08-12 | Gtx Inc. | A method of treating breast cancer with androgen receptor antagonists |
US20040167103A1 (en) * | 2003-02-24 | 2004-08-26 | Dalton James T. | Haloacetamide and azide substituted compounds and methods of use thereof |
GB0308335D0 (en) | 2003-04-10 | 2003-05-14 | Novartis Ag | Organic compounds |
CN1325506C (zh) | 2003-05-15 | 2007-07-11 | 中国科学院上海药物研究所 | 骨重吸收抑制剂阿伦膦酸及生理可接受的盐和它的制备 |
WO2005000266A2 (en) | 2003-05-22 | 2005-01-06 | Neopharm, Inc. | Liposomal formulations comprising a combination of two or more active agents |
FI20030958A0 (fi) | 2003-06-27 | 2003-06-27 | Orion Corp | Uusia yhdisteitä |
AU2004272004B2 (en) | 2003-09-10 | 2009-01-22 | Merck Sharp & Dohme Corp. | 17-heterocyclic-4-azasteroid derivatives as androgen receptor modulators |
SI1696909T1 (sl) | 2003-09-12 | 2008-02-29 | Serono Lab | Derivati benzotiazola za zdravljenje diabetesa |
AU2004281708B2 (en) | 2003-10-14 | 2011-02-17 | University Of Tennessee Research Foundation | Treating bone-related disorders with selective androgen receptor modulators |
TW200523235A (en) * | 2003-10-15 | 2005-07-16 | Gtx Inc | Anti-cancer compounds and methods of use thereof |
US20050137172A1 (en) | 2003-10-15 | 2005-06-23 | Dalton James T. | Haloacetamide and azide substituted compounds and methods of use thereof |
GB0325402D0 (en) | 2003-10-31 | 2003-12-03 | Astrazeneca Ab | Compounds |
EA200501761A1 (ru) | 2003-12-16 | 2006-04-28 | Джи Ти Икс, ИНК. | Пролекарственные формы селективных модуляторов андрогеновых рецепторов и способы их применения |
TW200530181A (en) | 2004-01-13 | 2005-09-16 | Bristol Myers Squibb Co | Heterocyclic compounds useful as growth hormone secretagogues |
ES2329489T3 (es) | 2004-05-03 | 2009-11-26 | F. Hoffmann-La Roche Ag | Derivados de indolilo como moduladores del receptor x del higado. |
US20110237664A1 (en) * | 2004-06-07 | 2011-09-29 | Dalton James T | Selective androgen receptor modulators for treating diabetes |
DK2289872T3 (en) | 2004-06-07 | 2017-10-09 | Univ Tennessee Res Found | Medical use of a selective androgen receptor modulator |
US20130034562A1 (en) | 2004-06-07 | 2013-02-07 | Dalton James T | Selective androgen receptor modulators for treating diabetes |
CA2573761A1 (en) | 2004-07-14 | 2006-02-23 | Janssen Pharmaceutica N.V. | Use of estrogen related receptor-modulating aryl ethers |
US7825229B2 (en) | 2005-03-25 | 2010-11-02 | Rosetta Genomics Ltd. | Lung cancer-related nucleic acids |
EP1951706A1 (de) | 2005-11-01 | 2008-08-06 | Janssen Pharmaceutica N.V. | Dihydroisoindolone als allosterische modulatoren von glucokinase |
EP1960385A1 (de) | 2005-11-01 | 2008-08-27 | Janssen Pharmaceutica N.V. | Substituierte dihydroisoindolone als allostere modulatoren von glucokinase |
AU2006318400C1 (en) | 2005-11-28 | 2013-01-17 | Gtx, Inc. | Nuclear receptor binding agents |
US8158828B2 (en) | 2005-11-28 | 2012-04-17 | Gtx, Inc. | Nuclear receptor binding agents |
US20070161578A1 (en) | 2005-12-21 | 2007-07-12 | Hwa Joyce J | Treatment of nonalcoholic fatty liver disease using cholesterol lowering agents and/or H3 receptor antagonist/inverse agonist |
EP1801140A1 (de) | 2005-12-22 | 2007-06-27 | Mnemoscience GmbH | Macrodiacrylat |
US8168216B2 (en) * | 2006-03-22 | 2012-05-01 | Medigene Ag | Treatment of triple receptor negative breast cancer |
EP2038252B1 (de) * | 2006-07-12 | 2016-11-02 | University of Tennessee Research Foundation | Substituierte acylanilide und verfahren zu ihrer verwendung |
WO2008024456A2 (en) | 2006-08-24 | 2008-02-28 | University Of Tennessee Research Foundation | Substituted acylanilides and methods of use thereof |
EP2647376A1 (de) | 2007-01-22 | 2013-10-09 | Gtx, Inc. | Nuklearrezeptorbindende Wirkstoffe |
US9623021B2 (en) | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
PL2205552T3 (pl) | 2007-09-11 | 2018-07-31 | Gtx, Inc. | Krystaliczny polimorf selektywnych modulatorów receptora androgenowego (R) lub (S)-N-(4-cyjano-3-(trifluorometylo)fenylo)-3-(4-cyjanofenoksy)-2-hydroksy-2-metylopropanamidu |
US7968603B2 (en) | 2007-09-11 | 2011-06-28 | University Of Tennessee Research Foundation | Solid forms of selective androgen receptor modulators |
WO2009155481A1 (en) | 2008-06-20 | 2009-12-23 | Gtx, Inc. | Metabolites of selective androgen receptor modulators and methods of use thereof |
EP2486149B1 (de) * | 2009-08-06 | 2015-06-17 | John Wayne Cancer Institute | Diagnose von primärem und metastasierendem basal-like brustkrebs und anderen krebstypen |
EA201290208A1 (ru) | 2009-10-23 | 2012-10-30 | Хелт Рисерч Инк. | Способ лечения андроген-рецептор позитивных раковых заболеваний |
JP2013516501A (ja) | 2010-01-11 | 2013-05-13 | ジーティーエックス・インコーポレイテッド | マイボーム腺機能障害を治療する方法 |
UY33740A (es) * | 2010-11-18 | 2012-05-31 | Takeda Pharmaceutical | Método para tratar el cáncer de mama y cáncer de ovarios |
EP3733170A1 (de) | 2012-07-13 | 2020-11-04 | Oncternal Therapeutics, Inc. | Verfahren zur behandlung von androgenrezeptor(ar)-positivem brustkrebs mit selektivem androgenrezeptormodulator (sarms) |
US9969683B2 (en) | 2012-07-13 | 2018-05-15 | Gtx, Inc. | Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS) |
US9622992B2 (en) | 2012-07-13 | 2017-04-18 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
-
2013
- 2013-03-07 EP EP20179413.8A patent/EP3733170A1/de active Pending
- 2013-03-07 CN CN201911188725.7A patent/CN110840870A/zh active Pending
- 2013-03-07 KR KR1020207016499A patent/KR102238970B1/ko active IP Right Grant
- 2013-03-07 CN CN201380040703.0A patent/CN104754939A/zh active Pending
- 2013-03-07 CA CA2879049A patent/CA2879049C/en active Active
- 2013-03-07 EP EP13817231.7A patent/EP2872482B1/de active Active
- 2013-03-07 RU RU2015104780A patent/RU2648959C2/ru active
- 2013-03-07 PT PT138172317T patent/PT2872482T/pt unknown
- 2013-03-07 US US13/789,005 patent/US9604916B2/en active Active
- 2013-03-07 HU HUE13817231A patent/HUE052574T2/hu unknown
- 2013-03-07 ES ES13817231T patent/ES2818915T3/es active Active
- 2013-03-07 PL PL13817231T patent/PL2872482T3/pl unknown
- 2013-03-07 RU RU2017141776A patent/RU2717835C2/ru active
- 2013-03-07 DK DK13817231.7T patent/DK2872482T3/da active
- 2013-03-07 WO PCT/US2013/029667 patent/WO2014011220A2/en active Application Filing
- 2013-03-07 CN CN201711417639.XA patent/CN108143728A/zh active Pending
- 2013-03-07 IN IN1046DEN2015 patent/IN2015DN01046A/en unknown
- 2013-03-07 KR KR1020157003951A patent/KR102122941B1/ko active IP Right Grant
- 2013-03-07 AU AU2013203600A patent/AU2013203600C1/en active Active
- 2013-03-07 JP JP2015521597A patent/JP6226978B2/ja active Active
- 2013-03-07 LT LTEP13817231.7T patent/LT2872482T/lt unknown
- 2013-03-07 MX MX2015000572A patent/MX2015000572A/es active IP Right Grant
-
2015
- 2015-01-12 IL IL236681A patent/IL236681B/en active IP Right Grant
- 2015-01-13 MX MX2020009725A patent/MX2020009725A/es unknown
-
2016
- 2016-06-03 AU AU2016203696A patent/AU2016203696B2/en active Active
-
2017
- 2017-03-13 JP JP2017046924A patent/JP6386120B2/ja active Active
-
2018
- 2018-02-28 AU AU2018201450A patent/AU2018201450B2/en active Active
- 2018-08-08 JP JP2018149623A patent/JP6759290B2/ja active Active
-
2020
- 2020-09-09 CY CY20201100853T patent/CY1123542T1/el unknown
- 2020-09-14 HR HRP20201463TT patent/HRP20201463T1/hr unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2015DN01046A (de) | ||
MX2019008208A (es) | Métodos para tratar el cáncer con anticuerpos anti-tim-3. | |
MX2018006477A (es) | Anticuerpos y metodos de uso de estos. | |
SG194701A1 (en) | Anti-cd40 antibodies and methods of use | |
MX2022010623A (es) | Terapias de combinacion que comprenden un receptor quimerico de antigeno cd19 para el cancer. | |
NZ707086A (en) | Anti-cd40 antibodies and methods of use | |
MX2016001901A (es) | Biomarcadores para tratamiento de trastornos neoplasicos usando terapias dirigidas con andrógeno. | |
HK1213925A1 (zh) | 用於治療癌症的涉及抗密蛋白 抗體的組合療法 | |
TW201613887A (en) | Antiproliferative compounds and methods of use thereof | |
MX2017004526A (es) | Terapia combinada de anticuerpos biespecificos especificos para fap y dr5 y agentes quimioterapeuticos. | |
PH12019500261A1 (en) | Methods for treating osteogenesis imperfecta | |
LT2766040T (lt) | Pertuzumabas, trastuzumabas, docetakselis ir karboplatina, skirti ankstyvos stadijos krūties vėžiui gydyti | |
MX368508B (es) | Benralizumab para usarse en la reducción de la tasa de exacerbación de asma. | |
MX2019001977A (es) | Metodos y composiciones para tratar esclerosis multiple y trastornos relacionados. | |
MX2013009732A (es) | Terapias de combinacion comprendiendo agentes anti-erbb3. | |
AR086390A1 (es) | Metodo para el tratamiento de malignidades solidas que incluyen malignidades solidas avanzadas o metastasicas | |
MX2017000886A (es) | Tratamiento con cis-clomifeno de sofocos y perdida osea inducidos por privacion de androgeno terapeutica. | |
MX2017011237A (es) | Alteracion del metabolismo de esteroides para el tratamiento de enfermedades dependientes de esteroides. | |
RS63738B1 (sr) | Kombinovana terapija koja uključuje antitela protiv klaudina 18.2 za lečenje kancera | |
MA40363A (fr) | Agents de liaison de rspo1 et leurs utilisations | |
IN2014CN02671A (de) | ||
UA85798U (ru) | Способ лечения йодозависимых заболеваний щитовидной железы | |
TN2013000114A1 (en) | Methods and compositions for treating lung cancer | |
NZ745950A (en) | Methods and compositions for treating multiple sclerosis and related disorders | |
UA70225U (ru) | Применение композиции, содержащей мирамистин, в качестве лекарственного средства для лечения заболеваний горла |