SI1696909T1 - Derivati benzotiazola za zdravljenje diabetesa - Google Patents
Derivati benzotiazola za zdravljenje diabetesaInfo
- Publication number
- SI1696909T1 SI1696909T1 SI200430550T SI200430550T SI1696909T1 SI 1696909 T1 SI1696909 T1 SI 1696909T1 SI 200430550 T SI200430550 T SI 200430550T SI 200430550 T SI200430550 T SI 200430550T SI 1696909 T1 SI1696909 T1 SI 1696909T1
- Authority
- SI
- Slovenia
- Prior art keywords
- unsubstituted
- substituted
- treatment
- benzothiazole derivatives
- group
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03102740 | 2003-09-12 | ||
PCT/EP2004/052090 WO2005025567A1 (en) | 2003-09-12 | 2004-09-08 | Benzothiazole derivatives for the treatment of diabetes |
EP04787110A EP1696909B1 (en) | 2003-09-12 | 2004-09-08 | Benzothiazole derivatives for the treatment of diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1696909T1 true SI1696909T1 (sl) | 2008-02-29 |
Family
ID=34306921
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200430550T SI1696909T1 (sl) | 2003-09-12 | 2004-09-08 | Derivati benzotiazola za zdravljenje diabetesa |
Country Status (18)
Country | Link |
---|---|
US (2) | US20070088017A1 (sl) |
EP (1) | EP1696909B1 (sl) |
JP (1) | JP5021307B2 (sl) |
AT (1) | ATE378047T1 (sl) |
AU (1) | AU2004271740B2 (sl) |
CA (1) | CA2534314C (sl) |
CY (1) | CY1107820T1 (sl) |
DE (1) | DE602004010178T2 (sl) |
DK (1) | DK1696909T3 (sl) |
ES (1) | ES2297494T3 (sl) |
HK (1) | HK1096594A1 (sl) |
HR (1) | HRP20070527T3 (sl) |
IL (1) | IL174250A (sl) |
NO (1) | NO20061600L (sl) |
PL (1) | PL1696909T3 (sl) |
PT (1) | PT1696909E (sl) |
SI (1) | SI1696909T1 (sl) |
WO (1) | WO2005025567A1 (sl) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7838522B2 (en) * | 2004-11-17 | 2010-11-23 | Ares Trading S.A. | Benzothiazole formulations and use thereof |
BRPI0613042A2 (pt) | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 jnk 억제제 |
EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス,インコーポレイティド | Pde阻害による神経新生の調節 |
EP1942879A1 (en) | 2005-10-31 | 2008-07-16 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
JP5345534B2 (ja) | 2006-08-24 | 2013-11-20 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | 置換アシルアニリドおよびそれらの使用方法 |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
EP2137173A2 (en) * | 2007-04-17 | 2009-12-30 | Laboratoires Serono SA | Process for the preparation of piperazine benzothiazoles |
UA100527C2 (en) * | 2007-10-10 | 2013-01-10 | Астразенека Аб | Benzothiazoles as ghrelin receptor modulators |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
US9604916B2 (en) | 2012-07-13 | 2017-03-28 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
US9969683B2 (en) | 2012-07-13 | 2018-05-15 | Gtx, Inc. | Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS) |
US10987334B2 (en) | 2012-07-13 | 2021-04-27 | University Of Tennessee Research Foundation | Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs) |
US10258596B2 (en) | 2012-07-13 | 2019-04-16 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
US9744149B2 (en) | 2012-07-13 | 2017-08-29 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
US10314807B2 (en) | 2012-07-13 | 2019-06-11 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
US9622992B2 (en) | 2012-07-13 | 2017-04-18 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
WO2014114186A1 (zh) * | 2013-01-24 | 2014-07-31 | 山东亨利医药科技有限责任公司 | Jnk抑制剂 |
WO2017025980A2 (en) * | 2015-08-12 | 2017-02-16 | Shoolineuniversity Of Biotechnology And Management Sciences | Novel benzothiazole derivatives with enhanced biological activity |
US11970467B1 (en) | 2023-10-13 | 2024-04-30 | King Faisal University | N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as an antimicrobial compound |
US11905260B1 (en) | 2023-10-13 | 2024-02-20 | King Faisal University | N′-(1-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as an antimicrobial compound |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1176269A (en) * | 1981-03-02 | 1984-10-16 | Kazimir Sestanj | N-naphthoylglycine derivatives |
US4927831A (en) * | 1988-10-20 | 1990-05-22 | American Home Products | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
US6559188B1 (en) * | 1999-09-17 | 2003-05-06 | Novartis Ag | Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes |
EP1110957A1 (en) * | 1999-12-24 | 2001-06-27 | Applied Research Systems ARS Holding N.V. | Benzazole derivatives and their use as JNK modulators |
JP4589002B2 (ja) * | 2001-12-07 | 2010-12-01 | メルク セローノ ソシエテ アノニム | 強皮症の治療のためのベンザゾール誘導体 |
JP4523289B2 (ja) * | 2002-04-25 | 2010-08-11 | メルク セローノ ソシエテ アノニム | 脳虚血障害又はcns障害の処置のための薬剤としてのピペラジンベンゾチアゾール |
-
2004
- 2004-09-08 DE DE602004010178T patent/DE602004010178T2/de active Active
- 2004-09-08 PL PL04787110T patent/PL1696909T3/pl unknown
- 2004-09-08 ES ES04787110T patent/ES2297494T3/es active Active
- 2004-09-08 AU AU2004271740A patent/AU2004271740B2/en not_active Ceased
- 2004-09-08 JP JP2006525827A patent/JP5021307B2/ja not_active Expired - Fee Related
- 2004-09-08 DK DK04787110T patent/DK1696909T3/da active
- 2004-09-08 AT AT04787110T patent/ATE378047T1/de active
- 2004-09-08 SI SI200430550T patent/SI1696909T1/sl unknown
- 2004-09-08 PT PT04787110T patent/PT1696909E/pt unknown
- 2004-09-08 CA CA2534314A patent/CA2534314C/en not_active Expired - Fee Related
- 2004-09-08 WO PCT/EP2004/052090 patent/WO2005025567A1/en active IP Right Grant
- 2004-09-08 EP EP04787110A patent/EP1696909B1/en active Active
- 2004-09-08 US US10/571,291 patent/US20070088017A1/en not_active Abandoned
-
2006
- 2006-03-12 IL IL174250A patent/IL174250A/en not_active IP Right Cessation
- 2006-04-07 NO NO20061600A patent/NO20061600L/no not_active Application Discontinuation
-
2007
- 2007-02-28 HK HK07102247A patent/HK1096594A1/xx not_active IP Right Cessation
- 2007-11-16 HR HR20070527T patent/HRP20070527T3/xx unknown
- 2007-12-04 CY CY20071101543T patent/CY1107820T1/el unknown
-
2013
- 2013-10-08 US US14/048,690 patent/US20140107116A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE378047T1 (de) | 2007-11-15 |
AU2004271740A1 (en) | 2005-03-24 |
DE602004010178T2 (de) | 2008-09-11 |
US20140107116A1 (en) | 2014-04-17 |
DE602004010178D1 (de) | 2007-12-27 |
US20070088017A1 (en) | 2007-04-19 |
NO20061600L (no) | 2006-04-07 |
EP1696909B1 (en) | 2007-11-14 |
IL174250A (en) | 2011-01-31 |
IL174250A0 (en) | 2006-08-01 |
HRP20070527T3 (en) | 2007-12-31 |
DK1696909T3 (da) | 2008-01-02 |
CA2534314C (en) | 2012-11-13 |
AU2004271740B2 (en) | 2010-10-28 |
PL1696909T3 (pl) | 2008-04-30 |
CA2534314A1 (en) | 2005-03-24 |
EP1696909A1 (en) | 2006-09-06 |
PT1696909E (pt) | 2007-12-21 |
JP2007505083A (ja) | 2007-03-08 |
HK1096594A1 (en) | 2007-06-08 |
CY1107820T1 (el) | 2013-06-19 |
JP5021307B2 (ja) | 2012-09-05 |
ES2297494T3 (es) | 2008-05-01 |
WO2005025567A1 (en) | 2005-03-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1096594A1 (en) | Benzothiazole derivatives for the treatment of diabetes | |
NO20061614L (no) | Benzimidazolacetonitriler | |
ATE557030T1 (de) | Kondensiertes heterocyclisches derivat, dieses enthaltende medizinische zusammensetzung und deren medizinische verwendung | |
NO20080789L (no) | 1,4-benzotiazepin 1,1-dioksidderivater, fremgangsmate for fremstilling derav, medikamenter inneholdende denne forbindelsen og anvendelse derav som et hypolipid | |
NO20051209L (no) | Pyrazolderivater, medisinske sammensetninger inneholdende slike, medisinsk anvendelse derav samt intermediater for samme | |
BRPI0406761A (pt) | Derivados de arila e heteroarila 1,2,3-trissubstituìdos como moduladores do metabolismo e a profilaxia e tratamento de distúrbios relacionados a estes tais como diabetes e hiper-glicemia | |
EA200601869A1 (ru) | Карбоновые кислоты | |
NO20083026L (no) | Terapeutisk middel for diabetes | |
BRPI0412997A (pt) | derivados de dióxido de tiazol-benzoisotiazol substituìdos, método para produzir os mesmos e seu uso | |
MXPA05009356A (es) | Derivados de c-glicosido y sales de los mismos. | |
NO20080728L (no) | Nye 1,4-benzotiazepin-1,1-dioksidderivater som har forbedrede egenskaper, fremgangsmate for fremstilling derav, medikamenter inneholdende nevnte forbindelsene og anvendelse derav | |
NO20065926L (no) | Substituerte oksazolbenzoisotiazoldioksidderivater samt fremgangsmate for fremstilling og anvendelse derav | |
WO2010045303A3 (en) | Pyrrolidine, piperidine and piperazine derivatives and methods of use thereof | |
PA8566201A1 (es) | Nuevos derivados de piridina y quinolina | |
NO20085067L (no) | 4,5-difenyl-pyrimidinyl substituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter | |
NO20061599L (no) | Benzoksazol acetonitriler | |
MA28339A1 (fr) | Derives de l'acide 7- amino-4-quinolone-3-carboxylique substitues de maniere heterocyclique, methode pour leur production et leur utilisation en tant que medicaments | |
EA200400882A1 (ru) | ЗАМЕЩЁННЫЕ ПРОИЗВОДНЫЕ МЕТИЛЕНАМИДА В КАЧЕСТВЕ МОДУЛЯТОРОВ ПРОТЕИНТИРОЗИНФОСФАТАЗ ( PTPs ) | |
ATE455772T1 (de) | Alkinylarylcarbonsäureamide | |
NO20074639L (no) | Krystallinsk base av trans-1-((1R,3S)-6-klor-3-fenylindan-1-yl)-3,3-dimetylpiperazin | |
TW200609228A (en) | Substituted n-acyl-2-aminothiazoles | |
TW200740786A (en) | Novel cercosporamide derivatives | |
BRPI0607558A2 (pt) | derivados do ácido aminobutanóico, inibidor da carnitina palmitoil transferase(cpt) | |
TWI256952B (en) | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders | |
NO20054148L (no) | Nytt medikament |