|
NL154600B
(nl)
|
1971-02-10 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
|
|
US3687808A
(en)
|
1969-08-14 |
1972-08-29 |
Univ Leland Stanford Junior |
Synthetic polynucleotides
|
|
US3715345A
(en)
|
1970-08-03 |
1973-02-06 |
Lilly Co Eli |
Glucagon separation process
|
|
NL154598B
(nl)
|
1970-11-10 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
|
|
NL154599B
(nl)
|
1970-12-28 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
|
|
US3901654A
(en)
|
1971-06-21 |
1975-08-26 |
Biological Developments |
Receptor assays of biologically active compounds employing biologically specific receptors
|
|
US3853987A
(en)
|
1971-09-01 |
1974-12-10 |
W Dreyer |
Immunological reagent and radioimmuno assay
|
|
US3867517A
(en)
|
1971-12-21 |
1975-02-18 |
Abbott Lab |
Direct radioimmunoassay for antigens and their antibodies
|
|
NL171930C
(nl)
|
1972-05-11 |
1983-06-01 |
Akzo Nv |
Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
|
|
US3850578A
(en)
|
1973-03-12 |
1974-11-26 |
H Mcconnell |
Process for assaying for biologically active molecules
|
|
US3876623A
(en)
|
1973-05-09 |
1975-04-08 |
Lilly Co Eli |
Process for purifying insulin
|
|
US3863008A
(en)
|
1973-06-11 |
1975-01-28 |
American Home Prod |
Somatostatin as stimulant of luteinizing hormone secretion
|
|
US3935074A
(en)
|
1973-12-17 |
1976-01-27 |
Syva Company |
Antibody steric hindrance immunoassay with two antibodies
|
|
US3996345A
(en)
|
1974-08-12 |
1976-12-07 |
Syva Company |
Fluorescence quenching with immunological pairs in immunoassays
|
|
US4034074A
(en)
|
1974-09-19 |
1977-07-05 |
The Board Of Trustees Of Leland Stanford Junior University |
Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
|
|
US3984533A
(en)
|
1975-11-13 |
1976-10-05 |
General Electric Company |
Electrophoretic method of detecting antigen-antibody reaction
|
|
US4036945A
(en)
|
1976-05-03 |
1977-07-19 |
The Massachusetts General Hospital |
Composition and method for determining the size and location of myocardial infarcts
|
|
US4098876A
(en)
|
1976-10-26 |
1978-07-04 |
Corning Glass Works |
Reverse sandwich immunoassay
|
|
US4331647A
(en)
|
1980-03-03 |
1982-05-25 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
|
|
US4879219A
(en)
|
1980-09-19 |
1989-11-07 |
General Hospital Corporation |
Immunoassay utilizing monoclonal high affinity IgM antibodies
|
|
US4469863A
(en)
|
1980-11-12 |
1984-09-04 |
Ts O Paul O P |
Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
|
|
US5023243A
(en)
|
1981-10-23 |
1991-06-11 |
Molecular Biosystems, Inc. |
Oligonucleotide therapeutic agent and method of making same
|
|
US4476301A
(en)
|
1982-04-29 |
1984-10-09 |
Centre National De La Recherche Scientifique |
Oligonucleotides, a process for preparing the same and their application as mediators of the action of interferon
|
|
US4687808A
(en)
|
1982-08-12 |
1987-08-18 |
Biospecific Technologies, Inc. |
Activation of biocompatible polymers with biologicals whose binding complements are pathological effectors
|
|
IL68218A
(en)
|
1983-03-23 |
1985-12-31 |
Univ Ramot |
Compositions for cartilage repair comprising embryonal chondrocytes
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5011771A
(en)
|
1984-04-12 |
1991-04-30 |
The General Hospital Corporation |
Multiepitopic immunometric assay
|
|
US5550111A
(en)
|
1984-07-11 |
1996-08-27 |
Temple University-Of The Commonwealth System Of Higher Education |
Dual action 2',5'-oligoadenylate antiviral derivatives and uses thereof
|
|
US4666828A
(en)
|
1984-08-15 |
1987-05-19 |
The General Hospital Corporation |
Test for Huntington's disease
|
|
US5185444A
(en)
|
1985-03-15 |
1993-02-09 |
Anti-Gene Deveopment Group |
Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
|
|
US5166315A
(en)
|
1989-12-20 |
1992-11-24 |
Anti-Gene Development Group |
Sequence-specific binding polymers for duplex nucleic acids
|
|
US5405938A
(en)
|
1989-12-20 |
1995-04-11 |
Anti-Gene Development Group |
Sequence-specific binding polymers for duplex nucleic acids
|
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
US5235033A
(en)
|
1985-03-15 |
1993-08-10 |
Anti-Gene Development Group |
Alpha-morpholino ribonucleoside derivatives and polymers thereof
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4801531A
(en)
|
1985-04-17 |
1989-01-31 |
Biotechnology Research Partners, Ltd. |
Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
|
|
US4980286A
(en)
|
1985-07-05 |
1990-12-25 |
Whitehead Institute For Biomedical Research |
In vivo introduction and expression of foreign genetic material in epithelial cells
|
|
ATE68013T1
(de)
|
1985-07-05 |
1991-10-15 |
Whitehead Biomedical Inst |
Expression von fremdem genetischem material in epithelzellen.
|
|
GB8606913D0
(en)
|
1986-03-20 |
1986-04-23 |
Hider R C |
Treatment of sickle cell disease
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
EP0260032B1
(en)
|
1986-09-08 |
1994-01-26 |
Ajinomoto Co., Inc. |
Compounds for the cleavage at a specific position of RNA, oligomers employed for the formation of said compounds, and starting materials for the synthesis of said oligomers
|
|
US5264423A
(en)
|
1987-03-25 |
1993-11-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Inhibitors for replication of retroviruses and for the expression of oncogene products
|
|
US5276019A
(en)
|
1987-03-25 |
1994-01-04 |
The United States Of America As Represented By The Department Of Health And Human Services |
Inhibitors for replication of retroviruses and for the expression of oncogene products
|
|
US5166320A
(en)
|
1987-04-22 |
1992-11-24 |
University Of Connecticut |
Carrier system and method for the introduction of genes into mammalian cells
|
|
US4806484A
(en)
|
1987-08-07 |
1989-02-21 |
Igb Products, Ltd. |
Perfusion airlift bioreactor
|
|
JP3015383B2
(ja)
|
1987-09-11 |
2000-03-06 |
ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ |
形質導入した線維芽およびそれらの使用
|
|
US4924624A
(en)
|
1987-10-22 |
1990-05-15 |
Temple University-Of The Commonwealth System Of Higher Education |
2,',5'-phosphorothioate oligoadenylates and plant antiviral uses thereof
|
|
US5188897A
(en)
|
1987-10-22 |
1993-02-23 |
Temple University Of The Commonwealth System Of Higher Education |
Encapsulated 2',5'-phosphorothioate oligoadenylates
|
|
US5403711A
(en)
|
1987-11-30 |
1995-04-04 |
University Of Iowa Research Foundation |
Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved
|
|
ATE151467T1
(de)
|
1987-11-30 |
1997-04-15 |
Univ Iowa Res Found |
Durch modifikationen an der 3'-terminalen phosphodiesterbindung stabilisierte dna moleküle, ihre verwendung als nukleinsäuresonden sowie als therapeutische mittel zur hemmung der expression spezifischer zielgene
|
|
JP2914692B2
(ja)
|
1987-12-11 |
1999-07-05 |
ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ |
内皮細胞の遺伝子修飾
|
|
JP2917998B2
(ja)
|
1988-02-05 |
1999-07-12 |
ホワイトヘッド・インスティチュート・フォー・バイオメディカル・リサーチ |
修飾された肝細胞およびその用途
|
|
JPH01222780A
(ja)
|
1988-03-02 |
1989-09-06 |
Tosoh Corp |
ウロキナーゼ前駆体様蛋白質のリフォールディング方法
|
|
WO1989009221A1
(en)
|
1988-03-25 |
1989-10-05 |
University Of Virginia Alumni Patents Foundation |
Oligonucleotide n-alkylphosphoramidates
|
|
US5081035A
(en)
|
1988-04-18 |
1992-01-14 |
The University Of Michigan |
Bioreactor system
|
|
US5278302A
(en)
|
1988-05-26 |
1994-01-11 |
University Patents, Inc. |
Polynucleotide phosphorodithioates
|
|
US5216141A
(en)
|
1988-06-06 |
1993-06-01 |
Benner Steven A |
Oligonucleotide analogs containing sulfur linkages
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5272057A
(en)
|
1988-10-14 |
1993-12-21 |
Georgetown University |
Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
|
|
US5256775A
(en)
|
1989-06-05 |
1993-10-26 |
Gilead Sciences, Inc. |
Exonuclease-resistant oligonucleotides
|
|
US5399493A
(en)
|
1989-06-15 |
1995-03-21 |
The Regents Of The University Of Michigan |
Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
|
|
US5437994A
(en)
|
1989-06-15 |
1995-08-01 |
Regents Of The University Of Michigan |
Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
|
|
US5192659A
(en)
|
1989-08-25 |
1993-03-09 |
Genetype Ag |
Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
|
|
US5399676A
(en)
|
1989-10-23 |
1995-03-21 |
Gilead Sciences |
Oligonucleotides with inverted polarity
|
|
US5264564A
(en)
|
1989-10-24 |
1993-11-23 |
Gilead Sciences |
Oligonucleotide analogs with novel linkages
|
|
US5264562A
(en)
|
1989-10-24 |
1993-11-23 |
Gilead Sciences, Inc. |
Oligonucleotide analogs with novel linkages
|
|
US5177198A
(en)
|
1989-11-30 |
1993-01-05 |
University Of N.C. At Chapel Hill |
Process for preparing oligoribonucleoside and oligodeoxyribonucleoside boranophosphates
|
|
US5587361A
(en)
|
1991-10-15 |
1996-12-24 |
Isis Pharmaceuticals, Inc. |
Oligonucleotides having phosphorothioate linkages of high chiral purity
|
|
US5623065A
(en)
|
1990-08-13 |
1997-04-22 |
Isis Pharmaceuticals, Inc. |
Gapped 2' modified oligonucleotides
|
|
US5149797A
(en)
|
1990-02-15 |
1992-09-22 |
The Worcester Foundation For Experimental Biology |
Method of site-specific alteration of rna and production of encoded polypeptides
|
|
US5220007A
(en)
|
1990-02-15 |
1993-06-15 |
The Worcester Foundation For Experimental Biology |
Method of site-specific alteration of RNA and production of encoded polypeptides
|
|
US5321131A
(en)
|
1990-03-08 |
1994-06-14 |
Hybridon, Inc. |
Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling
|
|
US5470967A
(en)
|
1990-04-10 |
1995-11-28 |
The Dupont Merck Pharmaceutical Company |
Oligonucleotide analogs with sulfamate linkages
|
|
US5612211A
(en)
|
1990-06-08 |
1997-03-18 |
New York University |
Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
|
|
US6326198B1
(en)
|
1990-06-14 |
2001-12-04 |
Regents Of The University Of Michigan |
Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
|
|
US5677437A
(en)
|
1990-07-27 |
1997-10-14 |
Isis Pharmaceuticals, Inc. |
Heteroatomic oligonucleoside linkages
|
|
US5610289A
(en)
|
1990-07-27 |
1997-03-11 |
Isis Pharmaceuticals, Inc. |
Backbone modified oligonucleotide analogues
|
|
US5541307A
(en)
|
1990-07-27 |
1996-07-30 |
Isis Pharmaceuticals, Inc. |
Backbone modified oligonucleotide analogs and solid phase synthesis thereof
|
|
US5489677A
(en)
|
1990-07-27 |
1996-02-06 |
Isis Pharmaceuticals, Inc. |
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
|
|
US5618704A
(en)
|
1990-07-27 |
1997-04-08 |
Isis Pharmacueticals, Inc. |
Backbone-modified oligonucleotide analogs and preparation thereof through radical coupling
|
|
US5608046A
(en)
|
1990-07-27 |
1997-03-04 |
Isis Pharmaceuticals, Inc. |
Conjugated 4'-desmethyl nucleoside analog compounds
|
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
|
US5623070A
(en)
|
1990-07-27 |
1997-04-22 |
Isis Pharmaceuticals, Inc. |
Heteroatomic oligonucleoside linkages
|
|
ATE131827T1
(de)
|
1990-08-03 |
1996-01-15 |
Sterling Winthrop Inc |
Verbindungen und verfahren zur unterdrückung der genexpression
|
|
US5177196A
(en)
|
1990-08-16 |
1993-01-05 |
Microprobe Corporation |
Oligo (α-arabinofuranosyl nucleotides) and α-arabinofuranosyl precursors thereof
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
CA2089661C
(en)
|
1990-08-29 |
2007-04-03 |
Nils Lonberg |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5214134A
(en)
|
1990-09-12 |
1993-05-25 |
Sterling Winthrop Inc. |
Process of linking nucleosides with a siloxane bridge
|
|
US5561225A
(en)
|
1990-09-19 |
1996-10-01 |
Southern Research Institute |
Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages
|
|
EP0549686A4
(en)
|
1990-09-20 |
1995-01-18 |
Gilead Sciences Inc |
Modified internucleoside linkages
|
|
ES2096750T3
(es)
|
1990-10-31 |
1997-03-16 |
Somatix Therapy Corp |
Vectores retroviricos utiles para la terapia genica.
|
|
US5486359A
(en)
|
1990-11-16 |
1996-01-23 |
Osiris Therapeutics, Inc. |
Human mesenchymal stem cells
|
|
US5539082A
(en)
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
|
US5714331A
(en)
|
1991-05-24 |
1998-02-03 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
|
|
US5851832A
(en)
|
1991-07-08 |
1998-12-22 |
Neurospheres, Ltd. |
In vitro growth and proliferation of multipotent neural stem cells and their progeny
|
|
US5571799A
(en)
|
1991-08-12 |
1996-11-05 |
Basco, Ltd. |
(2'-5') oligoadenylate analogues useful as inhibitors of host-v5.-graft response
|
|
CA2123094C
(en)
|
1991-11-06 |
1999-08-10 |
Paulo N. Correa |
Cell culture medium
|
|
US5700922A
(en)
|
1991-12-24 |
1997-12-23 |
Isis Pharmaceuticals, Inc. |
PNA-DNA-PNA chimeric macromolecules
|
|
AU685743B2
(en)
|
1992-03-04 |
1998-01-29 |
Regents Of The University Of Michigan, The |
Methods, compositions and devices for maintaining and growing human stem and/or hematopoietic cells
|
|
US5792751A
(en)
|
1992-04-13 |
1998-08-11 |
Baylor College Of Medicine |
Tranformation of cells associated with fluid spaces
|
|
US5633360A
(en)
|
1992-04-14 |
1997-05-27 |
Gilead Sciences, Inc. |
Oligonucleotide analogs capable of passive cell membrane permeation
|
|
US5434257A
(en)
|
1992-06-01 |
1995-07-18 |
Gilead Sciences, Inc. |
Binding compentent oligomers containing unsaturated 3',5' and 2',5' linkages
|
|
US5281521A
(en)
|
1992-07-20 |
1994-01-25 |
The Trustees Of The University Of Pennsylvania |
Modified avidin-biotin technique
|
|
US5652355A
(en)
|
1992-07-23 |
1997-07-29 |
Worcester Foundation For Experimental Biology |
Hybrid oligonucleotide phosphorothioates
|
|
US5320963A
(en)
|
1992-11-25 |
1994-06-14 |
National Research Council Of Canada |
Bioreactor for the perfusion culture of cells
|
|
US5476925A
(en)
|
1993-02-01 |
1995-12-19 |
Northwestern University |
Oligodeoxyribonucleotides including 3'-aminonucleoside-phosphoramidate linkages and terminal 3'-amino groups
|
|
WO1994018991A1
(en)
|
1993-02-19 |
1994-09-01 |
Celtrix Pharmaceuticals, Inc. |
EXPANSION OF STEM CELLS IN LONG TERM BONE MARROW CULTURES BY NEUTRALIZATION OF TGF-$g(b)
|
|
US5654186A
(en)
|
1993-02-26 |
1997-08-05 |
The Picower Institute For Medical Research |
Blood-borne mesenchymal cells
|
|
GB9304618D0
(en)
|
1993-03-06 |
1993-04-21 |
Ciba Geigy Ag |
Chemical compounds
|
|
HU9501974D0
(en)
|
1993-03-31 |
1995-09-28 |
Sterling Winthrop Inc |
Oligonucleotides with amide linkages replacing phosphodiester linkages
|
|
US5342781A
(en)
|
1993-07-15 |
1994-08-30 |
Su Wei Wen W |
External-loop perfusion air-lift bioreactor
|
|
US5378725A
(en)
|
1993-07-19 |
1995-01-03 |
The Arizona Board Of Regents |
Inhibition of phosphatidylinositol 3-kinase with wortmannin and analogs thereof
|
|
WO1995004143A1
(en)
|
1993-07-28 |
1995-02-09 |
Fred Hutchinson Cancer Research Center |
Creating novel hematopoietic cell lines by expressing altered retinoic acid receptors
|
|
US5504103A
(en)
|
1993-08-25 |
1996-04-02 |
Eli Lilly And Company |
Inhibition of phosphatidylinositol 3-kinase with 17 β-hydroxywortmannin and analogs thereof
|
|
US6015686A
(en)
|
1993-09-15 |
2000-01-18 |
Chiron Viagene, Inc. |
Eukaryotic layered vector initiation systems
|
|
US5789543A
(en)
|
1993-12-30 |
1998-08-04 |
President And Fellows Of Harvard College |
Vertebrate embryonic pattern-inducing proteins and uses related thereto
|
|
US5599705A
(en)
|
1993-11-16 |
1997-02-04 |
Cameron; Robert B. |
In vitro method for producing differentiated universally compatible mature human blood cells
|
|
EP0733059B1
(en)
|
1993-12-09 |
2000-09-13 |
Thomas Jefferson University |
Compounds and methods for site-directed mutations in eukaryotic cells
|
|
US6165747A
(en)
|
1993-12-30 |
2000-12-26 |
President & Fellows Of Harvard College |
Nucleic acids encoding hedgehog proteins
|
|
US6261786B1
(en)
|
1993-12-30 |
2001-07-17 |
Imperial Cancer Res. Technology |
Screening assays for hedgehog agonists and antagonists
|
|
US6384192B1
(en)
|
1993-12-30 |
2002-05-07 |
President & Fellows Of Harvard College |
Vertebrate embryonic pattern-inducing proteins
|
|
AU687059B2
(en)
|
1994-02-09 |
1998-02-19 |
Genespan Corporation |
High performance cell culture bioreactor and method
|
|
US5631219A
(en)
|
1994-03-08 |
1997-05-20 |
Somatogen, Inc. |
Method of stimulating hematopoiesis with hemoglobin
|
|
AU687531B2
(en)
|
1994-03-11 |
1998-02-26 |
Baxter International Inc. |
Flow-through bioreactor with grooves for cell retention
|
|
US5625050A
(en)
|
1994-03-31 |
1997-04-29 |
Amgen Inc. |
Modified oligonucleotides and intermediates useful in nucleic acid therapeutics
|
|
US5489304A
(en)
|
1994-04-19 |
1996-02-06 |
Brigham & Women's Hospital |
Method of skin regeneration using a collagen-glycosaminoglycan matrix and cultured epithelial autograft
|
|
US5480906A
(en)
|
1994-07-01 |
1996-01-02 |
Eli Lilly And Company |
Stereochemical Wortmannin derivatives
|
|
US5807718A
(en)
|
1994-12-02 |
1998-09-15 |
The Scripps Research Institute |
Enzymatic DNA molecules
|
|
US5770378A
(en)
|
1994-12-30 |
1998-06-23 |
Ligand Pharmaceuticals, Inc. |
Tricyclic retinoids, methods for their production and use
|
|
US5736396A
(en)
|
1995-01-24 |
1998-04-07 |
Case Western Reserve University |
Lineage-directed induction of human mesenchymal stem cell differentiation
|
|
US6077947A
(en)
|
1995-02-02 |
2000-06-20 |
Cell Genesys, Inc. |
DNA encoding an intracellular chimeric receptor comprising Janus kinase
|
|
US5716616A
(en)
|
1995-03-28 |
1998-02-10 |
Thomas Jefferson University |
Isolated stromal cells for treating diseases, disorders or conditions characterized by bone defects
|
|
US5733541A
(en)
|
1995-04-21 |
1998-03-31 |
The Regent Of The University Of Michigan |
Hematopoietic cells: compositions and methods
|
|
US5925567A
(en)
|
1995-05-19 |
1999-07-20 |
T. Breeders, Inc. |
Selective expansion of target cell populations
|
|
US5674750A
(en)
|
1995-05-19 |
1997-10-07 |
T. Breeders |
Continuous selective clonogenic expansion of relatively undifferentiated cells
|
|
US5712154A
(en)
|
1995-06-07 |
1998-01-27 |
W.R. Grace & Co.-Conn. |
Dual fiber bioreactor
|
|
US5728581A
(en)
|
1995-06-07 |
1998-03-17 |
Systemix, Inc. |
Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
|
|
US6680166B1
(en)
|
1995-06-07 |
2004-01-20 |
Claudy Jean Paul Mullon |
Dual fiber bioreactor
|
|
US6306575B1
(en)
|
1995-06-16 |
2001-10-23 |
Stemcell Technologies, Inc. |
Methods for preparing enriched human hematopoietic cell preparations
|
|
WO1997004707A1
(en)
|
1995-07-28 |
1997-02-13 |
Apls Co., Ltd. |
Assembly for adjusting piercing depth of lancet
|
|
US5652356A
(en)
|
1995-08-17 |
1997-07-29 |
Hybridon, Inc. |
Inverted chimeric and hybrid oligonucleotides
|
|
US6117850A
(en)
|
1995-08-28 |
2000-09-12 |
The Collaborative Group, Ltd. |
Mobilization of peripheral blood precursor cells by β(1,3)-glucan
|
|
US5952345A
(en)
|
1995-09-01 |
1999-09-14 |
Allergan Sales, Inc. |
Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
|
|
US5776699A
(en)
|
1995-09-01 |
1998-07-07 |
Allergan, Inc. |
Method of identifying negative hormone and/or antagonist activities
|
|
US6218128B1
(en)
|
1997-09-12 |
2001-04-17 |
Allergan Sales, Inc. |
Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities
|
|
US6008204A
(en)
|
1995-09-01 |
1999-12-28 |
Allergan Sales, Inc. |
Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
|
|
US5958954A
(en)
|
1995-09-01 |
1999-09-28 |
Allergan Sales, Inc. |
Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
|
|
US6329169B1
(en)
|
1995-09-29 |
2001-12-11 |
Human Genome Sciences, Inc. |
Nucleic acid molecules encoding cytostatin II
|
|
FR2739777B1
(fr)
|
1995-10-11 |
1997-11-14 |
Cird Galderma |
Ligand antagoniste rar-gamma ou agoniste rar-alpha en tant qu'inhibiteur d'apoptose
|
|
CA2247926A1
(en)
|
1996-03-01 |
1997-09-04 |
Imclone Systems Incorporated |
Use of delta-like protein to inhibit the differentiation of stem cells
|
|
US5877207A
(en)
|
1996-03-11 |
1999-03-02 |
Allergan Sales, Inc. |
Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
|
|
EP0891419A4
(en)
|
1996-03-12 |
2000-03-01 |
Life Technologies Inc |
NUTRIENT ADDITIVE FOR HEMATOPOETIC CELL CULTURES
|
|
US6043092A
(en)
|
1996-03-18 |
2000-03-28 |
University Of Pittsburgh |
Cell culture media for mammalian cells
|
|
US5945309A
(en)
|
1996-03-19 |
1999-08-31 |
Human Genome Sciences, Inc. |
Cytostatin III nucleic acids encoding
|
|
TW442459B
(en)
|
1996-04-15 |
2001-06-23 |
Hoffmann La Roche |
Retinoid compounds, pharmaceutical composition comprising same and process for the preparation thereof
|
|
US6455678B1
(en)
|
1996-04-26 |
2002-09-24 |
Amcell Corporation |
Human hematopoietic stem and progenitor cell antigen
|
|
CN1217746A
(zh)
|
1996-04-29 |
1999-05-26 |
勒芬研究与发展公司 |
多能性兔胚胎干(es)细胞系及其在嵌合兔的产生中的应用
|
|
US5851984A
(en)
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
|
ATE236654T1
(de)
|
1996-08-28 |
2003-04-15 |
Inst Nat Sante Rech Med |
Therapeutische kombinationen von rar-antagonisten und rxr-agonisten
|
|
US5945337A
(en)
|
1996-10-18 |
1999-08-31 |
Quality Biological, Inc. |
Method for culturing CD34+ cells in a serum-free medium
|
|
AU731937B2
(en)
|
1996-12-10 |
2001-04-05 |
Hadasit Medical Research Services & Development Company Ltd |
Serum-derived factor inducing cell differentiation and medical uses thereof
|
|
US6335195B1
(en)
|
1997-01-28 |
2002-01-01 |
Maret Corporation |
Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
|
|
CA2196496A1
(en)
|
1997-01-31 |
1998-07-31 |
Stephen William Watson Michnick |
Protein fragment complementation assay for the detection of protein-protein interactions
|
|
US6294330B1
(en)
|
1997-01-31 |
2001-09-25 |
Odyssey Pharmaceuticals Inc. |
Protein fragment complementation assays for the detection of biological or drug interactions
|
|
US20030215445A1
(en)
|
1997-05-23 |
2003-11-20 |
Ginette Serrero |
Methods and compositions for inhibiting the growth of hematopoietic malignant cells
|
|
US6372473B1
(en)
|
1997-05-28 |
2002-04-16 |
Human Genome Sciences, Inc. |
Tissue plasminogen activator-like protease
|
|
JP2002513295A
(ja)
|
1997-07-08 |
2002-05-08 |
ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド |
１２３種類のヒト分泌タンパク質
|
|
IT1293827B1
(it)
|
1997-08-07 |
1999-03-10 |
Dompe Spa |
Metodo per l'espansione ex vivo di cellule staminali emopoietiche
|
|
US6440734B1
(en)
|
1998-09-25 |
2002-08-27 |
Cytomatrix, Llc |
Methods and devices for the long-term culture of hematopoietic progenitor cells
|
|
FR2769491B1
(fr)
|
1997-10-15 |
2000-01-07 |
Patrick Sangouard |
Sphincter artificiel reglable a commande magnetique
|
|
JP3704471B2
(ja)
|
1997-11-12 |
2005-10-12 |
エフ．ホフマン−ラ ロシュ アーゲー |
レチノイド拮抗薬を用いるヘルパーｔ細胞媒介性免疫疾患の処置
|
|
US6248587B1
(en)
|
1997-11-26 |
2001-06-19 |
University Of Southern Cailfornia |
Method for promoting mesenchymal stem and lineage-specific cell proliferation
|
|
EP1332673B1
(en)
|
1998-02-17 |
2012-05-30 |
Gamida Cell Ltd. |
Method of controlling proliferation and differentiation of stem and progenitor cells
|
|
US6962698B1
(en)
|
1998-02-17 |
2005-11-08 |
Gamida Cell Ltd. |
Methods of controlling proliferation and differentiation of stem and progenitor cells
|
|
US6886568B2
(en)
|
1998-04-08 |
2005-05-03 |
The Johns Hopkins University |
Method for fabricating cell-containing implants
|
|
US6413773B1
(en)
|
1998-06-01 |
2002-07-02 |
The Regents Of The University Of California |
Phosphatidylinositol 3-kinase inhibitors as stimulators of endocrine differentiation
|
|
JP4526186B2
(ja)
|
1998-06-08 |
2010-08-18 |
オシリス セラピューティクス，インコーポレイテッド |
造血幹細胞を試験管内で維持する方法と組成物
|
|
DK1084230T3
(da)
|
1998-06-08 |
2008-03-03 |
Osiris Therapeutics Inc |
Regulering af hæmatopoietisk stamcelledifferentiering ved anvendelse af humane mesenkymstamceller
|
|
US6284540B1
(en)
|
1998-09-29 |
2001-09-04 |
Washington University |
Artemin, a novel neurotrophic factor
|
|
IL142094A0
(en)
|
1998-09-29 |
2002-03-10 |
Gamida Cell Ltd |
Methods of controlling proliferation and differentiation of stem and progenitor cells
|
|
US6667176B1
(en)
|
2000-01-11 |
2003-12-23 |
Geron Corporation |
cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
|
|
CA2254429A1
(en)
|
1998-11-19 |
2000-05-19 |
Tully Michael Underhill |
Compositions for promoting chondrogenesis
|
|
EP2314700A1
(en)
|
1999-01-28 |
2011-04-27 |
Medical College of Georgia Research Institute, Inc |
Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA
|
|
EP1147176B1
(en)
|
1999-02-04 |
2009-12-16 |
Pluristem Ltd. |
Method and apparatus for maintenance and expansion of hemopoietic stem cells and/or progenitor cells
|
|
US6887468B1
(en)
|
1999-04-28 |
2005-05-03 |
Board Of Regents, The University Of Texas System |
Antibody kits for selectively inhibiting VEGF
|
|
DE19919242A1
(de)
|
1999-04-28 |
2000-11-02 |
Creavis Tech & Innovation Gmbh |
Modulare Zellträgersysteme für dreidimensionales Zellwachstum
|
|
AU4860900A
(en)
|
1999-06-02 |
2000-12-18 |
Lifebank Services, L.L.C. |
Methods of isolation, cryopreservation, and therapeutic use of human amniotic epithelial cells
|
|
US6652872B2
(en)
|
1999-07-06 |
2003-11-25 |
Ramat At Tel Aviv University Ltd. |
Scaffold formed of tissue treated to eliminate cellular and cytosolic elements
|
|
US20020159984A1
(en)
|
1999-11-12 |
2002-10-31 |
Quality Biological, Inc. |
Cultivation of cells for long term engraftment
|
|
US6541249B2
(en)
|
1999-12-22 |
2003-04-01 |
Human Genome Sciences, Inc. |
Immortalized human stromal cell lines
|
|
US6303374B1
(en)
|
2000-01-18 |
2001-10-16 |
Isis Pharmaceuticals Inc. |
Antisense modulation of caspase 3 expression
|
|
CA2411849A1
(en)
|
2000-06-05 |
2001-12-13 |
The Burnham Institute |
Methods of differentiating and protecting cells by modulating the p38/mef2 pathway
|
|
US7045353B2
(en)
|
2000-08-01 |
2006-05-16 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Directed differentiation of human embryonic cells
|
|
US7198940B2
(en)
|
2000-10-25 |
2007-04-03 |
Shot Hardware Optimization Technology, Inc. |
Bioreactor apparatus and cell culturing system
|
|
ES2171131B1
(es)
|
2000-11-10 |
2003-12-16 |
Idebio S L |
Plaguicida biologico a base de quitosano
|
|
US6642019B1
(en)
|
2000-11-22 |
2003-11-04 |
Synthecan, Inc. |
Vessel, preferably spherical or oblate spherical for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same
|
|
EP2316919B1
(en)
|
2001-02-14 |
2015-10-07 |
Anthrogenesis Corporation |
Post-partum mammalian placenta, its use and placental stem cells therefrom
|
|
EP1385935A4
(en)
|
2001-03-29 |
2004-09-15 |
Ixion Biotechnology Inc |
METHOD FOR TRANSDIFFERENTIATION OF NON-PANCREATIC STEM CELLS IN THE PANCREAS DIFFERENTIATION PATHWAY
|
|
CA2446806A1
(en)
|
2001-05-11 |
2002-11-21 |
Board Of Regents, The University Of Texas System |
Anti-cd26 monoclonal antibodies as therapy for diseases associated with cells expressing cd26
|
|
US20030017134A1
(en)
|
2001-06-19 |
2003-01-23 |
Technion Research And Development Foundation Ltd. |
Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer
|
|
DE10131388B4
(de)
|
2001-06-28 |
2004-07-08 |
Infineon Technologies Ag |
Integrierter dynamischer Speicher und Verfahren zum Betrieb desselben
|
|
CA2351156A1
(en)
|
2001-07-04 |
2003-01-04 |
Peter W. Zandstra |
A bioprocess for the generation of pluripotent cell derived cells and tissues
|
|
WO2003014336A1
(fr)
|
2001-08-07 |
2003-02-20 |
Kirin Beer Kabushiki Kaisha |
Procede de preparation de cellules souches hematopoietiques multipotentes
|
|
US6908932B2
(en)
|
2001-10-24 |
2005-06-21 |
Iconix Pharmaceuticals, Inc. |
Modulators of phosphoinositide 3-kinase
|
|
US6887401B2
(en)
|
2001-11-05 |
2005-05-03 |
Essilor International Compagnie General D'optique |
Method for making transparent polythiourethane substrates in particular optical substrates
|
|
AUPR892501A0
(en)
|
2001-11-16 |
2001-12-13 |
Peter Maccallum Cancer Institute, The |
Method of enhancing self renewal of stem cells and uses thereof
|
|
US20050095228A1
(en)
|
2001-12-07 |
2005-05-05 |
Fraser John K. |
Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
|
|
US7514075B2
(en)
|
2001-12-07 |
2009-04-07 |
Cytori Therapeutics, Inc. |
Systems and methods for separating and concentrating adipose derived stem cells from tissue
|
|
DE10162814B4
(de)
|
2001-12-19 |
2005-06-23 |
Henkel Kgaa |
Rekonstruiertes Haarfollikelmodell
|
|
IL152904A0
(en)
|
2002-01-24 |
2003-06-24 |
Gamida Cell Ltd |
Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
|
|
EP1465982A4
(en)
|
2002-01-25 |
2006-06-07 |
Gamida Cell Ltd |
PROCESS FOR EXPANSION OF STEM AND PRESERVATIVE CELLS AND EXPANDED CELL POPULATIONS THEREWITH OBTAINED
|
|
MY156407A
(en)
|
2002-02-28 |
2016-02-26 |
Novartis Ag |
5-phenylthiazole derivatives and use as p13 kinase inhibitors
|
|
AU2003214614B2
(en)
|
2002-03-18 |
2008-11-20 |
Gamida-Cell Ltd. |
Methods of inducing differentiation in ex vivo expanded stem cells
|
|
US7498171B2
(en)
|
2002-04-12 |
2009-03-03 |
Anthrogenesis Corporation |
Modulation of stem and progenitor cell differentiation, assays, and uses thereof
|
|
US7247477B2
(en)
|
2002-04-16 |
2007-07-24 |
Technion Research & Development Foundation Ltd. |
Methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells
|
|
EP1534820A4
(en)
|
2002-08-19 |
2006-04-26 |
Gamida Cell Ltd |
EX-VIVO EXPANSION OF HUMATOPOETIC STEM CELL POPULATIONS IN MONONUCLEOUS CELL CULTURES
|
|
US20050054097A1
(en)
|
2002-11-17 |
2005-03-10 |
Tony Peled |
EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures
|
|
US7470538B2
(en)
|
2002-12-05 |
2008-12-30 |
Case Western Reserve University |
Cell-based therapies for ischemia
|
|
EP1601759A4
(en)
|
2003-03-07 |
2007-02-14 |
Gamida Cell Ltd |
EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING PI-3 KINASE MODULATORS
|
|
US20040247574A1
(en)
|
2003-05-27 |
2004-12-09 |
Christopherson Kent W. |
Methods for enhancing stem cell engraftment during transplantation
|
|
IL161903A0
(en)
|
2003-07-17 |
2005-11-20 |
Gamida Cell Ltd |
Ex vivo progenitor and stem cell expansion for usein the treatment of disease of endodermally- deri ved organs
|
|
EP1649007A4
(en)
|
2003-07-17 |
2008-05-14 |
Gamida Cell Ltd |
PROCESS FOR THE EX-VIVO EXPANSION OF STEM / PROVIDER CELLS
|
|
US7435596B2
(en)
|
2004-11-04 |
2008-10-14 |
St. Jude Children's Research Hospital, Inc. |
Modified cell line and method for expansion of NK cell
|
|
US20050260748A1
(en)
|
2004-02-27 |
2005-11-24 |
Michigan State University |
Adult stem cells and uses thereof
|
|
WO2005086845A2
(en)
|
2004-03-10 |
2005-09-22 |
Regents Of The University Of California |
Compositions and methods for growth of embryonic stem cells
|
|
WO2006030442A2
(en)
|
2004-09-16 |
2006-03-23 |
Gamida-Cell Ltd. |
Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells
|
|
CA2589034C
(en)
|
2004-11-02 |
2016-05-31 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Compositions and methods for treating hyperproliferative disorders
|
|
MX2007009173A
(es)
|
2005-01-31 |
2008-03-10 |
Cognate Therapeutics Inc |
Celulas estromaticas de adulto derivadas de adiposo que exhiben caracteristicas de celulas endoteliales.
|
|
WO2007063545A2
(en)
|
2005-11-29 |
2007-06-07 |
Gamida-Cell Ltd. |
Methods of improving stem cell homing and engraftment
|
|
US8846393B2
(en)
|
2005-11-29 |
2014-09-30 |
Gamida-Cell Ltd. |
Methods of improving stem cell homing and engraftment
|
|
US20100021434A1
(en)
|
2005-12-08 |
2010-01-28 |
Ramot At Tel Aviv University Ltd. |
Isolated Oligodendrocyte-Like Cells and Populations Comprising Same for the Treatment of CNS Diseases
|
|
AU2007285057B2
(en)
*
|
2006-08-15 |
2013-08-01 |
Agency For Science, Technology And Research |
Mesenchymal stem cell conditioned medium
|
|
JP2010509316A
(ja)
|
2006-11-09 |
2010-03-25 |
ガミダ セル リミテッド |
末梢血管疾患を治療するためのエクスビボ培養された造血細胞の使用
|
|
KR100995835B1
(ko)
*
|
2007-12-18 |
2010-11-23 |
동국대학교 산학협력단 |
탯줄 유래의 중간엽 줄기세포를 이용한 간-특이기능이 있는간세포의 제조방법 및 이로부터 제조된 탯줄 유래 간세포
|
|
US20090257987A1
(en)
|
2008-04-10 |
2009-10-15 |
Ramot At Tel Aviv University Ltd. |
Method of generating dopamine-secreting cells
|
|
US8062632B2
(en)
|
2008-06-23 |
2011-11-22 |
National Yang-Ming University |
Systems and methods for making hepatocytes from extrahepatic somatic stem cells and use thereof
|
|
TWI397585B
(zh)
|
2008-07-16 |
2013-06-01 |
Univ Nat Taiwan |
細胞培養方法及其應用
|
|
GB0818725D0
(en)
|
2008-10-13 |
2008-11-19 |
Habib Nagy A |
Pharmaceutical composition
|
|
PE20100362A1
(es)
|
2008-10-30 |
2010-05-27 |
Irm Llc |
Derivados de purina que expanden las celulas madre hematopoyeticas
|
|
JP5606008B2
(ja)
|
2009-04-13 |
2014-10-15 |
三菱重工業株式会社 |
骨髄間質細胞及び間葉系幹細胞の培養方法、中枢神経系疾患治療用の移植細胞の製造方法
|
|
EP2333047A1
(en)
|
2009-12-09 |
2011-06-15 |
Fresenius Medical Care Deutschland GmbH |
Adult stem cell derived conditioned medium and/or adult stem cells for use in the therapeutic treatment of a tumor disease
|
|
WO2011080740A1
(en)
|
2009-12-29 |
2011-07-07 |
Gamida-Cell Ltd. |
Methods for enhancing natural killer cell proliferation and activity
|
|
KR101869077B1
(ko)
*
|
2010-05-03 |
2018-06-22 |
더 텍사스 에이 & 엠 유니버시티 시스템 |
눈 손상 및 질환 치료용 성체 줄기 세포／전구 세포 및 줄기 세포 단백질
|
|
IN2014MN01680A
(US20090226406A1-20090910-C00003.png)
|
2012-02-13 |
2015-07-03 |
Gamida Cell Ltd |
|
|
US9175266B2
(en)
|
2012-07-23 |
2015-11-03 |
Gamida Cell Ltd. |
Enhancement of natural killer (NK) cell proliferation and activity
|
|
US9567569B2
(en)
|
2012-07-23 |
2017-02-14 |
Gamida Cell Ltd. |
Methods of culturing and expanding mesenchymal stem cells
|
