IN2014DN10551A - - Google Patents

Info

Publication number
IN2014DN10551A
IN2014DN10551A IN10551DEN2014A IN2014DN10551A IN 2014DN10551 A IN2014DN10551 A IN 2014DN10551A IN 10551DEN2014 A IN10551DEN2014 A IN 10551DEN2014A IN 2014DN10551 A IN2014DN10551 A IN 2014DN10551A
Authority
IN
India
Prior art keywords
derivatives
antifungal
semisynthetic
complexes
plant
Prior art date
Application number
Other languages
English (en)
Inventor
Edward Borowski
Natalia Salewska
Majewska Joanna Boros
Maria Milewska
Malgorzata Wysocka
Slawomir Milewski
Izabela Lacka
Michal Sabisz
Original Assignee
Blirt S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blirt S A filed Critical Blirt S A
Publication of IN2014DN10551A publication Critical patent/IN2014DN10551A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IN10551DEN2014 2012-06-15 2013-06-14 IN2014DN10551A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL39954512 2012-06-15
PCT/EP2013/062436 WO2013186384A1 (en) 2012-06-15 2013-06-14 N-substituted second generation derivatives of antifungal antibiotic amphotericin b and methods of their preparation and application

Publications (1)

Publication Number Publication Date
IN2014DN10551A true IN2014DN10551A (de) 2015-08-21

Family

ID=48626066

Family Applications (1)

Application Number Title Priority Date Filing Date
IN10551DEN2014 IN2014DN10551A (de) 2012-06-15 2013-06-14

Country Status (12)

Country Link
US (1) US9745335B2 (de)
EP (1) EP2861610A1 (de)
JP (1) JP2015519389A (de)
KR (1) KR20150027217A (de)
CN (1) CN104520309B (de)
AU (1) AU2013276480B2 (de)
BR (1) BR112014031060A2 (de)
CA (1) CA2876074A1 (de)
IN (1) IN2014DN10551A (de)
MX (1) MX2014015249A (de)
RU (1) RU2014152459A (de)
WO (1) WO2013186384A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10246478B2 (en) * 2014-06-12 2019-04-02 Shionogi & Co., Ltd. Polyene macrolide derivative
EP3283171B1 (de) * 2015-04-15 2021-05-26 Sfunga Therapeutics, Inc. Derivate von amphotericin b
EP3684373A4 (de) * 2017-09-20 2021-06-23 Atopic Medical, Inc. Zusammensetzungen und verfahren zur behandlung und linderung von atemwegserkrankungen und schleimhautentzündungen
RU2688658C1 (ru) * 2018-04-10 2019-05-22 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Противогрибковый полусинтетический полиеновый антибиотик, его водорастворимые соли и фармацевтические композиции на их основе
CN110669087B (zh) * 2018-07-02 2023-03-31 上海医药工业研究院 两性霉素b肽衍生物及其制备方法
CN113166188B (zh) * 2018-12-13 2023-06-20 正大天晴药业集团股份有限公司 两性霉素b肽衍生物
KR20220071185A (ko) * 2019-08-08 2022-05-31 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 암포테리신 b의 하이브리드 아미드 유도체
WO2022003181A1 (fr) * 2020-07-03 2022-01-06 Nanotracks Diagnostics Derivés urée de l'amphotéricine amb, compositions les contenant et leurs utilisations, dérivés isocyanate d'alkyle omega-aminés et leur utilisation pour obtenir lesdits dérivés urée
FR3112145A1 (fr) * 2020-07-03 2022-01-07 Nanotracks Diagnostics Derives uree de macrolides polyeniques, composes chimiques particuliers susceptibles d’etre utilises pour obtenir ces derives uree, compositions les contenant et utilisations
CN111875653A (zh) * 2020-08-11 2020-11-03 深圳市儿童医院 一种含二硫键的两性霉素b衍生物及其用途
RU2751333C1 (ru) * 2020-12-16 2021-07-13 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Способ получения противогрибкового полусинтетического полиенового антибиотика
CN115536716A (zh) * 2021-06-29 2022-12-30 中国科学院上海药物研究所 两性霉素b半合成衍生物及其制备方法和用途
CN113603738B (zh) * 2021-07-23 2023-05-23 西南大学 一种pH响应性两性霉素B衍生物及其制备方法和应用
CN114133428B (zh) * 2021-12-09 2023-10-27 华东理工大学 两性霉素b亲水性多肽衍生物及其应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244590A (en) * 1960-12-23 1966-04-05 Rutgers Res And Educational Fo Polyenic compounds and procedures related thereto
GB1359473A (en) 1970-11-03 1974-07-10 Prodotti Antibiotici Spa Polyenic antibiotic
PL82224B1 (de) 1971-08-13 1975-10-31
FI60877C (fi) 1971-08-13 1982-04-13 Politechnika Gdanska Foerfarande foer framstaellning av terapeutiskt aktiva i vatten laett dispergerbara polyenmakrolidantibiot-n-glykosylderivat
US4195172A (en) * 1976-04-22 1980-03-25 Politechnika Gdanska Salts of N-glycosyl derivatives of polyene macrolides, especially N-methylglucamine salts as well as the method of their preparation
PL100966B1 (pl) * 1976-04-22 1978-11-30 Sposob otrzymywania n-glikozylowych pochodnych makrolidow polienowych oraz ich soli,zwlaszcza soli n-metyloglukaminowej
DE2706156C3 (de) 1977-02-14 1981-08-20 Vsesojuznyj naučno-issledovatel'skij technologičeskij institut antibiotikov i fermentov medicinskogo naznačenija, Leningrad N,N,N-Trimethylderivate amphoterer, antimykotischer Polyenantibiotika und Verfahren zu deren Herstellung
US4144328A (en) 1977-02-28 1979-03-13 Vainshtein Viktor A N,N,N-Trimethyl derivatives of polyene amphoteric antibiotics, process of producing same and pharmaceutical composition
PL122884B1 (en) 1978-07-19 1982-08-31 Politechnika Gdanska Method of manufacture of quaternary trimethylammonium salts of inorganic derivatives of polyene macrolides
US4272525A (en) * 1978-10-23 1981-06-09 Schering Corporation Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them
PL120111B1 (en) 1978-11-10 1982-02-27 Politechnika Gdanska Process for preparing novel n-substituted derivatives of antibiotics from the group of polyenic macrolydestibiotikov iz gruppy polienovykh makrolidov
PL120035B1 (en) 1978-12-20 1982-02-27 Politechnika Gdanska Process for preparing novel methyl esters of n-substituted derivatives of antibiotics from the group of polyenic macrolydesykh proizvodnykh antibiotikov iz gruppy polienovykh makrolidov
ZA807892B (en) 1979-12-24 1981-12-30 Dumex Ltd As Water soluble guanidine derivatives of polyene marcrolides and the esters thereof
PL138831B1 (en) 1983-11-16 1986-11-29 Politechnika Gdanska Process for preparing l-aspartates of 3-/n,n-dimethylamino/-propylamides of antibiotics from polyene macrolids group
PL142848B1 (en) * 1984-10-29 1987-12-31 Politechnika Gdanska Method of obtaining derivatives of n-/n,n-dimethylaminoacyl methyl esters and 3-/n,n-dimethylamino/-propylamides of polyenic acrolydes
GB8829592D0 (en) 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds
GB8829593D0 (en) 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds
FR2654339B1 (fr) * 1989-11-14 1994-10-28 Mayoly Spindler Laboratoires Nouveaux derives solubles et non toxiques des macrolides polyeniques basiques, leur preparation et leurs applications.
GB9203476D0 (en) 1992-02-19 1992-04-08 Smithkline Beecham Plc Novel compounds
PL180253B1 (pl) * 1995-05-13 2001-01-31 Politechnika Gdanska Pochodne N-metylo-N-glikozylowe estrów metylowych antybiotyków z grupy makrolidów polienowych i ich sole oraz sposób ich otrzymywania PL PL PL PL PL PL
US5942495A (en) * 1996-05-10 1999-08-24 Btg International Limited Antibiotics
US5981721A (en) 1997-10-23 1999-11-09 Karykion Corporation Polyene macrolide schiff bases, their alkyl esters and processes for preparing polyene macrolide alkyl ester salts thereof
FR2776927B1 (fr) 1998-04-07 2002-07-05 Univ Paris Curie Compositions pour la vectorisation de molecules
JP2003519662A (ja) * 2000-01-14 2003-06-24 イントラバイオティクス ファーマシューティカルズ，インコーポレイテッド ポリエン・マクロライド誘導体並びにその製法及び使用
US6413537B1 (en) 2000-03-10 2002-07-02 Wisconsin Alumni Research Foundation Nystatin formulation having reduced toxicity
US6664241B2 (en) * 2000-05-31 2003-12-16 Micrologix Biotech Inc. Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof
JP2002096091A (ja) * 2000-09-21 2002-04-02 Hitachi Ltd 油脂分解組成物及び油脂分解方法
EP1987049A1 (de) * 2006-02-23 2008-11-05 ETH Zürich Amphotericinderivative
PL210774B1 (pl) * 2006-06-19 2012-02-29 Politechnika Gdanska Zawadzone przestrzennie amfoteryczne N-aminoacylowe pochodne amfoterycyny B, (54) sposób ich otrzymywania i zastosowanie do wytwarzania leku do zwalczania drobnoustrojów grzybowych
EP2174944A4 (de) 2007-07-30 2010-09-22 Shanghai Inst Pharm Industry Polyendiesterantibiotika

Also Published As

Publication number Publication date
CA2876074A1 (en) 2013-12-19
AU2013276480B2 (en) 2018-01-04
US20150291648A1 (en) 2015-10-15
AU2013276480A1 (en) 2015-01-15
KR20150027217A (ko) 2015-03-11
MX2014015249A (es) 2015-08-20
CN104520309A (zh) 2015-04-15
CN104520309B (zh) 2018-05-04
US9745335B2 (en) 2017-08-29
RU2014152459A (ru) 2016-08-10
WO2013186384A1 (en) 2013-12-19
BR112014031060A2 (pt) 2017-06-27
JP2015519389A (ja) 2015-07-09
EP2861610A1 (de) 2015-04-22

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