IN2012DN00338A - - Google Patents
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- Publication number
- IN2012DN00338A IN2012DN00338A IN338DEN2012A IN2012DN00338A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A IN 338DEN2012 A IN338DEN2012 A IN 338DEN2012A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A
- Authority
- IN
- India
- Prior art keywords
- methods
- relates
- present
- region containing
- containing protein
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000012535 impurity Substances 0.000 abstract 1
- 238000001742 protein purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27370909P | 2009-08-07 | 2009-08-07 | |
PCT/US2010/044539 WO2011017514A1 (en) | 2009-08-07 | 2010-08-05 | Methods for purifying a target protein from one or more impurities in a sample |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN00338A true IN2012DN00338A (enrdf_load_stackoverflow) | 2015-05-22 |
Family
ID=43544660
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN338DEN2012 IN2012DN00338A (enrdf_load_stackoverflow) | 2009-08-07 | 2010-08-05 |
Country Status (9)
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3237179B2 (ja) | 1992-03-18 | 2001-12-10 | 栗田工業株式会社 | 排超純水中の過酸化水素の除去方法 |
EP2519536A4 (en) * | 2009-12-29 | 2013-06-05 | Reddys Lab Ltd Dr | PROTEIN PURIFICATION BY ION EXCHANGE |
MX344248B (es) | 2010-05-25 | 2016-12-09 | Genentech Inc * | Metodos de purificacion de polipeptidos. |
EP2598223B1 (en) | 2010-07-30 | 2022-04-06 | EMD Millipore Corporation | Chromatography media and method |
SG185920A1 (en) | 2011-05-27 | 2012-12-28 | Abbott Biotherapeutics Corp | Dac hyp compositions and methods |
EP2721052A1 (en) * | 2011-06-16 | 2014-04-23 | DSM IP Assets B.V. | Single unit chromatography antibody purification |
DK2729482T3 (en) * | 2011-07-08 | 2018-05-07 | Merck Sharp & Dohme | PROCEDURE FOR CLEANING FC-FUSION PROTEIN |
BR112014001120A2 (pt) | 2011-07-20 | 2017-02-21 | Zepteon Incorporated | métodos de separação de polipeptídeos |
BR112014002133A2 (pt) * | 2011-08-01 | 2017-02-21 | Avaxia Biologics Inc | anticorpo policlonal bovino específico para tnf humano |
US9096648B2 (en) * | 2011-08-19 | 2015-08-04 | Emd Millipore Corporation | Methods of reducing level of one or more impurities in a sample during protein purification |
CA2847173A1 (en) * | 2011-09-01 | 2013-03-07 | Human Genome Sciences, Inc. | Viral clearance methods |
EP2578286A1 (en) * | 2011-10-04 | 2013-04-10 | Merck Patent GmbH | Method and apparatus for chromatographic purification |
MX2014005330A (es) | 2011-11-02 | 2014-09-08 | Genentech Inc | Cromatografia de sobrecarga y elucion. |
WO2013075740A1 (en) | 2011-11-23 | 2013-05-30 | Sanofi | Antibody purification method |
CN102492040B (zh) * | 2011-12-29 | 2014-06-25 | 嘉和生物药业有限公司 | 一种抗her2或/和抗her3抗体蛋白的纯化方法 |
SG10201701224UA (en) * | 2012-03-12 | 2017-04-27 | Merck Patent Gmbh | Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode |
EP2682168A1 (en) * | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
EP2889617B1 (en) | 2012-08-27 | 2017-10-11 | Asahi Kasei Medical Co., Ltd. | Antibody purification method by means of temperature-responsive chromatography |
ES2657377T3 (es) | 2012-09-11 | 2018-03-05 | Coherus Biosciences, Inc. | Etanercept plegado correctamente con alta pureza y excelente rendimiento |
ES2868093T3 (es) | 2012-09-17 | 2021-10-21 | Grace W R & Co | Medio y dispositivos de cromatografía |
US10421795B2 (en) | 2012-12-17 | 2019-09-24 | Merck Sharp & Dohme Corp. | Process for purifying insulin and analogues thereof |
PL2959509T3 (pl) | 2013-02-14 | 2018-11-30 | Hao Fong | Hybrydowy filc z nanowłókien elektroprzędziony, sposób jego wytwarzania i sposób oczyszczania biocząsteczek |
DK3301115T3 (da) * | 2013-05-06 | 2022-01-31 | Sanofi Sa | Kontinuerlig flertrinsfremgangsmåde til oprensning af antistoffer |
RU2016112549A (ru) * | 2013-09-05 | 2017-10-10 | Дженентек, Инк. | Способ для повторного использования хроматографии |
SG11201602061YA (en) * | 2013-09-17 | 2016-04-28 | Kaneka Corp | Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom |
SG10201804200WA (en) | 2013-12-12 | 2018-07-30 | Emd Millipore Corp | Protein separations using an acrylamide containing filter |
JP6612242B2 (ja) * | 2014-02-14 | 2019-11-27 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 自動化された多段階精製システム及び多段階クロマトグラフィー精製方法 |
EP3116891B1 (en) | 2014-03-10 | 2020-02-12 | Richter Gedeon Nyrt. | Immunoglobulin purification using pre-cleaning steps |
CN104826617B (zh) * | 2014-03-25 | 2017-06-13 | 西北大学 | 一种用于蛋白质分离的wax/hic双功能混合模式色谱固定相及其制备方法 |
WO2015168383A1 (en) | 2014-05-02 | 2015-11-05 | W. R. Grace & Co.-Conn. | Functionalized support material and methods of making and using functionalized support material |
US20170183376A1 (en) * | 2014-06-24 | 2017-06-29 | Insight Biopharmaceuticals Ltd. | Methods of purifying antibodies |
DE102014010353B4 (de) | 2014-07-10 | 2024-09-12 | Sartorius Stedim Biotech Gmbh | Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien |
US20170298091A1 (en) * | 2014-12-08 | 2017-10-19 | Emd Millipore Corporation | Mixed Bed Ion Exchange Adsorber |
WO2016196906A1 (en) | 2015-06-05 | 2016-12-08 | W. R. Grace & Co.-Conn. | Adsorbent bioprocessing clarification agents and methods of making and using the same |
CN109071598A (zh) * | 2016-04-05 | 2018-12-21 | 美国血液技术公司 | 从血液中富集免疫球蛋白的方法和装置 |
CN107964044B (zh) * | 2016-10-19 | 2021-11-19 | 无锡科捷诺生物科技有限责任公司 | 从乳样中纯化抗cd20单克隆抗体的方法 |
EP3769083A1 (en) | 2018-03-21 | 2021-01-27 | Waters Technologies Corporation | Non-antibody high-affinity-based sample preparation, sorbents, devices and methods |
EP3546475A1 (en) | 2018-03-27 | 2019-10-02 | Sanofi | Full flow-through process for purifying recombinant proteins |
US20210380638A1 (en) * | 2018-12-21 | 2021-12-09 | WuXi Biologics Ireland Limited | A method for improving aggregate removal by Protein A chromatography |
FR3099066B1 (fr) * | 2019-07-26 | 2021-08-13 | Novasep Process | Procédé de purification d’une substance cible avec inactivation virale |
TW202128264A (zh) * | 2019-09-25 | 2021-08-01 | 瑞士商赫孚孟拉羅股份公司 | 使用經預測之溶離緩衝鹽濃度的陽離子層析法 |
CA3156649A1 (en) * | 2019-10-04 | 2021-04-08 | Merck Patent Gmbh | PROTEIN PURIFICATION AND VIRAL INACTIVATION |
CN110724204B (zh) * | 2019-11-18 | 2021-10-22 | 广东菲鹏制药股份有限公司 | Fc融合蛋白的纯化方法 |
CN113845562A (zh) * | 2020-06-28 | 2021-12-28 | 佛山汉腾生物科技有限公司 | 目的蛋白纯化方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4490937A (en) | 1981-12-07 | 1985-01-01 | Amcor Ltd. | Insect electrocution device |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5256694A (en) | 1984-09-22 | 1993-10-26 | Basf Aktiengesellschaft | Diarylacetylenes, their preparation and their use |
US5091178A (en) | 1986-02-21 | 1992-02-25 | Oncogen | Tumor therapy with biologically active anti-tumor antibodies |
US6054051A (en) | 1996-01-17 | 2000-04-25 | Genentech, Inc. | Tangential-flow filtration system |
AU2003265235A1 (en) | 2002-04-26 | 2003-12-19 | Genetech, Inc. | Non-affinity purification of proteins |
WO2004024752A1 (ja) * | 2002-09-11 | 2004-03-25 | Chugai Seiyaku Kabushiki Kaisha | タンパク質精製方法 |
GB0304576D0 (en) | 2003-02-28 | 2003-04-02 | Lonza Biologics Plc | Protein a chromatography |
US20080312425A1 (en) * | 2004-08-30 | 2008-12-18 | Lonza Biologics Plc. | Ion Exchange Chromatography and Purification of Antibodies |
EP2069387A4 (en) * | 2006-06-14 | 2011-02-02 | Glaxosmithkline Llc | METHODS OF PURIFYING ANTIBODIES USING HYDROXYAPATITE CERAMIC |
WO2008025748A1 (en) * | 2006-08-28 | 2008-03-06 | Ares Trading S.A. | Process for the purification of fc-containing proteins |
MX2009002013A (es) * | 2006-08-28 | 2009-03-09 | Ares Trading Sa | Proceso para la purificacion de proteinas de fusion fc. |
US8168185B2 (en) * | 2007-01-17 | 2012-05-01 | Merck Serono Sa | Process for the purification of anti CD-25 antibodies |
US9433922B2 (en) | 2007-08-14 | 2016-09-06 | Emd Millipore Corporation | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
US20090149638A1 (en) * | 2007-10-03 | 2009-06-11 | Ley Arthur C | Systems and methods for purifying proteins |
WO2009138484A2 (en) | 2008-05-15 | 2009-11-19 | Novo Nordisk A/S | Antibody purification process |
MX2011004201A (es) * | 2008-10-20 | 2011-05-24 | Abbott Lab | Desactivacion viral durante purificacion de anticuerpos. |
-
2010
- 2010-08-05 ES ES10807153T patent/ES2817802T3/es active Active
- 2010-08-05 JP JP2012523945A patent/JP5791602B2/ja not_active Expired - Fee Related
- 2010-08-05 US US12/851,082 patent/US8536316B2/en active Active
- 2010-08-05 KR KR1020127001161A patent/KR101415660B1/ko not_active Expired - Fee Related
- 2010-08-05 CN CN201710418825.9A patent/CN107188960A/zh active Pending
- 2010-08-05 CN CN201080035153.XA patent/CN102574911B/zh not_active Expired - Fee Related
- 2010-08-05 EP EP10807153.1A patent/EP2462157B1/en active Active
- 2010-08-05 WO PCT/US2010/044539 patent/WO2011017514A1/en active Application Filing
- 2010-08-05 IN IN338DEN2012 patent/IN2012DN00338A/en unknown
- 2010-08-05 SG SG2012001483A patent/SG177577A1/en unknown
-
2015
- 2015-05-01 JP JP2015093970A patent/JP6335838B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
SG177577A1 (en) | 2012-03-29 |
CN107188960A (zh) | 2017-09-22 |
EP2462157A4 (en) | 2012-12-26 |
JP5791602B2 (ja) | 2015-10-07 |
CN102574911A (zh) | 2012-07-11 |
JP2013501721A (ja) | 2013-01-17 |
KR20120089432A (ko) | 2012-08-10 |
EP2462157A1 (en) | 2012-06-13 |
CN102574911B (zh) | 2017-06-06 |
JP6335838B2 (ja) | 2018-05-30 |
ES2817802T3 (es) | 2021-04-08 |
EP2462157B1 (en) | 2020-06-17 |
WO2011017514A1 (en) | 2011-02-10 |
US20110065901A1 (en) | 2011-03-17 |
KR101415660B1 (ko) | 2014-07-16 |
JP2015157846A (ja) | 2015-09-03 |
US8536316B2 (en) | 2013-09-17 |
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