IN184142B - - Google Patents

Info

Publication number
IN184142B
IN184142B IN2350MA1997A IN184142B IN 184142 B IN184142 B IN 184142B IN 2350MA1997 A IN2350MA1997 A IN 2350MA1997A IN 184142 B IN184142 B IN 184142B
Authority
IN
India
Prior art keywords
diastereomer
optically active
active form
complex
enantiomer
Prior art date
Application number
Other languages
English (en)
Inventor
Ton Rene Vries
Hans Wijnberg
Erik Vanechten
Lumbertus Albregt Hulshof
Quirinus Bernardus Broxterman
Original Assignee
Dsm Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Nv filed Critical Dsm Nv
Publication of IN184142B publication Critical patent/IN184142B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/023Preparation; Separation; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/80Preparation of compounds containing amino groups bound to a carbon skeleton by photochemical reactions; by using free radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30Preparation of optical isomers
    • C07C227/34Preparation of optical isomers by separation of optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/32Separation; Purification; Stabilisation; Use of additives
    • C07C253/34Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574Esters of oxyacids of phosphorus
    • C07F9/65742Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IN2350MA1997 1996-10-23 1997-10-20 IN184142B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL1004346A NL1004346C2 (nl) 1996-10-23 1996-10-23 Werkwijze voor het scheiden van een mengsel van enantiomeren in een geschikt oplosmiddel.

Publications (1)

Publication Number Publication Date
IN184142B true IN184142B (de) 2000-06-17

Family

ID=19763731

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2350MA1997 IN184142B (de) 1996-10-23 1997-10-20

Country Status (11)

Country Link
US (1) US6235927B1 (de)
EP (1) EP0838448B1 (de)
JP (1) JPH10245368A (de)
CN (1) CN1182068A (de)
AT (1) ATE264826T1 (de)
CA (1) CA2218804A1 (de)
DE (1) DE69728730T9 (de)
IL (1) IL122012A (de)
IN (1) IN184142B (de)
NL (1) NL1004346C2 (de)
NO (1) NO974779L (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6365756B1 (en) * 1998-02-20 2002-04-02 Fine Chemical Corporation Limited Process for the production of optically enriched (R)- or (S)-albuterol
US6713627B2 (en) 1998-03-13 2004-03-30 Aventis Pharmaceuticals Inc. Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
NL1008911C2 (nl) * 1998-04-17 1999-10-19 Dsm Nv Werkwijze voor het verhogen van de enantiomere overmaat van een chirale verbinding.
EP1034826A1 (de) * 1999-03-05 2000-09-13 Reuter Chemische Apparatebau Co-Kristallisationsverfahren
NL1012865C2 (nl) * 1999-08-19 2001-02-20 Dsm Nv 1-Fenyl-3-oxopropaan-1-sulfonzuren en -sulfonaten en zuivere enantiomeren daarvan.
WO2001030763A1 (en) 1999-10-22 2001-05-03 Takeda Chemical Industries, Ltd. Process for producing optically active naphthalene derivative and optical resolver therefor
US7666588B2 (en) * 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
JP2005104895A (ja) * 2003-09-30 2005-04-21 Nippon Kayaku Co Ltd 光学活性なアミノアルコール化合物の製造法
CA2547733C (en) * 2003-12-10 2009-09-08 Degussa Ag Process for the preparation of enantiomerically enriched amino acids
EP1720861A2 (de) 2004-02-25 2006-11-15 Eli Lilly And Company Antagonisten des histamin-h3-rezeptors, herstellung und therapeutische anwendungen
WO2006006071A1 (en) * 2004-07-07 2006-01-19 Pfizer Products Inc. Resolution of an aryl-fused azapolycyclic compound
US20080262089A1 (en) * 2005-05-04 2008-10-23 Medichem, S.A. Process for the Preparation of Tamsulosin
MX2007016216A (es) 2005-07-01 2008-03-11 Lilly Co Eli Agenes del receptor de histamina h3, preparacion y usos terapeuticos.
DK1951658T3 (da) 2005-11-17 2012-10-15 Lilly Co Eli Glucagonreceptorantagonister, fremstilling og terapeutiske anvendelser
PT1951659E (pt) 2005-11-18 2010-09-10 Lilly Co Eli Antagonistas do receptor do glucagon, preparação e utilizações terapêuticas
UA99284C2 (ru) 2007-05-11 2012-08-10 Елі Ліллі Енд Компані ИНГИБИТОРЫ р70 S6-КИНАЗЫ
HRP20160318T1 (hr) * 2008-07-29 2016-05-06 Poxel Postupak izolacije enantiomernih komponenti iz smjesa enantiomera pomoću kristalizacije kontrolirane veličinom čestica
AR075988A1 (es) 2009-04-09 2011-05-11 Lilly Co Eli Compuesto de piridiloxi - pirrolidina inhibidor de recaptacion de serotonina y norepinefrina, composicion farmaceutica que lo comprende y su uso para la manufactura de un medicamento util para el tratamiento de dolor cronico
AU2010310786B2 (en) 2009-10-23 2014-03-27 Eli Lilly And Company AKT inhibitors
CN101792398B (zh) * 2010-03-09 2013-06-26 河北科技大学 一种拆分法制备光学纯对羟基苯甘氨酸的方法
CN104876856B (zh) * 2015-05-05 2017-11-21 河北凯力昂生物科技有限公司 一种拆分法制备(r)‑(+)‑3‑氨基哌啶二盐酸盐的方法
CN104829459B (zh) * 2015-05-06 2017-05-24 河北凯力昂生物科技有限公司 一种拆分法制备(r)‑(+)‑1‑萘乙胺的方法
KR102565407B1 (ko) * 2016-01-04 2023-08-10 (주)아모레퍼시픽 극성 비양자성 용매를 이용한 n-[4-(1-아미노에틸)-페닐]-술폰아미드 유도체의 카이랄 분할 방법
CN108658784B (zh) * 2018-04-26 2020-12-18 联化科技股份有限公司 (r)-1-(4-甲基苯基)乙胺的合成方法
CN109485561A (zh) * 2018-11-23 2019-03-19 江苏颖盛化工有限公司 一种dl-萘普生的合成工艺
CA3154610A1 (en) * 2019-10-16 2021-04-22 Rakesh Ramesh GANORKAR An industrial process for resolution of chlocyphos
CN119487009A (zh) * 2022-07-14 2025-02-18 株式会社吴羽 三唑衍生物的对映异构体(r)构型的制造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB656500A (en) * 1947-10-24 1951-08-22 Sterling Drug Inc Improvements in or relating to the preparation of l-arterenol and l-arterenol so prepared
US3862985A (en) * 1971-07-28 1975-01-28 Allied Chem Resolution of lysineamide
EP0174358A1 (de) * 1984-03-01 1986-03-19 ALKALOIDA VEGYéSZETI GYáR Neue diateromersalze von phenylalanin sowie n-acyl abkömmlinge davon und verfahren zum trennen des optisch aktiven phenylalanins und dessen n-acyl abkömmlings

Also Published As

Publication number Publication date
EP0838448B1 (de) 2004-04-21
JPH10245368A (ja) 1998-09-14
DE69728730T9 (de) 2005-09-08
CN1182068A (zh) 1998-05-20
IL122012A0 (en) 1998-03-10
CA2218804A1 (en) 1998-04-23
NO974779L (no) 1998-04-24
NO974779D0 (no) 1997-10-16
EP0838448A1 (de) 1998-04-29
IL122012A (en) 2001-08-26
DE69728730D1 (de) 2004-05-27
US6235927B1 (en) 2001-05-22
NL1004346C2 (nl) 1998-04-24
ATE264826T1 (de) 2004-05-15
DE69728730T2 (de) 2005-03-31

Similar Documents

Publication Publication Date Title
IL122012A0 (en) Process for the separation of a mixture of enantiomers
DE69033355D1 (de) Imidazochinoxalinone, ihre Azaanaloge und Verfahren zu ihrer Herstellung
DE69133576D1 (de) Verfahren zur Herstellung von Enantiomerisch reine Beta-D-Dioxolan-Nukleoside
GB2209939B (en) The use of 13,14-dihydro-15-keto-prostaglandins as ocular hypotensive agents
BR9509406A (pt) Processo para a preparação de 4a,5,9,10,11,12,-hedaxidro-6h-benzofuro(3a,3,2,-ef) [2] benzazepina
EP0552041A3 (en) Enzymatic processes for resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
CA2245768A1 (en) Methods for treating emesis and central nervous system disorders using optically pure (+) norcisapride
MX209701B (es) Proceso para la preparacion de d-treo-(r,r)-metil fenidato y recirculacion de enantiomeros no deseados a traves de epimerizacion.
EP0671206A3 (de) Verfahren zur Herstellung von Mikrokapseln.
IT8922075A0 (it) Processo per l'inversione stereochimica di (2s,3s)-2-ammino-3-fenil-1 ,3-propandioli nei corrispondenti enantiomeri (2r,3r)
DE69735583D1 (de) Semisynthetisches verfahren zur herstellung von didemninanalogen
BG104240A (en) Methods and compositions for treating pulmonary disorders using optically pure (s)-salmeterol
DE69300551D1 (de) Verfahren zur Herstellung von (3R,4R)-3-Hydroxy-4-Hydroxymethyl-4-Butanolid.
DE69410222D1 (de) Verfahren zur Herstellung von optisch aktiven Erythro-3-amino-1,2-epoxy-Verbindungen
DK582083A (da) 4,7-dihydropyrazol(3,4-b)pyridin-5-karboxylsyrederivater
DE3855002D1 (de) Verfahren zur Herstellung von Dodecahydro-3a,6,6,9a-tetramethylnaphto(2,1-b)furan
CA2004554A1 (en) Novel(-)-2-pyrazoline compound, optical resolution of the same, and therapeutic agent for cerebrovascular disorders containing the same as effective ingredient
NO178096C (no) Fremgangsmåte for fremstilling av et transdermalt leveringssystem for en farmasöytisk aktiv forbindelse
EP0474250A3 (en) Enzymatic process for separating the optical isomers of racemic 1,2-diols
NO177264C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive, kondenserte benzazepiner, samt forbindelser for anvendelse som mellomprodukter ved analogifremgangsmåten
DE69735977D1 (de) Einarbeitung von aromatischen polycyclischen Verbindungen während Chinacridonherstellungsverfahren
DE69006659D1 (de) Verfahren zur Herstellung von 1,1'-Oxybis(3-nitro-5-trifluormethyl)benzol.
BR9006199A (pt) Processo para preparacao de um composto moluscicida
DE59812729D1 (de) Verfahren zur Herstellung von 1,3-Dioxanverbindungen
DE59005407D1 (de) Verfahren zur Herstellung von faserreaktiven Formazanverbindungen.