IN181540B - - Google Patents
Info
- Publication number
- IN181540B IN181540B IN46CA1997A IN181540B IN 181540 B IN181540 B IN 181540B IN 46CA1997 A IN46CA1997 A IN 46CA1997A IN 181540 B IN181540 B IN 181540B
- Authority
- IN
- India
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19601744A DE19601744C2 (de) | 1996-01-19 | 1996-01-19 | Verfahren zur Herstellung der Enantiomeren von O-Demethyltramadol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN181540B true IN181540B (en, 2012) | 1998-07-11 |
Family
ID=7783111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN46CA1997 IN181540B (en, 2012) | 1996-01-19 | 1997-01-09 |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US5728885A (en, 2012) |
| EP (1) | EP0786450B1 (en, 2012) |
| JP (1) | JPH09216857A (en, 2012) |
| KR (1) | KR100507396B1 (en, 2012) |
| CN (1) | CN1073085C (en, 2012) |
| AR (1) | AR005390A1 (en, 2012) |
| AT (1) | ATE191454T1 (en, 2012) |
| AU (1) | AU705195B2 (en, 2012) |
| BR (1) | BR9700079A (en, 2012) |
| CA (1) | CA2195372C (en, 2012) |
| CO (1) | CO4520186A1 (en, 2012) |
| CZ (1) | CZ292427B6 (en, 2012) |
| DE (2) | DE19601744C2 (en, 2012) |
| DK (1) | DK0786450T3 (en, 2012) |
| ES (1) | ES2147341T3 (en, 2012) |
| GR (1) | GR3033390T3 (en, 2012) |
| HU (1) | HU223661B1 (en, 2012) |
| IL (1) | IL120029A (en, 2012) |
| IN (1) | IN181540B (en, 2012) |
| MY (1) | MY116593A (en, 2012) |
| NO (1) | NO306943B1 (en, 2012) |
| NZ (1) | NZ299998A (en, 2012) |
| PE (1) | PE29998A1 (en, 2012) |
| PL (1) | PL187373B1 (en, 2012) |
| PT (1) | PT786450E (en, 2012) |
| RU (1) | RU2185371C2 (en, 2012) |
| SI (1) | SI0786450T1 (en, 2012) |
| SK (1) | SK282629B6 (en, 2012) |
| UA (1) | UA45342C2 (en, 2012) |
| UY (1) | UY24438A1 (en, 2012) |
| ZA (1) | ZA97367B (en, 2012) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19712398A1 (de) * | 1997-03-25 | 1998-10-01 | Gruenenthal Gmbh | Orale Anwendung von (+)-0-Demethyltramadol als Schmerzmittel |
| PE20010623A1 (es) | 1999-10-05 | 2001-07-07 | Gruenenthal Chemie | Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria |
| AU1164601A (en) * | 1999-11-09 | 2001-06-06 | Darwin Discovery Limited | Therapeutic use and formulation |
| DE10049483A1 (de) | 2000-09-29 | 2002-05-02 | Gruenenthal Gmbh | Substituierte 1-Aminobutan-3-ol-Derivate |
| DE10108123A1 (de) * | 2001-02-21 | 2002-10-02 | Gruenenthal Gmbh | Wirkstoffkombination |
| DE10108122A1 (de) | 2001-02-21 | 2002-10-02 | Gruenenthal Gmbh | Arzneimittel auf Basis von Tramadol |
| US20050176790A1 (en) | 2001-02-28 | 2005-08-11 | Johannes Bartholomaus | Pharmaceutical salts |
| DE10109763A1 (de) * | 2001-02-28 | 2002-09-05 | Gruenenthal Gmbh | Pharmazeutische Salze |
| DK1397126T5 (da) | 2001-03-16 | 2007-05-21 | Dmi Biosciences Inc | Anvendelse af tramadol til forsinkelse af ejakulation |
| US6649783B2 (en) * | 2001-10-03 | 2003-11-18 | Euro-Celtique, S.A. | Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols |
| AU2002364517A1 (en) | 2001-11-30 | 2003-06-17 | Sepracor Inc. | Tramadol analogs and uses thereof |
| US20040248979A1 (en) * | 2003-06-03 | 2004-12-09 | Dynogen Pharmaceuticals, Inc. | Method of treating lower urinary tract disorders |
| DE102005033732B4 (de) * | 2005-05-27 | 2014-02-13 | Grünenthal GmbH | Trennung stereoisomerer N,N-Dialkylamino-2-alkyl-3-hydroxy-3-phenyl-alkane |
| EP1785412A1 (en) * | 2005-11-14 | 2007-05-16 | IPCA Laboratories Limited | Tramadol recovery process |
| NZ579170A (en) | 2007-02-12 | 2012-05-25 | Dmi Biosciences Inc | Reducing side effects of tramadol |
| KR20090121315A (ko) * | 2007-02-12 | 2009-11-25 | 디엠아이 바이오사이언시스 인코포레이티드 | 조루 및 발기부전을 동시에 치료하는 방법 |
| US20110251286A1 (en) * | 2010-03-10 | 2011-10-13 | Gruenenthal Gmbh | Crystalline salts and/or co-crystals of O-desmethyltramadol |
| EP2383255A1 (en) | 2010-04-28 | 2011-11-02 | Lacer, S.A. | New compounds, synthesis and use thereof in the treatment of pain |
| EP2530072A1 (en) | 2011-06-03 | 2012-12-05 | Lacer, S.A. | New compounds, synthesis and use thereof in the treatment of pain |
| US10702485B2 (en) | 2011-07-09 | 2020-07-07 | Syntrix Biosystems Inc. | Compositions and methods for overcoming resistance to tramadol |
| WO2019053494A1 (en) | 2017-09-18 | 2019-03-21 | R L Fine Chem Private Limited | PROCESS FOR THE PREPARATION OF O-DESMETHYLTRAMADOL AND SALTS THEREOF |
| US11000488B2 (en) | 2019-03-22 | 2021-05-11 | Syntrix Biosystems Inc. | Treating pain using desmetramadol |
| CN118108610B (zh) * | 2024-04-30 | 2025-01-10 | 山东新华制药股份有限公司 | 盐酸去甲曲马多的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1518663A1 (de) * | 1965-08-02 | 1969-12-18 | Gruenenthal Chemie | Basisch substituierte Cycloalken-derivate und Verfahren zu ihrer Herstellung |
| US3652589A (en) * | 1967-07-27 | 1972-03-28 | Gruenenthal Chemie | 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols |
| US3652289A (en) * | 1970-07-20 | 1972-03-28 | Eastman Kodak Co | Silver halide emulsions and elements comprising trimethine hemioxonal dyes |
| NO300197B1 (no) | 1991-09-06 | 1997-04-28 | Mcneilab Inc | Preparater omfattende tramadol og et opioid |
| ES2120451T7 (es) | 1991-09-06 | 2009-11-05 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Composicion que comprende un compuesto de tramadol y acetaminofeno, y su uso. |
| JPH06122686A (ja) * | 1992-10-12 | 1994-05-06 | Fujisawa Pharmaceut Co Ltd | ラセミ体の光学分割法 |
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1996
- 1996-01-19 DE DE19601744A patent/DE19601744C2/de not_active Expired - Fee Related
- 1996-12-18 PE PE1996000931A patent/PE29998A1/es not_active Application Discontinuation
- 1996-12-21 EP EP96120727A patent/EP0786450B1/de not_active Expired - Lifetime
- 1996-12-21 PT PT96120727T patent/PT786450E/pt unknown
- 1996-12-21 SI SI9630187T patent/SI0786450T1/xx unknown
- 1996-12-21 DE DE59604885T patent/DE59604885D1/de not_active Expired - Lifetime
- 1996-12-21 AT AT96120727T patent/ATE191454T1/de active
- 1996-12-21 DK DK96120727T patent/DK0786450T3/da active
- 1996-12-21 ES ES96120727T patent/ES2147341T3/es not_active Expired - Lifetime
- 1996-12-23 NZ NZ299998A patent/NZ299998A/en not_active IP Right Cessation
- 1996-12-30 CO CO96068522A patent/CO4520186A1/es unknown
- 1996-12-30 MY MYPI96005545A patent/MY116593A/en unknown
-
1997
- 1997-01-07 AR ARP970100068A patent/AR005390A1/es active IP Right Grant
- 1997-01-09 IN IN46CA1997 patent/IN181540B/en unknown
- 1997-01-10 UY UY24438A patent/UY24438A1/es not_active IP Right Cessation
- 1997-01-10 BR BR9700079A patent/BR9700079A/pt not_active Application Discontinuation
- 1997-01-16 HU HU9700140A patent/HU223661B1/hu not_active IP Right Cessation
- 1997-01-16 ZA ZA97367A patent/ZA97367B/xx unknown
- 1997-01-17 CN CN97102072A patent/CN1073085C/zh not_active Expired - Fee Related
- 1997-01-17 PL PL97318002A patent/PL187373B1/pl not_active IP Right Cessation
- 1997-01-17 UA UA97010174A patent/UA45342C2/uk unknown
- 1997-01-17 CA CA002195372A patent/CA2195372C/en not_active Expired - Fee Related
- 1997-01-17 SK SK67-97A patent/SK282629B6/sk not_active IP Right Cessation
- 1997-01-17 JP JP9006904A patent/JPH09216857A/ja not_active Ceased
- 1997-01-17 KR KR1019970001204A patent/KR100507396B1/ko not_active Expired - Fee Related
- 1997-01-17 US US08/784,078 patent/US5728885A/en not_active Expired - Lifetime
- 1997-01-17 IL IL12002997A patent/IL120029A/xx not_active IP Right Cessation
- 1997-01-17 AU AU12216/97A patent/AU705195B2/en not_active Ceased
- 1997-01-17 RU RU97100984/04A patent/RU2185371C2/ru not_active IP Right Cessation
- 1997-01-17 NO NO970212A patent/NO306943B1/no not_active IP Right Cessation
- 1997-01-17 CZ CZ1997157A patent/CZ292427B6/cs not_active IP Right Cessation
-
2000
- 2000-05-09 GR GR20000401077T patent/GR3033390T3/el unknown