IN167550B - - Google Patents

Info

Publication number
IN167550B
IN167550B IN556/MAS/88A IN556MA1988A IN167550B IN 167550 B IN167550 B IN 167550B IN 556MA1988 A IN556MA1988 A IN 556MA1988A IN 167550 B IN167550 B IN 167550B
Authority
IN
India
Application number
IN556/MAS/88A
Other languages
English (en)
Inventor
Fernandez Torija Carlos
Alvaro Caliano Ramos Joaquin
Original Assignee
Delagrange Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delagrange Lab filed Critical Delagrange Lab
Publication of IN167550B publication Critical patent/IN167550B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IN556/MAS/88A 1987-08-03 1988-08-03 IN167550B (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87401799A EP0302980B1 (fr) 1987-08-03 1987-08-03 1,4-Dihydropyridines, leur procédé de préparation et leur application comme médicaments

Publications (1)

Publication Number Publication Date
IN167550B true IN167550B (no) 1990-11-10

Family

ID=8198243

Family Applications (1)

Application Number Title Priority Date Filing Date
IN556/MAS/88A IN167550B (no) 1987-08-03 1988-08-03

Country Status (34)

Country Link
US (1) US4952592A (no)
EP (1) EP0302980B1 (no)
JP (1) JPH0733383B2 (no)
KR (1) KR960001724B1 (no)
CN (1) CN1038587C (no)
AT (1) ATE61588T1 (no)
BE (1) BE1001055A4 (no)
CA (2) CA1306261C (no)
CH (1) CH675999A5 (no)
CZ (1) CZ282077B6 (no)
DD (1) DD282008A5 (no)
DE (2) DE3768658D1 (no)
DK (1) DK430288A (no)
ES (1) ES2007543A6 (no)
FI (1) FI91406C (no)
GB (1) GB2208861B (no)
GR (2) GR880100507A (no)
HU (1) HU204523B (no)
IE (1) IE60358B1 (no)
IL (1) IL87321A (no)
IN (1) IN167550B (no)
IS (1) IS1549B (no)
IT (1) IT1235013B (no)
LU (1) LU87297A1 (no)
MA (1) MA21344A1 (no)
NO (1) NO170934C (no)
NZ (1) NZ225661A (no)
PH (1) PH25645A (no)
PT (1) PT88173B (no)
RU (1) RU2036922C1 (no)
SK (1) SK278775B6 (no)
TN (1) TNSN88081A1 (no)
YU (1) YU46547B (no)
ZA (1) ZA885684B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242933A (en) * 1990-07-10 1993-09-07 Adir Et Compagnie Piperidine, tetrahydropyridine and pyrrolidine compounds
ES2166462T3 (es) * 1995-08-02 2002-04-16 Smithkline Beecham Corp Antagonistas del receptor de la endotelina.
ES2287110T3 (es) * 2000-04-11 2007-12-16 Sankyo Company, Limited Composicion farmaceutica estabilizada que contiene un bloqueador de calcio consistente en azelnidipina.
ES2362998T3 (es) 2002-08-19 2011-07-18 Pfizer Inc. Terapia de combinación para enfermedades hiperproliferativas.
BRPI0513866A (pt) * 2004-07-26 2008-05-20 Cotherix Inc composição, micropartìculas, método para o tratamento da hipertensão pulmonar, e dispositivo de inalação
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
EP1951253A2 (en) 2005-10-26 2008-08-06 Cotherix, Inc. Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
TW200736245A (en) * 2005-11-29 2007-10-01 Sankyo Co Acid addition salts of optically active dihydropyridine derivatives
TW200806648A (en) * 2005-11-29 2008-02-01 Sankyo Co Acid addition salts of dihydropyridine derivatives
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
EP2986599A1 (en) 2013-04-17 2016-02-24 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CA3125765A1 (en) 2019-01-18 2020-07-23 Astrazeneca Ab Pcsk9 inhibitors and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3441648A (en) * 1967-02-07 1969-04-29 Smithkline Corp Compositions and methods for lowering blood pressure with 1,4-dihydropyridines
US4031104A (en) * 1972-04-18 1977-06-21 Bayer Aktiengesellschaft 1,4-Dihydropyridine carboxylic acid esters
JPS5978186A (ja) * 1982-10-27 1984-05-04 Yoshitomi Pharmaceut Ind Ltd 1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
ES531033A0 (es) * 1984-03-27 1985-09-01 Inst Investigacion Desarrollo Un procedimiento para la preparacion de nuevas 1,4-dihidropirinas-4-(polioxialquilfenil)-sustituidas
JPH068294B2 (ja) * 1985-02-26 1994-02-02 富山化学工業株式会社 新規な1,4−ジヒドロピリジン誘導体およびその塩
EP0174131A3 (en) * 1984-09-01 1989-06-07 FISONS plc Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them
JPH01207267A (ja) * 1987-03-05 1989-08-21 Yamanouchi Pharmaceut Co Ltd ピリジン誘導体及び該化合物を含有する肝疾患治療剤

Also Published As

Publication number Publication date
GB8818356D0 (en) 1988-09-07
GB2208861B (en) 1991-07-17
IE882364L (en) 1989-02-03
NZ225661A (en) 1990-08-28
NO170934C (no) 1992-12-30
RU2036922C1 (ru) 1995-06-09
IL87321A0 (en) 1989-01-31
NO883406D0 (no) 1988-08-01
FI883603A (fi) 1989-02-04
CN1031531A (zh) 1989-03-08
PH25645A (en) 1991-08-21
DD282008A5 (de) 1990-08-29
IS3378A7 (is) 1989-02-04
GR880100507A (el) 1989-05-25
HU204523B (en) 1992-01-28
FI883603A0 (fi) 1988-08-01
ZA885684B (en) 1989-04-26
ES2007543A6 (es) 1989-06-16
FI91406B (fi) 1994-03-15
IS1549B (is) 1994-06-08
US4952592A (en) 1990-08-28
NO170934B (no) 1992-09-21
CZ282077B6 (cs) 1997-05-14
IL87321A (en) 1993-04-04
DK430288D0 (da) 1988-08-02
GB2208861A (en) 1989-04-19
YU46547B (sh) 1993-11-16
YU147088A (en) 1990-04-30
GR3001984T3 (en) 1992-11-23
BE1001055A4 (fr) 1989-06-20
KR960001724B1 (ko) 1996-02-03
CN1038587C (zh) 1998-06-03
HUT54142A (en) 1991-01-28
CA1306261C (fr) 1992-08-11
IE60358B1 (en) 1994-06-29
SK541388A3 (en) 1998-02-04
EP0302980B1 (fr) 1991-03-13
JPH01294675A (ja) 1989-11-28
ATE61588T1 (de) 1991-03-15
KR890003743A (ko) 1989-04-17
PT88173B (pt) 1995-03-01
CA1306262C (fr) 1992-08-11
FI91406C (fi) 1994-06-27
DE3825962A1 (de) 1989-02-16
CH675999A5 (en) 1990-11-30
AU2033088A (en) 1989-02-09
MA21344A1 (fr) 1989-04-01
NO883406L (no) 1989-02-06
DK430288A (da) 1989-02-03
PT88173A (pt) 1989-06-30
EP0302980A1 (fr) 1989-02-15
DE3768658D1 (de) 1991-04-18
IT8848259A0 (it) 1988-08-02
LU87297A1 (fr) 1989-02-02
CZ541388A3 (en) 1997-01-15
TNSN88081A1 (fr) 1990-07-10
IT1235013B (it) 1992-06-16
AU606441B2 (en) 1991-02-07
SK278775B6 (sk) 1998-02-04
JPH0733383B2 (ja) 1995-04-12

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