IL97538A - Multilayer liposomes containing guanidino aminoglycosides and their preparation - Google Patents

Multilayer liposomes containing guanidino aminoglycosides and their preparation

Info

Publication number
IL97538A
IL97538A IL9753887A IL9753887A IL97538A IL 97538 A IL97538 A IL 97538A IL 9753887 A IL9753887 A IL 9753887A IL 9753887 A IL9753887 A IL 9753887A IL 97538 A IL97538 A IL 97538A
Authority
IL
Israel
Prior art keywords
liposomes
aminoglycoside
lipid
nonphosphate
aminoglycosides
Prior art date
Application number
IL9753887A
Other languages
English (en)
Hebrew (he)
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27130236&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL97538(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Priority claimed from IL81247A external-priority patent/IL81247A0/xx
Publication of IL97538A publication Critical patent/IL97538A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL9753887A 1986-12-23 1987-01-13 Multilayer liposomes containing guanidino aminoglycosides and their preparation IL97538A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94639886A 1986-12-23 1986-12-23
US94639186A 1986-12-23 1986-12-23
IL81247A IL81247A0 (fr) 1987-01-13 1987-01-13

Publications (1)

Publication Number Publication Date
IL97538A true IL97538A (en) 1995-03-15

Family

ID=27130236

Family Applications (2)

Application Number Title Priority Date Filing Date
IL9753887A IL97538A (en) 1986-12-23 1987-01-13 Multilayer liposomes containing guanidino aminoglycosides and their preparation
IL97538A IL97538A0 (en) 1986-12-23 1991-03-13 Liposomes containing an aminoglycoside salt and their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL97538A IL97538A0 (en) 1986-12-23 1991-03-13 Liposomes containing an aminoglycoside salt and their preparation

Country Status (8)

Country Link
EP (3) EP0498471B1 (fr)
JP (1) JP2528153B2 (fr)
AT (2) ATE87503T1 (fr)
AU (1) AU609711B2 (fr)
CA (1) CA1314481C (fr)
DE (3) DE3785198T3 (fr)
IL (2) IL97538A (fr)
WO (1) WO1988004573A1 (fr)

Families Citing this family (46)

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US4920016A (en) * 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
CA1340241C (fr) * 1988-06-08 1998-12-15 Fountain Pharmaceuticals, Inc. Methode pour l'obtention de microvehicules, avec dilution dans un solvant
US5269979A (en) * 1988-06-08 1993-12-14 Fountain Pharmaceuticals, Inc. Method for making solvent dilution microcarriers
BE1001869A3 (fr) * 1988-10-12 1990-04-03 Franz Legros Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine.
US5843473A (en) * 1989-10-20 1998-12-01 Sequus Pharmaceuticals, Inc. Method of treatment of infected tissues
CA2046997C (fr) * 1990-07-16 2000-12-12 Hiroshi Kikuchi Liposomes
US6060080A (en) * 1990-07-16 2000-05-09 Daiichi Pharmaceutical Co., Ltd. Liposomal products
PT100486B (pt) * 1992-05-14 1999-07-30 Ineti Inst Nac Engenh E Tecnol Aminoglucosidos lipossomais com altas eficacia de encapsulacao e actividade terapeutica, nomeadamente a netilmicina, e processo para a sua preparcao
AU3244393A (en) * 1992-12-02 1994-06-22 Vestar, Inc. Antibiotic formulation and process
US5958449A (en) 1992-12-02 1999-09-28 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for bacterial infections
CN1040177C (zh) * 1993-04-23 1998-10-14 江苏省微生物研究所 一种含1-N-乙基庆大霉素C1a或其盐的药用制剂及制备方法
US5759571A (en) * 1993-05-11 1998-06-02 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for drug resistant infections
NZ276305A (en) * 1993-11-16 1997-10-24 Depotech Corp Controlled release vesicle compositions
US6613352B2 (en) 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
JP4677538B2 (ja) 2001-06-12 2011-04-27 ジョンズ ホプキンズ ユニヴァーシティ スクール オヴ メディシン 眼内薬物送達のためのリザーバデバイス
US20050085432A1 (en) * 2001-12-26 2005-04-21 Aviva Lapidot Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
SI2363114T1 (sl) * 2002-10-29 2015-07-31 Insmed Incorporated Zadržano sproščanje antiinfektivov
EP3718532A1 (fr) 2005-12-08 2020-10-07 Insmed Incorporated Compositions a base de lipide d'anti-infectieux pour traiter des infections pulmonaires
US20100196455A1 (en) 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
CN104887389B (zh) 2009-01-29 2017-06-23 弗赛特影像4股份有限公司 后段给药
CA2807535C (fr) 2010-08-05 2019-03-19 Forsight Vision4, Inc. Appareil d'injection et procede d'administration de medicament
PL2600812T3 (pl) 2010-08-05 2022-01-24 Forsight Vision4, Inc. Urządzenie do leczenia oczu
EP2600876B1 (fr) 2010-08-05 2015-04-29 Forsight Vision4, Inc. Procédés et appareils d'administration combinée de médicament
WO2012068549A2 (fr) 2010-11-19 2012-05-24 Forsight Vision4, Inc. Formulations d'agents thérapeutiques pour des dispositifs implantés
EP2726016B1 (fr) 2011-06-28 2023-07-19 ForSight Vision4, Inc. Un appareil pour collecter un échantillon de fluide à partir d'une chambre réservoir d'un dispositif thérapeutique pour l'oeil
EP2739252A4 (fr) 2011-08-05 2015-08-12 Forsight Vision4 Inc Administration de petites molécules à l'aide d'un dispositif thérapeutique implantable
WO2013040247A2 (fr) 2011-09-16 2013-03-21 Forsight Vision4, Inc. Appareil et procédés d'échange de fluides
US10010448B2 (en) 2012-02-03 2018-07-03 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
ES2969659T3 (es) 2012-05-21 2024-05-21 Insmed Inc Sistemas para el tratamiento de infecciones pulmonares
EP3581186A1 (fr) 2012-11-29 2019-12-18 Insmed Incorporated Formulations de vancomycine stabilisées
AU2014236455B2 (en) 2013-03-14 2018-07-12 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
JP6385423B2 (ja) 2013-03-28 2018-09-05 フォーサイト・ビジョン フォー・インコーポレーテッド 治療物質送達用の眼移植片
EP4122470B1 (fr) 2014-05-15 2024-03-20 Insmed Incorporated Méthodes de traitement d'infections pulmonaires mycobactériennes non-tuberculeuses
JP6581194B2 (ja) 2014-07-15 2019-09-25 フォーサイト・ビジョン フォー・インコーポレーテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ４， Ｉｎｃ． 眼用インプラント送達装置および方法
SG11201700943TA (en) 2014-08-08 2017-03-30 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
CN114587774B (zh) 2014-11-10 2024-07-19 弗赛特影像4股份有限公司 治疗眼睛的系统
WO2017087902A1 (fr) 2015-11-20 2017-05-26 Forsight Vision4, Inc. Structures poreuses pour dispositifs d'administration de médicament à libération prolongée
AR108177A1 (es) 2016-04-05 2018-07-25 Forsight Vision4 Inc Dispositivos de suministro de fármacos oculares implantables
CA3082891A1 (fr) 2017-11-21 2019-05-31 Forsight Vision4, Inc. Appareil d'echange de fluide pour systeme d'administration a port extensible et methodes d'utilisation
US11571386B2 (en) 2018-03-30 2023-02-07 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device

Family Cites Families (17)

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US3993754A (en) * 1974-10-09 1976-11-23 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome-encapsulated actinomycin for cancer chemotherapy
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
US4086257A (en) * 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
CH624011A5 (fr) * 1977-08-05 1981-07-15 Battelle Memorial Institute
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4397846A (en) * 1981-05-15 1983-08-09 Murray Weiner Storage-stable lipid vesicles and method of preparation
JPS59500952A (ja) * 1982-03-29 1984-05-31 ザ　リポソ−ム　カンパニ−、インコ−ポレ−テッド 安定なプルリラメラベシクル類
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
SU1123697A1 (ru) * 1982-08-18 1984-11-15 Всесоюзный научно-исследовательский институт фармации Способ получени липосомальной формы антибиотиков стрептомицинового р да
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
JPS59210013A (ja) * 1983-05-04 1984-11-28 Ajinomoto Co Inc 活性物質含有リポソ−ム
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
EP0153948A1 (fr) * 1983-08-31 1985-09-11 Diagraph Corporation Dispositif d'impression a jet d'encre
US4532089A (en) * 1984-01-14 1985-07-30 Northwestern University Method of preparing giant size liposomes
US4610868A (en) * 1984-03-20 1986-09-09 The Liposome Company, Inc. Lipid matrix carriers for use in drug delivery systems
JPH0655676B2 (ja) * 1984-07-26 1994-07-27 ザ リポソ−ム カンパニ−、インコ−ポレ−テツド 脂質小胞体中に含有された抗菌物質の混合物による抗菌活性の増高
JPH0680767A (ja) * 1992-09-03 1994-03-22 Matsushita Electric Ind Co Ltd 電子・電気機器用エポキシ樹脂組成物

Also Published As

Publication number Publication date
ATE87503T1 (de) 1993-04-15
WO1988004573A1 (fr) 1988-06-30
ATE141166T1 (de) 1996-08-15
EP0295248B2 (fr) 1999-04-28
CA1314481C (fr) 1993-03-16
IL97538A0 (en) 1992-06-21
DE3751871T4 (de) 1998-03-26
EP0498471A2 (fr) 1992-08-12
JP2528153B2 (ja) 1996-08-28
AU6934587A (en) 1988-07-15
DE3785198T3 (de) 1999-09-02
DE3785198T2 (de) 1993-07-15
AU609711B2 (en) 1991-05-09
EP0500143A2 (fr) 1992-08-26
EP0295248B1 (fr) 1993-03-31
EP0498471B1 (fr) 1996-08-14
DE3751871T2 (de) 1997-03-13
EP0500143A3 (en) 1993-03-03
EP0295248A4 (fr) 1988-12-19
DE3785198D1 (de) 1993-05-06
JPH01501619A (ja) 1989-06-08
EP0295248A1 (fr) 1988-12-21
DE3751871D1 (de) 1996-09-19
EP0498471A3 (en) 1993-03-03

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