IL95235A - PG031 protein and the process for its preparation - Google Patents

PG031 protein and the process for its preparation

Info

Publication number
IL95235A
IL95235A IL9523590A IL9523590A IL95235A IL 95235 A IL95235 A IL 95235A IL 9523590 A IL9523590 A IL 9523590A IL 9523590 A IL9523590 A IL 9523590A IL 95235 A IL95235 A IL 95235A
Authority
IL
Israel
Prior art keywords
protein
receptor
human
cells
dna
Prior art date
Application number
IL9523590A
Other languages
English (en)
Hebrew (he)
Other versions
IL95235A0 (en
Original Assignee
Kishimoto Tadamitsu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kishimoto Tadamitsu filed Critical Kishimoto Tadamitsu
Publication of IL95235A0 publication Critical patent/IL95235A0/xx
Publication of IL95235A publication Critical patent/IL95235A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL9523590A 1989-08-03 1990-07-30 PG031 protein and the process for its preparation IL95235A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20023089 1989-08-03
JP2140069A JP2898064B2 (ja) 1989-08-03 1990-05-31 ヒトgp130蛋白質

Publications (2)

Publication Number Publication Date
IL95235A0 IL95235A0 (en) 1991-06-10
IL95235A true IL95235A (en) 1995-11-27

Family

ID=26472699

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9523590A IL95235A (en) 1989-08-03 1990-07-30 PG031 protein and the process for its preparation

Country Status (10)

Country Link
US (1) US5132403A (de)
EP (1) EP0411946B1 (de)
JP (1) JP2898064B2 (de)
KR (1) KR0178384B1 (de)
AT (1) ATE147099T1 (de)
AU (1) AU635296B2 (de)
CA (1) CA2022610C (de)
DE (1) DE69029545T2 (de)
ES (1) ES2096580T3 (de)
IL (1) IL95235A (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262522A (en) * 1991-11-22 1993-11-16 Immunex Corporation Receptor for oncostatin M and leukemia inhibitory factor
DK0988871T3 (da) * 1991-12-18 2004-05-24 Icu Medical Inc Fremgangsmåde til overføring af fluid
JPH05304986A (ja) * 1992-04-28 1993-11-19 Tosoh Corp gp130蛋白質に対するモノクロ−ナル抗体
IT1261787B (it) * 1993-06-23 1996-06-03 Angeletti P Ist Richerche Bio Metodologia per la selezione di superagonisti, antagonisti e super- antagonisti di ormoni del cui complesso recettoriale fa parte gp 130.
US5891998A (en) * 1993-06-23 1999-04-06 Istituto Di Ricerche Di Biologica Molecolare P. Angeletti S.P.A. Interleukin-6 receptor agonists
US5783672A (en) 1994-05-26 1998-07-21 Immunex Corporation Receptor for oncostatin M
WO1996000462A1 (de) * 1994-06-23 1996-01-04 Elin Motoren Gesellschaft M.B.H Kühlung für einen motor
GB9419021D0 (en) 1994-09-21 1994-11-09 Applied Research Systems Therapeutic protein
ES2384222T3 (es) 1994-10-07 2012-07-02 Chugai Seiyaku Kabushiki Kaisha Inhibición del crecimiento anómalo de células sinoviales utilizando un antagonista de IL-6 como principio activo
JP3458512B2 (ja) 1995-02-23 2003-10-20 東ソー株式会社 骨密度の変動推定方法又は骨そしょう症の診断方法及びこれに用いる試薬キット
US5674995A (en) * 1995-06-07 1997-10-07 Gen-Probe Incorporated Oligonucleotides specific for cytokine signal transducer gp130 mRNA
US5747470A (en) * 1995-06-07 1998-05-05 Gen-Probe Incorporated Method for inhibiting cellular proliferation using antisense oligonucleotides to gp130 mRNA
WO1996040908A1 (en) * 1995-06-07 1996-12-19 Gen-Probe Incorporated OLIGONUCLEOTIDES SPECIFIC FOR CYTOKINE SIGNAL TRANSDUCER gp130 mRNA
CA2237114A1 (en) * 1995-11-07 1997-05-15 Kaneka Corporation Autoantigens
EP2322216A1 (de) 1997-03-21 2011-05-18 Chugai Seiyaku Kabushiki Kaisha Präventives oder therapeutisches Mittel mit einem IL-6-Antagonisten als Wirkstoff für durch sensibilisierte T-Zellen vermittelte Erkrankungen
EP2325316B8 (de) 1999-06-02 2017-04-19 Chugai Seiyaku Kabushiki Kaisha Neues Hämopoietin Receptorprotein, NR10
AU7078200A (en) 1999-08-27 2001-03-26 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Polypeptides, comprising il-6 ligand-binding receptor domains and related nucleic acids, antibodies, compositions, and methods of use
AU7445900A (en) 1999-09-27 2001-04-30 Chugai Seiyaku Kabushiki Kaisha Novel hemopoietin receptor protein, nr12
US7175988B2 (en) * 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
UA80091C2 (en) 2001-04-02 2007-08-27 Chugai Pharmaceutical Co Ltd Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
GB0210539D0 (en) * 2002-05-08 2002-06-19 Univ Edinburgh Control of es cell self renewal and lineage specification, and medium therefor
GB2401040A (en) 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
WO2007043641A1 (ja) 2005-10-14 2007-04-19 Fukuoka University 膵島移植における移植膵島障害抑制剤
JP4837358B2 (ja) * 2005-10-19 2011-12-14 株式会社野村工電社 ボトル飲用水充填装置
AR058135A1 (es) 2005-10-21 2008-01-23 Chugai Pharmaceutical Co Ltd Agentes para el tratamiento de cardiopatias
AR057582A1 (es) 2005-11-15 2007-12-05 Nat Hospital Organization Agentes para suprimir la induccion de linfocitos t citotoxicos
TW200803894A (en) 2005-11-25 2008-01-16 Univ Keio Prostate cancer therapeutic agents
AU2007208678B2 (en) 2006-01-27 2013-01-10 Chugai Seiyaku Kabushiki Kaisha Therapeutic agents for diseases involving choroidal neovascularization
JP5754875B2 (ja) 2006-04-07 2015-07-29 国立大学法人大阪大学 筋再生促進剤
ES2429407T3 (es) 2006-06-08 2013-11-14 Chugai Seiyaku Kabushiki Kaisha Agente preventivo o remedio para enfermedades inflamatorias
WO2008020079A1 (en) 2006-08-18 2008-02-21 Ablynx N.V. Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling
TWI438208B (zh) 2007-01-23 2014-05-21 中外製藥股份有限公司 抑制慢性排斥反應之藥劑
US20080283557A1 (en) * 2007-05-17 2008-11-20 Julianne Desautels Spout for food stuff container
CA2708065C (en) 2007-12-05 2015-02-24 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for pruritus
CA2728243C (en) 2008-06-05 2020-03-10 Chugai Seiyaku Kabushiki Kaisha Il-6 inhibitor for suppressing neuroinvasion in pancreatic cancer
EP2226633A1 (de) * 2009-03-06 2010-09-08 Charité - Universitätsmedizin Berlin Verwendungen und Verfahren zur Identifikation einer zytoprotektiven Verbindung mit gp130 oder LIFRalpha
WO2010115995A2 (en) 2009-04-10 2010-10-14 Ablynx Nv Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders
NZ595461A (en) 2009-04-10 2013-01-25 Ablynx Nv Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders
WO2011149046A1 (ja) 2010-05-28 2011-12-01 独立行政法人国立がん研究センター 膵癌治療剤
WO2011149051A1 (ja) 2010-05-28 2011-12-01 中外製薬株式会社 抗腫瘍t細胞応答増強剤
WO2013041722A1 (en) 2011-09-23 2013-03-28 Ablynx Nv Prolonged inhibition of interleukin-6 mediated signaling
US10782290B2 (en) 2013-06-11 2020-09-22 National Center Of Neurology And Psychiatry Method for predicting post-therapy prognosis of relapsing-remitting multiple sclerosis (RRMS) patient, and method for determining applicability of novel therapy
CA2963712A1 (en) 2014-10-21 2016-04-28 Ablynx Nv Treatment of il-6r related diseases
CA2972393A1 (en) 2015-02-27 2016-09-01 Chugai Seiyaku Kabushiki Kaisha Composition for treating il-6-related diseases
WO2018203545A1 (ja) 2017-05-02 2018-11-08 国立研究開発法人国立精神・神経医療研究センター Il-6及び好中球の関連する疾患の治療効果の予測及び判定方法
WO2019151418A1 (ja) 2018-01-31 2019-08-08 元一 加藤 Il-6阻害剤を含有する喘息の治療剤
EP3957324A4 (de) 2019-04-17 2023-02-08 Hiroshima University Therapeutikum für die urologische onkologie, dadurch gekennzeichnet, dass es in kombination mit il-6 -inhibitor und ccr2 -inhibitor verabreicht wird
MX2022005654A (es) 2019-11-20 2022-06-22 Chugai Pharmaceutical Co Ltd Preparacion que contiene anticuerpo.
KR102351174B1 (ko) * 2020-05-11 2022-01-14 (주)아이테오솔루션즈 랜 포트의 혼동을 방지하는 어댑터 및 이를 포함하는 랜 포트 보안 장치
EP4263602A1 (de) 2020-12-18 2023-10-25 Ablynx N.V. Polypeptide mit variablen immunglobulin-einzeldomänen zum targeting von il-6 und tnf-alpha

Also Published As

Publication number Publication date
EP0411946A2 (de) 1991-02-06
KR0178384B1 (ko) 1999-04-01
CA2022610A1 (en) 1991-02-04
AU6003990A (en) 1991-02-07
ATE147099T1 (de) 1997-01-15
AU635296B2 (en) 1993-03-18
EP0411946A3 (en) 1992-02-12
DE69029545T2 (de) 1997-07-24
EP0411946B1 (de) 1997-01-02
JP2898064B2 (ja) 1999-05-31
US5132403A (en) 1992-07-21
JPH0429997A (ja) 1992-01-31
IL95235A0 (en) 1991-06-10
ES2096580T3 (es) 1997-03-16
DE69029545D1 (de) 1997-02-13
KR910004801A (ko) 1991-03-29
CA2022610C (en) 2001-01-30

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