IL94302A - History of N-Arleic Acid (Il-Oxo) Theoxo (Pyrido] -D-3,2 [Pyridazinate - Google Patents

History of N-Arleic Acid (Il-Oxo) Theoxo (Pyrido] -D-3,2 [Pyridazinate

Info

Publication number
IL94302A
IL94302A IL9430290A IL9430290A IL94302A IL 94302 A IL94302 A IL 94302A IL 9430290 A IL9430290 A IL 9430290A IL 9430290 A IL9430290 A IL 9430290A IL 94302 A IL94302 A IL 94302A
Authority
IL
Israel
Prior art keywords
pyrido
compound
oxo
phenyl
formula
Prior art date
Application number
IL9430290A
Other languages
English (en)
Hebrew (he)
Other versions
IL94302A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL94302A0 publication Critical patent/IL94302A0/xx
Publication of IL94302A publication Critical patent/IL94302A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
IL9430290A 1989-05-11 1990-05-06 History of N-Arleic Acid (Il-Oxo) Theoxo (Pyrido] -D-3,2 [Pyridazinate IL94302A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/350,417 US4996204A (en) 1989-05-11 1989-05-11 Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors

Publications (2)

Publication Number Publication Date
IL94302A0 IL94302A0 (en) 1991-03-10
IL94302A true IL94302A (en) 1994-01-25

Family

ID=23376622

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9430290A IL94302A (en) 1989-05-11 1990-05-06 History of N-Arleic Acid (Il-Oxo) Theoxo (Pyrido] -D-3,2 [Pyridazinate

Country Status (18)

Country Link
US (1) US4996204A (ja)
EP (1) EP0401981B1 (ja)
JP (1) JPH0631235B2 (ja)
KR (1) KR920003559B1 (ja)
AT (1) ATE121743T1 (ja)
AU (1) AU611610B2 (ja)
CA (1) CA2016326C (ja)
DE (1) DE69018876T2 (ja)
DK (1) DK0401981T3 (ja)
ES (1) ES2071016T3 (ja)
FI (1) FI93013C (ja)
HU (1) HU206714B (ja)
IE (1) IE66029B1 (ja)
IL (1) IL94302A (ja)
NO (1) NO173938C (ja)
NZ (1) NZ233599A (ja)
PT (1) PT93984B (ja)
ZA (1) ZA903564B (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954629A (en) * 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
US5716954A (en) * 1991-10-09 1998-02-10 Syntex U.S.A. Inc. Benzopyridazinone and pyridopyridazinone compounds
KR950703539A (ko) * 1992-09-28 1995-09-20 알렌 제이. 스피겔 당뇨병 합병증 치료용 치환된 피리미딘(substituted pyrimidines for control or diabetic complications)
GB9314412D0 (en) * 1993-07-13 1993-08-25 Rhone Poulenc Agriculture New compositions of matter
OA11622A (en) 1998-03-31 2004-09-16 Inst For Pharm Discovery Inc Substituted indolealkanoic acids.
TNSN99224A1 (fr) 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
EA200300433A1 (ru) * 2000-11-30 2003-10-30 Пфайзер Продактс Инк. Комбинация гамк-агонистов и ингибиторов альдегидредуктазы
EP1236720B1 (en) 2001-02-28 2005-06-15 Pfizer Products Inc. Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors
ATE348100T1 (de) 2001-03-30 2007-01-15 Pfizer Prod Inc Zwischenprodukten für die herstellung von pyridazinon aldose reductase inhibitoren.
HUP0303920A3 (en) * 2001-04-30 2004-07-28 Pfizer Prod Inc Pharmaceutical compositions containing combinations of aldose reductase inhibitor pyridazinons and cyclooxygenase 2 inhibitors
AU761191B2 (en) 2001-05-24 2003-05-29 Pfizer Products Inc. Therapies for tissue damage resulting from ischemia
US7572910B2 (en) * 2003-02-20 2009-08-11 Pfizer, Inc. Pyridazinone aldose reductase inhibitors
HUE047346T2 (hu) * 2010-07-16 2020-04-28 Univ Columbia Aldóz reduktáz inhibitorok és alkalmazásuk
US8916563B2 (en) 2010-07-16 2014-12-23 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and uses thereof
PT3757107T (pt) 2016-06-21 2023-12-14 Univ Columbia Compostos de 4-oxo-3,4-di-hidrotieno[3,4-d]piridazina como inibidores de aldose redutase e métodos de utilização dos mesmos
US11590131B2 (en) 2017-07-28 2023-02-28 Applied Therapeutics, Inc. Compositions and methods for treating galactosemia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
DE2708187A1 (de) * 1977-02-25 1978-08-31 Thomae Gmbh Dr K Neue pyrido-pyridazin-one
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4209527A (en) * 1979-05-16 1980-06-24 Pfizer Inc. Benzimidazolone derivatives
CA1160518A (en) * 1979-07-06 1984-01-17 E. I. Du Pont De Nemours And Company Coated cookware with fep topcoat
DE3684410D1 (de) * 1985-11-07 1992-04-23 Pfizer Heterocyclische oxophthalazinylessigsaeure.
US4954629A (en) * 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof

Also Published As

Publication number Publication date
DK0401981T3 (da) 1995-09-04
IL94302A0 (en) 1991-03-10
DE69018876T2 (de) 1995-08-24
DE69018876D1 (de) 1995-06-01
IE66029B1 (en) 1995-11-29
FI902335A0 (fi) 1990-05-10
JPH035481A (ja) 1991-01-11
CA2016326C (en) 1995-05-30
KR900018092A (ko) 1990-12-20
US4996204A (en) 1991-02-26
NO173938C (no) 1994-02-23
ES2071016T3 (es) 1995-06-16
EP0401981A1 (en) 1990-12-12
ATE121743T1 (de) 1995-05-15
HU206714B (en) 1992-12-28
EP0401981B1 (en) 1995-04-26
PT93984A (pt) 1991-01-08
FI93013B (fi) 1994-10-31
FI93013C (fi) 1995-02-10
HU902996D0 (en) 1990-09-28
AU5490590A (en) 1990-11-15
AU611610B2 (en) 1991-06-13
HUT54683A (en) 1991-03-28
NO902070D0 (no) 1990-05-10
IE901701L (en) 1990-11-11
ZA903564B (en) 1992-08-26
CA2016326A1 (en) 1990-11-11
NO173938B (no) 1993-11-15
NZ233599A (en) 1991-07-26
JPH0631235B2 (ja) 1994-04-27
KR920003559B1 (ko) 1992-05-04
PT93984B (pt) 1996-11-29
NO902070L (no) 1990-11-12

Similar Documents

Publication Publication Date Title
CA2016326C (en) Pyrido-pyridazinone acetic acids for treating chronic diabetic complications
US4668686A (en) Imidazoquinoline antithrombrogenic cardiotonic agents
EP0252713B1 (en) Indolinone derivatives
US5385931A (en) Sulfonamides derived from benzocyclic or benzoheterocyclic acids, their preparation and application in therapeutics
US5268386A (en) Certain 3,4-dihydro 4-oxospiro [2H-1 benzopyrans] useful for treating hyperuricemia
JPH0825877B2 (ja) 眼科治療用組成物
US4940708A (en) 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts
EP0019440B1 (en) Benzimidazolone derivatives, process for their preparation and pharmaceutical compositions containing them
CA1140928A (en) Aldose reductase inhibiting quinolylhydantions
US4574128A (en) 5-(4-Chloro-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarboxylic acids and their compositions having diuretic, saluretic and uricosuric activity
US4960785A (en) Indolinone derivatives
JPH04270273A (ja) チアゾリジン−２，４−ジオン誘導体とその塩及びその製造法
RO113856B1 (ro) Derivati ai sulfonamidei, procedee de preparare a acestora si preparate farmaceutice pentru terapia diabetului
JPH09169747A (ja) 新規置換フェニルチアゾリジン−２，４−ジオン誘導体及びその製造法
KR820001929B1 (ko) 프탈라진-4-일아세트산의 제조방법
WO1992012979A1 (en) 2,4-DIOXO-PYRIDO [2,3-d]PYRIMIDINE-3-ACETIC ACIDS AND ESTERS AND SALTS THEREOF
JPH08277266A (ja) スピロ三環式芳香族スクシンイミド誘導体、並びにヒト及び動物の糖尿病合併症治療剤
EP0112620A1 (en) 5-(Substituted phenyl) hydantoins
EP0160258A2 (en) (6,11-Dihydro-11-oxodibenz(bm,e)oxepinyl)pentanols, a process and intermediates for their preparation and their use as medicaments
NZ226030A (en) Spiro-azolone derivatives; pharmaceutical compositions

Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void