IL93940A - Diphenylalkyl 4) 5 (-Imidazoles that inhibit aromatase and medicinal preparations containing them - Google Patents

Diphenylalkyl 4) 5 (-Imidazoles that inhibit aromatase and medicinal preparations containing them

Info

Publication number
IL93940A
IL93940A IL9394090A IL9394090A IL93940A IL 93940 A IL93940 A IL 93940A IL 9394090 A IL9394090 A IL 9394090A IL 9394090 A IL9394090 A IL 9394090A IL 93940 A IL93940 A IL 93940A
Authority
IL
Israel
Prior art keywords
imidazole
pharmaceutically acceptable
acid addition
acceptable acid
addition salt
Prior art date
Application number
IL9394090A
Other languages
English (en)
Hebrew (he)
Other versions
IL93940A0 (en
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB8907218A external-priority patent/GB2229719B/en
Priority claimed from GB8907309A external-priority patent/GB2231568B/en
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Priority to IL10726090A priority Critical patent/IL107260A/en
Publication of IL93940A0 publication Critical patent/IL93940A0/xx
Priority to IL107260A priority patent/IL107260A0/xx
Publication of IL93940A publication Critical patent/IL93940A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Epoxy Resins (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Ceramic Products (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL9394090A 1989-03-30 1990-03-29 Diphenylalkyl 4) 5 (-Imidazoles that inhibit aromatase and medicinal preparations containing them IL93940A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL10726090A IL107260A (en) 1989-03-30 1990-03-29 Diphenylalkyl 4) 5 (- Imidazoles that inhibit aromatase and medicinal preparations containing them
IL107260A IL107260A0 (en) 1989-03-30 1993-10-12 Aromatase inhibiting diphenylalkyl 4(5)-imidazoles and pharmaceutical compositions containing them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8907218A GB2229719B (en) 1989-03-30 1989-03-30 Novel aromatase inhibiting 4(5)-imidazoles
GB8907309A GB2231568B (en) 1989-03-31 1989-03-31 New aromatase inhibiting 4(5)-imidazoles

Publications (2)

Publication Number Publication Date
IL93940A0 IL93940A0 (en) 1990-12-23
IL93940A true IL93940A (en) 1994-10-07

Family

ID=26295152

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9394090A IL93940A (en) 1989-03-30 1990-03-29 Diphenylalkyl 4) 5 (-Imidazoles that inhibit aromatase and medicinal preparations containing them

Country Status (19)

Country Link
EP (1) EP0390558B1 (no)
JP (1) JPH032168A (no)
CN (2) CN1046527A (no)
AT (1) ATE111084T1 (no)
AU (1) AU627559B2 (no)
CZ (1) CZ281611B6 (no)
DE (1) DE69012184T2 (no)
DK (1) DK0390558T3 (no)
ES (1) ES2063260T3 (no)
HU (2) HU205345B (no)
IE (1) IE64655B1 (no)
IL (1) IL93940A (no)
LV (1) LV11027B (no)
NO (1) NO172797C (no)
NZ (1) NZ233127A (no)
PL (1) PL162513B1 (no)
PT (1) PT93606B (no)
RU (1) RU1836354C (no)
UA (1) UA13471A (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2210875B (en) 1987-10-09 1991-05-29 Farmos Oy Aromatase inhibiting 4(5)-imidazoles
GB2229719B (en) 1989-03-30 1992-04-29 Farmos Oy Novel aromatase inhibiting 4(5)-imidazoles
GB2248058B (en) * 1990-09-21 1994-09-14 Orion Yhtymae Oy Aromatase inhibiting 4(5)-imidazoles
GB9125924D0 (en) * 1991-06-18 1992-02-05 Orion Yhtymae Oy Stereoisomers of an imidazole derivative
GB2273704B (en) * 1992-12-16 1997-01-22 Orion Yhtymae Oy Triazolyl diaryl selective aromatase inhibiting compounds
US7902247B2 (en) * 2008-01-09 2011-03-08 Allergan, Inc. Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2092569B (en) * 1981-02-05 1984-09-19 Farmos Oy Substituted imidazole derivatives and their preparation and use
GB2110663B (en) * 1981-12-04 1985-08-07 Farmos Group Ltd Imidazole derivatives
LU85747A1 (fr) * 1985-01-28 1986-08-04 Continental Pharma Derives d'imidazole leur preparation et utilisation ainsi que les compositions pharmaceutiques contenant des derives
GB2210875B (en) * 1987-10-09 1991-05-29 Farmos Oy Aromatase inhibiting 4(5)-imidazoles

Also Published As

Publication number Publication date
NO901451L (no) 1990-10-01
CZ155590A3 (en) 1996-08-14
JPH032168A (ja) 1991-01-08
HU914010D0 (en) 1992-03-30
NZ233127A (en) 1991-03-26
CN1086812A (zh) 1994-05-18
RU1836354C (ru) 1993-08-23
HUT53357A (en) 1990-10-28
PT93606B (pt) 1996-08-30
LV11027B (en) 1996-08-20
UA13471A (uk) 1997-02-28
PL162513B1 (pl) 1993-12-31
IE64655B1 (en) 1995-08-23
NO172797B (no) 1993-06-01
CZ281611B6 (cs) 1996-11-13
DE69012184T2 (de) 1995-01-05
ATE111084T1 (de) 1994-09-15
AU627559B2 (en) 1992-08-27
LV11027A (lv) 1996-02-20
NO172797C (no) 1993-09-08
AU5232590A (en) 1990-10-04
HU205345B (en) 1992-04-28
EP0390558A1 (en) 1990-10-03
CN1046527A (zh) 1990-10-31
IL93940A0 (en) 1990-12-23
IE901152L (en) 1990-09-30
PL284552A1 (en) 1991-07-29
PT93606A (pt) 1990-11-20
ES2063260T3 (es) 1995-01-01
HU206685B (en) 1992-12-28
NO901451D0 (no) 1990-03-29
DE69012184D1 (de) 1994-10-13
EP0390558B1 (en) 1994-09-07
DK0390558T3 (da) 1994-10-10
HU901894D0 (en) 1990-08-28

Similar Documents

Publication Publication Date Title
EP0311447B1 (en) Aromatase inhibiting 4(5)-imidazoles
AU682332B2 (en) Novel selective aromatase inhibiting compounds
IL102216A (en) 4) 5 (-Amidazoles and aromatase-inhibiting pharmaceutical preparations with selectivity containing them
IL93940A (en) Diphenylalkyl 4) 5 (-Imidazoles that inhibit aromatase and medicinal preparations containing them
US5439928A (en) Aromatase inhibiting 4(5)-imidazoles
GB2229719A (en) Novel aromatase inhibiting 4 (5)-imidazole
EP0476944B1 (en) Aromatase inhibiting 4(5)-imidazoles
GB2231568A (en) New aromatase inhibiting 4(5)-imidazoles
IL107260A (en) Diphenylalkyl 4) 5 (- Imidazoles that inhibit aromatase and medicinal preparations containing them

Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void