IL92240A - Serine analogues of UB-3608 antibiotic compounds, their preparation and pharmaceutical preparations containing them - Google Patents

Serine analogues of UB-3608 antibiotic compounds, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL92240A
IL92240A IL9224089A IL9224089A IL92240A IL 92240 A IL92240 A IL 92240A IL 9224089 A IL9224089 A IL 9224089A IL 9224089 A IL9224089 A IL 9224089A IL 92240 A IL92240 A IL 92240A
Authority
IL
Israel
Prior art keywords
pharmaceutically acceptable
acceptable salt
compound
serine
antibiotic
Prior art date
Application number
IL9224089A
Other languages
English (en)
Hebrew (he)
Other versions
IL92240A0 (en
Original Assignee
Bristol Myers Squibb Company N
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Company N filed Critical Bristol Myers Squibb Company N
Publication of IL92240A0 publication Critical patent/IL92240A0/xx
Priority to IL107367A priority Critical patent/IL107367A0/xx
Publication of IL92240A publication Critical patent/IL92240A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
IL9224089A 1988-11-10 1989-11-07 Serine analogues of UB-3608 antibiotic compounds, their preparation and pharmaceutical preparations containing them IL92240A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL107367A IL107367A0 (en) 1988-11-10 1993-10-22 The aglycones of serine analogs of bu-3608 antibiotics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/269,821 US4973673A (en) 1988-11-10 1988-11-10 Serine analogs of BU-3608 antibiotics

Publications (2)

Publication Number Publication Date
IL92240A0 IL92240A0 (en) 1990-07-26
IL92240A true IL92240A (en) 1994-02-27

Family

ID=23028793

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9224089A IL92240A (en) 1988-11-10 1989-11-07 Serine analogues of UB-3608 antibiotic compounds, their preparation and pharmaceutical preparations containing them

Country Status (23)

Country Link
US (1) US4973673A (no)
EP (1) EP0368349B1 (no)
JP (1) JP2817064B2 (no)
KR (1) KR930006995B1 (no)
CN (1) CN1044299A (no)
AT (1) ATE94556T1 (no)
AU (1) AU628418B2 (no)
CA (1) CA2001714C (no)
CY (1) CY1884A (no)
DE (1) DE68909170T2 (no)
DK (1) DK173464B1 (no)
EG (1) EG19153A (no)
ES (1) ES2059681T3 (no)
FI (1) FI98147C (no)
HK (1) HK151595A (no)
IE (1) IE63305B1 (no)
IL (1) IL92240A (no)
MY (1) MY110238A (no)
NO (1) NO172393C (no)
OA (1) OA09246A (no)
PL (2) PL161784B1 (no)
PT (1) PT92263B (no)
ZA (1) ZA898566B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109122A (en) * 1987-11-02 1992-04-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Antibiotics, dexylosylbenanomicin B
US5061624A (en) * 1988-11-10 1991-10-29 Bristol-Myers Company Serine analogs of BU-3608 antibiotics
US5183808A (en) * 1988-11-10 1993-02-02 Bristol-Myers Squibb Company Method for treating fungal infections with serine analogs of BU-3608 antibiotics
US5114857A (en) * 1988-11-10 1992-05-19 Bristol-Myers Company Actinomadura hibisca microorganism useful for preparing serine analogs of BU-3608 antibiotics
JP2643404B2 (ja) * 1989-01-13 1997-08-20 財団法人微生物化学研究会 新抗生物質ｎ―アセチルベナノマイシンｂならびにその製造法
FI92207C (fi) * 1989-11-14 1994-10-10 Squibb Bristol Myers Co Menetelmä terapeuttisesti käyttökelpoisten pradimisiinijohdannaisten valmistamiseksi
US5227370A (en) * 1989-11-14 1993-07-13 Bristol-Myers Squibb Company Pradimicin derivatives
CA2030166C (en) * 1989-11-22 1997-10-07 Shimpei Aburaki Pradimicin derivatives
JP3035313B2 (ja) * 1990-03-14 2000-04-24 財団法人微生物化学研究会 ベナノマイシンａ４▲′′′▼‐ｏ‐硫酸エステルの塩類およびそれらの製造法
US5217877A (en) * 1990-09-28 1993-06-08 Bristol-Myers Squibb Company Process for the preparation of α-glucosidase inhibitor, pradimicin Q
US5843908A (en) * 1990-09-28 1998-12-01 Bristol-Myers Squibb Company Pradimicins l and fl, and derivatives thereof
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives
CA2068484A1 (en) * 1991-05-29 1992-11-30 Osamu Tenmyo Pradimicin s antibiotics
US5194371A (en) * 1991-07-31 1993-03-16 Bristol-Myers Squibb Company Production of pradimicin antibiotics
JP3134010B2 (ja) * 1991-11-26 2001-02-13 財団法人微生物化学研究会 デスアラニンベナノマイシンａ誘導体およびそれらの製造法
US5837828A (en) * 1992-04-08 1998-11-17 Bristol-Myers Squibb Co. Pradimicin derivatives
US5420261A (en) * 1992-05-29 1995-05-30 Schering Corporation Glycosides of 3'-deoxyaquayamycin antibiotics
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives
US5338728A (en) * 1992-08-14 1994-08-16 Bristol-Myers Squibb Pradimicin compounds
ZA938725B (en) * 1992-11-30 1994-05-23 Bristol Myers Squibb Co C-11 Modified pradimicin derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58154582A (ja) * 1982-03-10 1983-09-14 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体およびその製造法
US4870165A (en) * 1987-02-02 1989-09-26 Bristol-Myers Company Antifungal antibiotics

Also Published As

Publication number Publication date
PL161784B1 (pl) 1993-07-30
DE68909170D1 (de) 1993-10-21
FI98147B (fi) 1997-01-15
EP0368349A3 (en) 1991-04-24
JPH02188596A (ja) 1990-07-24
DE68909170T2 (de) 1994-03-10
NO894417D0 (no) 1989-11-07
KR930006995B1 (ko) 1993-07-26
EP0368349B1 (en) 1993-09-15
AU4461589A (en) 1990-05-17
CN1044299A (zh) 1990-08-01
OA09246A (fr) 1992-06-30
EP0368349A2 (en) 1990-05-16
DK173464B1 (da) 2000-11-27
PT92263B (pt) 1995-07-06
NO172393C (no) 1993-07-14
EG19153A (en) 1994-07-30
CY1884A (en) 1996-04-05
FI98147C (fi) 1997-04-25
DK561289D0 (da) 1989-11-09
ZA898566B (en) 1990-10-31
IE63305B1 (en) 1995-04-05
CA2001714A1 (en) 1990-05-10
ES2059681T3 (es) 1994-11-16
CA2001714C (en) 1999-01-26
KR900008049A (ko) 1990-06-02
IE893617L (en) 1990-05-10
PL161779B1 (pl) 1993-07-30
DK561289A (da) 1990-05-11
HK151595A (en) 1995-09-29
US4973673A (en) 1990-11-27
MY110238A (en) 1998-03-31
PT92263A (pt) 1990-05-31
FI895281A0 (fi) 1989-11-07
AU628418B2 (en) 1992-09-17
IL92240A0 (en) 1990-07-26
NO172393B (no) 1993-04-05
NO894417L (no) 1990-05-11
JP2817064B2 (ja) 1998-10-27
ATE94556T1 (de) 1993-10-15

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US5183808A (en) Method for treating fungal infections with serine analogs of BU-3608 antibiotics
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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
RH1 Patent not in force