IL92164A - Particle-based electrochemiluminescent test method - Google Patents
Particle-based electrochemiluminescent test methodInfo
- Publication number
- IL92164A IL92164A IL9216489A IL9216489A IL92164A IL 92164 A IL92164 A IL 92164A IL 9216489 A IL9216489 A IL 9216489A IL 9216489 A IL9216489 A IL 9216489A IL 92164 A IL92164 A IL 92164A
- Authority
- IL
- Israel
- Prior art keywords
- interest
- analyte
- binding
- assay
- particles
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
- G01N21/69—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence specially adapted for fluids, e.g. molten metal
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/30—Electrochemically active labels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Control Of El Displays (AREA)
- Control Of Indicators Other Than Cathode Ray Tubes (AREA)
- Structures Of Non-Positive Displacement Pumps (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26688288A | 1988-11-03 | 1988-11-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL92164A0 IL92164A0 (en) | 1990-07-12 |
| IL92164A true IL92164A (en) | 1996-01-19 |
Family
ID=23016372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9216489A IL92164A (en) | 1988-11-03 | 1989-10-31 | Particle-based electrochemiluminescent test method |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP0757252A3 (de) |
| JP (1) | JP2992974B2 (de) |
| KR (1) | KR0143993B1 (de) |
| AT (1) | ATE180057T1 (de) |
| AU (1) | AU637775B2 (de) |
| CA (1) | CA2002101C (de) |
| DE (1) | DE68928994T2 (de) |
| IL (1) | IL92164A (de) |
| SG (1) | SG60022A1 (de) |
| WO (1) | WO1990005301A1 (de) |
| ZA (1) | ZA898290B (de) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5705402A (en) * | 1988-11-03 | 1998-01-06 | Igen International, Inc. | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
| US6274325B1 (en) | 1990-06-25 | 2001-08-14 | Boehringer Mannheim Gmbh | Method for carrying out a homogeneous-immunoassay based on agglutination |
| IL100867A (en) * | 1991-02-06 | 1995-12-08 | Igen Inc | Method and device for improved luminescence testing |
| JPH0534345A (ja) * | 1991-02-19 | 1993-02-09 | Tdk Corp | 化学発光を利用する抗原・抗体の測定方法 |
| CA2112675C (en) * | 1991-07-10 | 2007-03-20 | Richard J. Massey | Methods and apparatus for improved luminescence assays using particle concentration and chemiluminescence detection |
| DE69228817T2 (de) * | 1991-07-26 | 1999-09-23 | Dade Chemistry Systems Inc., Deerfield | Signalerkennungspruefung in der anwesenheit von einem suspendierten festen träger |
| ZA929351B (en) * | 1991-12-11 | 1993-06-04 | Igen Inc | Electrochemiluminescent label for DNA assays. |
| US5541113A (en) * | 1993-09-22 | 1996-07-30 | Beckman Instruments, Inc. | Method for detecting an analyte using an electrochemical luminescent transition metal label |
| WO1996003651A1 (de) | 1994-07-25 | 1996-02-08 | Boehringer Mannheim Gmbh | Metallchelat-markierte peptide |
| US5660991A (en) * | 1994-10-28 | 1997-08-26 | Lakowicz; Joseph R. | Long lifetime anisotropy (polarization) probes for clinical chemistry, immunoassays, affinity assays and biomedical research |
| US5744367A (en) * | 1994-11-10 | 1998-04-28 | Igen International, Inc. | Magnetic particle based electrochemiluminescent detection apparatus and method |
| WO1996021154A1 (en) * | 1995-01-06 | 1996-07-11 | Igen, Inc. | Electrogenerated chemiluminescence through enhanced particle luminescence |
| US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| EA001198B1 (ru) * | 1995-03-10 | 2000-12-25 | Мезо Скейл Текнолоджиз, Ллк | Мультиматричное мультиспецифическое электрохемилюминесцентное испытание |
| US6207369B1 (en) | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
| US6319670B1 (en) * | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| AU5920696A (en) * | 1995-05-18 | 1996-11-29 | Igen, Inc. | Method for derivitizing electrodes and assay methods using s uch derivitized electrodes |
| EP0957360B1 (de) | 1998-05-06 | 2002-07-31 | Roche Diagnostics GmbH | Entstörung durch Rheumafaktoren |
| US6420109B1 (en) | 1998-09-11 | 2002-07-16 | Genelabs Technologies, Inc. | Nucleic acid ligand interaction assays |
| US6136268A (en) * | 1999-08-17 | 2000-10-24 | Orion Diagnostica | Method for luminescence measurements |
| EP2405019A1 (de) * | 2001-09-10 | 2012-01-11 | Meso Scale Technologies LLC | Verfahren, Reagenzien, Kits und Vorrichtung zur Proteinfunktionsanalyse |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US9044199B2 (en) | 2004-07-13 | 2015-06-02 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20060270922A1 (en) | 2004-07-13 | 2006-11-30 | Brauker James H | Analyte sensor |
| US20090061466A1 (en) | 2006-03-09 | 2009-03-05 | Wolfgang Hoesel | Anti-drug antibody assay |
| ES2428876T3 (es) | 2006-09-12 | 2013-11-12 | F. Hoffmann-La Roche Ag | Ensayo de anticuerpo antifármaco |
| WO2008104344A1 (en) | 2007-02-27 | 2008-09-04 | F. Hoffmann-La Roche Ag | Method for the assessment of the inhibitory activity of antibodies against insulin-like growth factor i receptor |
| ES2532483T3 (es) | 2007-12-15 | 2015-03-27 | F. Hoffmann-La Roche Ag | Ensayo de distinción |
| US8264347B2 (en) | 2008-06-24 | 2012-09-11 | Trelleborg Sealing Solutions Us, Inc. | Seal system in situ lifetime measurement |
| US8614297B2 (en) | 2008-12-22 | 2013-12-24 | Hoffmann-La Roche Inc. | Anti-idiotype antibody against an antibody against the amyloid β peptide |
| ES2555864T3 (es) | 2010-08-19 | 2016-01-11 | F. Hoffmann-La Roche Ag | Ensayo para la medición de anticuerpos de unión a un anticuerpo monoclonal terapéutico |
| WO2012143380A1 (en) | 2011-04-20 | 2012-10-26 | F. Hoffmann-La Roche Ag | Microwaves for immunohistochemical analysis |
| AU2012274127B2 (en) | 2011-06-22 | 2017-06-22 | F. Hoffmann-La Roche Ag | Removal of target cells by circulating virus-specific cytotoxic T-cells using MHC class I comprising complexes |
| RU2633488C2 (ru) | 2011-12-19 | 2017-10-12 | Ф. Хоффманн-Ля Рош Аг | Способ определения свободного связывающего партнера мультиспецифичного связующего |
| BR112014017630A8 (pt) | 2012-02-01 | 2017-07-11 | Hoffmann La Roche | Métodos para a determinação de presença e/ou da quantidade de um antígeno |
| CN104136923B (zh) | 2012-03-08 | 2016-08-24 | 霍夫曼-拉罗奇有限公司 | 用于表征循环免疫复合物的多重层析-免疫测定方法 |
| ES2627482T3 (es) | 2012-07-13 | 2017-07-28 | F. Hoffmann-La Roche Ag | Procedimiento para la detección de una proteína de unión multiespecífica |
| MX361076B (es) | 2012-12-21 | 2018-11-27 | Hoffmann La Roche | Proteínas multifunción que comprenden complejo mayor de histocompatibilidad (cmh) de clase i multivalente unido mediante disulfuro. |
| BR112015032960B1 (pt) | 2013-07-04 | 2021-01-05 | F. Hoffmann-La Roche Ag | imunoensaio suprimido por interferência para detectar anticorpos anti-fármaco em amostras de soro |
| CN107003305B (zh) | 2014-12-08 | 2021-04-02 | 豪夫迈·罗氏有限公司 | 用于测量维生素d的方法 |
| WO2017029346A1 (en) | 2015-08-20 | 2017-02-23 | F. Hoffmann-La Roche Ag | Particle-based immunoassay using a pegylated analyte-specific binding agent |
| CN108350066B (zh) | 2015-10-29 | 2022-04-15 | 豪夫迈·罗氏有限公司 | 抗变体Fc区抗体及使用方法 |
| CN118150838A (zh) | 2015-11-30 | 2024-06-07 | 豪夫迈·罗氏有限公司 | 用于测定Fc区修饰的抗体的免疫测定法 |
| JP7065781B2 (ja) | 2016-03-07 | 2022-05-12 | エフ．ホフマン－ラ ロシュ アーゲー | 抗ｐ５３抗体の検出 |
| ES2865511T3 (es) | 2017-02-02 | 2021-10-15 | Hoffmann La Roche | Inmunoanálisis que usa al menos dos agentes de unión específica a analito pegilado |
| CA3081801C (en) | 2017-11-29 | 2022-12-20 | F. Hoffman-La Roche Ag | Target interference suppressed anti-drug antibody assay |
| WO2019201901A1 (en) | 2018-04-18 | 2019-10-24 | F. Hoffmann-La Roche Ag | Novel anti-thymidine kinase antibodies |
| JP7577647B2 (ja) | 2018-08-31 | 2024-11-05 | エフ． ホフマン－ラ ロシュ アーゲー | Ｄｌｂｃｌについての予後指標におけるチミジンキナーゼ（ｔｋ－１） |
| EP3902830A1 (de) | 2018-12-30 | 2021-11-03 | F. Hoffmann-La Roche AG | Antikörper gegen karnickel-cd19 und verfahren zur verwendung |
| JP7273195B2 (ja) | 2019-05-13 | 2023-05-12 | エフ． ホフマン－ラ ロシュ アーゲー | 干渉抑制薬物動態イムノアッセイ |
| WO2021013781A1 (en) | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | Substance p as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2021013784A1 (en) | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a8 as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2021013785A1 (en) | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a9 as blood biomarker for the non-invasive diagnosis of endometriosis |
| CN114144676A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | S100a6作为血液生物标志物用于子宫内膜异位症的非侵入性诊断 |
| BR112022001140A2 (pt) | 2019-07-22 | 2022-03-15 | Hoffmann La Roche | Métodos para avaliar se um paciente tem endometriose ou está em risco de desenvolver endometriose, selecionar um paciente para terapia e monitorar um paciente que sofre de endometriose ou que está sendo tratado para endometriose |
| JP2023502360A (ja) | 2019-11-15 | 2023-01-24 | エフ．ホフマン－ラ ロシュ アーゲー | 患者試料における質量分析測定のためのβ－ラクタム抗生物質の誘導体化 |
| TWI766512B (zh) | 2020-01-02 | 2022-06-01 | 瑞士商赫孚孟拉羅股份公司 | 用於判定腦中的治療性抗體量之方法 |
| JP2023530977A (ja) | 2020-06-16 | 2023-07-20 | エフ． ホフマン－ラ ロシュ アーゲー | 試料中の抗体の遊離抗原を決定するための方法 |
| CN116829951A (zh) | 2020-11-02 | 2023-09-29 | 豪夫迈·罗氏有限公司 | SARS-CoV-2核衣壳抗体 |
| CN112816703A (zh) * | 2020-12-30 | 2021-05-18 | 北京联众泰克科技有限公司 | 用于抗缪勒管激素检测的组合物及应用和磁微球电化学发光免疫检测试剂盒与检测方法 |
| WO2022207628A1 (en) | 2021-03-30 | 2022-10-06 | F. Hoffmann-La Roche Ag | Scf as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2022207685A1 (en) | 2021-04-01 | 2022-10-06 | F. Hoffmann-La Roche Ag | Psp94 as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2022214565A1 (en) | 2021-04-09 | 2022-10-13 | F. Hoffmann-La Roche Ag | Process for selecting cell clones expressing a heterologous polypeptide |
| US20240272177A1 (en) | 2021-05-17 | 2024-08-15 | Roche Diagnostics Operations, Inc. | sFRP4 AS BLOOD BIOMARKER FOR THE NON-INVASIVE DIAGNOSIS OF ADENOMYOSIS |
| CN117858905A (zh) | 2021-08-19 | 2024-04-09 | 豪夫迈·罗氏有限公司 | 多价抗变体fc区抗体及使用方法 |
| EP4423122A1 (de) | 2021-10-26 | 2024-09-04 | F. Hoffmann-La Roche AG | Für sars-cov-2 rbd spezifische monoklonale antikörper |
| CN118401674A (zh) | 2021-12-21 | 2024-07-26 | 豪夫迈·罗氏有限公司 | 用于确定水解活性的方法 |
| WO2023131594A1 (en) | 2022-01-05 | 2023-07-13 | F. Hoffmann-La Roche Ag | Derivatization of compounds in patient samples for therapeutic drug monitoring (tdm) |
| WO2023247752A1 (en) | 2022-06-23 | 2023-12-28 | F. Hoffmann-La Roche Ag | Method for diagnosing endometriosis and for classifying the stage of endometriosis |
| WO2024017985A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Fibroblast growth factor binding protein 1 (fgfbp1) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| WO2024017983A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Meteorin-like protein (metrnl) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| WO2024017982A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Leukotriene a4 hydrolase (lta4h) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| WO2024044622A1 (en) | 2022-08-24 | 2024-02-29 | Amgen Inc. | Anti-drug antibody assays |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4280815A (en) * | 1979-06-18 | 1981-07-28 | Technicon Instruments Corporation | Electrochemiluminescent immunoassay and apparatus therefor |
| US4652533A (en) * | 1983-04-28 | 1987-03-24 | Pandex Laboratories, Inc. | Method of solid phase immunoassay incorporating a luminescent label |
| US4687747A (en) * | 1984-07-02 | 1987-08-18 | Mallinckrodt, Inc. | Phenanthridinium ester as a labelling compound in luminometric immunoassay |
| DK365785A (da) * | 1984-09-17 | 1986-03-18 | Hoffmann La Roche | Metalcomplexer |
| ATE212030T1 (de) * | 1986-04-30 | 2002-02-15 | Igen Int Inc | Elektrolumineszente verbindungen und zwischenprodukte zur herstellung |
| SE458968B (sv) * | 1987-06-16 | 1989-05-22 | Wallac Oy | Biospecifikt analysfoerfarande foer flera analyter i vilket ingaar partikelraekning och maerkning med fluorescerande maerksubstanser |
| CA2002083C (en) * | 1988-11-03 | 2001-01-09 | Haresh P. Shah | Enhanced electrochemiluminescence |
-
1989
- 1989-10-31 IL IL9216489A patent/IL92164A/en active IP Right Grant
- 1989-10-31 WO PCT/US1989/004919 patent/WO1990005301A1/en active IP Right Grant
- 1989-10-31 JP JP2500352A patent/JP2992974B2/ja not_active Expired - Lifetime
- 1989-10-31 AU AU46357/89A patent/AU637775B2/en not_active Ceased
- 1989-10-31 EP EP96202510A patent/EP0757252A3/de not_active Ceased
- 1989-10-31 KR KR1019900701404A patent/KR0143993B1/ko not_active IP Right Cessation
- 1989-10-31 EP EP89913023A patent/EP0446245B1/de not_active Expired - Lifetime
- 1989-10-31 SG SG1996011161A patent/SG60022A1/en unknown
- 1989-10-31 DE DE68928994T patent/DE68928994T2/de not_active Expired - Lifetime
- 1989-10-31 AT AT89913023T patent/ATE180057T1/de not_active IP Right Cessation
- 1989-10-31 ZA ZA898290A patent/ZA898290B/xx unknown
- 1989-11-02 CA CA002002101A patent/CA2002101C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2002101C (en) | 2002-05-28 |
| EP0446245A4 (en) | 1991-11-13 |
| KR900702368A (ko) | 1990-12-06 |
| WO1990005301A1 (en) | 1990-05-17 |
| IL92164A0 (en) | 1990-07-12 |
| CA2002101A1 (en) | 1990-05-03 |
| JPH04502209A (ja) | 1992-04-16 |
| DE68928994T2 (de) | 1999-12-16 |
| SG60022A1 (en) | 1999-02-22 |
| KR0143993B1 (ko) | 1998-07-15 |
| ZA898290B (en) | 1991-06-26 |
| EP0446245B1 (de) | 1999-05-12 |
| AU637775B2 (en) | 1993-06-10 |
| ATE180057T1 (de) | 1999-05-15 |
| AU4635789A (en) | 1990-05-28 |
| EP0757252A2 (de) | 1997-02-05 |
| EP0757252A3 (de) | 1997-04-16 |
| EP0446245A1 (de) | 1991-09-18 |
| JP2992974B2 (ja) | 1999-12-20 |
| DE68928994D1 (de) | 1999-06-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0446245B1 (de) | Elektrochemilumineszente testverfahren | |
| US6881536B1 (en) | Particle based electrochemiluminescent assays | |
| US5705402A (en) | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets | |
| US6165729A (en) | Electrochemiluminescent reaction utilizing amine-derived reductant | |
| AU641374B2 (en) | Electrochemiluminescent reaction utilizing amine-derived reductant | |
| US5779976A (en) | Apparatus for improved luminescence assays | |
| JP3128541B2 (ja) | 複数の磁石を含む磁性微粒子に基づいたルミネッセンス・アッセイのための装置 | |
| US5746974A (en) | Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection | |
| JP3182515B2 (ja) | 改良されたルミネセンス検定のための装置 | |
| US5147806A (en) | Method and apparatus for conducting electrochemiluminescence measurements | |
| EP0594766B1 (de) | Verfahren für verbesserte lumineszenz-assays unter verwendung von teilchenkonzentration und chemilumineszenznachweis | |
| US5962218A (en) | Methods and apparatus for improved luminescence assays | |
| CA2002083C (en) | Enhanced electrochemiluminescence | |
| US5770459A (en) | Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection | |
| US6451225B1 (en) | Electrochemiluminescent reaction utilizing amine-derived reductant | |
| US7462322B2 (en) | Methods and apparatus for improved luminescence assays | |
| AU676665C (en) | Methods and apparatus for improved luminescence assays usingparticle concentration and chemiluminescence detection |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted |