IL88085A - Pyrimidinyl-piperazine propanes and anti-anxiety compositions comprising them - Google Patents
Pyrimidinyl-piperazine propanes and anti-anxiety compositions comprising themInfo
- Publication number
- IL88085A IL88085A IL88085A IL8808588A IL88085A IL 88085 A IL88085 A IL 88085A IL 88085 A IL88085 A IL 88085A IL 8808588 A IL8808588 A IL 8808588A IL 88085 A IL88085 A IL 88085A
- Authority
- IL
- Israel
- Prior art keywords
- propanes
- pyrimidinyl
- anxiety
- piperazine
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Graft Or Block Polymers (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1987/002855 WO1989003831A1 (en) | 1987-10-26 | 1987-10-26 | Anti-anxiety agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL88085A true IL88085A (en) | 1993-02-21 |
Family
ID=22202642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL88085A IL88085A (en) | 1987-10-26 | 1988-10-19 | Pyrimidinyl-piperazine propanes and anti-anxiety compositions comprising them |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4994455A (ko) |
| EP (1) | EP0314363B1 (ko) |
| JP (1) | JPH0643406B2 (ko) |
| KR (1) | KR900006722B1 (ko) |
| CN (1) | CN1022246C (ko) |
| AT (1) | ATE87919T1 (ko) |
| AU (1) | AU598161B2 (ko) |
| CA (1) | CA1314881C (ko) |
| CS (2) | CS274441B2 (ko) |
| DD (2) | DD283388A5 (ko) |
| DE (1) | DE3880077T2 (ko) |
| DK (1) | DK171788B1 (ko) |
| ES (1) | ES2054823T3 (ko) |
| FI (1) | FI94638C (ko) |
| HU (2) | HU208690B (ko) |
| IE (1) | IE63285B1 (ko) |
| IL (1) | IL88085A (ko) |
| MX (1) | MX173180B (ko) |
| MY (1) | MY103435A (ko) |
| NO (2) | NO901652L (ko) |
| NZ (1) | NZ226691A (ko) |
| PH (1) | PH25106A (ko) |
| PL (2) | PL152117B1 (ko) |
| PT (1) | PT88835B (ko) |
| RU (1) | RU2029768C1 (ko) |
| WO (1) | WO1989003831A1 (ko) |
| YU (1) | YU46592B (ko) |
| ZA (1) | ZA887925B (ko) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR242678A1 (es) * | 1986-03-05 | 1993-04-30 | Gonzalez Jorge Alberto | Mejoras en instrumentos musicales de cuerda de arco. |
| US4797488A (en) * | 1987-04-03 | 1989-01-10 | American Home Products Corporation | Psychotropic polycyclic imides |
| SE8803429D0 (sv) * | 1988-09-28 | 1988-09-28 | Pharmacia Ab | Novel pyridyl- and pyrimidyl derivatives |
| ATE112769T1 (de) * | 1988-12-28 | 1994-10-15 | Suntory Ltd | Benzoxazepinderivate. |
| US5114936A (en) * | 1990-08-23 | 1992-05-19 | Hoechst-Roussel Pharmaceuticals Incorporated | 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use |
| UA77526C2 (en) * | 2002-06-07 | 2006-12-15 | Sanofi Aventis | Substituted derivatives of 1-piperazineacylpiperidine, a method for the preparation thereof and their use in therapy |
| FR2862968B1 (fr) * | 2003-12-01 | 2006-08-04 | Sanofi Synthelabo | Derives de 4-[(arylmethyl)aminomethyl]piperidine, leur preparation et leur application en therapeutique |
| FR2862967B1 (fr) * | 2003-12-01 | 2006-08-04 | Sanofi Synthelabo | Derives de (4-phenylpiperazin-1-yl)acylpiperidine, leur preparation et leur application en therapeutique |
| WO2010027567A2 (en) * | 2008-07-23 | 2010-03-11 | Schering Corporation | Tricyclic spirocycle derivatives and methods of use thereof |
| US8617801B2 (en) * | 2009-06-03 | 2013-12-31 | Carestream Health, Inc. | Film with blue dye |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US466691A (en) * | 1892-01-05 | Egg-crate | ||
| US2672460A (en) * | 1952-06-24 | 1954-03-16 | American Cyanamid Co | Disubstituted piperazines and methods of preparing the same |
| BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
| US4666911A (en) * | 1981-07-14 | 1987-05-19 | Taiho Pharmaceutical Company Limited | Allophanoylpiperazine compound and analgesic composition containing same as active ingredient |
| DE3321969A1 (de) * | 1983-06-18 | 1984-12-20 | Troponwerke GmbH & Co KG, 5000 Köln | 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| US4605655A (en) * | 1984-03-06 | 1986-08-12 | Bristol-Myers Company | Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives |
| JPS6175A (ja) * | 1984-03-06 | 1986-01-06 | ブリストル−マイア−ズ コムパニ− | 神経弛緩剤、１‐フルオロフェニルブチル‐４‐（５‐ハロ‐２‐ピリミジニル）ピペラジン誘導体 |
| US4562255A (en) * | 1984-03-30 | 1985-12-31 | American Home Products Corporation | Substituted bi-alicyclic imides |
| US4668687A (en) * | 1984-07-23 | 1987-05-26 | Bristol-Myers Company | Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones |
| AR242678A1 (es) * | 1986-03-05 | 1993-04-30 | Gonzalez Jorge Alberto | Mejoras en instrumentos musicales de cuerda de arco. |
| US4797488A (en) * | 1987-04-03 | 1989-01-10 | American Home Products Corporation | Psychotropic polycyclic imides |
-
1987
- 1987-10-26 HU HU913849A patent/HU208690B/hu not_active IP Right Cessation
- 1987-10-26 US US07/477,835 patent/US4994455A/en not_active Expired - Lifetime
- 1987-10-26 MX MX013562A patent/MX173180B/es unknown
- 1987-10-26 HU HU876036A patent/HU206109B/hu not_active IP Right Cessation
- 1987-10-26 WO PCT/US1987/002855 patent/WO1989003831A1/en active IP Right Grant
-
1988
- 1988-10-17 DE DE8888309725T patent/DE3880077T2/de not_active Expired - Fee Related
- 1988-10-17 ES ES88309725T patent/ES2054823T3/es not_active Expired - Lifetime
- 1988-10-17 EP EP88309725A patent/EP0314363B1/en not_active Expired - Lifetime
- 1988-10-17 AT AT88309725T patent/ATE87919T1/de not_active IP Right Cessation
- 1988-10-19 IL IL88085A patent/IL88085A/xx not_active IP Right Cessation
- 1988-10-21 MY MYPI88001197A patent/MY103435A/en unknown
- 1988-10-24 CA CA000581091A patent/CA1314881C/en not_active Expired - Fee Related
- 1988-10-24 JP JP63268008A patent/JPH0643406B2/ja not_active Expired - Lifetime
- 1988-10-24 ZA ZA887925A patent/ZA887925B/xx unknown
- 1988-10-24 CN CN88107386A patent/CN1022246C/zh not_active Expired - Fee Related
- 1988-10-24 DD DD88321032A patent/DD283388A5/de not_active IP Right Cessation
- 1988-10-24 DD DD88337989A patent/DD298397A5/de not_active IP Right Cessation
- 1988-10-24 PT PT88835A patent/PT88835B/pt not_active IP Right Cessation
- 1988-10-25 YU YU198988A patent/YU46592B/sh unknown
- 1988-10-25 NZ NZ226691A patent/NZ226691A/en unknown
- 1988-10-25 DK DK591488A patent/DK171788B1/da active
- 1988-10-25 AU AU24327/88A patent/AU598161B2/en not_active Ceased
- 1988-10-25 KR KR1019880013911A patent/KR900006722B1/ko not_active IP Right Cessation
- 1988-10-25 PL PL1988275476A patent/PL152117B1/pl unknown
- 1988-10-25 PL PL1988279558A patent/PL153184B1/pl unknown
- 1988-10-25 IE IE321888A patent/IE63285B1/en not_active IP Right Cessation
- 1988-10-26 PH PH37726A patent/PH25106A/en unknown
- 1988-10-26 CS CS708088A patent/CS274441B2/cs not_active IP Right Cessation
-
1989
- 1989-03-02 CS CS135189A patent/CS274446B2/cs not_active IP Right Cessation
-
1990
- 1990-04-11 NO NO90901652A patent/NO901652L/no unknown
- 1990-04-25 FI FI902070A patent/FI94638C/fi not_active IP Right Cessation
- 1990-04-25 NO NO1990901826A patent/NO901826D0/no unknown
- 1990-04-25 RU SU904743942A patent/RU2029768C1/ru active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |