DE3880077T2 - Mittel gegen angst. - Google Patents

Mittel gegen angst.

Info

Publication number
DE3880077T2
DE3880077T2 DE8888309725T DE3880077T DE3880077T2 DE 3880077 T2 DE3880077 T2 DE 3880077T2 DE 8888309725 T DE8888309725 T DE 8888309725T DE 3880077 T DE3880077 T DE 3880077T DE 3880077 T2 DE3880077 T2 DE 3880077T2
Authority
DE
Germany
Prior art keywords
anxiety
medium
propanes
piperazinyl
pyrimidinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888309725T
Other languages
English (en)
Other versions
DE3880077D1 (de
Inventor
Welch, Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE3880077D1 publication Critical patent/DE3880077D1/de
Publication of DE3880077T2 publication Critical patent/DE3880077T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08Bridged systems
DE8888309725T 1987-10-26 1988-10-17 Mittel gegen angst. Expired - Fee Related DE3880077T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/002855 WO1989003831A1 (en) 1987-10-26 1987-10-26 Anti-anxiety agents

Publications (2)

Publication Number Publication Date
DE3880077D1 DE3880077D1 (de) 1993-05-13
DE3880077T2 true DE3880077T2 (de) 1993-07-22

Family

ID=22202642

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888309725T Expired - Fee Related DE3880077T2 (de) 1987-10-26 1988-10-17 Mittel gegen angst.

Country Status (28)

Country Link
US (1) US4994455A (de)
EP (1) EP0314363B1 (de)
JP (1) JPH0643406B2 (de)
KR (1) KR900006722B1 (de)
CN (1) CN1022246C (de)
AT (1) ATE87919T1 (de)
AU (1) AU598161B2 (de)
CA (1) CA1314881C (de)
CS (2) CS274441B2 (de)
DD (2) DD298397A5 (de)
DE (1) DE3880077T2 (de)
DK (1) DK171788B1 (de)
ES (1) ES2054823T3 (de)
FI (1) FI94638C (de)
HU (2) HU208690B (de)
IE (1) IE63285B1 (de)
IL (1) IL88085A (de)
MX (1) MX173180B (de)
MY (1) MY103435A (de)
NO (2) NO901652D0 (de)
NZ (1) NZ226691A (de)
PH (1) PH25106A (de)
PL (2) PL152117B1 (de)
PT (1) PT88835B (de)
RU (1) RU2029768C1 (de)
WO (1) WO1989003831A1 (de)
YU (1) YU46592B (de)
ZA (1) ZA887925B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR242678A1 (es) * 1986-03-05 1993-04-30 Gonzalez Jorge Alberto Mejoras en instrumentos musicales de cuerda de arco.
US4797488A (en) * 1987-04-03 1989-01-10 American Home Products Corporation Psychotropic polycyclic imides
SE8803429D0 (sv) * 1988-09-28 1988-09-28 Pharmacia Ab Novel pyridyl- and pyrimidyl derivatives
EP0376633B1 (de) * 1988-12-28 1994-10-12 Suntory Limited Benzoxazepinderivate
US5114936A (en) * 1990-08-23 1992-05-19 Hoechst-Roussel Pharmaceuticals Incorporated 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use
UA77526C2 (en) * 2002-06-07 2006-12-15 Sanofi Aventis Substituted derivatives of 1-piperazineacylpiperidine, a method for the preparation thereof and their use in therapy
FR2862968B1 (fr) * 2003-12-01 2006-08-04 Sanofi Synthelabo Derives de 4-[(arylmethyl)aminomethyl]piperidine, leur preparation et leur application en therapeutique
FR2862967B1 (fr) * 2003-12-01 2006-08-04 Sanofi Synthelabo Derives de (4-phenylpiperazin-1-yl)acylpiperidine, leur preparation et leur application en therapeutique
US20110166124A1 (en) * 2008-07-23 2011-07-07 Mccormick Kevin D Tricyclic spirocycle derivatives and methods of use
US8617801B2 (en) * 2009-06-03 2013-12-31 Carestream Health, Inc. Film with blue dye

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US466691A (en) * 1892-01-05 Egg-crate
US2672460A (en) * 1952-06-24 1954-03-16 American Cyanamid Co Disubstituted piperazines and methods of preparing the same
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US4666911A (en) * 1981-07-14 1987-05-19 Taiho Pharmaceutical Company Limited Allophanoylpiperazine compound and analgesic composition containing same as active ingredient
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
JPS6175A (ja) * 1984-03-06 1986-01-06 ブリストル−マイア−ズ コムパニ− 神経弛緩剤、1‐フルオロフェニルブチル‐4‐(5‐ハロ‐2‐ピリミジニル)ピペラジン誘導体
US4562255A (en) * 1984-03-30 1985-12-31 American Home Products Corporation Substituted bi-alicyclic imides
US4668687A (en) * 1984-07-23 1987-05-26 Bristol-Myers Company Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones
AR242678A1 (es) * 1986-03-05 1993-04-30 Gonzalez Jorge Alberto Mejoras en instrumentos musicales de cuerda de arco.
US4797488A (en) * 1987-04-03 1989-01-10 American Home Products Corporation Psychotropic polycyclic imides

Also Published As

Publication number Publication date
HU913849D0 (en) 1992-03-30
PL279558A1 (en) 1990-01-08
CS135189A2 (en) 1990-08-14
YU46592B (sh) 1993-11-16
RU2029768C1 (ru) 1995-02-27
CS708088A2 (en) 1990-08-14
HUT58724A (en) 1992-03-30
AU2432788A (en) 1989-04-27
FI94638C (fi) 1995-10-10
KR900006722B1 (ko) 1990-09-20
PL152117B1 (en) 1990-11-30
WO1989003831A1 (en) 1989-05-05
KR890006621A (ko) 1989-06-14
DK591488D0 (da) 1988-10-25
HUT59393A (en) 1992-05-28
CN1022246C (zh) 1993-09-29
MX173180B (es) 1994-02-07
EP0314363A3 (en) 1990-07-11
US4994455A (en) 1991-02-19
DD283388A5 (de) 1990-10-10
YU198988A (en) 1990-06-30
CN1042148A (zh) 1990-05-16
PH25106A (en) 1991-02-19
HU208690B (en) 1993-12-28
PL153184B1 (en) 1991-03-29
ATE87919T1 (de) 1993-04-15
PL275476A1 (en) 1989-09-18
ES2054823T3 (es) 1994-08-16
DD298397A5 (de) 1992-02-20
MY103435A (en) 1993-06-30
CA1314881C (en) 1993-03-23
IE63285B1 (en) 1995-04-05
EP0314363A2 (de) 1989-05-03
CS274446B2 (en) 1991-04-11
NO901826D0 (no) 1990-04-25
FI902070A0 (fi) 1990-04-25
JPH0643406B2 (ja) 1994-06-08
MX13562A (es) 1993-04-01
HU206109B (en) 1992-08-28
NO901652L (no) 1990-04-11
CS274441B2 (en) 1991-04-11
DK171788B1 (da) 1997-05-26
DE3880077D1 (de) 1993-05-13
EP0314363B1 (de) 1993-04-07
JPH01157979A (ja) 1989-06-21
IE883218L (en) 1989-04-26
IL88085A (en) 1993-02-21
FI94638B (fi) 1995-06-30
AU598161B2 (en) 1990-06-14
DK591488A (da) 1989-04-27
NO901652D0 (no) 1990-04-11
PT88835B (pt) 1993-01-29
ZA887925B (en) 1990-06-27
NZ226691A (en) 1990-04-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee