IL87035A0 - Novel 3,5-dihydroxycarboxylic acids and their derivatives,process for their preparation,their use as medicines and pharmaceutical products - Google Patents
Novel 3,5-dihydroxycarboxylic acids and their derivatives,process for their preparation,their use as medicines and pharmaceutical productsInfo
- Publication number
- IL87035A0 IL87035A0 IL87035A IL8703588A IL87035A0 IL 87035 A0 IL87035 A0 IL 87035A0 IL 87035 A IL87035 A IL 87035A IL 8703588 A IL8703588 A IL 8703588A IL 87035 A0 IL87035 A0 IL 87035A0
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- opt
- substd
- cpds
- formula
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000007513 acids Chemical class 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229940127557 pharmaceutical product Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 4
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 4
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000001624 naphthyl group Chemical group 0.000 abstract 2
- 229930192474 thiophene Natural products 0.000 abstract 2
- -1 2,3-dihydroxypropyl Chemical group 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
- C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
- C07C33/486—Polycyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873722807 DE3722807A1 (de) | 1987-07-10 | 1987-07-10 | Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL87035A0 true IL87035A0 (en) | 1988-12-30 |
Family
ID=6331292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL87035A IL87035A0 (en) | 1987-07-10 | 1988-07-08 | Novel 3,5-dihydroxycarboxylic acids and their derivatives,process for their preparation,their use as medicines and pharmaceutical products |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0306649B1 (da) |
| JP (1) | JPS6445337A (da) |
| KR (1) | KR890001941A (da) |
| AT (1) | ATE73123T1 (da) |
| AU (1) | AU606712B2 (da) |
| DE (2) | DE3722807A1 (da) |
| DK (1) | DK383988A (da) |
| ES (1) | ES2031959T3 (da) |
| FI (1) | FI90412C (da) |
| GR (1) | GR3004588T3 (da) |
| HU (1) | HU199768B (da) |
| IL (1) | IL87035A0 (da) |
| NO (1) | NO167795C (da) |
| NZ (1) | NZ225343A (da) |
| PH (1) | PH27496A (da) |
| PT (1) | PT87928B (da) |
| ZA (1) | ZA884920B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5151545A (en) * | 1987-10-13 | 1992-09-29 | Pfizer Inc. | 3,5-dihydroxy-6,8-nonadienoic acids and derivatives as hypocholesterolemic agents |
| DE3826814A1 (de) * | 1988-08-06 | 1990-02-08 | Hoechst Ag | Neue 6-fluor-3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
| DE3832570A1 (de) * | 1988-09-24 | 1990-03-29 | Hoechst Ag | 7-substituierte derivate der 3,5-dihydroxyhept-6-insaeure, verfahren zur ihrer herstellung, ihre verwendung als arzneimittel, sowie zwischenprodukte |
| EP0430129A3 (en) * | 1989-11-30 | 1992-02-26 | Tanabe Seiyaku Co., Ltd. | Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor |
| JP3233403B2 (ja) * | 1991-06-19 | 2001-11-26 | 塩野義製薬株式会社 | 光学活性な中間体および該製造法 |
| JP2006519874A (ja) * | 2003-03-05 | 2006-08-31 | セルジーン・コーポレーション | ジフェニルエチレン化合物およびその使用 |
| EP2072729B1 (en) * | 2007-12-21 | 2013-06-26 | IVECO S.p.A. | Hinge for vehicle door, in particular of a van |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL102791C (da) * | 1957-08-01 | |||
| BE634738A (da) * | 1962-07-11 | 1900-01-01 | ||
| US3919304A (en) * | 1968-10-25 | 1975-11-11 | Ciba Geigy Corp | {62 -Hydroxy-{62 -(cycloalkenylphenyl)alkanoic acids, esters and salts |
| BE793686A (fr) * | 1972-01-07 | 1973-07-04 | Beecham Group Ltd | Composes di-aryliques biologiquement actifs |
| DE2212948A1 (de) * | 1972-03-17 | 1973-09-20 | Basf Ag | Verfahren zur herstellung von in alpha-stellung verzweigten alpha,betaungesaettigten aldehyden |
| JPS5559140A (en) * | 1978-10-30 | 1980-05-02 | Sankyo Co Ltd | 3,5-dihydroxypentanoic alkyl ester derivative, its preparation and remedy for hyperlipemia containing the same as the effective component |
| US4341910A (en) * | 1979-01-25 | 1982-07-27 | Texas Alkyls, Inc. | Preparation of unsaturated alcohols |
| US4459422A (en) * | 1979-08-17 | 1984-07-10 | Merck & Co., Inc. | Substituted pyranone inhibitors of cholesterol synthesis |
| US4567289A (en) * | 1979-08-17 | 1986-01-28 | Merck & Co., Inc. | Substituted pyranone inhibitors of cholesterol synthesis |
| DE2934251A1 (de) * | 1979-08-24 | 1981-03-26 | Basf Ag, 67063 Ludwigshafen | Verfahren zur herstellung von ungesaettigten alkoholen. |
| DE3160641D1 (en) * | 1980-05-13 | 1983-08-25 | Ciba Geigy Ag | Process for the preparation of benzene or naphthalene alkenyl carboxylic acid derivatives |
| FI77839C (fi) * | 1982-05-27 | 1989-05-10 | Farmos Oy | Foerfarande foer framstaellning av nya terapeutiskt effektiva trifenylalkan- och alkenderivat. |
| JPS59163336A (ja) * | 1983-03-09 | 1984-09-14 | Nippon Petrochem Co Ltd | アルデヒドの製造法 |
| HUT39142A (en) * | 1984-07-24 | 1986-08-28 | Sandoz Ag | Process for producing naphtyl-analogues of mevalolactone and derivatives and pharmaceutical compositions containing them |
| DE3523181A1 (de) * | 1985-06-28 | 1987-01-08 | Basf Ag | Verfahren zur herstellung von 2-methyl-2-alkenalen |
| US4611081A (en) * | 1985-07-05 | 1986-09-09 | Merck & Co., Inc. | Process for the preparation of HMG-CoA reductase inhibitors intermediates |
| US4745229A (en) * | 1986-02-28 | 1988-05-17 | Kuraray Company Ltd. | Process for preparing α, β-unsaturated aldehydes |
-
1987
- 1987-07-10 DE DE19873722807 patent/DE3722807A1/de not_active Withdrawn
-
1988
- 1988-07-07 DE DE8888110833T patent/DE3868794D1/de not_active Expired - Fee Related
- 1988-07-07 EP EP88110833A patent/EP0306649B1/de not_active Expired - Lifetime
- 1988-07-07 FI FI883248A patent/FI90412C/fi not_active IP Right Cessation
- 1988-07-07 AT AT88110833T patent/ATE73123T1/de not_active IP Right Cessation
- 1988-07-07 PT PT87928A patent/PT87928B/pt not_active IP Right Cessation
- 1988-07-07 ES ES198888110833T patent/ES2031959T3/es not_active Expired - Lifetime
- 1988-07-08 NO NO883071A patent/NO167795C/no unknown
- 1988-07-08 AU AU18881/88A patent/AU606712B2/en not_active Ceased
- 1988-07-08 DK DK383988A patent/DK383988A/da not_active Application Discontinuation
- 1988-07-08 JP JP63169158A patent/JPS6445337A/ja active Pending
- 1988-07-08 NZ NZ225343A patent/NZ225343A/xx unknown
- 1988-07-08 PH PH37204A patent/PH27496A/en unknown
- 1988-07-08 ZA ZA884920A patent/ZA884920B/xx unknown
- 1988-07-08 IL IL87035A patent/IL87035A0/xx unknown
- 1988-07-09 HU HU883596A patent/HU199768B/hu not_active IP Right Cessation
- 1988-07-09 KR KR1019880008547A patent/KR890001941A/ko not_active Ceased
-
1992
- 1992-05-13 GR GR920400794T patent/GR3004588T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI90412C (fi) | 1994-02-10 |
| HU199768B (en) | 1990-03-28 |
| DK383988D0 (da) | 1988-07-08 |
| GR3004588T3 (da) | 1993-04-28 |
| ES2031959T3 (es) | 1993-01-01 |
| EP0306649B1 (de) | 1992-03-04 |
| NO167795C (no) | 1991-12-11 |
| PT87928B (pt) | 1995-05-04 |
| FI90412B (fi) | 1993-10-29 |
| AU606712B2 (en) | 1991-02-14 |
| HUT47237A (en) | 1989-02-28 |
| EP0306649A1 (de) | 1989-03-15 |
| DK383988A (da) | 1989-01-11 |
| AU1888188A (en) | 1989-01-12 |
| DE3868794D1 (de) | 1992-04-09 |
| NO883071D0 (no) | 1988-07-08 |
| ATE73123T1 (de) | 1992-03-15 |
| KR890001941A (ko) | 1989-04-06 |
| PH27496A (en) | 1993-07-23 |
| FI883248A0 (fi) | 1988-07-07 |
| NO883071L (no) | 1989-01-11 |
| NO167795B (no) | 1991-09-02 |
| JPS6445337A (en) | 1989-02-17 |
| NZ225343A (en) | 1991-02-26 |
| ZA884920B (en) | 1989-01-17 |
| PT87928A (pt) | 1989-06-30 |
| DE3722807A1 (de) | 1989-01-19 |
| FI883248A7 (fi) | 1989-01-11 |
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