GB938436A - Pyrazole derivatives and a process for the preparation thereof - Google Patents
Pyrazole derivatives and a process for the preparation thereofInfo
- Publication number
- GB938436A GB938436A GB3223060A GB3223060A GB938436A GB 938436 A GB938436 A GB 938436A GB 3223060 A GB3223060 A GB 3223060A GB 3223060 A GB3223060 A GB 3223060A GB 938436 A GB938436 A GB 938436A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- compound
- preparation
- condensing
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The invention comprises compounds of general formula <FORM:0938436/IV(a)/1> wherein R1 and R2 are alkyl (1-4C) and R3 is a 2-thienyl or 3-pyridyl radical; and their acid addition salts; and their preparation by condensing a compound of general formula <FORM:0938436/IV(a)/2> (as sodium salt is an example) with a compound of general formula <FORM:0938436/IV(a)/3> Nitriles of the second general formula above may be prepared from a substituted acetonitrile by reaction with an appropriate carboxylic acid ester. Hydrazines of the third general formula above may be prepared by condensing an N-alkyl-4-piperidone with a monoacylhydrazine followed by catalytic reduction and acid hydrolysis. Pharmaceutical compositions contain, in addition to an inert carrier, a compound of the invention. Oral (tablets) and parenteral (solutions) administration are mentioned. The compounds have antiphlogistic, analgetic, antipyretic, adrenolytic, antirheumatic or serotonin inhibiting effect.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH7940059A CH372680A (en) | 1959-10-14 | 1959-10-14 | Process for the preparation of new pyrazole derivatives |
| CH791860 | 1960-07-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB938436A true GB938436A (en) | 1963-10-02 |
Family
ID=25702454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3223060A Expired GB938436A (en) | 1959-10-14 | 1960-09-20 | Pyrazole derivatives and a process for the preparation thereof |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB938436A (en) |
-
1960
- 1960-09-20 GB GB3223060A patent/GB938436A/en not_active Expired
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