IL86007A0 - 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them - Google Patents

6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL86007A0
IL86007A0 IL86007A IL8600788A IL86007A0 IL 86007 A0 IL86007 A0 IL 86007A0 IL 86007 A IL86007 A IL 86007A IL 8600788 A IL8600788 A IL 8600788A IL 86007 A0 IL86007 A0 IL 86007A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
substituted purine
purine nucleosides
Prior art date
Application number
IL86007A
Other languages
English (en)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878708512A external-priority patent/GB8708512D0/en
Priority claimed from GB878712691A external-priority patent/GB8712691D0/en
Priority claimed from GB878723013A external-priority patent/GB8723013D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL86007A0 publication Critical patent/IL86007A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL86007A 1987-04-09 1988-04-07 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them IL86007A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB878708512A GB8708512D0 (en) 1987-04-09 1987-04-09 Therapeutic nucleosides
GB878712691A GB8712691D0 (en) 1987-05-29 1987-05-29 Therapeutic nucleosides
GB878723013A GB8723013D0 (en) 1987-09-30 1987-09-30 Therapeutic nucleosides

Publications (1)

Publication Number Publication Date
IL86007A0 true IL86007A0 (en) 1988-09-30

Family

ID=27263377

Family Applications (1)

Application Number Title Priority Date Filing Date
IL86007A IL86007A0 (en) 1987-04-09 1988-04-07 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US5068320A (cs)
EP (1) EP0286425B1 (cs)
JP (1) JP2763888B2 (cs)
KR (1) KR880012630A (cs)
AP (1) AP78A (cs)
AT (1) ATE116984T1 (cs)
AU (1) AU608590B2 (cs)
CA (1) CA1326237C (cs)
CS (1) CS274461B2 (cs)
DE (1) DE3852710T2 (cs)
DK (1) DK191688A (cs)
FI (1) FI87214C (cs)
HU (1) HU201954B (cs)
IL (1) IL86007A0 (cs)
MC (1) MC1915A1 (cs)
NO (1) NO171641C (cs)
NZ (1) NZ224189A (cs)
PL (1) PL154956B1 (cs)
PT (1) PT87191B (cs)
RU (1) RU1779256C (cs)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185437A (en) * 1987-04-09 1993-02-09 Burroughs Wellcome Co. Therapeutic nucleosides
IL86007A0 (en) * 1987-04-09 1988-09-30 Wellcome Found 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
US5077280A (en) * 1988-04-12 1991-12-31 Brown University Research Foundation Treatment of viral infections
IE882585L (en) * 1988-08-25 1990-02-25 Prendergast Patrick T Viral treatment system
EP0366385B1 (en) * 1988-10-24 1993-06-09 The Wellcome Foundation Limited Guanine derivatives having antiviral activity and their pharmaceutically acceptable salts
WO1990006312A1 (de) * 1988-11-29 1990-06-14 Institut Für Molekularbiologie Und Analytik (Ima) Gmbh 2', 3'-didesoxyribofuranoside und ein verfahren zu ihrer herstellung
JP2619710B2 (ja) * 1989-02-27 1997-06-11 日本製紙 株式会社 ２′，３′−ジデオキシプリンヌクレオシド類の製造方法
US5585364A (en) * 1989-04-13 1996-12-17 British Technology Group Limited Antiviral compounds
US5013829A (en) * 1989-04-26 1991-05-07 University Of Iowa Research Foundation Stable congener of 2',3'-dideoxyadenosine
DE4020529A1 (de) * 1989-09-12 1991-03-21 Roxana Vasiloiu Multifunktionelle(s) enzym(e) mit nucleosid-didesoxyribosyltransferase(n) und/oder nucleoside-desoxyribosyltransferasen(n) und/oder kinease- und/oder reduktase- und/oder desaminase- und/oder polymerase-aktivitaet
JPH0637391B2 (ja) * 1989-09-29 1994-05-18 日本製紙株式会社 抗エイズウイルス剤
PT95516A (pt) * 1989-10-06 1991-08-14 Wellcome Found Processo para a preparacao de derivados de 2',3'-didesoxi nucleosidos 6-substituidos
EP0544668A1 (en) * 1990-02-09 1993-06-09 THE UNITED STATES OF AMERICA as represented by the Secretary UNITED STATES DEPARTMENT OF COMMERCE -6-fluoro-9-(2,3-dideoxy-b-d-glycero-pentofuranosyl)-9h-purines and their use asantiviral agents
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
CN1117751C (zh) * 1998-12-23 2003-08-13 希拉生物化学股份有限公司 抗病毒的核苷类似物
CN101220071B (zh) * 2008-01-17 2011-04-06 南京长澳医药科技有限公司 稳定的6-甲氧基-2’,3’-双脱氧鸟嘌呤核苷及其制备方法和包含它的药物组合物
CN102234280B (zh) * 2010-04-26 2014-01-08 北京大学 D,l-鸟嘌呤核苷类似物及其制备方法和应用
MX2013003153A (es) 2010-09-22 2013-05-01 Alios Biopharma Inc Analogos de nucleotidos sustituidos.
ES2583877T3 (es) * 2011-06-01 2016-09-22 Janus Biotherapeutics, Inc. Moduladores novedosos del sistema inmunitario
EP2794630A4 (en) 2011-12-22 2015-04-01 Alios Biopharma Inc SUBSTITUTED PHOSPHORTHIOAT NUCLEOTIDE ANALOGUE
HK1206362A1 (zh) 2012-03-21 2016-01-08 Alios Biopharma, Inc. 硫代氨基磷酸酯核苷酸前藥的固體形式
US9012427B2 (en) 2012-03-22 2015-04-21 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
EP2964647A1 (en) * 2013-03-05 2016-01-13 F. Hoffmann-La Roche AG Inhibitors of bruton's tyrosine kinase

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1573777A (en) * 1977-11-03 1980-08-28 Wellcome Found 9-d-arabinonucleosides and an enzymatic process for their preparation
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
NZ215486A (en) * 1985-03-16 1988-09-29 Wellcome Found 3'-azido-3'-deoxythymidine antiretroviral compositions (zidovudine, azt)
ES8801303A1 (es) * 1985-05-15 1987-12-16 Wellcome Found Un procedimiento para preparar una formulacion farmaceutica que contiene un 2'3'-didesoxi-nucleosido.
JPS62501777A (ja) * 1985-08-26 1987-07-16 アメリカ合衆国 ２′，３′―ジデオキシシチジンを含有する抗ｈｔｌｖ―３／ｌａｖ剤
EP0217580A3 (en) * 1985-09-17 1990-11-07 The Wellcome Foundation Limited Therapeutic nucleosides
IT1203558B (it) * 1986-05-20 1989-02-15 Firestone Int Dev Spa Metodo per la realizzazione di un pneumatico radiale di prima fase per veicoli
EP0342203B1 (en) * 1987-03-24 1994-07-06 Nycomed Imaging As 2',3' dideoxyribofuranoxide derivatives
IL86007A0 (en) * 1987-04-09 1988-09-30 Wellcome Found 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
IL87149A (en) * 1987-07-20 1994-05-30 Merck & Co Inc 6-Piperazinyl derivatives of purine and its 3- and 9-deaza isosteres, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPS63267796A (ja) 1988-11-04
DK191688A (da) 1988-10-10
AU1444488A (en) 1988-10-13
CA1326237C (en) 1994-01-18
NO881537L (no) 1988-10-10
DE3852710D1 (de) 1995-02-23
HU201954B (en) 1991-01-28
CS242188A2 (en) 1990-09-12
DK191688D0 (da) 1988-04-08
EP0286425A3 (en) 1990-12-05
NO171641C (no) 1993-04-14
ATE116984T1 (de) 1995-01-15
MC1915A1 (fr) 1989-04-06
EP0286425B1 (en) 1995-01-11
JP2763888B2 (ja) 1998-06-11
DE3852710T2 (de) 1995-05-24
EP0286425A2 (en) 1988-10-12
KR880012630A (ko) 1988-11-28
FI87214C (fi) 1992-12-10
US5068320A (en) 1991-11-26
PL154956B1 (en) 1991-10-31
PT87191B (pt) 1993-02-26
NO881537D0 (no) 1988-04-08
PT87191A (pt) 1988-05-01
NO171641B (no) 1993-01-04
AP78A (en) 1990-03-12
HUT48269A (en) 1989-05-29
AP8800086A0 (en) 1988-02-01
FI881651A0 (fi) 1988-04-08
FI881651L (fi) 1988-10-10
CS274461B2 (en) 1991-04-11
RU1779256C (ru) 1992-11-30
AU608590B2 (en) 1991-04-11
PL271722A1 (en) 1989-01-23
NZ224189A (en) 1991-09-25
FI87214B (fi) 1992-08-31

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