IL77951A - Method of somatotropin solubilization and naturation - Google Patents
Method of somatotropin solubilization and naturationInfo
- Publication number
- IL77951A IL77951A IL77951A IL7795186A IL77951A IL 77951 A IL77951 A IL 77951A IL 77951 A IL77951 A IL 77951A IL 7795186 A IL7795186 A IL 7795186A IL 77951 A IL77951 A IL 77951A
- Authority
- IL
- Israel
- Prior art keywords
- naturation
- somatotropin
- solution
- protein
- solubilization
- Prior art date
Links
- 102000018997 Growth Hormone Human genes 0.000 title abstract 4
- 108010051696 Growth Hormone Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 230000007928 solubilization Effects 0.000 title abstract 2
- 238000005063 solubilization Methods 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- HHVIBTZHLRERCL-UHFFFAOYSA-N sulfonyldimethane Chemical compound CS(C)(=O)=O HHVIBTZHLRERCL-UHFFFAOYSA-N 0.000 abstract 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
- 239000004202 carbamide Substances 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Beans For Foods Or Fodder (AREA)
- Cosmetics (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70434185A | 1985-02-22 | 1985-02-22 | |
US06/704,677 US4652630A (en) | 1985-02-22 | 1985-02-22 | Method of somatotropin naturation |
Publications (1)
Publication Number | Publication Date |
---|---|
IL77951A true IL77951A (en) | 1990-11-05 |
Family
ID=27107301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL77951A IL77951A (en) | 1985-02-22 | 1986-02-21 | Method of somatotropin solubilization and naturation |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0192629B2 (fr) |
JP (1) | JP2572963B2 (fr) |
KR (1) | KR890003082B1 (fr) |
CN (1) | CN1010097B (fr) |
AT (1) | ATE66930T1 (fr) |
AU (3) | AU587423B2 (fr) |
CA (1) | CA1268300C (fr) |
DE (1) | DE3681185D1 (fr) |
DK (1) | DK172526B1 (fr) |
ES (1) | ES8800957A1 (fr) |
IE (1) | IE58871B1 (fr) |
IL (1) | IL77951A (fr) |
NZ (1) | NZ215259A (fr) |
SU (1) | SU1542402A3 (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU612133B2 (en) * | 1987-02-20 | 1991-07-04 | Natinco Nv | Production of proteins in active forms |
US4985544A (en) * | 1987-08-04 | 1991-01-15 | Kyowa Hakko Kogyo Co., Ltd. | Process for renaturing fish growth hormone |
JP2669859B2 (ja) * | 1987-08-04 | 1997-10-29 | 協和醗酵工業株式会社 | タンパク質の再活性化法 |
JPH01132598A (ja) * | 1987-10-14 | 1989-05-25 | Pitman Moore Inc | 変性剤溶液中に含まれる組換え蛋白質における分子内ジスルフィド結合の生成を促進する方法 |
JPH01257491A (ja) * | 1988-04-08 | 1989-10-13 | Tosoh Corp | 不溶性融合異種蛋白質の処理方法 |
US5089473A (en) | 1988-08-29 | 1992-02-18 | Monsanto Company | Somatotropin variants and their use |
DE3835350A1 (de) * | 1988-10-17 | 1990-04-19 | Boehringer Mannheim Gmbh | Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern |
US5064943A (en) * | 1988-12-16 | 1991-11-12 | American Cyanamid Company | Method for solubilization and naturation of somatotropin |
JP2517100B2 (ja) * | 1989-03-08 | 1996-07-24 | 協和醗酵工業株式会社 | ヒト顆粒球コロニ―刺激因子活性を有する蛋白質の精製法 |
US5182369A (en) * | 1990-02-28 | 1993-01-26 | Monsanto Company | Method for purifying somatotropin monomers |
US5023323A (en) * | 1990-09-12 | 1991-06-11 | Monsanto Company | Method of somatotropin naturation |
AU2592395A (en) * | 1994-05-19 | 1995-12-18 | Monsanto Company | Method for purifying somatotropin monomers |
CA2194177A1 (fr) * | 1994-07-25 | 1996-02-08 | Jui Yoa Chang | Procede de repliement de proteines telles que l'hirudine ou le facteur de croissance epidermique de recombinaison |
ZA9711733B (en) * | 1996-12-31 | 1998-07-01 | Monsanto Co | Method for solubilization and naturation of somatotropins |
JP2002504932A (ja) * | 1997-06-27 | 2002-02-12 | モンサント・カンパニー | ソマトトロピンによる動物の蹄の成長促進 |
BRPI0613653A2 (pt) * | 2005-07-25 | 2011-01-25 | Trubion Pharmaceuticals Inc | composições e métodos para desagregação de proteìna |
WO2007060768A1 (fr) | 2005-11-24 | 2007-05-31 | Murata Manufacturing Co., Ltd. | Transducteur electroacoustique |
NZ568809A (en) | 2005-12-22 | 2011-08-26 | Genentech Inc | Recovering and purification of VEGF proteins from prokaryotic cells using polyanionic agents |
AR062069A1 (es) * | 2006-07-14 | 2008-10-15 | Genentech Inc | Replegado de proteinas recombinantes |
US11959125B2 (en) | 2016-09-15 | 2024-04-16 | Sun Genomics, Inc. | Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample |
CA3036702A1 (fr) * | 2016-09-15 | 2018-03-22 | Sun Genomics Inc. | Procede universel d'extraction de molecules d'acides nucleiques a partir d'une population diverse d'un ou plusieurs types de microbes dans un echantillon |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ204477A (en) * | 1982-06-07 | 1986-09-10 | Celltech Ltd | Recombinant dna method for production of chymosin:initial solubilisation of insoluble precursor |
GR79124B (fr) * | 1982-12-22 | 1984-10-02 | Genentech Inc | |
ATE107356T1 (de) * | 1983-03-25 | 1994-07-15 | Celltech Ltd | Verfahren zur herstellung eines proteins. |
-
1986
- 1986-02-20 ES ES552233A patent/ES8800957A1/es not_active Expired
- 1986-02-21 DE DE8686870023T patent/DE3681185D1/de not_active Expired - Fee Related
- 1986-02-21 DK DK198600809A patent/DK172526B1/da not_active IP Right Cessation
- 1986-02-21 AT AT86870023T patent/ATE66930T1/de not_active IP Right Cessation
- 1986-02-21 KR KR1019860001222A patent/KR890003082B1/ko not_active IP Right Cessation
- 1986-02-21 EP EP86870023A patent/EP0192629B2/fr not_active Expired - Lifetime
- 1986-02-21 IL IL77951A patent/IL77951A/xx not_active IP Right Cessation
- 1986-02-21 JP JP61037159A patent/JP2572963B2/ja not_active Expired - Lifetime
- 1986-02-21 AU AU53853/86A patent/AU587423B2/en not_active Ceased
- 1986-02-21 CN CN86100915A patent/CN1010097B/zh not_active Expired
- 1986-02-21 SU SU4022043A patent/SU1542402A3/ru active
- 1986-02-21 NZ NZ215259A patent/NZ215259A/xx unknown
- 1986-02-21 CA CA502494A patent/CA1268300C/fr not_active Expired
- 1986-02-24 IE IE46686A patent/IE58871B1/en not_active IP Right Cessation
-
1989
- 1989-05-19 AU AU34980/89A patent/AU621111B2/en not_active Ceased
- 1989-08-03 AU AU39258/89A patent/AU618386B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
ES552233A0 (es) | 1987-12-01 |
DK172526B1 (da) | 1998-11-16 |
AU587423B2 (en) | 1989-08-17 |
AU3925889A (en) | 1990-04-05 |
IE58871B1 (en) | 1993-11-17 |
CA1268300A (fr) | 1990-04-24 |
KR890003082B1 (ko) | 1989-08-21 |
NZ215259A (en) | 1989-11-28 |
AU621111B2 (en) | 1992-03-05 |
CA1268300C (fr) | 1990-04-24 |
AU618386B2 (en) | 1991-12-19 |
CN86100915A (zh) | 1986-08-20 |
DE3681185D1 (de) | 1991-10-10 |
DK80986A (da) | 1986-08-23 |
IE860466L (en) | 1986-08-22 |
EP0192629A2 (fr) | 1986-08-27 |
KR860006541A (ko) | 1986-09-13 |
CN1010097B (zh) | 1990-10-24 |
EP0192629B1 (fr) | 1991-09-04 |
EP0192629A3 (en) | 1988-07-27 |
DK80986D0 (da) | 1986-02-21 |
AU3498089A (en) | 1989-09-14 |
AU5385386A (en) | 1986-08-28 |
ES8800957A1 (es) | 1987-12-01 |
JPS61195698A (ja) | 1986-08-29 |
ATE66930T1 (de) | 1991-09-15 |
EP0192629B2 (fr) | 1997-03-05 |
JP2572963B2 (ja) | 1997-01-16 |
SU1542402A3 (ru) | 1990-02-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU587423B2 (en) | Method of somatotropin solubilization and naturation | |
US4530787B1 (fr) | ||
DE3270880D1 (en) | Process for removal of nitrogen oxides and sulfur oxides from waste gases | |
FI860566A0 (fi) | Foerfarande foer framstaellning av skummande blandningar. | |
AU583723B2 (en) | Process for renaturing of proteins | |
AU4675089A (en) | Method for solubilization and naturation of somatotropin | |
ATE76435T1 (de) | Solubilisation und oxidation von somatotropin aus transformierten mikroorganismen. | |
FI905985A (fi) | Menetelmä somatotropiinien saamiseksi liukoisiksi ja naturoimiseksi käyttämällä alhaista urean konsentraatiota | |
DE3680255D1 (de) | D-aminsaeureoxidase und verfahren zu deren isolierung. | |
HUT40140A (en) | Process for solubilizing and restoring homatropin | |
ES2001642A6 (es) | Procedimiento de obtencion de 1,1 - dioxido del acido 6 - amino penicilanico por oxidacion del acido 6 - amino penicilanico | |
SU1172283A1 (ru) | Способ переработки молибденсодержащих продуктов | |
SU1297464A1 (ru) | Способ вскрытия молибденсодержащих руд | |
ES2005030A6 (es) | Procedimiento para recuperarcion de plata a partir de una torta de plomonplata. | |
SU1520867A1 (ru) | Способ переработки вольфрамитовых концентратов |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
HP | Change in proprietorship | ||
KB | Patent renewed | ||
EXP | Patent expired |