IL76175A - N-substituted tricyclic oxindole carboxamides and pharmaceutical compositions containing them - Google Patents

N-substituted tricyclic oxindole carboxamides and pharmaceutical compositions containing them

Info

Publication number
IL76175A
IL76175A IL76175A IL7617585A IL76175A IL 76175 A IL76175 A IL 76175A IL 76175 A IL76175 A IL 76175A IL 7617585 A IL7617585 A IL 7617585A IL 76175 A IL76175 A IL 76175A
Authority
IL
Israel
Prior art keywords
sub
pharmaceutical compositions
compositions containing
substituted tricyclic
tricyclic oxindole
Prior art date
Application number
IL76175A
Other languages
English (en)
Other versions
IL76175A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to IL87402A priority Critical patent/IL87402A/xx
Priority to IL8740385A priority patent/IL87403A/xx
Priority to IL8740485A priority patent/IL87404A/xx
Publication of IL76175A0 publication Critical patent/IL76175A0/xx
Priority to IL87403A priority patent/IL87403A0/xx
Priority to IL87404A priority patent/IL87404A0/xx
Priority to IL87402A priority patent/IL87402A0/xx
Publication of IL76175A publication Critical patent/IL76175A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Filling Or Discharging Of Gas Storage Vessels (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Medicinal Preparation (AREA)
IL76175A 1984-08-24 1985-08-23 N-substituted tricyclic oxindole carboxamides and pharmaceutical compositions containing them IL76175A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IL87402A IL87402A (en) 1984-08-24 1985-08-23 Oxo-n-(hetero)aryl-2h-furo-(and pyrano)-(2,3-f)-indolecarboxamides and pharmaceutical compositions containing them
IL8740385A IL87403A (en) 1984-08-24 1985-08-23 5,n-disubstituted-6-oxo-dihydro-6h-furo-(and thieno)-(3,2-f)indole-7-carboxamides and pharmaceutical compositions containing them
IL8740485A IL87404A (en) 1984-08-24 1985-08-23 N-substituted tricyclic oxindole carboxamides and pharmaceutical compositions containing them
IL87403A IL87403A0 (en) 1984-08-24 1988-08-10 Tricyclic oxindole derivatives and pharmaceutical compositions containing them
IL87404A IL87404A0 (en) 1984-08-24 1988-08-10 Tricyclic oxindole derivatives and pharmaceutical compositions containing them
IL87402A IL87402A0 (en) 1984-08-24 1988-08-10 Tricyclic oxindole derivatives and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1984/001371 WO1986001510A1 (en) 1984-08-24 1984-08-24 Tricyclic oxindole antiinflammatory agents

Publications (2)

Publication Number Publication Date
IL76175A0 IL76175A0 (en) 1985-12-31
IL76175A true IL76175A (en) 1989-08-15

Family

ID=22182243

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76175A IL76175A (en) 1984-08-24 1985-08-23 N-substituted tricyclic oxindole carboxamides and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4695571A (pl)
EP (1) EP0173520B1 (pl)
JP (1) JPS6157554A (pl)
KR (1) KR870001144B1 (pl)
AT (1) ATE49211T1 (pl)
AU (1) AU553859B2 (pl)
CA (1) CA1244427A (pl)
DE (1) DE3575140D1 (pl)
DK (1) DK160098C (pl)
EG (1) EG17287A (pl)
ES (2) ES8704497A1 (pl)
FI (1) FI79319C (pl)
GR (1) GR852026B (pl)
HU (2) HU203238B (pl)
IE (1) IE58739B1 (pl)
IL (1) IL76175A (pl)
PH (1) PH23065A (pl)
PL (2) PL147393B1 (pl)
PT (1) PT81004B (pl)
WO (1) WO1986001510A1 (pl)
ZA (1) ZA856403B (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPS63223492A (ja) * 1987-03-11 1988-09-16 Okawara Mfg Co Ltd 熱交換器
WO1990008146A1 (en) * 1989-01-10 1990-07-26 Pfizer Inc. Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides
HU215112B (hu) * 1989-01-10 1998-12-28 Pfizer Inc. Eljárás gyulladáscsökkentő 1-heteroaril-3-acil-2-oxindol-származékok előállítására
US5300655A (en) * 1989-04-18 1994-04-05 Pfizer Inc. 2-carboxy-thiophene derivatives
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
JPH04217684A (ja) * 1990-05-30 1992-08-07 Shionogi & Co Ltd アルド−ス還元酵素阻害物質
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
WO2005041957A1 (en) * 2003-10-29 2005-05-12 Pfizer Products Inc. Oxindole derivatives and their use as phosphodiesterase type 2 inhibitors
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE756447A (fr) * 1969-10-15 1971-03-22 Pfizer Oxindolecarboxamides
US3749731A (en) * 1971-07-08 1973-07-31 Warner Lambert Co 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide
US4644005A (en) * 1984-10-31 1987-02-17 Pfizer Inc. Oxindole antiinflammatory agents

Also Published As

Publication number Publication date
IL76175A0 (en) 1985-12-31
DK160098B (da) 1991-01-28
DK160098C (da) 1991-06-24
FI79319C (fi) 1989-12-11
AU4663785A (en) 1986-02-27
JPS6157554A (ja) 1986-03-24
ES546377A0 (es) 1987-04-01
US4695571A (en) 1987-09-22
IE58739B1 (en) 1993-11-03
ES552044A0 (es) 1987-06-01
KR870002143A (ko) 1987-03-30
EG17287A (en) 1993-02-28
HU203350B (en) 1991-07-29
ATE49211T1 (de) 1990-01-15
HU902020D0 (en) 1990-07-28
KR870001144B1 (ko) 1987-06-11
DK382685A (da) 1986-02-25
WO1986001510A1 (en) 1986-03-13
FI861704A0 (fi) 1986-04-23
JPH0450316B2 (pl) 1992-08-13
ZA856403B (en) 1987-04-29
EP0173520A2 (en) 1986-03-05
DK382685D0 (da) 1985-08-23
PL255089A1 (en) 1986-12-30
AU553859B2 (en) 1986-07-31
FI79319B (fi) 1989-08-31
CA1244427A (en) 1988-11-08
PL147395B1 (en) 1989-05-31
PT81004A (en) 1985-09-01
FI861704A (fi) 1986-04-23
DE3575140D1 (de) 1990-02-08
ES8706116A1 (es) 1987-06-01
EP0173520A3 (en) 1986-05-14
IE852081L (en) 1986-02-24
EP0173520B1 (en) 1990-01-03
HUT47580A (en) 1989-03-28
PL147393B1 (en) 1989-05-31
ES8704497A1 (es) 1987-04-01
HU203238B (en) 1991-06-28
PT81004B (pt) 1987-12-30
PH23065A (en) 1989-03-27
GR852026B (pl) 1985-12-19

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Legal Events

Date Code Title Description
RH Patent void