IL73318A - Pharmaceutical compositions in lipid emulsion form for intravenous injection and their preparation - Google Patents

Pharmaceutical compositions in lipid emulsion form for intravenous injection and their preparation

Info

Publication number
IL73318A
IL73318A IL73318A IL7331884A IL73318A IL 73318 A IL73318 A IL 73318A IL 73318 A IL73318 A IL 73318A IL 7331884 A IL7331884 A IL 7331884A IL 73318 A IL73318 A IL 73318A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
intravenous injection
emulsion form
lipid emulsion
Prior art date
Application number
IL73318A
Other languages
English (en)
Other versions
IL73318A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL73318A0 publication Critical patent/IL73318A0/xx
Publication of IL73318A publication Critical patent/IL73318A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL73318A 1983-10-28 1984-10-25 Pharmaceutical compositions in lipid emulsion form for intravenous injection and their preparation IL73318A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833339236 DE3339236A1 (de) 1983-10-28 1983-10-28 Arzneimittelzubereitung

Publications (2)

Publication Number Publication Date
IL73318A0 IL73318A0 (en) 1985-01-31
IL73318A true IL73318A (en) 1988-06-30

Family

ID=6213011

Family Applications (1)

Application Number Title Priority Date Filing Date
IL73318A IL73318A (en) 1983-10-28 1984-10-25 Pharmaceutical compositions in lipid emulsion form for intravenous injection and their preparation

Country Status (14)

Country Link
US (1) US4711902A (no)
EP (1) EP0143305A1 (no)
JP (1) JPS60115517A (no)
KR (1) KR850002953A (no)
AU (1) AU3358784A (no)
DE (1) DE3339236A1 (no)
DK (1) DK510384A (no)
ES (1) ES8604419A1 (no)
FI (1) FI844199L (no)
GR (1) GR80788B (no)
HU (1) HU193908B (no)
IL (1) IL73318A (no)
NO (1) NO844144L (no)
ZA (1) ZA848375B (no)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE3624624A1 (de) * 1986-07-18 1988-01-28 Asche Ag Xylometazolinhaltige pharmazeutische praeparate
DE3626908A1 (de) * 1986-08-08 1988-02-11 Bayer Ag Parenterale loesung
JPS6348214A (ja) * 1986-08-18 1988-02-29 Morishita Seiyaku Kk １−〔２−（２，４−ジクロロフエニル）−３−メチル−１−ペンテニル〕−１ｈ−イミダゾ−ルを含有する水中油型脂肪乳剤
DE3682208D1 (de) * 1986-12-18 1991-11-28 Kurt Heinz Bauer Gegenueber lichteinfluss stabilisiertes nifedipin-konzentrat und verfahren zu seiner herstellung.
FR2609714A1 (fr) * 1987-01-15 1988-07-22 Sanofi Sa Compositions liquides stables a base de derives antifongiques imidazoles
US4895876A (en) * 1987-03-20 1990-01-23 Air Products And Chemicals, Inc. Concentrated stable fluorochemical aqueous emulsions containing triglycerides
DE68900991D1 (de) * 1988-01-29 1992-04-23 Sankyo Co Cyclosporin-zusammensetzungen.
HU201567B (en) * 1988-07-21 1990-11-28 Gyogyszerkutato Intezet Process for production of intravenous medical compositions containing cyclosphorin
JPH02184633A (ja) * 1988-11-23 1990-07-19 Abbott Lab エイズ治療剤
CA2011063C (en) * 1989-02-28 1999-07-06 Calum B. Macfarlane Nicardipine pharmaceutical composition for parenteral administration
JP2732918B2 (ja) * 1989-10-31 1998-03-30 ライオン株式会社 口腔清浄剤組成物
JP3074731B2 (ja) * 1989-12-01 2000-08-07 日本新薬株式会社 脂肪乳剤
WO1991007964A1 (fr) * 1989-12-01 1991-06-13 Nippon Shinyaku Co., Ltd. Emulsion de graisse
TW211015B (no) * 1990-01-11 1993-08-11 Nippon Shinyaku Co Ltd
US5534502A (en) * 1990-11-06 1996-07-09 Nippon Shinyaku Co. Ltd. Process for producing fat emulsion
EP0556392A4 (en) * 1990-11-06 1994-03-17 Nippon Shinyaku Co Ltd PROCESS FOR PRODUCING A FATTY EMULSION.
WO1992018147A1 (en) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Convertible microemulsion formulations
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
SE9303744D0 (sv) * 1993-11-12 1993-11-12 Astra Ab Pharmaceutical emulsion
EP0682943B1 (de) * 1994-05-20 2003-08-20 GESELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG UND WEITERBILDUNG e.V. GMF Lormetazepamhaltige Öl-in-Wasser-Emulsion
US7205279B2 (en) * 1995-10-25 2007-04-17 Novartis Ag Pharmaceutical compositions
US5616342A (en) * 1995-04-11 1997-04-01 Pdt, Inc. Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
JP4198318B2 (ja) 1998-08-19 2008-12-17 ヤーゴテック アクチェンゲゼルシャフト プロポフォールの注射可能水性分散物
US6720001B2 (en) 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
AU2001285076A1 (en) * 2000-08-17 2002-02-25 Apollo Biopharmaceutics Inc. Formulation for administering therapeutic lipophilic molecules
EP2201965A1 (en) * 2001-11-08 2010-06-30 Ziscoat N.V. Intraluminal device with a coating containing a therapeutic agent
KR100848755B1 (ko) * 2002-01-02 2008-07-25 주식회사 두산 포스파티딜세린 함유 액상 조성물 및 그 제조방법
DK1509492T3 (da) * 2002-01-25 2011-11-28 Theravance Inc Sedative hypnotiske midler med kort virkningsvarighed til anæstesi og sedation
US6979672B2 (en) 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
DK1648413T3 (da) * 2003-07-23 2010-01-11 Theravance Inc Farmaceutiske præparater af kortvirkende sedativt sövndyssende middel
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
WO2007011385A2 (en) 2004-09-28 2007-01-25 Atrium Medical Corporation Heat cured gel and method of making
BRPI0500520A (pt) * 2005-02-16 2006-09-26 Henry Jun Suzuki uso de agentes flavorizantes aromáticos de alto ponto de fusão como agentes solubilizantes ou inibidores de cristalização em composições farmacêuticas
BRPI0501120A (pt) * 2005-02-18 2006-10-03 Henry Jun Suzuki composições farmacêuticas orais e parenterais contendo altas concentrações de agentes solubilizantes aromáticos
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
WO2007121483A2 (en) * 2006-04-18 2007-10-25 Ekr Therapeutics, Inc. Pre-mixed, ready-to-use iv bolus compositions and methods of use
US9416065B2 (en) * 2007-02-12 2016-08-16 Archer Daniels Midland Company Adjuvants and methods of using them
DE102007058785B3 (de) * 2007-12-06 2009-08-20 Hewitech Gmbh & Co. Kg Zusammensteckbare Entwässerungs- und/oder Drainagevorrichtung
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
AU2011258940B2 (en) * 2010-05-13 2014-05-29 Astrazeneca Ab Injectable emulsion of sedative hypnotic agent
EP2593141B1 (en) 2010-07-16 2018-07-04 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
CN104105472A (zh) 2011-12-20 2014-10-15 维奥姆生物科学有限公司 用于治疗真菌感染的局部油组合物
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
EA201591954A1 (ru) * 2013-04-12 2016-04-29 Вайом Байосайнсиз Пвт. Лтд. Композиция и состав противомикробных средств, способы их получения и способы лечения микробных инфекций
CN104622806B (zh) * 2015-02-04 2018-03-16 北京蓝丹医药科技有限公司 一种丙泮尼地药物组合物及其制备方法
WO2025182623A1 (ja) * 2024-02-28 2025-09-04 テクノガード株式会社 水および油難溶性薬物含有乳剤およびその製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE592881C (de) * 1932-03-27 1934-02-16 Carl Weill Dr Verfahren zur Herstellung haltbarer, fuer Injektionszwecke geeigneter Emulsionen vonin Wasser unloeslichen oder schwer loeslichen Arzneimitteln
US3149037A (en) * 1962-09-07 1964-09-15 Hoffmann La Roche Vitamin compositions
DE1792410B2 (de) * 1967-09-01 1980-03-13 Apoteksvarucentralen Vitrum Apotekareaktiebolaget, Stockholm Arzneimittelzubereitung zur intravenösen Injektion
DE1963188A1 (de) * 1969-12-17 1971-06-24 Bayer Ag Neue Cyanphenyl-1,4-dihydropyridinderivate
DE2815578C2 (de) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen Neue pharmazeutische Verwendung von Nimodipin
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
DE2837477A1 (de) * 1978-08-28 1980-03-13 Bayer Ag Sila-substituierte 1,4-dihydropyridin- derivate
DE2935573A1 (de) * 1979-09-03 1981-03-19 Lepharm- Pharmazeutische Entwicklungs- und Vertriebsgesellschaft GmbH, 5000 Köln Infusionsloesungen mit mono- und diglyceriden von fettsaeuren
JPS5665820A (en) * 1979-11-02 1981-06-03 Eisai Co Ltd Hard capsule with high content of tocopherol nicotinate
DE3106635A1 (de) * 1981-02-23 1982-09-09 Bayer Ag Antimykotisches mittel mit hoher wirkstoff-freisetzung in form von stiften

Also Published As

Publication number Publication date
AU3358784A (en) 1985-05-02
HUT36703A (en) 1985-10-28
US4711902A (en) 1987-12-08
ZA848375B (en) 1985-06-26
DK510384A (da) 1985-04-29
JPS60115517A (ja) 1985-06-22
ES8604419A1 (es) 1986-02-01
DK510384D0 (da) 1984-10-25
NO844144L (no) 1985-04-29
EP0143305A1 (de) 1985-06-05
DE3339236A1 (de) 1985-05-09
GR80788B (en) 1985-02-20
FI844199A7 (fi) 1985-04-29
FI844199L (fi) 1985-04-29
HU193908B (en) 1987-12-28
ES537022A0 (es) 1986-02-01
KR850002953A (ko) 1985-05-28
FI844199A0 (fi) 1984-10-25
IL73318A0 (en) 1985-01-31

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