IL72785A - Herpes simplex virus vaccines based on glycoproteins and process for making them - Google Patents
Herpes simplex virus vaccines based on glycoproteins and process for making themInfo
- Publication number
- IL72785A IL72785A IL72785A IL7278584A IL72785A IL 72785 A IL72785 A IL 72785A IL 72785 A IL72785 A IL 72785A IL 7278584 A IL7278584 A IL 7278584A IL 72785 A IL72785 A IL 72785A
- Authority
- IL
- Israel
- Prior art keywords
- glycoproteins
- making
- herpes simplex
- simplex virus
- virus vaccines
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 241000700584 Simplexvirus Species 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52791783A | 1983-08-30 | 1983-08-30 | |
US54755183A | 1983-10-31 | 1983-10-31 | |
US58817084A | 1984-03-09 | 1984-03-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL72785A0 IL72785A0 (en) | 1984-11-30 |
IL72785A true IL72785A (en) | 1990-07-26 |
Family
ID=27414978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL72785A IL72785A (en) | 1983-08-30 | 1984-08-27 | Herpes simplex virus vaccines based on glycoproteins and process for making them |
Country Status (13)
Country | Link |
---|---|
US (1) | US5851533A (xx) |
EP (1) | EP0139417B2 (xx) |
JP (2) | JP2599350B2 (xx) |
AU (1) | AU579323B2 (xx) |
CA (1) | CA1341181C (xx) |
DE (1) | DE3479085D1 (xx) |
DK (2) | DK172694B1 (xx) |
ES (2) | ES8605039A1 (xx) |
GR (1) | GR80220B (xx) |
HK (1) | HK98792A (xx) |
IE (1) | IE58030B1 (xx) |
IL (1) | IL72785A (xx) |
NZ (1) | NZ209308A (xx) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3228501A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung eines herpes-antigens, dazu geeignetes mittel sowie verfahren zu seiner herstellung und die verwendung dieses antigens |
NZ209308A (en) * | 1983-08-30 | 1991-08-27 | Genentech Inc | Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein |
NZ209307A (en) * | 1983-08-30 | 1990-07-26 | Genentech Inc | Diagnostic product: antigenic peptide produced by recombinant dna techniques |
US5612041A (en) * | 1984-07-17 | 1997-03-18 | Chiron Corporation | Recombinant herpes simplex gD vaccine |
US5853978A (en) * | 1985-12-04 | 1998-12-29 | Genentech, Inc. | Molecularly cloned acquired immunodeficiency syndrome polypeptides and methods of use |
US6534285B1 (en) | 1984-12-24 | 2003-03-18 | Genentech, Inc. | Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use |
CA1331355C (en) * | 1986-04-21 | 1994-08-09 | Bioenterprises Pty. Ltd | Immunopotentation |
GR862472B (en) * | 1986-09-30 | 1986-10-09 | Elliniko Institouto Paster | Determination of antibodies specific of hsv-1 herpes or hsv-2 in human serum with the elisa technic using the specific antigen of hsv-1 or hsv-2 type in semi - clean form |
IE81149B1 (en) | 1987-02-12 | 2000-05-03 | Genentech Inc | Methods and deoxyribonucleic acid for the preparation of tissue factor protein |
US5976839A (en) * | 1987-03-13 | 1999-11-02 | Bioenterprises Pty Limited | Immunopotentiation through covalent linkage between immunogen and immunopotentiating molecules |
WO1990013652A1 (en) * | 1989-05-12 | 1990-11-15 | Triton Diagnostics, Inc. | Herpes simplex virus type 2-glycoprotein g proteins and polypeptides |
EP0483281A4 (en) * | 1989-07-31 | 1992-08-12 | Basil Rapaport | Recombinant human thyroid peroxidase |
WO1993005072A1 (en) * | 1991-08-28 | 1993-03-18 | Basil Rapoport | Disease associated human autoantibodies specific for human thyroid peroxidase |
EP0541692B1 (en) * | 1990-08-02 | 1999-05-06 | Chiron Corporation | Herpes simplex virus vp16 vaccines |
GB9105992D0 (en) * | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccine |
ES2108278T3 (es) | 1992-06-25 | 1997-12-16 | Smithkline Beecham Biolog | Composicion de vacuna con coadyuvantes. |
WO1999005161A1 (en) | 1997-07-25 | 1999-02-04 | Ligand Pharmaceuticals Incorporated | HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA (PPARη) GENE REGULATORY SEQUENCES AND USES THEREFOR |
US6692752B1 (en) | 1999-09-08 | 2004-02-17 | Smithkline Beecham Biologicals S.A. | Methods of treating human females susceptible to HSV infection |
WO2002016420A2 (en) * | 2000-08-01 | 2002-02-28 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Antiviral compounds derived from the hsv gd protein and methods |
ATE469915T1 (de) | 2001-07-27 | 2010-06-15 | Novartis Vaccines & Diagnostic | Antikörper gegen das meningokokken adhäsin app |
JP2004099584A (ja) * | 2002-05-02 | 2004-04-02 | Keio Gijuku | Hsvを用いた抗腫瘍剤 |
JP2007505147A (ja) | 2003-09-12 | 2007-03-08 | アンティジェニクス インコーポレーテッド | 単純ヘルペスウイルス感染の治療および予防用ワクチン |
BRPI0518284A2 (pt) | 2004-11-24 | 2008-11-11 | Shell Int Research | aparelhos para separar substancialmente um fluxo em duas fases em um componente gasoso e um componente lÍquido, para separar substancialmente um fluxo de mistura em um componente lÍquido e pelo menos outro componente lÍquido e um componente gasoso e para separar substancialmente um fluxo de mistura em partes componentes com base nas densidades das partes componentes, sistema para separar substancialmente um fluxo de mistura em partes componentes, e, mÉtodos para separar substancialmente um fluxo tampço e para projetar um separador para separar substancialmente um fluxo tampço |
US8865185B2 (en) | 2006-09-08 | 2014-10-21 | The Trustees Of The University Of Pennsylvania | Methods of use for HSV-1 and HSV-2 vaccines |
US8871223B2 (en) | 2006-09-08 | 2014-10-28 | The Trustees Of The University Of Pennsylvania | HSV-1 and HSV-2 vaccines and methods of use thereof |
CN101616688B (zh) * | 2006-12-28 | 2013-12-11 | 宾夕法尼亚大学理事会 | 单纯疱疹病毒联合亚单位疫苗及其使用方法 |
US10478490B2 (en) | 2006-12-28 | 2019-11-19 | The Trustees Of The University Of Pennsylvania | Herpes simplex virus combined subunit vaccines and methods of use thereof |
GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
RU2585961C9 (ru) * | 2009-05-22 | 2016-12-27 | Дженосеа Биосайенсиз Инк. | Вакцины против вируса простого герпеса 2 типа: композиции и способы запуска иммунного ответа |
DE102009056884B4 (de) | 2009-12-03 | 2021-03-18 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
MX2012005598A (es) | 2009-12-03 | 2012-05-29 | Novartis Ag | Filtracion hidrofilica durante la fabricacion de adyuvantes de vacuna. |
DE102009056883B4 (de) | 2009-12-03 | 2012-08-16 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
ES2573710T3 (es) | 2009-12-03 | 2016-06-09 | Novartis Ag | Circulación de componentes durante la homogeneización y de microfluidización de emulsiones |
DE102009056871A1 (de) | 2009-12-03 | 2011-06-22 | Novartis AG, 4056 | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
PT2380558E (pt) | 2009-12-03 | 2012-11-27 | Novartis Ag | Disposição de câmaras de interacção e de contrapressão para microfluidização |
PT3489211T (pt) | 2010-05-12 | 2020-09-22 | Novartis Ag | Métodos aperfeiçoados para preparar esqualeno |
AU2011336894B2 (en) | 2010-11-24 | 2016-11-17 | Genocea Biosciences, Inc. | Vaccines against Herpes Simplex Virus type 2: compositions and methods for eliciting an immune response |
CA2885693C (en) | 2011-11-23 | 2020-07-28 | Genocea Biosciences, Inc. | Nucleic acid vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response |
EP2850431B1 (en) | 2012-05-16 | 2018-04-18 | Immune Design Corp. | Vaccines for hsv-2 |
CN106456805B (zh) | 2014-03-03 | 2020-01-10 | 阿尔伯特爱因斯坦医学院公司 | 重组单纯疱疹病毒2(hsv-2)疫苗载体 |
ES2861806T3 (es) | 2014-12-02 | 2021-10-06 | Novartis Ag | Fabricación de composiciones que contienen tensioactivo |
WO2018064232A1 (en) | 2016-09-28 | 2018-04-05 | Genocea Biosciences, Inc. | Methods and compositions for treating herpes |
US20230218526A1 (en) | 2020-06-30 | 2023-07-13 | Seqirus UK Limited | Cold filtration of oil-in-water emulsion adjuvants |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI66020C (fi) * | 1977-09-19 | 1984-08-10 | Merck & Co Inc | Foerfarande foer framstaellning av antigeniska immunogeniska subunits av hsv-1 och hsv-2 |
US4374127A (en) * | 1977-09-19 | 1983-02-15 | Merck & Co., Inc. | Herpes sub unit vaccine |
DE2949031A1 (de) * | 1978-12-15 | 1980-07-17 | Sandoz Ag | Vakzine |
EP0038765B1 (fr) * | 1980-04-22 | 1987-09-02 | Institut Pasteur | Vaccin contre l'hépatite virale B, procédé et cellules eucaryotes transformées pour la production de ce vaccin |
FR2480780B1 (fr) * | 1980-04-22 | 1985-12-06 | Pasteur Institut | Procede de transformation de cellules, notamment eucaryotes, par un adn circulaire tel que celui du virus de l'hepatite b et preparations contenant les produits d'expression desdits adn |
US4317811A (en) * | 1980-09-11 | 1982-03-02 | Merck & Co., Inc. | Herpes simplex type 1 subunit vaccine |
WO1982003088A1 (en) * | 1981-03-09 | 1982-09-16 | Corp Cetus | Vaccines |
EP0068693A3 (en) | 1981-06-16 | 1983-07-20 | Genentech, Inc. | Production of foot and mouth disease vaccine from microbially expressed antigens |
ZW18282A1 (en) | 1981-08-31 | 1983-03-23 | Genentech Inc | Preparation of polypeptides in vertebrate cell culture |
US4442205A (en) * | 1981-09-22 | 1984-04-10 | The United States Of America As Represented By The Department Of Health And Human Services | Simian virus recombinant that directs the synthesis of hepatitis B surface antigen |
US4593002A (en) * | 1982-01-11 | 1986-06-03 | Salk Institute Biotechnology/Industrial Associates, Inc. | Viruses with recombinant surface proteins |
US4762708A (en) * | 1982-02-18 | 1988-08-09 | University Patents, Inc. | Materials and methods for herpes simplex virus vaccination |
US4891315A (en) * | 1982-10-25 | 1990-01-02 | American Cyanamid Company | Production of herpes simplex viral porteins |
AU1678783A (en) * | 1982-07-20 | 1984-01-26 | Molecular Genetics, Inc. | Production of herpes simplex viral proteins |
PT77014B (en) * | 1982-07-20 | 1986-01-24 | Molecular Genetics Inc | Production of herpes simplex viral proteins |
US4818694A (en) * | 1982-07-20 | 1989-04-04 | American Cyanamid Company | Production of herpes simplex viral protein |
DE3228501A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung eines herpes-antigens, dazu geeignetes mittel sowie verfahren zu seiner herstellung und die verwendung dieses antigens |
DK305784A (da) * | 1983-06-23 | 1984-12-24 | Stanley Person | Ikke-glycosyleret aminosyrekaede af glycoprotein b fra herpes virus type 1 og 2 |
NZ209308A (en) * | 1983-08-30 | 1991-08-27 | Genentech Inc | Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein |
US4855224A (en) * | 1984-03-09 | 1989-08-08 | Genentech, Inc. | Molecularly cloned diagnostic product and method of use |
EP0628633B1 (en) * | 1984-04-06 | 2003-01-08 | Chiron Corporation | Recombinant herpes simplex gB-gD vaccine |
US4618578A (en) * | 1984-07-17 | 1986-10-21 | Chiron Corporation | Expression of glycoprotein D of herpes simplex virus |
US4859587A (en) * | 1984-06-04 | 1989-08-22 | Institut Merieux | Recombinant herpes simplex viruses, vaccines and methods |
JPS615786A (ja) * | 1984-06-19 | 1986-01-11 | Chemo Sero Therapeut Res Inst | 単純ヘルペスウイルス遺伝子を組込んだ組換えdna、形質転換動物細胞および単純ヘルペスウイルス蛋白質の製法 |
EP0170169B1 (en) * | 1984-07-20 | 1991-03-20 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Recombinant dna containing a herpes simplex virus gene or a fragment thereof, yeast transformed with said recombinant dna, and method for the production of herpes simplex virus proteins |
-
1984
- 1984-08-22 NZ NZ209308A patent/NZ209308A/xx unknown
- 1984-08-27 CA CA000461897A patent/CA1341181C/en not_active Expired - Lifetime
- 1984-08-27 IL IL72785A patent/IL72785A/xx not_active IP Right Cessation
- 1984-08-27 AU AU32423/84A patent/AU579323B2/en not_active Expired
- 1984-08-28 GR GR80220A patent/GR80220B/el unknown
- 1984-08-29 IE IE221084A patent/IE58030B1/en not_active IP Right Cessation
- 1984-08-29 DE DE8484305909T patent/DE3479085D1/de not_active Expired
- 1984-08-29 EP EP84305909A patent/EP0139417B2/en not_active Expired - Lifetime
- 1984-08-29 DK DK198404122A patent/DK172694B1/da not_active IP Right Cessation
- 1984-08-30 JP JP59183623A patent/JP2599350B2/ja not_active Expired - Lifetime
- 1984-08-30 ES ES535554A patent/ES8605039A1/es not_active Expired
-
1986
- 1986-02-28 ES ES552539A patent/ES8705036A1/es not_active Expired
-
1992
- 1992-12-10 HK HK987/92A patent/HK98792A/xx not_active IP Right Cessation
-
1994
- 1994-12-15 US US08/357,084 patent/US5851533A/en not_active Expired - Lifetime
-
1995
- 1995-08-30 JP JP7222311A patent/JPH08253428A/ja active Pending
-
1997
- 1997-01-24 DK DK009197A patent/DK9197A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2599350B2 (ja) | 1997-04-09 |
DK9197A (da) | 1997-01-24 |
JPH08253428A (ja) | 1996-10-01 |
JPS60155128A (ja) | 1985-08-15 |
NZ209308A (en) | 1991-08-27 |
DK412284A (da) | 1985-04-11 |
ES8605039A1 (es) | 1986-03-16 |
HK98792A (en) | 1992-12-18 |
DK412284D0 (da) | 1984-08-29 |
EP0139417B1 (en) | 1989-07-26 |
ES535554A0 (es) | 1986-03-16 |
AU579323B2 (en) | 1988-11-24 |
IE58030B1 (en) | 1993-06-16 |
CA1341181C (en) | 2001-02-20 |
DK172694B1 (da) | 1999-05-31 |
ES552539A0 (es) | 1987-05-01 |
US5851533A (en) | 1998-12-22 |
EP0139417B2 (en) | 1999-03-17 |
IE842210L (en) | 1985-02-28 |
EP0139417A1 (en) | 1985-05-02 |
ES8705036A1 (es) | 1987-05-01 |
DE3479085D1 (en) | 1989-08-31 |
AU3242384A (en) | 1985-03-07 |
IL72785A0 (en) | 1984-11-30 |
GR80220B (en) | 1984-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
RH | Patent void | ||
KB | Patent renewed | ||
EXP | Patent expired |