EP0483281A4 - Recombinant human thyroid peroxidase - Google Patents

Recombinant human thyroid peroxidase

Info

Publication number
EP0483281A4
EP0483281A4 EP19900912413 EP90912413A EP0483281A4 EP 0483281 A4 EP0483281 A4 EP 0483281A4 EP 19900912413 EP19900912413 EP 19900912413 EP 90912413 A EP90912413 A EP 90912413A EP 0483281 A4 EP0483281 A4 EP 0483281A4
Authority
EP
European Patent Office
Prior art keywords
recombinant human
human thyroid
thyroid peroxidase
peroxidase
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900912413
Other versions
EP0483281A1 (en
Inventor
Basil Rapaport
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0483281A1 publication Critical patent/EP0483281A1/en
Publication of EP0483281A4 publication Critical patent/EP0483281A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP19900912413 1989-07-31 1990-07-31 Recombinant human thyroid peroxidase Withdrawn EP0483281A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US38804489A 1989-07-31 1989-07-31
US388044 1989-07-31
US47207090A 1990-01-30 1990-01-30
US472070 1990-01-30

Publications (2)

Publication Number Publication Date
EP0483281A1 EP0483281A1 (en) 1992-05-06
EP0483281A4 true EP0483281A4 (en) 1992-08-12

Family

ID=27012119

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900912413 Withdrawn EP0483281A4 (en) 1989-07-31 1990-07-31 Recombinant human thyroid peroxidase

Country Status (4)

Country Link
EP (1) EP0483281A4 (en)
JP (1) JPH05501951A (en)
AU (1) AU6161390A (en)
WO (1) WO1991002061A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2024562C (en) * 1989-09-05 2000-09-26 Shinya Yamashita Cho cells transformed with a recombinant plasmid expressing human thyroid peroxidase and preparation thereof
JPH07506960A (en) * 1991-08-28 1995-08-03 ニコルス・インスティチュート・ダイアグノスティクス Disease-associated human antibodies specific for human thyroid peroxidase
US5705400A (en) * 1992-03-07 1998-01-06 Rsr Limited Assay for adrenal autoantigen
US5998153A (en) * 1992-05-19 1999-12-07 The Regents Of The University Of Michigan Thyroid peroxidase epitopic regions
DE4343255A1 (en) * 1993-07-13 1995-06-22 Henning Berlin Gmbh Method for the quantitative determination of human thyroid peroxidase and kit for carrying out the method
US20070037186A1 (en) 2005-05-20 2007-02-15 Yuqiu Jiang Thyroid fine needle aspiration molecular assay
JP6277684B2 (en) * 2013-11-18 2018-02-14 大日本印刷株式会社 Method for producing cell laminate
JP2018078906A (en) * 2018-01-17 2018-05-24 大日本印刷株式会社 Cell laminate production method
CN112501141A (en) * 2020-10-22 2021-03-16 重庆中元汇吉生物技术有限公司 Reagent for increasing yield of human thyroid peroxidase and expression method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0421139A2 (en) * 1989-09-05 1991-04-10 Nippon Suisan Kaisha, Ltd. Process for the production of human thyroid peroxidase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ209308A (en) * 1983-08-30 1991-08-27 Genentech Inc Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0421139A2 (en) * 1989-09-05 1991-04-10 Nippon Suisan Kaisha, Ltd. Process for the production of human thyroid peroxidase

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
FEBS LETTERS. vol. 250, no. 2, 3 July 1989, AMSTERDAM NL pages 377 - 380; SHIOKO KIMURA ET AL.: 'cDNA-directed expression of human thyroid peroxidase' *
See also references of WO9102061A1 *
THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM vol. 70, no. 3, March 1990, pages 724 - 728; KEITH D. KAUFMAN ET AL.: 'Recombinant Human Thyroid Peroxidase Generated in Eukaryotic Cells: A Source of Specific Antigen for the Immunological Assay of Antimicrosomal Antibodies in the Sera of Patients with Autoimmune Thyroid Disease' *
THE JOURNAL OF CLINICAL INVESTIGATION vol. 84, no. 2, August 1989, pages 394 - 403; KEITH D. KAUFMAN ET AL.: 'Generation of Recombinant, Enzymatically Active Human Thyroid Peroxidase and its Recognition by Antibodies in the Sera of Patients with Hashimoto's Thyroiditis' *

Also Published As

Publication number Publication date
WO1991002061A1 (en) 1991-02-21
AU6161390A (en) 1991-03-11
JPH05501951A (en) 1993-04-15
EP0483281A1 (en) 1992-05-06

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19920130

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18D Application deemed to be withdrawn

Effective date: 19960109