IL72785A - Herpes simplex virus vaccines based on glycoproteins and process for making them - Google Patents
Herpes simplex virus vaccines based on glycoproteins and process for making themInfo
- Publication number
- IL72785A IL72785A IL72785A IL7278584A IL72785A IL 72785 A IL72785 A IL 72785A IL 72785 A IL72785 A IL 72785A IL 7278584 A IL7278584 A IL 7278584A IL 72785 A IL72785 A IL 72785A
- Authority
- IL
- Israel
- Prior art keywords
- glycoproteins
- making
- herpes simplex
- simplex virus
- virus vaccines
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 241000700584 Simplexvirus Species 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52791783A | 1983-08-30 | 1983-08-30 | |
US54755183A | 1983-10-31 | 1983-10-31 | |
US58817084A | 1984-03-09 | 1984-03-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL72785A0 IL72785A0 (en) | 1984-11-30 |
IL72785A true IL72785A (en) | 1990-07-26 |
Family
ID=27414978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL72785A IL72785A (en) | 1983-08-30 | 1984-08-27 | Herpes simplex virus vaccines based on glycoproteins and process for making them |
Country Status (13)
Country | Link |
---|---|
US (1) | US5851533A (da) |
EP (1) | EP0139417B2 (da) |
JP (2) | JP2599350B2 (da) |
AU (1) | AU579323B2 (da) |
CA (1) | CA1341181C (da) |
DE (1) | DE3479085D1 (da) |
DK (2) | DK172694B1 (da) |
ES (2) | ES8605039A1 (da) |
GR (1) | GR80220B (da) |
HK (1) | HK98792A (da) |
IE (1) | IE58030B1 (da) |
IL (1) | IL72785A (da) |
NZ (1) | NZ209308A (da) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3228501A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung eines herpes-antigens, dazu geeignetes mittel sowie verfahren zu seiner herstellung und die verwendung dieses antigens |
NZ209307A (en) * | 1983-08-30 | 1990-07-26 | Genentech Inc | Diagnostic product: antigenic peptide produced by recombinant dna techniques |
NZ209308A (en) * | 1983-08-30 | 1991-08-27 | Genentech Inc | Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein |
US5612041A (en) * | 1984-07-17 | 1997-03-18 | Chiron Corporation | Recombinant herpes simplex gD vaccine |
US5853978A (en) * | 1985-12-04 | 1998-12-29 | Genentech, Inc. | Molecularly cloned acquired immunodeficiency syndrome polypeptides and methods of use |
US6534285B1 (en) | 1984-12-24 | 2003-03-18 | Genentech, Inc. | Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use |
CA1331355C (en) * | 1986-04-21 | 1994-08-09 | Bioenterprises Pty. Ltd | Immunopotentation |
GR862472B (en) * | 1986-09-30 | 1986-10-09 | Elliniko Institouto Paster | Determination of antibodies specific of hsv-1 herpes or hsv-2 in human serum with the elisa technic using the specific antigen of hsv-1 or hsv-2 type in semi - clean form |
IE81149B1 (en) | 1987-02-12 | 2000-05-03 | Genentech Inc | Methods and deoxyribonucleic acid for the preparation of tissue factor protein |
US5976839A (en) * | 1987-03-13 | 1999-11-02 | Bioenterprises Pty Limited | Immunopotentiation through covalent linkage between immunogen and immunopotentiating molecules |
WO1990013652A1 (en) * | 1989-05-12 | 1990-11-15 | Triton Diagnostics, Inc. | Herpes simplex virus type 2-glycoprotein g proteins and polypeptides |
AU6161390A (en) * | 1989-07-31 | 1991-03-11 | Basil Rapaport | Recombinant human thyroid peroxidase |
CA2088600C (en) * | 1990-08-02 | 1999-11-16 | Rae L. Burke | Herpes simplex virus vp16 vaccines |
GB9105992D0 (en) * | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccine |
JPH07506960A (ja) * | 1991-08-28 | 1995-08-03 | ニコルス・インスティチュート・ダイアグノスティクス | ヒト甲状腺ペルオキシダーゼに特異的な疾病関連性ヒト抗体 |
DK0671948T3 (da) * | 1992-06-25 | 1997-09-01 | Smithkline Beecham Biolog | Vaccinepræparat indeholdende adjuvanser |
WO1999005161A1 (en) | 1997-07-25 | 1999-02-04 | Ligand Pharmaceuticals Incorporated | HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA (PPARη) GENE REGULATORY SEQUENCES AND USES THEREFOR |
US6692752B1 (en) | 1999-09-08 | 2004-02-17 | Smithkline Beecham Biologicals S.A. | Methods of treating human females susceptible to HSV infection |
AU2001286407A1 (en) * | 2000-08-01 | 2002-03-04 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Antiviral compounds derived from the hsv gd protein and methods |
JP4592284B2 (ja) | 2001-07-27 | 2010-12-01 | カイロン ソチエタ ア レスポンサビリタ リミタータ | 髄膜炎菌付着因子 |
JP2004099584A (ja) * | 2002-05-02 | 2004-04-02 | Keio Gijuku | Hsvを用いた抗腫瘍剤 |
CA2538794C (en) | 2003-09-12 | 2016-04-19 | Antigenics, Inc. | Vaccine for treatment and prevention of herpes simplex virus infection |
BRPI0518284A2 (pt) | 2004-11-24 | 2008-11-11 | Shell Int Research | aparelhos para separar substancialmente um fluxo em duas fases em um componente gasoso e um componente lÍquido, para separar substancialmente um fluxo de mistura em um componente lÍquido e pelo menos outro componente lÍquido e um componente gasoso e para separar substancialmente um fluxo de mistura em partes componentes com base nas densidades das partes componentes, sistema para separar substancialmente um fluxo de mistura em partes componentes, e, mÉtodos para separar substancialmente um fluxo tampço e para projetar um separador para separar substancialmente um fluxo tampço |
CN101583381B (zh) | 2006-09-08 | 2014-05-07 | 宾夕法尼亚大学董事会 | Hsv-1和hsv-2疫苗和其使用方法 |
US8865185B2 (en) | 2006-09-08 | 2014-10-21 | The Trustees Of The University Of Pennsylvania | Methods of use for HSV-1 and HSV-2 vaccines |
JP6144448B2 (ja) * | 2006-12-28 | 2017-06-07 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 単純ヘルペスウイルス複合サブユニットワクチンおよびその使用方法 |
US10478490B2 (en) | 2006-12-28 | 2019-11-19 | The Trustees Of The University Of Pennsylvania | Herpes simplex virus combined subunit vaccines and methods of use thereof |
GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
JP5771605B2 (ja) * | 2009-05-22 | 2015-09-02 | ジェノセア バイオサイエンシーズ, インコーポレイテッド | 単純ヘルペスウイルス2型に対するワクチン:免疫応答を誘発する組成物および方法 |
DE102009056883B4 (de) | 2009-12-03 | 2012-08-16 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
DE102009056884B4 (de) | 2009-12-03 | 2021-03-18 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
JP5754860B2 (ja) | 2009-12-03 | 2015-07-29 | ノバルティス アーゲー | ワクチンアジュバントの製造の間の親水性濾過 |
DE102009056871A1 (de) | 2009-12-03 | 2011-06-22 | Novartis AG, 4056 | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
US8895629B2 (en) | 2009-12-03 | 2014-11-25 | Novartis Ag | Circulation of components during homogenization of emulsions |
WO2011067672A2 (en) | 2009-12-03 | 2011-06-09 | Novartis Ag | Arranging interaction and back pressure chambers for microfluidization |
SI2569267T1 (sl) | 2010-05-12 | 2014-03-31 | Novartis Ag | Izboljšani postopki za pripravo skvalena |
EP2643014A4 (en) | 2010-11-24 | 2015-11-11 | Genocea Biosciences Inc | HERPES SIMPLEX TYPE 2 VIRUS VACCINES: COMPOSITIONS AND METHODS FOR STIMULATING AN IMMUNE RESPONSE |
EP2782597B1 (en) | 2011-11-23 | 2022-04-13 | Genocea Biosciences, Inc. | Nucleic acid vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response |
EA034351B1 (ru) | 2012-05-16 | 2020-01-30 | Иммьюн Дизайн Корп. | Трехкомпонентная вакцина против впг-2 и способы ее применения |
CN110938604B (zh) * | 2014-03-03 | 2024-04-05 | 阿尔伯特爱因斯坦医学院 | 重组单纯疱疹病毒2(hsv-2)疫苗载体 |
ES2721306T3 (es) | 2014-12-02 | 2019-07-30 | Novartis Ag | Fabricación de composiciones que contienen tensioactivo |
EP3519427A4 (en) | 2016-09-28 | 2020-03-11 | Genocea Biosciences Inc. | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HERPES |
JP2023532944A (ja) | 2020-06-30 | 2023-08-01 | セキラス ユーケー リミテッド | 水中油型エマルジョンアジュバントの低温濾過 |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4374127A (en) * | 1977-09-19 | 1983-02-15 | Merck & Co., Inc. | Herpes sub unit vaccine |
FI66020C (fi) * | 1977-09-19 | 1984-08-10 | Merck & Co Inc | Foerfarande foer framstaellning av antigeniska immunogeniska subunits av hsv-1 och hsv-2 |
DE2949031A1 (de) * | 1978-12-15 | 1980-07-17 | Sandoz Ag | Vakzine |
DE3176404D1 (en) * | 1980-04-22 | 1987-10-08 | Pasteur Institut | Vaccine against viral hepatitis b, method and transformed eucaryotic cells for the preparation of this vaccine |
FR2480780B1 (fr) * | 1980-04-22 | 1985-12-06 | Pasteur Institut | Procede de transformation de cellules, notamment eucaryotes, par un adn circulaire tel que celui du virus de l'hepatite b et preparations contenant les produits d'expression desdits adn |
US4317811A (en) * | 1980-09-11 | 1982-03-02 | Merck & Co., Inc. | Herpes simplex type 1 subunit vaccine |
NZ199866A (en) * | 1981-03-09 | 1984-11-09 | Cetus Corp | Vaccine for prevention of gastroenteric disease:non-pathogenic strain genetically engineered to comprise genes for adhesin and/or toxoids |
GB2103622B (en) | 1981-06-16 | 1986-01-15 | Genentech Inc | Production of foot and mouth disease vaccine from microbially expressed antigens |
ZW18282A1 (en) | 1981-08-31 | 1983-03-23 | Genentech Inc | Preparation of polypeptides in vertebrate cell culture |
US4442205A (en) * | 1981-09-22 | 1984-04-10 | The United States Of America As Represented By The Department Of Health And Human Services | Simian virus recombinant that directs the synthesis of hepatitis B surface antigen |
US4593002A (en) * | 1982-01-11 | 1986-06-03 | Salk Institute Biotechnology/Industrial Associates, Inc. | Viruses with recombinant surface proteins |
US4762708A (en) * | 1982-02-18 | 1988-08-09 | University Patents, Inc. | Materials and methods for herpes simplex virus vaccination |
US4818694A (en) * | 1982-07-20 | 1989-04-04 | American Cyanamid Company | Production of herpes simplex viral protein |
AU1678783A (en) * | 1982-07-20 | 1984-01-26 | Molecular Genetics, Inc. | Production of herpes simplex viral proteins |
PT77014B (en) * | 1982-07-20 | 1986-01-24 | Molecular Genetics Inc | Production of herpes simplex viral proteins |
US4891315A (en) * | 1982-10-25 | 1990-01-02 | American Cyanamid Company | Production of herpes simplex viral porteins |
DE3228501A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung eines herpes-antigens, dazu geeignetes mittel sowie verfahren zu seiner herstellung und die verwendung dieses antigens |
DE3461928D1 (en) * | 1983-06-23 | 1987-02-12 | Person Stanley | Immunologically reactive non-glycosylated amino acid chains of glycoprotein b of herpes virus types 1 and 2 |
NZ209308A (en) * | 1983-08-30 | 1991-08-27 | Genentech Inc | Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein |
US4855224A (en) * | 1984-03-09 | 1989-08-08 | Genentech, Inc. | Molecularly cloned diagnostic product and method of use |
US4618578A (en) * | 1984-07-17 | 1986-10-21 | Chiron Corporation | Expression of glycoprotein D of herpes simplex virus |
EP0628633B1 (en) * | 1984-04-06 | 2003-01-08 | Chiron Corporation | Recombinant herpes simplex gB-gD vaccine |
US4859587A (en) * | 1984-06-04 | 1989-08-22 | Institut Merieux | Recombinant herpes simplex viruses, vaccines and methods |
JPS615786A (ja) * | 1984-06-19 | 1986-01-11 | Chemo Sero Therapeut Res Inst | 単純ヘルペスウイルス遺伝子を組込んだ組換えdna、形質転換動物細胞および単純ヘルペスウイルス蛋白質の製法 |
DE3582200D1 (de) * | 1984-07-20 | 1991-04-25 | Chemo Sero Therapeut Res Inst | Rekombinante dns, enthaltend ein herpes-simplex-virus-gen oder ein fragment davon, hefe transformiert mit dieser rekombinanten dns und verfahren zur herstellung von herpes-simplex-virus-proteinen. |
-
1984
- 1984-08-22 NZ NZ209308A patent/NZ209308A/xx unknown
- 1984-08-27 IL IL72785A patent/IL72785A/xx not_active IP Right Cessation
- 1984-08-27 AU AU32423/84A patent/AU579323B2/en not_active Expired
- 1984-08-27 CA CA000461897A patent/CA1341181C/en not_active Expired - Lifetime
- 1984-08-28 GR GR80220A patent/GR80220B/el unknown
- 1984-08-29 IE IE221084A patent/IE58030B1/en not_active IP Right Cessation
- 1984-08-29 EP EP84305909A patent/EP0139417B2/en not_active Expired - Lifetime
- 1984-08-29 DK DK198404122A patent/DK172694B1/da not_active IP Right Cessation
- 1984-08-29 DE DE8484305909T patent/DE3479085D1/de not_active Expired
- 1984-08-30 ES ES535554A patent/ES8605039A1/es not_active Expired
- 1984-08-30 JP JP59183623A patent/JP2599350B2/ja not_active Expired - Lifetime
-
1986
- 1986-02-28 ES ES552539A patent/ES8705036A1/es not_active Expired
-
1992
- 1992-12-10 HK HK987/92A patent/HK98792A/xx not_active IP Right Cessation
-
1994
- 1994-12-15 US US08/357,084 patent/US5851533A/en not_active Expired - Lifetime
-
1995
- 1995-08-30 JP JP7222311A patent/JPH08253428A/ja active Pending
-
1997
- 1997-01-24 DK DK009197A patent/DK9197A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL72785A0 (en) | 1984-11-30 |
IE58030B1 (en) | 1993-06-16 |
NZ209308A (en) | 1991-08-27 |
JPS60155128A (ja) | 1985-08-15 |
DK412284A (da) | 1985-04-11 |
AU3242384A (en) | 1985-03-07 |
AU579323B2 (en) | 1988-11-24 |
DK172694B1 (da) | 1999-05-31 |
DE3479085D1 (en) | 1989-08-31 |
EP0139417A1 (en) | 1985-05-02 |
US5851533A (en) | 1998-12-22 |
DK9197A (da) | 1997-01-24 |
ES8605039A1 (es) | 1986-03-16 |
JP2599350B2 (ja) | 1997-04-09 |
JPH08253428A (ja) | 1996-10-01 |
CA1341181C (en) | 2001-02-20 |
ES552539A0 (es) | 1987-05-01 |
ES535554A0 (es) | 1986-03-16 |
EP0139417B1 (en) | 1989-07-26 |
IE842210L (en) | 1985-02-28 |
EP0139417B2 (en) | 1999-03-17 |
ES8705036A1 (es) | 1987-05-01 |
DK412284D0 (da) | 1984-08-29 |
HK98792A (en) | 1992-12-18 |
GR80220B (en) | 1984-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
RH | Patent void | ||
KB | Patent renewed | ||
EXP | Patent expired |