IL67206A0 - Bicyclic compounds,their preparation and pharmaceutical compositions containing them - Google Patents
Bicyclic compounds,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL67206A0 IL67206A0 IL67206A IL6720682A IL67206A0 IL 67206 A0 IL67206 A0 IL 67206A0 IL 67206 A IL67206 A IL 67206A IL 6720682 A IL6720682 A IL 6720682A IL 67206 A0 IL67206 A0 IL 67206A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- bicyclic compounds
- bicyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8133930 | 1981-11-10 | ||
GB8133942 | 1981-11-10 | ||
GB8213846 | 1982-05-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL67206A0 true IL67206A0 (en) | 1983-03-31 |
Family
ID=27261362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL67206A IL67206A0 (en) | 1981-11-10 | 1982-11-09 | Bicyclic compounds,their preparation and pharmaceutical compositions containing them |
Country Status (17)
Country | Link |
---|---|
US (1) | US4603139A (pt) |
EP (1) | EP0079083B1 (pt) |
KR (1) | KR890000022B1 (pt) |
AR (1) | AR241247A1 (pt) |
AU (1) | AU9030682A (pt) |
DD (1) | DD205904A5 (pt) |
DK (1) | DK161325C (pt) |
ES (2) | ES8401486A1 (pt) |
FI (1) | FI79312C (pt) |
GB (1) | GB2113675B (pt) |
GR (1) | GR76746B (pt) |
IE (1) | IE56478B1 (pt) |
IL (1) | IL67206A0 (pt) |
MC (1) | MC1491A1 (pt) |
NO (1) | NO158100C (pt) |
PH (1) | PH22764A (pt) |
PT (1) | PT75820B (pt) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0072926B1 (de) * | 1981-08-19 | 1986-09-24 | MERCK PATENT GmbH | 2-Aryl-imidazopyridine |
US4758574A (en) * | 1982-05-03 | 1988-07-19 | Eli Lilly And Company | 2-phenylimidazio (4,5-c) pyridines |
RO86850B (ro) * | 1982-05-03 | 1985-05-31 | Eli Lilly And Company | Procedeu pentru prepararea unor 2-fenilimidazo [4,5 c] piridine |
US4904785A (en) * | 1982-05-03 | 1990-02-27 | Eli Lilly And Company | 2-phenylimidazo[4,5-c]pyridines |
DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
DE3324115A1 (de) * | 1983-07-05 | 1985-01-17 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
US4515796A (en) * | 1983-09-08 | 1985-05-07 | Eli Lilly And Company | Certain naphthalenyl imidazo compounds and their pharmaceutical use |
US4533734A (en) * | 1983-11-10 | 1985-08-06 | Eli Lilly And Company | Inotropic agents |
DE3346602A1 (de) * | 1983-12-23 | 1985-07-11 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazo(4,5-c)pyridin-one, deren herstellung und diese verbindungen enthaltende arzneimittel |
DE3347290A1 (de) * | 1983-12-28 | 1985-07-11 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue 2-phenyl-imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
ZA851236B (en) * | 1984-02-24 | 1986-09-24 | Lilly Co Eli | 2-arylimidazo 4,5-cpyridines |
US4578387A (en) * | 1984-03-05 | 1986-03-25 | Eli Lilly And Company | Inotropic agents |
DE3445299A1 (de) * | 1984-12-12 | 1986-06-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
IL78241A0 (en) * | 1985-03-29 | 1986-07-31 | Lilly Co Eli | Synthesis of inotropic imidazo(4,5-c)pyridine |
DE3522230A1 (de) * | 1985-06-21 | 1987-01-02 | Thomae Gmbh Dr K | Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
US4740599A (en) * | 1986-10-03 | 1988-04-26 | Eli Lilly And Company | Synthesis of alkylsulfinyl substituted 2-phenylimidazo(4,5-c)pyridines |
ZA889365B (en) * | 1987-12-22 | 1990-08-29 | Lilly Co Eli | Hydrates of andinotropic agent |
GB8822170D0 (en) * | 1988-09-21 | 1988-10-26 | Pfizer Ltd | Therapeutic agents |
BR9106433A (pt) * | 1990-05-09 | 1993-05-04 | Pfizer | Imidazo (4,5-c) piridinas com atividade antagonista ao paf |
DE4324580A1 (de) * | 1993-07-22 | 1995-01-26 | Thomae Gmbh Dr K | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
US6020340A (en) * | 1996-05-15 | 2000-02-01 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Imidazopyridines |
DE59711147D1 (de) * | 1996-11-11 | 2004-01-29 | Altana Pharma Ag | Neue Imidazo- und Oxazolopyridine als Phosphodiesterase Inhibitoren. |
EP1294718A2 (en) * | 2000-06-14 | 2003-03-26 | Warner-Lambert Company Llc | 6,5-fused bicyclic heterocycles |
ATE340175T1 (de) * | 2003-02-25 | 2006-10-15 | Altana Pharma Ag | Imidazo(4,5-böchinolinderivate und ihre verwendung als inhibitoren der induzierbaren no- synthase |
KR20060087386A (ko) * | 2005-01-28 | 2006-08-02 | 주식회사 대웅제약 | 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물 |
WO2007034277A1 (en) * | 2005-09-19 | 2007-03-29 | Pfizer Products Inc. | Aryl substituted imidazo [4,5-c] pyridine compounds as c3a receptor antagonists |
BRPI0914404A2 (pt) | 2008-10-31 | 2019-03-06 | Genentech Inc | "compostos, composição farmacêutica e método para tratar ou atenuar a gravidade de uma doença ou condição responsiva à inibição da atividade jak quinase em um paciente" |
UA110324C2 (en) | 2009-07-02 | 2015-12-25 | Genentech Inc | Jak inhibitory compounds based on pyrazolo pyrimidine |
DK2987487T3 (da) * | 2009-08-10 | 2020-12-07 | Samumed Llc | Indazolinhibitorer af wnt-signalvejen og terapeutiske anvendelser deraf |
PL3001903T3 (pl) | 2009-12-21 | 2018-03-30 | Samumed, Llc | 1H-pirazolo[3,4-b]pirydyny i ich zastosowania terapeutyczne |
BR112012023382A2 (pt) * | 2010-03-17 | 2018-05-15 | F Hoffmann La Roche Ag T | compostos, composições e métodos de uso de imidazopiridina. |
MX2013003019A (es) | 2010-09-15 | 2013-05-28 | Hoffmann La Roche | Compuestos de azabenzotiazol, composiciones y metodos de uso. |
CA2817785A1 (en) | 2010-11-19 | 2012-05-24 | Toby Blench | Pyrazolopyridines and pyrazolopyridines and their use as tyk2 inhibitors |
ME03332B (me) | 2011-09-14 | 2019-10-20 | Samumed Llc | Indazol-3-karboksamidi i njihova upotreba kao inhibitora signalnog puta wnt/b-katenina |
PH12017500997A1 (en) | 2012-04-04 | 2018-02-19 | Samumed Llc | Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof |
JP6209593B2 (ja) | 2012-05-04 | 2017-10-04 | サミュメッド リミテッド ライアビリティ カンパニー | 1H−ピラゾロ[3,4−b]ピリジンおよびそれらの治療的使用 |
EP2943198B1 (en) | 2013-01-08 | 2019-07-17 | Samumed, LLC | 3-(benzoimidazol-2-yl)-indazole inhibitors of the wnt signaling pathway and therapeutic uses thereof |
EP2818472A1 (en) * | 2013-06-27 | 2014-12-31 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Imidazo[4,5-c]pyridine and pyrrolo[3,2-c]pyridine compounds as G-protein-coupled receptor kinase 5 (GRK5) modulators |
CN105431433B (zh) * | 2013-07-02 | 2018-04-06 | 先正达参股股份有限公司 | 有杀有害生物活性的具有含硫取代基的二环或三环杂环 |
BR112016000059B1 (pt) * | 2013-07-02 | 2020-12-29 | Syngenta Participations Ag | compostos heterociclos bi ou tricíclicos, composição compreendendo os referidos compostos, método para combater e controlar pragas, método para a proteção de material de propagação vegetal do ataque por pragas e material de propagação vegetal revestido com a referida composição |
US11229208B2 (en) | 2013-07-02 | 2022-01-25 | Syngenta Participations Ag | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents |
JP6653258B2 (ja) | 2014-02-17 | 2020-02-26 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 有害生物防除剤としての2−(ヘタ)アリール置換縮合二環式ヘテロ環誘導体 |
SI3145929T1 (sl) | 2014-05-23 | 2021-10-29 | Hoffmann La Roche | 5-kloro-2-difluorometoksifenil pirazolopirimidinove spojine, ki so zaviralci janusove kinaze |
CN106573891B (zh) | 2014-08-21 | 2020-06-16 | 先正达参股股份有限公司 | 具有含硫取代基的杀有害生物活性杂环衍生物 |
WO2016040182A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof |
WO2016040184A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040180A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040181A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040190A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
WO2016040193A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
WO2016040188A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040185A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof |
WO2016058928A1 (en) * | 2014-10-14 | 2016-04-21 | Syngenta Participations Ag | Pesticidally active heterocyclic derivatives with sulphur containing substituents |
SI3233851T1 (sl) * | 2014-12-17 | 2020-10-30 | Syngenta Participations Ag | Pesticidno aktivni heterociklični derivati s substituenti, ki vsebujejo žveplo |
ES2729984T3 (es) * | 2014-12-31 | 2019-11-07 | Syngenta Participations Ag | Derivados policíclicos activos como plaguicida que contienen sustituyentes de azufre |
UY36547A (es) * | 2015-02-05 | 2016-06-01 | Bayer Cropscience Ag | Derivados heterocíclicos condensados bicíclicos sustituidos por 2-(het)arilo como pesticidas |
US10350199B2 (en) | 2015-08-03 | 2019-07-16 | Samumed, Llc | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof |
US10285983B2 (en) | 2015-08-03 | 2019-05-14 | Samumed, Llc | 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof |
WO2017024003A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc | 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
US10519169B2 (en) | 2015-08-03 | 2019-12-31 | Samumed, Llc | 3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
US10226453B2 (en) | 2015-08-03 | 2019-03-12 | Samumed, Llc | 3-(1H-indol-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
WO2017024010A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof |
WO2017023989A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
WO2017023986A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc | 3-(1h-indol-2-yl)-1h-indazoles and therapeutic uses thereof |
US10206908B2 (en) | 2015-08-03 | 2019-02-19 | Samumed, Llc | 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof |
WO2017023972A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
US10188634B2 (en) | 2015-08-03 | 2019-01-29 | Samumed, Llc | 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
WO2017023975A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[2,3-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof |
US10329309B2 (en) | 2015-08-03 | 2019-06-25 | Samumed, Llc | 3-(3H-imidazo[4,5-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
US10206909B2 (en) | 2015-08-03 | 2019-02-19 | Samumed, Llc | 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
WO2017023980A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof |
US10166218B2 (en) | 2015-08-03 | 2019-01-01 | Samumed, Llc | 3-(1H-indol-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof |
WO2017023987A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof |
US10544139B2 (en) | 2015-11-06 | 2020-01-28 | Samumed, Llc | Treatment of osteoarthritis |
CA3026076A1 (en) | 2016-06-01 | 2017-12-07 | Samumed, Llc | Process for preparing n-(5-(3-(7-(3-fluorophenyl)-3h-imidazo[4,5-c]pyridin-2-yl)-1h-indazol-5-yl)pyridin-3-yl)-3-methylbutanamide |
MX2019004616A (es) | 2016-10-21 | 2019-11-21 | Samumed Llc | Métodos de uso de indazol-3-carboxamidas y su uso como inhibidores de la ruta de señalización de wnt/b-catenina. |
MA46696A (fr) | 2016-11-07 | 2019-09-11 | Samumed Llc | Formulations injectables à dose unique prêtes à l'emploi |
CA3061236A1 (en) | 2017-05-22 | 2018-11-29 | F. Hoffmann-La Roche Ag | Therapeutic compounds and compositions, and methods of use thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA820316A (en) * | 1969-08-12 | Fisons Pest Control Limited | Substituted heterocyclic compounds | |
US3985891A (en) * | 1973-02-03 | 1976-10-12 | Boehringer Ingelheim Gmbh | 2-Phenyl-imidazo (4,5-b)pyridines and salts thereof |
FI58126C (fi) * | 1973-02-03 | 1980-12-10 | Thomae Gmbh Dr K | Foerfarande foer framstaellning av kardiotona och blodtryckssaenkande 2-fenyl-1h-imidatso(4,5-b)pyridiner |
US3891660A (en) * | 1974-02-07 | 1975-06-24 | Squibb & Sons Inc | Derivatives of 1H-imidazo{8 4,5-c{9 pyridine-7-carboxylic acids and esters |
SU566842A1 (ru) * | 1976-01-06 | 1977-07-30 | Донецкое Отделение Физико-Органической Химии Института Физической Химии Им.Л.В.Писаржевского Ан Украинской Сср | Способ получени замещенных имидазопиридинов |
US4281005A (en) * | 1979-03-05 | 1981-07-28 | Merck & Co., Inc. | Novel 2-pyridylimidazole compounds |
DE2927987A1 (de) * | 1979-07-11 | 1981-02-05 | Thomae Gmbh Dr K | Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel |
DE3037464A1 (de) * | 1980-10-03 | 1982-05-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | 6-hydroxy-2-phenyl-imidazo 4,5-b zu pyridine, ihre herstellung und diese sie enthaltende arzneimittel |
EP0072926B1 (de) * | 1981-08-19 | 1986-09-24 | MERCK PATENT GmbH | 2-Aryl-imidazopyridine |
RO86850B (ro) * | 1982-05-03 | 1985-05-31 | Eli Lilly And Company | Procedeu pentru prepararea unor 2-fenilimidazo [4,5 c] piridine |
DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
-
1982
- 1982-11-08 ES ES517193A patent/ES8401486A1/es not_active Expired
- 1982-11-09 FI FI823846A patent/FI79312C/fi not_active IP Right Cessation
- 1982-11-09 IL IL67206A patent/IL67206A0/xx unknown
- 1982-11-09 DD DD82244689A patent/DD205904A5/de not_active IP Right Cessation
- 1982-11-09 NO NO823732A patent/NO158100C/no unknown
- 1982-11-09 AU AU90306/82A patent/AU9030682A/en not_active Abandoned
- 1982-11-09 KR KR8205055A patent/KR890000022B1/ko active
- 1982-11-09 GB GB08231984A patent/GB2113675B/en not_active Expired
- 1982-11-09 PT PT75820A patent/PT75820B/pt unknown
- 1982-11-09 EP EP82110328A patent/EP0079083B1/en not_active Expired - Lifetime
- 1982-11-09 PH PH28109A patent/PH22764A/en unknown
- 1982-11-09 DK DK499582A patent/DK161325C/da not_active IP Right Cessation
- 1982-11-09 IE IE2667/82A patent/IE56478B1/en not_active IP Right Cessation
- 1982-11-09 GR GR69767A patent/GR76746B/el unknown
- 1982-11-09 AR AR82291240A patent/AR241247A1/es active
- 1982-11-09 MC MC821611A patent/MC1491A1/xx unknown
-
1983
- 1983-06-08 ES ES523083A patent/ES8503351A1/es not_active Expired
-
1985
- 1985-01-11 US US06/690,815 patent/US4603139A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PT75820A (en) | 1982-12-01 |
FI823846A0 (fi) | 1982-11-09 |
NO823732L (no) | 1983-05-11 |
NO158100B (no) | 1988-04-05 |
FI79312B (fi) | 1989-08-31 |
PT75820B (en) | 1986-06-11 |
ES517193A0 (es) | 1983-12-01 |
AR241247A1 (es) | 1992-03-31 |
AU9030682A (en) | 1983-05-19 |
KR890000022B1 (ko) | 1989-03-06 |
ES523083A0 (es) | 1985-02-16 |
NO158100C (no) | 1988-07-13 |
EP0079083B1 (en) | 1991-02-27 |
GR76746B (pt) | 1984-08-30 |
DK161325C (da) | 1991-12-02 |
KR840002398A (ko) | 1984-07-02 |
ES8503351A1 (es) | 1985-02-16 |
GB2113675B (en) | 1985-10-30 |
PH22764A (en) | 1988-12-12 |
DD205904A5 (de) | 1984-01-11 |
FI823846L (fi) | 1983-05-11 |
IE56478B1 (en) | 1991-08-14 |
IE822667L (en) | 1983-05-10 |
MC1491A1 (fr) | 1983-09-12 |
DK161325B (da) | 1991-06-24 |
EP0079083A1 (en) | 1983-05-18 |
GB2113675A (en) | 1983-08-10 |
FI79312C (fi) | 1989-12-11 |
ES8401486A1 (es) | 1983-12-01 |
US4603139A (en) | 1986-07-29 |
DK499582A (da) | 1983-05-11 |
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IL63940A0 (en) | Substituted imino-diacids,their preparation and pharmaceutical compositions containing them | |
IL65803A0 (en) | Cyclobutene-dione derivatives,their preparation and pharmaceutical compositions containing them | |
IL64847A0 (en) | Hexapyranose compounds,their manufacture and pharmaceutical compositions containing them | |
IL64777A0 (en) | 3-aminopropoxyaryl derivatives,their preparation and pharmaceutical compositions containing them | |
IL66683A0 (en) | Benzo-heterocycles,their preparation and pharmaceutical compositions containing them | |
IL66408A0 (en) | Amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them | |
IL67180A0 (en) | Morphinate derivatives,their preparation and pharmaceutical compositions containing them | |
IL66449A0 (en) | Bis-amino compounds,their preparation and pharmaceutical compositions containing them | |
IL65327A0 (en) | Acylquinolinone derivatives,their preparation and pharmaceutical compositions containing them | |
IL66424A (en) | 3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them | |
ZA816844B (en) | Substituted iminodiacids,their preparation and pharmaceutical compositions containing them | |
IL66618A0 (en) | Imidazoquinazoline derivatives,their manufacture and pharmaceutical compositions containing them | |
IL65219A0 (en) | Substituted biphenyl compounds,their preparation and pharmaceutical compositions containing them | |
IL66238A0 (en) | Benzothiazolesulfonamide derivatives,their preparation and pharmaceutical compositions containing them | |
IL65422A (en) | 2-piperazino-pyrimidine derivatives,their preparation and pharmaceutical compositions containing them | |
IL67284A (en) | N-substituted-2-pyridylindoles,their manufacture and pharmaceutical compositions containing them | |
IL75720A0 (en) | Morpholinol compounds,their preparation and pharmaceutical compositions containing them | |
IL64489A0 (en) | Benzodiazepine compounds,their preparation and pharmaceutical compositions containing them |