IL64759A - 3-substituted 1,3-dihydro-7-hydroxy-6-methyl-furo-(3,4-c)-pyridine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3-substituted 1,3-dihydro-7-hydroxy-6-methyl-furo-(3,4-c)-pyridine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL64759A
IL64759A IL64759A IL6475982A IL64759A IL 64759 A IL64759 A IL 64759A IL 64759 A IL64759 A IL 64759A IL 6475982 A IL6475982 A IL 6475982A IL 64759 A IL64759 A IL 64759A
Authority
IL
Israel
Prior art keywords
furo
dihydro
hydroxy
substituted
methyl
Prior art date
Application number
IL64759A
Other languages
English (en)
Other versions
IL64759A0 (en
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of IL64759A0 publication Critical patent/IL64759A0/xx
Publication of IL64759A publication Critical patent/IL64759A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
IL64759A 1981-02-10 1982-01-11 3-substituted 1,3-dihydro-7-hydroxy-6-methyl-furo-(3,4-c)-pyridine derivatives,their preparation and pharmaceutical compositions containing them IL64759A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8104072 1981-02-10

Publications (2)

Publication Number Publication Date
IL64759A0 IL64759A0 (en) 1982-03-31
IL64759A true IL64759A (en) 1985-09-29

Family

ID=10519587

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64759A IL64759A (en) 1981-02-10 1982-01-11 3-substituted 1,3-dihydro-7-hydroxy-6-methyl-furo-(3,4-c)-pyridine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (34)

Country Link
US (1) US4383998A (zh)
JP (1) JPS57150688A (zh)
KR (1) KR870000206B1 (zh)
AR (1) AR230284A1 (zh)
AU (1) AU545876B2 (zh)
BE (1) BE891797A (zh)
CA (1) CA1175837A (zh)
CH (1) CH649554A5 (zh)
DE (1) DE3204596A1 (zh)
DK (1) DK157551C (zh)
DZ (1) DZ376A1 (zh)
ES (1) ES8302714A1 (zh)
FI (1) FI75347C (zh)
FR (2) FR2499574A1 (zh)
GB (1) GB2092586B (zh)
GR (1) GR75905B (zh)
HK (1) HK22485A (zh)
HU (1) HU185088B (zh)
IE (1) IE52376B1 (zh)
IL (1) IL64759A (zh)
IN (1) IN156817B (zh)
IT (1) IT1157252B (zh)
LU (1) LU83886A1 (zh)
MA (1) MA19378A1 (zh)
MX (1) MX6983E (zh)
NL (1) NL186697C (zh)
NO (1) NO156373C (zh)
NZ (1) NZ199528A (zh)
OA (1) OA07003A (zh)
PT (1) PT74408B (zh)
SE (1) SE456994B (zh)
SG (1) SG85384G (zh)
YU (1) YU44000B (zh)
ZA (1) ZA82158B (zh)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735950A (en) * 1983-04-05 1988-04-05 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same
IN160104B (zh) * 1983-04-05 1987-06-27 Scras
GB8327817D0 (en) * 1983-10-18 1983-11-16 Scras 4-halo-furo-(3 4-c)-pyridine derivatives
GB8330517D0 (en) * 1983-11-16 1983-12-21 Scras 6-vinyl-furo-(3,4-c)pyridine derivatives
GB8330658D0 (en) * 1983-11-17 1983-12-29 Scras 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives
GB8402740D0 (en) * 1984-02-02 1984-03-07 Scras Furo-(3 4-c)-pyridine derivatives
GB8414559D0 (en) * 1984-06-07 1984-07-11 Scras Pyridine derivatives
GB8422379D0 (en) * 1984-09-05 1984-10-10 Scras Derivatives
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
DE3519693A1 (de) * 1985-06-01 1987-01-02 Basf Ag Pyridin-derivate, ihre herstellung und verwendung
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
DE3990349T1 (de) * 1988-04-06 1990-04-26 Scras Stereospezifisches verfahren zur herstellung von enantiomeren von furo(3,4-c)pyridin, so erhaltene verbindungen und therapeutische zusammensetzungen auf basis dieser verbindungen
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives
GB8917168D0 (en) * 1989-07-27 1989-09-13 Scras Asymmetric synthesis of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
GB0221494D0 (en) * 2002-09-16 2002-10-23 Generics Uk Ltd Novel processes for the preparation of 1.3-dihydro-6-methylfuro (3,4-c) pyndin derivatives
HUP0300990A2 (hu) * 2003-04-15 2005-05-30 SynoSens Kutató és Fejlesztő Kft. Szinergista gyógyszer-kombináció a diabetesz megelőzésére vagy kezelésére
US20060089374A1 (en) * 2003-07-17 2006-04-27 Glenn Cornett Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease
CA2532807A1 (en) * 2003-07-17 2005-02-03 Cotherix, Inc. Combination therapies for treatment of hypertension and complications in patients with diabetes or metabolic syndrome
CA2581337A1 (en) * 2004-09-22 2006-03-30 Glenn Cornett Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease
US20060153934A1 (en) * 2005-01-13 2006-07-13 Navitas Pharma Combination therapies of cicletanine and magnesium
US20060154959A1 (en) * 2005-01-13 2006-07-13 Navitas Pharma Combination therapies of cicletanine and carvedilol
US20070141174A1 (en) * 2005-01-13 2007-06-21 Navitas Pharma, Inc. Enantiomeric compositions of cicletanine, in combination with other agents, for the treatment of hypertension
US20080096915A1 (en) * 2005-01-13 2008-04-24 Greenberg Traurig LLP Compositions for the treatment of metabolic disorders
US20070105817A1 (en) * 2005-11-09 2007-05-10 Jim Page Use of cicletanine and other furopyridines for treatment of systolic-predominant hypertension, isolated systolic hypertension, elevated pulse pressure, and general hypertension
US20080312241A1 (en) * 2007-01-03 2008-12-18 Gilead Sciences, Inc. Cicletanine and PKC inhibitors in the treatment of pulmonary and cardiac disorders
AR073259A1 (es) * 2008-07-29 2010-10-28 Merck & Co Inc Derivados de furosemida utiles como diureticos
US8214941B2 (en) 2008-10-02 2012-07-10 Kohler Co. Slip-fit clamping system for mounting a fitting on a wall
US8377911B2 (en) * 2009-10-09 2013-02-19 Merck Sharp & Dohme Corp. Diuretics
WO2011053519A1 (en) * 2009-10-29 2011-05-05 Merck Sharp & Dohme Corp. Diuretics
WO2015103445A1 (en) * 2013-12-31 2015-07-09 Rockey Don C Systems, methods, techniques, and compounds in research and treatment of portal hypertension and other conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use

Also Published As

Publication number Publication date
FI75347B (fi) 1988-02-29
NO156373C (no) 1987-09-09
GB2092586B (en) 1984-09-26
FR2499574B1 (zh) 1984-03-30
PT74408B (en) 1983-07-07
HK22485A (en) 1985-03-29
IT8219502A0 (it) 1982-02-08
DK157551B (da) 1990-01-22
DE3204596C2 (zh) 1991-07-04
SE456994B (sv) 1988-11-21
DK54382A (da) 1982-08-11
FI820353L (fi) 1982-08-11
NL186697C (nl) 1991-02-01
DZ376A1 (fr) 2004-09-13
GR75905B (zh) 1984-08-02
IN156817B (zh) 1985-11-09
AR230284A1 (es) 1984-03-01
FR2499406A1 (fr) 1982-08-13
JPH0261477B2 (zh) 1990-12-20
IE52376B1 (en) 1987-09-30
NL186697B (nl) 1990-09-03
US4383998A (en) 1983-05-17
ZA82158B (en) 1982-11-24
MA19378A1 (fr) 1982-10-01
BE891797A (fr) 1982-04-30
KR830009106A (ko) 1983-12-17
DE3204596A1 (de) 1982-09-09
CA1175837A (en) 1984-10-09
GB2092586A (en) 1982-08-18
PT74408A (en) 1982-03-01
JPS57150688A (en) 1982-09-17
NZ199528A (en) 1984-02-03
ES509449A0 (es) 1983-01-16
YU44000B (en) 1990-02-28
IE820288L (en) 1982-08-10
MX6983E (es) 1987-01-19
OA07003A (fr) 1983-08-31
YU25382A (en) 1984-08-31
FI75347C (fi) 1988-06-09
KR870000206B1 (ko) 1987-02-16
SE8200744L (sv) 1982-08-11
NO820253L (no) 1982-08-11
IL64759A0 (en) 1982-03-31
CH649554A5 (fr) 1985-05-31
SG85384G (en) 1985-06-07
NL8200180A (nl) 1982-09-01
NO156373B (no) 1987-06-01
AU545876B2 (en) 1985-08-01
IT1157252B (it) 1987-02-11
FR2499406B1 (zh) 1984-03-30
DK157551C (da) 1990-06-11
FR2499574A1 (fr) 1982-08-13
HU185088B (en) 1984-11-28
AU8029482A (en) 1982-08-19
LU83886A1 (fr) 1982-06-30
ES8302714A1 (es) 1983-01-16

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