IL62189A - Acyl-derivatives of carnitine - Google Patents

Acyl-derivatives of carnitine

Info

Publication number
IL62189A
IL62189A IL62189A IL6218981A IL62189A IL 62189 A IL62189 A IL 62189A IL 62189 A IL62189 A IL 62189A IL 6218981 A IL6218981 A IL 6218981A IL 62189 A IL62189 A IL 62189A
Authority
IL
Israel
Prior art keywords
carnitine
acyl
derivatives
Prior art date
Application number
IL62189A
Other languages
English (en)
Other versions
IL62189A0 (en
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of IL62189A0 publication Critical patent/IL62189A0/xx
Publication of IL62189A publication Critical patent/IL62189A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL62189A 1980-03-06 1981-02-23 Acyl-derivatives of carnitine IL62189A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48099/80A IT1145362B (it) 1980-03-06 1980-03-06 Classe di acil-derivati della carnitina procedimento per la loro preparazione e loro uso terapeutico

Publications (2)

Publication Number Publication Date
IL62189A0 IL62189A0 (en) 1981-03-31
IL62189A true IL62189A (en) 1985-10-31

Family

ID=11264505

Family Applications (1)

Application Number Title Priority Date Filing Date
IL62189A IL62189A (en) 1980-03-06 1981-02-23 Acyl-derivatives of carnitine

Country Status (22)

Country Link
US (2) US4766222A (el)
JP (1) JPS56139442A (el)
AR (1) AR228591A1 (el)
AT (1) AT376200B (el)
AU (1) AU543799B2 (el)
BE (1) BE887695A (el)
CA (1) CA1178971A (el)
CH (1) CH653008A5 (el)
DE (1) DE3107743A1 (el)
DK (1) DK154424C (el)
ES (1) ES8201535A1 (el)
FI (1) FI78680C (el)
FR (1) FR2477536B1 (el)
GB (1) GB2071091B (el)
GR (1) GR74440B (el)
IE (1) IE50959B1 (el)
IL (1) IL62189A (el)
IT (1) IT1145362B (el)
LU (1) LU83183A1 (el)
MX (1) MX155928A (el)
NL (1) NL8101067A (el)
SE (1) SE452004B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1145371B (it) * 1980-05-30 1986-11-05 Sigma Tau Ind Farmaceuti Alcossi-acil carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
IT1147079B (it) * 1980-05-30 1986-11-19 Sigma Tau Ind Farmacuetiche Ri Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono
IT1238344B (it) * 1989-10-20 1993-07-13 Sigma Tau Ind Farmaceuti Estere della l-carnitina con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che lo contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma
IT1240775B (it) * 1990-02-23 1993-12-17 Sigma Tau Ind Farmaceuti Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma.
US6323237B1 (en) * 1997-03-17 2001-11-27 Btg International Limited Therapeutic compositions
AU7828200A (en) 1999-09-23 2001-04-24 Juvenon Corporation Nutritional supplement for increased energy and stamina
US6562869B1 (en) 1999-09-23 2003-05-13 Juvenon, Inc. Nutritional supplement for increased energy and stamina
WO2001032168A1 (en) 1999-11-03 2001-05-10 Juvenon, Inc. Method of treating benign forgetfulness
WO2005094897A2 (en) * 2004-04-01 2005-10-13 Cardiome Pharma Corp. Pegylated ion channel modulating compounds
JP6296433B2 (ja) * 2012-11-22 2018-03-20 国立大学法人山形大学 生体適合性ポリマー及びその製造方法並びにそれを製造するための新規化合物
WO2018226854A2 (en) * 2017-06-06 2018-12-13 Wayne State University Antifouling polymer coatings and reverse coating method

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1108125A (fr) * 1953-05-08 1956-01-09 Laboratoires Labaz Soc D Procédé de préparation d'un dérivé stable de la carnitine
US3624887A (en) * 1970-03-02 1971-12-07 Bunker Ramo Pin and socket removal tool
AU518617B2 (en) * 1977-04-29 1981-10-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Therapeutic application of acetyl-d, 1-carnitine
JPS5481963A (en) * 1977-12-13 1979-06-29 Ihachi Nosaka Roll paper holder for lavatory
DE2903579A1 (de) * 1978-02-03 1979-08-09 Sigma Tau Ind Farmaceuti Verwendung von acetylcarnitin und anderen acylderivaten des carnitins zur behandlung der hyperlipoproteinaemie und hyperlimpidaemie sowie arzneimittel
IT1156741B (it) * 1978-05-15 1987-02-04 Sigma Tau Ind Farmaceuti Applicazione terapeutica della carnitina e di alcuni derivati acilati della carnitina nell'emodialisi
IT1156769B (it) * 1978-05-25 1987-02-04 Sigma Tau Ind Farmaceuti Applicazione terapeutica della carnitina e di altri acil derivati della carnitina
IT1156840B (it) * 1978-06-27 1987-02-04 Sigma Tau Ind Farmaceuti Acil derivati della carnitina
JPS5554821A (en) * 1978-10-18 1980-04-22 Iseki Agricult Mach Discharging dust adjuster of thresher
US4518776A (en) * 1982-07-19 1985-05-21 Ciba Geigy Corporation Process for producing sulfonylureas
DE3427847A1 (de) * 1983-12-09 1985-06-13 Bayer Ag, 5090 Leverkusen Thiolan-2,4-dion-3-carboxamide
US4707491A (en) * 1985-12-20 1987-11-17 Washington University Anticonvulsant γ-thiobutyrolactone derivatives

Also Published As

Publication number Publication date
CH653008A5 (it) 1985-12-13
ATA103981A (de) 1984-03-15
MX155928A (es) 1988-05-24
SE8101267L (sv) 1981-09-07
DK154424C (da) 1989-05-22
GB2071091A (en) 1981-09-16
IT1145362B (it) 1986-11-05
DK100181A (da) 1981-09-07
IT8048099A0 (it) 1980-03-06
BE887695A (fr) 1981-06-15
DK154424B (da) 1988-11-14
GB2071091B (en) 1984-09-12
AU6802881A (en) 1981-09-24
FI810695L (fi) 1981-09-07
FI78680C (fi) 1989-09-11
CA1178971A (en) 1984-12-04
US4859698A (en) 1989-08-22
DE3107743A1 (de) 1981-12-03
ES500131A0 (es) 1982-01-01
IL62189A0 (en) 1981-03-31
US4766222A (en) 1988-08-23
JPS56139442A (en) 1981-10-30
NL8101067A (nl) 1981-10-01
IE50959B1 (en) 1986-08-20
IE810359L (en) 1981-09-06
FR2477536A1 (fr) 1981-09-11
FI78680B (fi) 1989-05-31
FR2477536B1 (fr) 1986-04-04
LU83183A1 (fr) 1981-06-24
SE452004B (sv) 1987-11-09
ES8201535A1 (es) 1982-01-01
GR74440B (el) 1984-06-28
AU543799B2 (en) 1985-05-02
AT376200B (de) 1984-10-25
AR228591A1 (es) 1983-03-30

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Legal Events

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KB Patent renewed
EXP Patent expired