AT376200B - Verfahren zur herstellung neuer acylderivaten des carnitins - Google Patents
Verfahren zur herstellung neuer acylderivaten des carnitinsInfo
- Publication number
- AT376200B AT376200B AT0103981A AT103981A AT376200B AT 376200 B AT376200 B AT 376200B AT 0103981 A AT0103981 A AT 0103981A AT 103981 A AT103981 A AT 103981A AT 376200 B AT376200 B AT 376200B
- Authority
- AT
- Austria
- Prior art keywords
- carnitin
- acyl derivatives
- producing new
- new acyl
- producing
- Prior art date
Links
- PHIQHXFUZVPYII-LURJTMIESA-O (S)-carnitinium Chemical class C[N+](C)(C)C[C@@H](O)CC(O)=O PHIQHXFUZVPYII-LURJTMIESA-O 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48099/80A IT1145362B (it) | 1980-03-06 | 1980-03-06 | Classe di acil-derivati della carnitina procedimento per la loro preparazione e loro uso terapeutico |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA103981A ATA103981A (de) | 1984-03-15 |
| AT376200B true AT376200B (de) | 1984-10-25 |
Family
ID=11264505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0103981A AT376200B (de) | 1980-03-06 | 1981-03-06 | Verfahren zur herstellung neuer acylderivaten des carnitins |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US4766222A (de) |
| JP (1) | JPS56139442A (de) |
| AR (1) | AR228591A1 (de) |
| AT (1) | AT376200B (de) |
| AU (1) | AU543799B2 (de) |
| BE (1) | BE887695A (de) |
| CA (1) | CA1178971A (de) |
| CH (1) | CH653008A5 (de) |
| DE (1) | DE3107743A1 (de) |
| DK (1) | DK154424C (de) |
| ES (1) | ES8201535A1 (de) |
| FI (1) | FI78680C (de) |
| FR (1) | FR2477536B1 (de) |
| GB (1) | GB2071091B (de) |
| GR (1) | GR74440B (de) |
| IE (1) | IE50959B1 (de) |
| IL (1) | IL62189A (de) |
| IT (1) | IT1145362B (de) |
| LU (1) | LU83183A1 (de) |
| MX (1) | MX155928A (de) |
| NL (1) | NL8101067A (de) |
| SE (1) | SE452004B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1145371B (it) * | 1980-05-30 | 1986-11-05 | Sigma Tau Ind Farmaceuti | Alcossi-acil carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono |
| IT1147079B (it) * | 1980-05-30 | 1986-11-19 | Sigma Tau Ind Farmacuetiche Ri | Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono |
| IT1238344B (it) * | 1989-10-20 | 1993-07-13 | Sigma Tau Ind Farmaceuti | Estere della l-carnitina con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che lo contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma |
| IT1240775B (it) * | 1990-02-23 | 1993-12-17 | Sigma Tau Ind Farmaceuti | Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma. |
| US6323237B1 (en) * | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
| AU7828200A (en) | 1999-09-23 | 2001-04-24 | Juvenon Corporation | Nutritional supplement for increased energy and stamina |
| US6562869B1 (en) | 1999-09-23 | 2003-05-13 | Juvenon, Inc. | Nutritional supplement for increased energy and stamina |
| WO2001032168A1 (en) | 1999-11-03 | 2001-05-10 | Juvenon, Inc. | Method of treating benign forgetfulness |
| WO2005094897A2 (en) * | 2004-04-01 | 2005-10-13 | Cardiome Pharma Corp. | Pegylated ion channel modulating compounds |
| JP6296433B2 (ja) * | 2012-11-22 | 2018-03-20 | 国立大学法人山形大学 | 生体適合性ポリマー及びその製造方法並びにそれを製造するための新規化合物 |
| WO2018226854A2 (en) * | 2017-06-06 | 2018-12-13 | Wayne State University | Antifouling polymer coatings and reverse coating method |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1108125A (fr) * | 1953-05-08 | 1956-01-09 | Laboratoires Labaz Soc D | Procédé de préparation d'un dérivé stable de la carnitine |
| US3624887A (en) * | 1970-03-02 | 1971-12-07 | Bunker Ramo | Pin and socket removal tool |
| AU518617B2 (en) * | 1977-04-29 | 1981-10-08 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutic application of acetyl-d, 1-carnitine |
| JPS5481963A (en) * | 1977-12-13 | 1979-06-29 | Ihachi Nosaka | Roll paper holder for lavatory |
| DE2903579A1 (de) * | 1978-02-03 | 1979-08-09 | Sigma Tau Ind Farmaceuti | Verwendung von acetylcarnitin und anderen acylderivaten des carnitins zur behandlung der hyperlipoproteinaemie und hyperlimpidaemie sowie arzneimittel |
| IT1156741B (it) * | 1978-05-15 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Applicazione terapeutica della carnitina e di alcuni derivati acilati della carnitina nell'emodialisi |
| IT1156769B (it) * | 1978-05-25 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Applicazione terapeutica della carnitina e di altri acil derivati della carnitina |
| IT1156840B (it) * | 1978-06-27 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Acil derivati della carnitina |
| JPS5554821A (en) * | 1978-10-18 | 1980-04-22 | Iseki Agricult Mach | Discharging dust adjuster of thresher |
| US4518776A (en) * | 1982-07-19 | 1985-05-21 | Ciba Geigy Corporation | Process for producing sulfonylureas |
| DE3427847A1 (de) * | 1983-12-09 | 1985-06-13 | Bayer Ag, 5090 Leverkusen | Thiolan-2,4-dion-3-carboxamide |
| US4707491A (en) * | 1985-12-20 | 1987-11-17 | Washington University | Anticonvulsant γ-thiobutyrolactone derivatives |
-
1980
- 1980-03-06 IT IT48099/80A patent/IT1145362B/it active
-
1981
- 1981-02-23 IL IL62189A patent/IL62189A/xx not_active IP Right Cessation
- 1981-02-23 IE IE359/81A patent/IE50959B1/en not_active IP Right Cessation
- 1981-02-26 BE BE0/203935A patent/BE887695A/fr not_active IP Right Cessation
- 1981-02-26 SE SE8101267A patent/SE452004B/sv not_active IP Right Cessation
- 1981-02-28 DE DE19813107743 patent/DE3107743A1/de not_active Ceased
- 1981-03-03 AU AU68028/81A patent/AU543799B2/en not_active Expired
- 1981-03-03 LU LU83183A patent/LU83183A1/fr unknown
- 1981-03-04 FR FR8104331A patent/FR2477536B1/fr not_active Expired
- 1981-03-04 GR GR64312A patent/GR74440B/el unknown
- 1981-03-04 GB GB8106836A patent/GB2071091B/en not_active Expired
- 1981-03-05 CH CH1485/81A patent/CH653008A5/it not_active IP Right Cessation
- 1981-03-05 NL NL8101067A patent/NL8101067A/nl not_active Application Discontinuation
- 1981-03-05 ES ES500131A patent/ES8201535A1/es not_active Expired
- 1981-03-05 CA CA000372368A patent/CA1178971A/en not_active Expired
- 1981-03-05 MX MX186251A patent/MX155928A/es unknown
- 1981-03-05 DK DK100181A patent/DK154424C/da not_active IP Right Cessation
- 1981-03-05 FI FI810695A patent/FI78680C/fi not_active IP Right Cessation
- 1981-03-06 AR AR284535A patent/AR228591A1/es active
- 1981-03-06 AT AT0103981A patent/AT376200B/de not_active IP Right Cessation
- 1981-03-06 JP JP3305481A patent/JPS56139442A/ja active Pending
-
1987
- 1987-06-30 US US07/068,748 patent/US4766222A/en not_active Expired - Lifetime
-
1988
- 1988-05-31 US US07/200,641 patent/US4859698A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CH653008A5 (it) | 1985-12-13 |
| ATA103981A (de) | 1984-03-15 |
| MX155928A (es) | 1988-05-24 |
| SE8101267L (sv) | 1981-09-07 |
| IL62189A (en) | 1985-10-31 |
| DK154424C (da) | 1989-05-22 |
| GB2071091A (en) | 1981-09-16 |
| IT1145362B (it) | 1986-11-05 |
| DK100181A (da) | 1981-09-07 |
| IT8048099A0 (it) | 1980-03-06 |
| BE887695A (fr) | 1981-06-15 |
| DK154424B (da) | 1988-11-14 |
| GB2071091B (en) | 1984-09-12 |
| AU6802881A (en) | 1981-09-24 |
| FI810695L (fi) | 1981-09-07 |
| FI78680C (fi) | 1989-09-11 |
| CA1178971A (en) | 1984-12-04 |
| US4859698A (en) | 1989-08-22 |
| DE3107743A1 (de) | 1981-12-03 |
| ES500131A0 (es) | 1982-01-01 |
| IL62189A0 (en) | 1981-03-31 |
| US4766222A (en) | 1988-08-23 |
| JPS56139442A (en) | 1981-10-30 |
| NL8101067A (nl) | 1981-10-01 |
| IE50959B1 (en) | 1986-08-20 |
| IE810359L (en) | 1981-09-06 |
| FR2477536A1 (fr) | 1981-09-11 |
| FI78680B (fi) | 1989-05-31 |
| FR2477536B1 (fr) | 1986-04-04 |
| LU83183A1 (fr) | 1981-06-24 |
| SE452004B (sv) | 1987-11-09 |
| ES8201535A1 (es) | 1982-01-01 |
| GR74440B (de) | 1984-06-28 |
| AU543799B2 (en) | 1985-05-02 |
| AR228591A1 (es) | 1983-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee | ||
| ELA | Expired due to lapse of time |