IL61775A - 7-(cyclised guanidine)cephalosporin derivatives having antibacterial activity,their preparation and pharmaceutical compositions comprising them - Google Patents

7-(cyclised guanidine)cephalosporin derivatives having antibacterial activity,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL61775A
IL61775A IL61775A IL6177580A IL61775A IL 61775 A IL61775 A IL 61775A IL 61775 A IL61775 A IL 61775A IL 6177580 A IL6177580 A IL 6177580A IL 61775 A IL61775 A IL 61775A
Authority
IL
Israel
Prior art keywords
6alkyl
hydroxy
aromatic
carboxy
cyano
Prior art date
Application number
IL61775A
Other languages
English (en)
Other versions
IL61775A0 (en
Original Assignee
Ici Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Pharma filed Critical Ici Pharma
Publication of IL61775A0 publication Critical patent/IL61775A0/xx
Publication of IL61775A publication Critical patent/IL61775A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68Halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Laminated Bodies (AREA)
  • Table Devices Or Equipment (AREA)
IL61775A 1979-12-24 1980-12-21 7-(cyclised guanidine)cephalosporin derivatives having antibacterial activity,their preparation and pharmaceutical compositions comprising them IL61775A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7931616A FR2472574A1 (fr) 1979-12-24 1979-12-24 Derives de cephalosporine et composition pharmaceutique les contenant

Publications (2)

Publication Number Publication Date
IL61775A0 IL61775A0 (en) 1981-01-30
IL61775A true IL61775A (en) 1984-08-31

Family

ID=9233132

Family Applications (1)

Application Number Title Priority Date Filing Date
IL61775A IL61775A (en) 1979-12-24 1980-12-21 7-(cyclised guanidine)cephalosporin derivatives having antibacterial activity,their preparation and pharmaceutical compositions comprising them

Country Status (27)

Country Link
US (1) US4463173A (xx)
EP (1) EP0031708B1 (xx)
JP (1) JPS56158787A (xx)
AT (1) ATE7918T1 (xx)
AU (1) AU544374B2 (xx)
CA (1) CA1175805A (xx)
CS (1) CS226025B2 (xx)
DD (1) DD155520A5 (xx)
DE (1) DE3068273D1 (xx)
DK (1) DK552480A (xx)
ES (2) ES8201167A1 (xx)
FI (1) FI803817L (xx)
FR (1) FR2472574A1 (xx)
GR (1) GR71920B (xx)
HU (1) HU186289B (xx)
IL (1) IL61775A (xx)
MW (1) MW5380A1 (xx)
NO (1) NO803903L (xx)
NZ (1) NZ195731A (xx)
PH (1) PH21662A (xx)
PL (2) PL132587B1 (xx)
PT (1) PT72265B (xx)
SU (2) SU1031408A3 (xx)
YU (2) YU324680A (xx)
ZA (1) ZA807710B (xx)
ZM (1) ZM11380A1 (xx)
ZW (1) ZW31280A1 (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2496666A1 (fr) * 1980-12-22 1982-06-25 Ici Pharma Nouveaux derives de cephalosporine et composition pharmaceutique les contenant
FR2496665A1 (fr) * 1980-12-23 1982-06-25 Ici Pharma Nouveaux derives de penicilline et composition pharmaceutique les contenant
ZA824094B (en) * 1981-06-19 1983-07-27 Ici Plc A process for the manufacture of cephalosporin derivative
EP0071370A3 (en) * 1981-07-23 1984-05-16 Ici Pharma Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
US4504478A (en) * 1981-09-18 1985-03-12 Imperial Chemical Industries Plc Cephalosporin-1-oxide derivatives
EP0082648A3 (en) * 1981-12-21 1984-09-26 Imperial Chemical Industries Plc Cephalosporin derivatives
JPS59110695A (ja) * 1982-12-16 1984-06-26 Asahi Chem Ind Co Ltd 経口用セフアロスポリン
GR78718B (xx) * 1983-01-31 1984-09-27 Ici Pharma
US4855420A (en) * 1983-06-03 1989-08-08 Ici Pharma Cephalosporin derivatives
GB8316589D0 (en) * 1983-06-17 1983-07-20 Ici Plc Crystalline salts
US4547573A (en) * 1983-12-02 1985-10-15 Ici Pharma Process for preparing cephalosporin derivatives
EP0215435B1 (en) * 1985-09-09 1993-03-03 Otsuka Pharmaceutical Co., Ltd. 2-oxa-isocephem compounds, compositions containing same and processes for preparing same
US4760140A (en) * 1986-10-20 1988-07-26 American Cyanamid Company 3-substituted-7-[5-substituted-2-thiazolyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, diphenylmethyl esters
US6476220B2 (en) * 2000-11-27 2002-11-05 Aurobindo Pharma Limited Process for the preparation of furaca
US20030135041A1 (en) 2002-01-04 2003-07-17 Orchid Chemicals & Pharmaceuticals Limited, India Synthesis of ceftiofur intermediate
MX2011003239A (es) * 2008-09-26 2011-04-28 Merck Sharp & Dohme Nuevos derivados de bencimidazol ciclicos utiles como agentes anti-diabeticos.
WO2015042438A1 (en) * 2013-09-19 2015-03-26 The Florida International Board Of Trustees Modesto A. Maidique Campus Selective inhibition of bacterial topoisomerase i

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2430375A1 (de) * 1973-06-26 1975-03-20 Leo Pharm Prod Ltd 7-amino-delta hoch 3 -cephem-4-carbonsaeure-derivate
US4255424A (en) * 1979-04-27 1981-03-10 Merck & Co., Inc. 7-N-Heterocyclyl 1-oxa, 1-aza, and 1-carbadethiacephalosporins
EP0018595B1 (en) * 1979-04-27 1986-08-20 Merck & Co. Inc. 7-n-heterocyclyl cephalosporins, a process for preparing and a pharmaceutical composition comprising the same
US4358447A (en) * 1979-04-27 1982-11-09 Merck & Co., Inc. 7-N-Heterocyclyl cephalosporins
US4282219A (en) * 1979-08-01 1981-08-04 Merck & Co., Inc. 7-N-Heterocyclyl cephalosporins and antibiotic pharmaceutical compositions containing them

Also Published As

Publication number Publication date
PL228757A1 (xx) 1982-01-04
GR71920B (xx) 1983-08-17
PT72265A (en) 1981-01-01
EP0031708B1 (en) 1984-06-13
US4463173A (en) 1984-07-31
ZA807710B (en) 1981-11-25
ES498157A0 (es) 1981-12-01
IL61775A0 (en) 1981-01-30
JPH0320398B2 (xx) 1991-03-19
YU292682A (en) 1983-06-30
YU324680A (en) 1983-04-30
PT72265B (en) 1981-11-05
PL132587B1 (en) 1985-03-30
PL133508B1 (en) 1985-06-29
ES8204438A1 (es) 1982-05-01
DE3068273D1 (en) 1984-07-19
ES502352A0 (es) 1982-05-01
ES8201167A1 (es) 1981-12-01
NO803903L (no) 1981-06-25
CA1175805A (en) 1984-10-09
AU544374B2 (en) 1985-05-23
FR2472574A1 (fr) 1981-07-03
ZM11380A1 (en) 1982-10-21
ZW31280A1 (en) 1981-09-29
DK552480A (da) 1981-06-25
ATE7918T1 (de) 1984-06-15
NZ195731A (en) 1984-04-27
SU1077573A3 (ru) 1984-02-29
HU186289B (en) 1985-07-29
PL232847A1 (xx) 1982-03-29
JPS56158787A (en) 1981-12-07
MW5380A1 (en) 1982-09-08
SU1031408A3 (ru) 1983-07-23
AU6513480A (en) 1981-07-02
DD155520A5 (de) 1982-06-16
EP0031708A2 (en) 1981-07-08
PH21662A (en) 1988-01-13
FI803817L (fi) 1981-06-25
EP0031708A3 (en) 1982-02-24
CS226025B2 (en) 1984-03-19

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