IL60326A - Pharmaceutical compositions for parenteral administration of fat-soluble active substances - Google Patents

Pharmaceutical compositions for parenteral administration of fat-soluble active substances

Info

Publication number
IL60326A
IL60326A IL60326A IL6032680A IL60326A IL 60326 A IL60326 A IL 60326A IL 60326 A IL60326 A IL 60326A IL 6032680 A IL6032680 A IL 6032680A IL 60326 A IL60326 A IL 60326A
Authority
IL
Israel
Prior art keywords
fat
pharmaceutical compositions
parenteral administration
active substances
soluble active
Prior art date
Application number
IL60326A
Other languages
English (en)
Other versions
IL60326A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL60326A0 publication Critical patent/IL60326A0/xx
Publication of IL60326A publication Critical patent/IL60326A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL60326A 1979-06-22 1980-06-16 Pharmaceutical compositions for parenteral administration of fat-soluble active substances IL60326A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH586379 1979-06-22

Publications (2)

Publication Number Publication Date
IL60326A0 IL60326A0 (en) 1980-09-16
IL60326A true IL60326A (en) 1983-09-30

Family

ID=4300559

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60326A IL60326A (en) 1979-06-22 1980-06-16 Pharmaceutical compositions for parenteral administration of fat-soluble active substances

Country Status (21)

Country Link
US (1) US4411894A (fr)
EP (1) EP0021337B1 (fr)
JP (1) JPS567714A (fr)
KR (1) KR850001301B1 (fr)
AR (1) AR230178A1 (fr)
AT (1) ATE5508T1 (fr)
AU (1) AU534959B2 (fr)
CA (1) CA1173360A (fr)
DE (1) DE3065818D1 (fr)
DK (1) DK155172C (fr)
ES (1) ES492676A0 (fr)
FI (1) FI72875C (fr)
HU (1) HU186296B (fr)
IE (1) IE49615B1 (fr)
IL (1) IL60326A (fr)
MC (1) MC1336A1 (fr)
NO (1) NO155226C (fr)
NZ (1) NZ194047A (fr)
PH (1) PH16795A (fr)
PT (1) PT71436B (fr)
ZA (1) ZA803567B (fr)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
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JPS59152348A (ja) * 1983-02-19 1984-08-31 Kaken Pharmaceut Co Ltd ビフエニリルプロピオン酸エステル誘導体およびその製造法
JPH0768117B2 (ja) * 1983-05-06 1995-07-26 ベスター・インコーポレイテツド 薬剤放出調整用小胞製剤
US5186941A (en) * 1983-05-06 1993-02-16 Vestar, Inc. Vesicle formulation for the controlled release of therapeutic agents
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
CA1237670A (fr) * 1983-05-26 1988-06-07 Andrew S. Janoff Reduction de la toxicite de certains medicaments
JPS601122A (ja) * 1983-06-20 1985-01-07 Green Cross Corp:The ビフエニリルプロピオン酸誘導体脂肪乳剤
CA1264162A (fr) * 1984-03-15 1990-01-02 Manfred Breuninger Glycero-oxy-phosphatides
JPS60208910A (ja) * 1984-03-31 1985-10-21 Green Cross Corp:The 水難溶性薬物・リン脂質複合体の製造方法
US4891208A (en) * 1985-04-10 1990-01-02 The Liposome Company, Inc. Steroidal liposomes
US5231112A (en) 1984-04-12 1993-07-27 The Liposome Company, Inc. Compositions containing tris salt of cholesterol hemisuccinate and antifungal
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
CA1264668C (fr) * 1984-06-20 1990-01-23 Techniques d'extrusion pour la production de liposomes
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
CA1270198A (fr) * 1984-08-08 1990-06-12 Marcel B. Bally Encapsulation d'agents antineoplastiques dans des liposones
US5077056A (en) * 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
JPS61100518A (ja) * 1984-10-22 1986-05-19 Ono Pharmaceut Co Ltd ジミリストイルホスフアチジルコリンを主成分とする凍結乾燥されたリポゾ−ム製剤
AU587600B2 (en) * 1985-01-11 1989-08-24 Regents Of The University Of California, The Method for preserving liposomes
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
CA1256372A (fr) * 1985-04-11 1989-06-27 Koichiro Miyazima Procede de production de composes de liposomes
US5409704A (en) * 1985-06-26 1995-04-25 The Liposome Company, Inc. Liposomes comprising aminoglycoside phosphates and methods of production and use
IL79114A (en) * 1985-08-07 1990-09-17 Allergan Pharma Method and composition for making liposomes
US5622713A (en) * 1985-09-17 1997-04-22 The Regents Of The University Of California Method of detoxifying animal suffering from overdose
US4766046A (en) * 1985-09-27 1988-08-23 Liposome Technology, Inc. Stabilized liposome/amphotericin composition and method
US5041278A (en) * 1985-10-15 1991-08-20 The Liposome Company, Inc. Alpha tocopherol-based vesicles
US4861580A (en) * 1985-10-15 1989-08-29 The Liposome Company, Inc. Composition using salt form of organic acid derivative of alpha-tocopheral
IE58981B1 (en) * 1985-10-15 1993-12-15 Vestar Inc Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles
SE8505047L (sv) * 1985-10-25 1987-04-26 Nutritional Int Res Inst Fettemulsion
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US5252263A (en) * 1986-06-16 1993-10-12 The Liposome Company, Inc. Induction of asymmetry in vesicles
MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US4950432A (en) * 1987-10-16 1990-08-21 Board Of Regents, The University Of Texas System Polyene microlide pre-liposomal powders
US4946683A (en) * 1987-11-18 1990-08-07 Vestar, Inc. Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
DE68916439T2 (de) * 1988-10-05 1994-10-20 Vestar Inc Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens.
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
US5091187A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
US5246707A (en) * 1990-04-26 1993-09-21 Haynes Duncan H Sustained release delivery of water-soluble bio-molecules and drugs using phospholipid-coated microcrystals, microdroplets and high-concentration liposomes
DK0555229T3 (da) * 1990-07-31 1996-08-19 Liposome Co Inc Akkumulation af aminosyrer og peptider i liposomer
US5462740A (en) * 1993-09-17 1995-10-31 Athena Neurosciences, Inc. Rectally-administered, epileptic-seizure-inhibiting composition
US5840328A (en) * 1994-01-11 1998-11-24 The Liposome Company, Inc. Treatment using arachidonic acid metabolite and particulate formulations
WO1996009037A1 (fr) * 1994-09-23 1996-03-28 The Liposome Company, Inc. Procede de fabrication d'un liposome lyophilise
FR2733151B1 (fr) * 1995-04-20 1997-05-23 Seppic Sa Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines
US6117432A (en) * 1995-04-20 2000-09-12 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
US6689370B1 (en) 1995-04-20 2004-02-10 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
US20040208922A1 (en) * 1995-06-07 2004-10-21 The Regents Of The University Of California Method for loading lipid like vesicles with drugs or other chemicals
CA2234957C (fr) 1995-10-17 2006-12-19 Inge B. Henriksen Administration de medicaments insolubles
GB9609779D0 (en) 1996-05-10 1996-07-17 Univ Bruxelles Freeze dried liposome encapsulated amphiphilic drug compositions and a process for the preparation thereof
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US5827532A (en) * 1997-01-31 1998-10-27 The Reagents Of The University Of California Method for loading lipsomes with ionizable phosphorylated hydrophobic compounds, pharmaceutical preparations and a method for administering the preparations
IT1289938B1 (it) * 1997-02-20 1998-10-19 Angelini Ricerche Spa Preparazione farmaceutica comprendente liposomi liofilizzati in cui e' incapsulato un principio attivo altamente insolubile in acqua e
US6037323A (en) * 1997-09-29 2000-03-14 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6518412B1 (en) * 1997-09-29 2003-02-11 Jean-Louis Dasseux Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6046166A (en) * 1997-09-29 2000-04-04 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6004925A (en) 1997-09-29 1999-12-21 J. L. Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6287590B1 (en) 1997-10-02 2001-09-11 Esperion Therapeutics, Inc. Peptide/lipid complex formation by co-lyophilization
IL137734A0 (en) * 1998-02-11 2001-10-31 Res Triangle Pharm Ltd Method and composition for treatment of inflammatory conditions
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
AU764001B2 (en) 1998-05-29 2003-08-07 Skyepharma Canada Inc. Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
JP4198318B2 (ja) 1998-08-19 2008-12-17 ヤーゴテック アクチェンゲゼルシャフト プロポフォールの注射可能水性分散物
CA2349203C (fr) 1998-11-20 2013-05-21 Rtp Pharma Inc. Microparticules dispersibles stabilisees par phospholipides
EP1276465B1 (fr) 2000-04-20 2014-03-12 Jagotec AG Procede ameliore destine aux particules de medicament insolubles dans l'eau
US6653062B1 (en) * 2000-07-26 2003-11-25 Wisconsin Alumni Research Foundation Preservation and storage medium for biological materials
ATE424811T1 (de) 2000-08-31 2009-03-15 Jagotec Ag Gemahlene partikel
US8586094B2 (en) 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
ATE413164T1 (de) * 2000-11-09 2008-11-15 Neopharm Inc Sn-38-lipidkomplexe und verfahren zu ihrer verwendung
JP2004523552A (ja) * 2001-02-22 2004-08-05 スカイファーマ・カナダ・インコーポレーテッド 低減した摂食−絶食効果を伴うフィブラート−スタチンの組合わせ
WO2003030864A1 (fr) 2001-05-29 2003-04-17 Neopharm, Inc. Formulation liposomale d'irinotecan
AU2003296897A1 (en) * 2002-08-20 2004-05-04 Neopharm, Inc. Pharmaceutical formulations of camptothecine derivatives
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
CA2503087A1 (fr) * 2005-03-30 2006-09-30 Medicure International Inc. Formulations injectables de 5'-phosphate de pyridoxal et methode de preparation connexe
EP2537526A1 (fr) * 2006-06-01 2012-12-26 Institut de Cardiologie de Montréal Méthode et composé pour le traitement des sténoses valvulaires
RU2532222C2 (ru) 2009-02-16 2014-10-27 Серенис Терапьютикс Холдинг С.А, Миметики аполипопротеина а-i

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FR2081586A2 (en) * 1970-01-24 1971-12-10 Orsymonde Dehydrated pharmaceutical comps by - lyophilisation
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
IT1202370B (it) * 1976-07-12 1989-02-09 Hoffmann La Roche Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti
DE2656333C2 (de) * 1976-12-13 1985-08-08 Karl Prof. Dr.med. 7302 Ostfildern Theurer Verfahren zur Herstellung von Liposomen, welche Arzneistoffe enthalten
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
CH621479A5 (fr) * 1977-08-05 1981-02-13 Battelle Memorial Institute

Also Published As

Publication number Publication date
IE49615B1 (en) 1985-10-30
AR230178A1 (es) 1984-03-01
IE801281L (en) 1980-12-22
ZA803567B (en) 1981-06-24
NZ194047A (en) 1982-09-14
MC1336A1 (fr) 1981-04-21
FI801876A (fi) 1980-12-23
IL60326A0 (en) 1980-09-16
DK266680A (da) 1980-12-23
EP0021337A3 (en) 1981-04-22
NO801863L (no) 1980-12-22
PT71436B (en) 1981-10-23
PT71436A (en) 1980-07-01
US4411894A (en) 1983-10-25
NO155226B (no) 1986-11-24
DK155172B (da) 1989-02-27
ATE5508T1 (de) 1983-12-15
DE3065818D1 (en) 1984-01-12
DK155172C (da) 1989-09-18
ES8104720A1 (es) 1981-05-16
HU186296B (en) 1985-07-29
JPS567714A (en) 1981-01-27
PH16795A (en) 1984-02-28
KR830002327A (ko) 1983-05-28
AU534959B2 (en) 1984-02-23
CA1173360A (fr) 1984-08-28
AU5928980A (en) 1981-01-08
EP0021337A2 (fr) 1981-01-07
NO155226C (no) 1987-03-04
KR850001301B1 (ko) 1985-09-12
FI72875C (fi) 1987-08-10
FI72875B (fi) 1987-04-30
EP0021337B1 (fr) 1983-12-07
ES492676A0 (es) 1981-05-16

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