DK155172C - Fremgangsmaade til fremstilling af liposomholdige farmaceutiske praeparater - Google Patents

Fremgangsmaade til fremstilling af liposomholdige farmaceutiske praeparater

Info

Publication number
DK155172C
DK155172C DK266680A DK266680A DK155172C DK 155172 C DK155172 C DK 155172C DK 266680 A DK266680 A DK 266680A DK 266680 A DK266680 A DK 266680A DK 155172 C DK155172 C DK 155172C
Authority
DK
Denmark
Prior art keywords
liposomatic
procedure
preparation
pharmaceutical preparations
preparations
Prior art date
Application number
DK266680A
Other languages
English (en)
Other versions
DK266680A (da
DK155172B (da
Inventor
Juerg Schrank
Hans Steffen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK266680A publication Critical patent/DK266680A/da
Publication of DK155172B publication Critical patent/DK155172B/da
Application granted granted Critical
Publication of DK155172C publication Critical patent/DK155172C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK266680A 1979-06-22 1980-06-20 Fremgangsmaade til fremstilling af liposomholdige farmaceutiske praeparater DK155172C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH586379 1979-06-22
CH586379 1979-06-22

Publications (3)

Publication Number Publication Date
DK266680A DK266680A (da) 1980-12-23
DK155172B DK155172B (da) 1989-02-27
DK155172C true DK155172C (da) 1989-09-18

Family

ID=4300559

Family Applications (1)

Application Number Title Priority Date Filing Date
DK266680A DK155172C (da) 1979-06-22 1980-06-20 Fremgangsmaade til fremstilling af liposomholdige farmaceutiske praeparater

Country Status (21)

Country Link
US (1) US4411894A (da)
EP (1) EP0021337B1 (da)
JP (1) JPS567714A (da)
KR (1) KR850001301B1 (da)
AR (1) AR230178A1 (da)
AT (1) ATE5508T1 (da)
AU (1) AU534959B2 (da)
CA (1) CA1173360A (da)
DE (1) DE3065818D1 (da)
DK (1) DK155172C (da)
ES (1) ES492676A0 (da)
FI (1) FI72875C (da)
HU (1) HU186296B (da)
IE (1) IE49615B1 (da)
IL (1) IL60326A (da)
MC (1) MC1336A1 (da)
NO (1) NO155226C (da)
NZ (1) NZ194047A (da)
PH (1) PH16795A (da)
PT (1) PT71436B (da)
ZA (1) ZA803567B (da)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59152348A (ja) * 1983-02-19 1984-08-31 Kaken Pharmaceut Co Ltd ビフエニリルプロピオン酸エステル誘導体およびその製造法
JPH0768117B2 (ja) * 1983-05-06 1995-07-26 ベスター・インコーポレイテツド 薬剤放出調整用小胞製剤
US5186941A (en) * 1983-05-06 1993-02-16 Vestar, Inc. Vesicle formulation for the controlled release of therapeutic agents
CA1237670A (en) * 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
JPS601122A (ja) * 1983-06-20 1985-01-07 Green Cross Corp:The ビフエニリルプロピオン酸誘導体脂肪乳剤
CA1264162A (en) * 1984-03-15 1990-01-02 Manfred Breuninger Glycerol ether phosphatides
JPS60208910A (ja) * 1984-03-31 1985-10-21 Green Cross Corp:The 水難溶性薬物・リン脂質複合体の製造方法
US4891208A (en) * 1985-04-10 1990-01-02 The Liposome Company, Inc. Steroidal liposomes
US5231112A (en) 1984-04-12 1993-07-27 The Liposome Company, Inc. Compositions containing tris salt of cholesterol hemisuccinate and antifungal
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
CA1264668A (en) * 1984-06-20 1990-01-23 Pieter R. Cullis Extrusion techniques for producing liposomes
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
CA1270198A (en) * 1984-08-08 1990-06-12 Marcel B. Bally Encapsulation of antineoplastic agents in liposomes
US5077056A (en) * 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
JPS61100518A (ja) * 1984-10-22 1986-05-19 Ono Pharmaceut Co Ltd ジミリストイルホスフアチジルコリンを主成分とする凍結乾燥されたリポゾ−ム製剤
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
JPS62501631A (ja) * 1985-01-11 1987-07-02 ザ・リ−ジェンツ・オブ・ジ・ユニバ−シィティ・オブ・カリフォルニア リポソ−ムの保持法
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
CA1256372A (en) * 1985-04-11 1989-06-27 Koichiro Miyazima Process for producing liposome composition
US5409704A (en) * 1985-06-26 1995-04-25 The Liposome Company, Inc. Liposomes comprising aminoglycoside phosphates and methods of production and use
IL79114A (en) * 1985-08-07 1990-09-17 Allergan Pharma Method and composition for making liposomes
US5622713A (en) * 1985-09-17 1997-04-22 The Regents Of The University Of California Method of detoxifying animal suffering from overdose
US4766046A (en) * 1985-09-27 1988-08-23 Liposome Technology, Inc. Stabilized liposome/amphotericin composition and method
IE58981B1 (en) * 1985-10-15 1993-12-15 Vestar Inc Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles
US4861580A (en) * 1985-10-15 1989-08-29 The Liposome Company, Inc. Composition using salt form of organic acid derivative of alpha-tocopheral
US5041278A (en) * 1985-10-15 1991-08-20 The Liposome Company, Inc. Alpha tocopherol-based vesicles
SE8505047L (sv) * 1985-10-25 1987-04-26 Nutritional Int Res Inst Fettemulsion
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US5252263A (en) * 1986-06-16 1993-10-12 The Liposome Company, Inc. Induction of asymmetry in vesicles
MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US4950432A (en) * 1987-10-16 1990-08-21 Board Of Regents, The University Of Texas System Polyene microlide pre-liposomal powders
US4946683A (en) * 1987-11-18 1990-08-07 Vestar, Inc. Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
JP2792702B2 (ja) * 1988-10-05 1998-09-03 ネクスター・フアーマシユーテイカルズ・インコーポレイテツド 乾燥時に改善された安定性を示すリポソームの調製方法
US5246707A (en) * 1990-04-26 1993-09-21 Haynes Duncan H Sustained release delivery of water-soluble bio-molecules and drugs using phospholipid-coated microcrystals, microdroplets and high-concentration liposomes
US5091187A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
EP0555229B1 (en) * 1990-07-31 1996-06-05 The Liposome Company, Inc. Accumulation of amino acids and peptides into liposomes
US5462740A (en) * 1993-09-17 1995-10-31 Athena Neurosciences, Inc. Rectally-administered, epileptic-seizure-inhibiting composition
US5840328A (en) * 1994-01-11 1998-11-24 The Liposome Company, Inc. Treatment using arachidonic acid metabolite and particulate formulations
WO1996009037A1 (en) * 1994-09-23 1996-03-28 The Liposome Company, Inc. Method of producing a lyophilized liposome product
US6117432A (en) * 1995-04-20 2000-09-12 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
FR2733151B1 (fr) * 1995-04-20 1997-05-23 Seppic Sa Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines
US6689370B1 (en) 1995-04-20 2004-02-10 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
US20040208922A1 (en) * 1995-06-07 2004-10-21 The Regents Of The University Of California Method for loading lipid like vesicles with drugs or other chemicals
JP5038552B2 (ja) 1995-10-17 2012-10-03 オバン・エナジー・リミテッド 不溶性薬物の送達
GB9609779D0 (en) 1996-05-10 1996-07-17 Univ Bruxelles Freeze dried liposome encapsulated amphiphilic drug compositions and a process for the preparation thereof
US7255877B2 (en) 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US5827532A (en) * 1997-01-31 1998-10-27 The Reagents Of The University Of California Method for loading lipsomes with ionizable phosphorylated hydrophobic compounds, pharmaceutical preparations and a method for administering the preparations
IT1289938B1 (it) * 1997-02-20 1998-10-19 Angelini Ricerche Spa Preparazione farmaceutica comprendente liposomi liofilizzati in cui e' incapsulato un principio attivo altamente insolubile in acqua e
US6046166A (en) * 1997-09-29 2000-04-04 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6004925A (en) 1997-09-29 1999-12-21 J. L. Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6518412B1 (en) 1997-09-29 2003-02-11 Jean-Louis Dasseux Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6037323A (en) * 1997-09-29 2000-03-14 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6287590B1 (en) 1997-10-02 2001-09-11 Esperion Therapeutics, Inc. Peptide/lipid complex formation by co-lyophilization
AU762246B2 (en) * 1998-02-11 2003-06-19 Rtp Pharma Corporation Method and composition for treatment of inflammatory conditions
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
JP2002516267A (ja) 1998-05-29 2002-06-04 アールティーピー・ファーマ・インコーポレーテッド 熱的に保護された微粒子組成物及びその最終蒸気滅菌
EP1105096B1 (en) 1998-08-19 2003-10-29 Skyepharma Canada Inc. Injectable aqueous dispersions of propofol
US7939105B2 (en) 1998-11-20 2011-05-10 Jagotec Ag Process for preparing a rapidly dispersing solid drug dosage form
AU2001257115B2 (en) 2000-04-20 2005-01-27 Rtp Pharma Inc. Improved water-insoluble drug particle process
US6653062B1 (en) * 2000-07-26 2003-11-25 Wisconsin Alumni Research Foundation Preservation and storage medium for biological materials
EP1313451B1 (en) 2000-08-31 2009-03-11 Jagotec AG Milled particles
US8586094B2 (en) 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
CZ20031515A3 (cs) * 2000-11-09 2003-09-17 Neopharm, Inc. Komplexy SN-38 s lipidem a způsob jejich použití
ATE357216T1 (de) * 2001-02-22 2007-04-15 Jagotec Ag Fibrat-statin kombinationen mit verminderten von der nahrungsaufnahme abhängigen auswirkungen
WO2003030864A1 (en) 2001-05-29 2003-04-17 Neopharm, Inc. Liposomal formulation of irinotecan
WO2004035032A2 (en) * 2002-08-20 2004-04-29 Neopharm, Inc. Pharmaceutical formulations of camptothecine derivatives
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
CA2503087A1 (en) * 2005-03-30 2006-09-30 Medicure International Inc. Intravenous formulations of pyridoxal 5'-phosphate and method of preparation
ES2402823T3 (es) * 2006-06-01 2013-05-09 Institut De Cardiologie De Montreal Compuesto para uso en el tratamiento de estenosis valvular
SMT201700203T1 (it) 2009-02-16 2017-05-08 Cerenis Therapeutics Holding Sa Mimetici di apolipoproteina a-i

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081586A2 (en) * 1970-01-24 1971-12-10 Orsymonde Dehydrated pharmaceutical comps by - lyophilisation
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
IT1202370B (it) * 1976-07-12 1989-02-09 Hoffmann La Roche Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti
DE2656333C2 (de) * 1976-12-13 1985-08-08 Karl Prof. Dr.med. 7302 Ostfildern Theurer Verfahren zur Herstellung von Liposomen, welche Arzneistoffe enthalten
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
CH621479A5 (da) * 1977-08-05 1981-02-13 Battelle Memorial Institute

Also Published As

Publication number Publication date
KR850001301B1 (ko) 1985-09-12
NO155226C (no) 1987-03-04
EP0021337A2 (de) 1981-01-07
IE49615B1 (en) 1985-10-30
IL60326A0 (en) 1980-09-16
EP0021337B1 (de) 1983-12-07
HU186296B (en) 1985-07-29
ATE5508T1 (de) 1983-12-15
IL60326A (en) 1983-09-30
US4411894A (en) 1983-10-25
IE801281L (en) 1980-12-22
AU5928980A (en) 1981-01-08
JPS567714A (en) 1981-01-27
FI72875B (fi) 1987-04-30
ES8104720A1 (es) 1981-05-16
DK266680A (da) 1980-12-23
NO801863L (no) 1980-12-22
NZ194047A (en) 1982-09-14
CA1173360A (en) 1984-08-28
PT71436A (en) 1980-07-01
PT71436B (en) 1981-10-23
ES492676A0 (es) 1981-05-16
PH16795A (en) 1984-02-28
ZA803567B (en) 1981-06-24
NO155226B (no) 1986-11-24
MC1336A1 (fr) 1981-04-21
DK155172B (da) 1989-02-27
AU534959B2 (en) 1984-02-23
KR830002327A (ko) 1983-05-28
EP0021337A3 (en) 1981-04-22
FI801876A7 (fi) 1980-12-23
AR230178A1 (es) 1984-03-01
DE3065818D1 (en) 1984-01-12
FI72875C (fi) 1987-08-10

Similar Documents

Publication Publication Date Title
DK155172C (da) Fremgangsmaade til fremstilling af liposomholdige farmaceutiske praeparater
DK460283A (da) Fremgangsmaade til fremstilling af topiske farmaceutiske praeparater
DK546080A (da) Fremgangsmaade til fremstilling af galactosaccharosederivater
DK29681A (da) Fremgangsmaade til fremstilling af immunogammaglobulin
DK365280A (da) Fremgangsmaade til fremstilling af ftaliminderivater
DK311580A (da) Fremgangsmaade til fremstilling af oxoalkylxanthiner
DK552180A (da) Fremgangsmaade til fremstilling af tetrapeptidsemikarbazidderivater
DK274580A (da) Fremgangsmaade til fremstilling af tripeptidamider
DK149623C (da) Fremgangsmaade til fremstilling af alfa-hydroxycarboxylsyreamider
DK394080A (da) Fremgangsmaade til fremstilling af carbostyrilderivater
DK153791C (da) Fremgangsmaade til fremstilling af 7-hydroxycumaraner
DK481280A (da) Fremgangsmaade til fremstilling af piperidylbenzimidazolinonderivater
DK327280A (da) Fremgangsmaade til fremstilling af peptidderivater
DK280282A (da) Fremgangsmaade til fremstilling af farmaceutiske praeparater indeholdende ergotalkaloider
DK262180A (da) Fremgangsmaade til fremstilling af alkyl-2-chlorpropionater
DK427281A (da) Fremgangsmaade til fremstilling af terapeutiske praeparater
DK51282A (da) Fremgangsmaade til fremstilling af farmaceutiske praeparater
DK187980A (da) Fremgangsmaade til fremstilling af benzimidazolderivater
DK274680A (da) Fremgangsmaade til fremstilling af tripeptidamider
DK304080A (da) Fremgangsmaade til fremstilling af pyrazoloindazolderivater
DK222880A (da) Fremgangsmaade til fremstilling af anthracyclinonderivater
DK47681A (da) Fremgangsmaade til fremstilling af farmaceutiske praeparater
DK228381A (da) Fremgangsmaade til fremstilling af antidiarretiske farmaceutiske praeparater
DK546180A (da) Fremgangsmaade til fremstilling af triazepinderivater
DK318280A (da) Fremgangsmaade til fremstilling af naphthyridinderivater

Legal Events

Date Code Title Description
PBP Patent lapsed