IL60243A - Pharmaceutical compositions containing 4-heteroaroyl and aroylimidazol-2-ones,some novel compounds of this type and their preparation - Google Patents
Pharmaceutical compositions containing 4-heteroaroyl and aroylimidazol-2-ones,some novel compounds of this type and their preparationInfo
- Publication number
- IL60243A IL60243A IL60243A IL6024380A IL60243A IL 60243 A IL60243 A IL 60243A IL 60243 A IL60243 A IL 60243A IL 6024380 A IL6024380 A IL 6024380A IL 60243 A IL60243 A IL 60243A
- Authority
- IL
- Israel
- Prior art keywords
- aroylimidazol
- heteroaroyl
- ones
- preparation
- type
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4980879A | 1979-06-18 | 1979-06-18 | |
US11920780A | 1980-02-07 | 1980-02-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL60243A0 IL60243A0 (en) | 1980-09-16 |
IL60243A true IL60243A (en) | 1987-01-30 |
Family
ID=26727558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL60243A IL60243A (en) | 1979-06-18 | 1980-06-06 | Pharmaceutical compositions containing 4-heteroaroyl and aroylimidazol-2-ones,some novel compounds of this type and their preparation |
Country Status (20)
Country | Link |
---|---|
AT (1) | AT375349B (it) |
AU (1) | AU532783B2 (it) |
CA (1) | CA1132554A (it) |
CH (1) | CH646155A5 (it) |
DE (1) | DE3021792A1 (it) |
DK (1) | DK160269C (it) |
ES (1) | ES8105299A1 (it) |
FR (1) | FR2459233A1 (it) |
GB (1) | GB2055364B (it) |
HK (1) | HK61486A (it) |
HU (1) | HU186736B (it) |
IE (1) | IE50646B1 (it) |
IL (1) | IL60243A (it) |
IT (1) | IT1143922B (it) |
MY (1) | MY8600709A (it) |
NL (2) | NL193752C (it) |
NO (1) | NO152841C (it) |
NZ (1) | NZ193935A (it) |
PH (1) | PH18683A (it) |
SE (2) | SE447107B (it) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH18106A (en) * | 1981-02-18 | 1985-03-21 | Merrell Dow Pharma | Novel-4-aroylimidazol-2-ones |
US4405628A (en) * | 1981-03-05 | 1983-09-20 | Merrell Dow Pharmaceuticals Inc. | 4-Pyridylimidazolones and method of use |
US4381393A (en) * | 1981-05-04 | 1983-04-26 | Merrell Dow Pharmaceuticals Inc. | 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones |
GB2097792B (en) * | 1981-05-04 | 1985-01-03 | Merrell Dow Pharma | 1,3-dihydro-2h-imidazol-2-ones |
US4329470A (en) | 1981-05-04 | 1982-05-11 | Merrell Dow Pharmaceuticals Inc. | 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives |
US4371737A (en) * | 1981-05-04 | 1983-02-01 | Merrell Dow Pharmaceuticals Inc. | 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives |
US4526981A (en) * | 1981-05-04 | 1985-07-02 | Merrell Dow Pharmaceuticals Inc. | [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates |
US4329471A (en) * | 1981-05-04 | 1982-05-11 | Merrell Dow Pharmaceuticals Inc. | 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones |
US4410540A (en) * | 1981-11-04 | 1983-10-18 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic 4-aroylimidazolidin-2-ones |
US4367236A (en) | 1981-11-04 | 1983-01-04 | Merrell Dow Pharmaceuticals Inc. | Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US20060025463A1 (en) * | 2004-03-22 | 2006-02-02 | Michael Bristow | Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases |
US20060030611A1 (en) * | 2004-03-22 | 2006-02-09 | Myogen, Inc. | Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases |
EP1956906A4 (en) | 2005-11-09 | 2009-12-30 | Combinatorx Inc | METHODS, COMPOSITIONS AND KITS FOR THE TREATMENT OF PATHOLOGIES |
DK2170930T3 (da) | 2007-06-04 | 2012-11-05 | Synergy Pharmaceuticals Inc | Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
ES2664873T3 (es) | 2011-03-01 | 2018-04-23 | Synergy Pharmaceuticals Inc. | Proceso de preparación de agonistas de guanilato ciclasa C |
EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
EP2958577A2 (en) | 2013-02-25 | 2015-12-30 | Synergy Pharmaceuticals Inc. | Guanylate cyclase receptor agonists for use in colonic cleansing |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
KR102272746B1 (ko) | 2013-06-05 | 2021-07-08 | 보슈 헬스 아일랜드 리미티드 | 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법 |
KR20220147691A (ko) | 2013-08-09 | 2022-11-03 | 알데릭스, 인코포레이티드 | 인산염 수송을 억제하기 위한 화합물 및 방법 |
JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス, インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
CN114539157B (zh) * | 2022-03-03 | 2023-12-22 | 曲靖师范学院 | 一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2441933A (en) * | 1945-07-30 | 1948-05-18 | Hoffmann La Roche | Substituted imidazolones and process of making them |
-
1980
- 1980-06-04 NZ NZ193935A patent/NZ193935A/en unknown
- 1980-06-05 IE IE1162/80A patent/IE50646B1/en not_active IP Right Cessation
- 1980-06-06 IL IL60243A patent/IL60243A/xx unknown
- 1980-06-06 AU AU59118/80A patent/AU532783B2/en not_active Expired
- 1980-06-06 SE SE8004253A patent/SE447107B/sv not_active IP Right Cessation
- 1980-06-09 ES ES492255A patent/ES8105299A1/es not_active Expired
- 1980-06-11 DE DE19803021792 patent/DE3021792A1/de active Granted
- 1980-06-13 AT AT0314280A patent/AT375349B/de not_active IP Right Cessation
- 1980-06-16 CH CH462780A patent/CH646155A5/de not_active IP Right Cessation
- 1980-06-16 PH PH24143A patent/PH18683A/en unknown
- 1980-06-17 HU HU801506A patent/HU186736B/hu unknown
- 1980-06-17 IT IT48997/80A patent/IT1143922B/it active Protection Beyond IP Right Term
- 1980-06-17 NO NO801796A patent/NO152841C/no unknown
- 1980-06-17 FR FR8013434A patent/FR2459233A1/fr active Granted
- 1980-06-17 DK DK259080A patent/DK160269C/da not_active IP Right Cessation
- 1980-06-17 CA CA354,197A patent/CA1132554A/en not_active Expired
- 1980-06-17 NL NL8003498A patent/NL193752C/nl not_active IP Right Cessation
- 1980-06-18 GB GB8019898A patent/GB2055364B/en not_active Expired
-
1985
- 1985-03-25 SE SE8501452A patent/SE464559B/sv not_active IP Right Cessation
-
1986
- 1986-08-21 HK HK614/86A patent/HK61486A/xx not_active IP Right Cessation
- 1986-12-30 MY MY709/86A patent/MY8600709A/xx unknown
-
2000
- 2000-09-04 NL NL300015C patent/NL300015I1/nl unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed |