IL59265A - Crystalline solvates of 4'-nitrobenzyl 7-phenoxyacetamido-3-hydroxy-3-cephem-4-carboxylate and its sulfoxide and process for their preparation - Google Patents

Crystalline solvates of 4'-nitrobenzyl 7-phenoxyacetamido-3-hydroxy-3-cephem-4-carboxylate and its sulfoxide and process for their preparation

Info

Publication number
IL59265A
IL59265A IL59265A IL5926580A IL59265A IL 59265 A IL59265 A IL 59265A IL 59265 A IL59265 A IL 59265A IL 5926580 A IL5926580 A IL 5926580A IL 59265 A IL59265 A IL 59265A
Authority
IL
Israel
Prior art keywords
phenoxyacetamido
cephem
nitrobenzyl
carboxylate
sulfoxide
Prior art date
Application number
IL59265A
Other languages
English (en)
Other versions
IL59265A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL59265A0 publication Critical patent/IL59265A0/xx
Publication of IL59265A publication Critical patent/IL59265A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/30—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino-radical acylated by an araliphatic carboxylic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL59265A 1979-02-01 1980-01-29 Crystalline solvates of 4'-nitrobenzyl 7-phenoxyacetamido-3-hydroxy-3-cephem-4-carboxylate and its sulfoxide and process for their preparation IL59265A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US846879A 1979-02-01 1979-02-01

Publications (2)

Publication Number Publication Date
IL59265A0 IL59265A0 (en) 1980-05-30
IL59265A true IL59265A (en) 1983-05-15

Family

ID=21731772

Family Applications (1)

Application Number Title Priority Date Filing Date
IL59265A IL59265A (en) 1979-02-01 1980-01-29 Crystalline solvates of 4'-nitrobenzyl 7-phenoxyacetamido-3-hydroxy-3-cephem-4-carboxylate and its sulfoxide and process for their preparation

Country Status (32)

Country Link
EP (1) EP0014565B1 (fr)
JP (1) JPS55104288A (fr)
KR (1) KR830001890B1 (fr)
AR (1) AR228342A1 (fr)
AT (1) AT366052B (fr)
AU (1) AU532573B2 (fr)
BE (1) BE881423A (fr)
BG (1) BG32857A3 (fr)
CA (1) CA1142173A (fr)
CH (1) CH647525A5 (fr)
CS (1) CS214694B2 (fr)
DD (1) DD148953A5 (fr)
DE (1) DE3062095D1 (fr)
DK (1) DK159157C (fr)
ES (1) ES8103098A1 (fr)
FI (1) FI68239C (fr)
FR (1) FR2447925A1 (fr)
GB (1) GB2041934B (fr)
GR (1) GR72785B (fr)
HU (2) HU181761B (fr)
IE (1) IE49374B1 (fr)
IL (1) IL59265A (fr)
IT (1) IT1130239B (fr)
LU (1) LU82118A1 (fr)
NZ (1) NZ192750A (fr)
PH (1) PH15152A (fr)
PL (1) PL122609B1 (fr)
PT (1) PT70742A (fr)
RO (2) RO79181A (fr)
SU (2) SU897109A3 (fr)
YU (1) YU22480A (fr)
ZA (1) ZA80523B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3128949A1 (de) * 1981-07-22 1983-02-10 Basf Ag, 6700 Ludwigshafen Lichtempfindliche aufzeichnungsmaterialien zur herstellung von abriebs- und kratzfesten tiefdruckformen sowie verfahren zur herstellung von tiefdruckformen mittels dieser aufzeichnungsmaterialien
JPS6011491A (ja) * 1983-03-04 1985-01-21 Shionogi & Co Ltd セフアロチンナトリウムの結晶性凍結乾燥粉末の製造法
US4782144A (en) * 1987-09-14 1988-11-01 Eli Lilly And Company 1-carba(dethia)-3-hydroxy-3-cephem ester crystalline and crystalline solvate thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985747A (en) * 1974-05-24 1976-10-12 Bristol-Myers Company Crystalline sesquihydrate of 7-[D-α-amino-α-(p-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
US4044002A (en) * 1976-06-09 1977-08-23 Eli Lilly And Company Reduction process for cephalosporin sulfoxides

Also Published As

Publication number Publication date
KR830001890B1 (ko) 1983-09-17
EP0014565A1 (fr) 1980-08-20
AT366052B (de) 1982-03-10
BG32857A3 (en) 1982-10-15
BE881423A (fr) 1980-07-30
FR2447925B1 (fr) 1984-02-03
LU82118A1 (fr) 1980-04-23
DD148953A5 (de) 1981-06-17
FR2447925A1 (fr) 1980-08-29
RO83702B (ro) 1984-03-30
ZA80523B (en) 1981-09-30
RO79181A (fr) 1982-06-25
HU182095B (en) 1983-12-28
YU22480A (en) 1983-02-28
NZ192750A (en) 1982-05-25
SU938740A3 (ru) 1982-06-23
PH15152A (en) 1982-08-24
FI800300A (fi) 1980-08-02
SU897109A3 (ru) 1982-01-07
PT70742A (en) 1980-02-01
AR228342A1 (es) 1983-02-28
ES488229A0 (es) 1981-02-16
FI68239C (fi) 1985-08-12
IE800191L (en) 1980-08-01
GR72785B (fr) 1983-12-05
CH647525A5 (fr) 1985-01-31
JPH0128035B2 (fr) 1989-05-31
DK159157C (da) 1991-02-11
KR830001951A (ko) 1983-05-21
CA1142173A (fr) 1983-03-01
EP0014565B1 (fr) 1983-02-23
HU181761B (en) 1983-11-28
PL122609B1 (en) 1982-08-31
IT1130239B (it) 1986-06-11
GB2041934A (en) 1980-09-17
AU5502680A (en) 1980-08-07
GB2041934B (en) 1983-03-23
ATA49980A (de) 1981-07-15
PL221748A1 (fr) 1980-12-15
FI68239B (fi) 1985-04-30
JPS55104288A (en) 1980-08-09
IL59265A0 (en) 1980-05-30
RO83702A (fr) 1984-03-15
AU532573B2 (en) 1983-10-06
DE3062095D1 (en) 1983-03-31
ES8103098A1 (es) 1981-02-16
DK159157B (da) 1990-09-10
IE49374B1 (en) 1985-09-18
IT8019607A0 (it) 1980-01-31
DK41180A (da) 1980-08-02
CS214694B2 (en) 1982-05-28

Similar Documents

Publication Publication Date Title
YU42817B (en) Process for obtaining new derivatives of oxazolidone and thiazolidone
ZA80269B (en) Pharmaceutical compositions consisting or consisting essentially of liposomers and processes for making same
GB2144418B (en) Thiazolinoazetidinone derivatives and process for the preparation of the same
PT85027A (en) Process for the preparation of substituted 3-amino-2-benzoylcyclohexen-2-ones and of herbicidal compositions containing them
EP0105494A3 (en) Process for the preparation of benzoxazolyl and benzothiazolyl phenoxy-propionic-acid derivatives
IL85706A (en) Process for the preparation of nitroethene derivatives and novel intermediate compounds therefor
GR871489B (en) Process for the preparation of sunscreen composition and compounds for use therein
GB2051119B (en) Preparation of 2 3-dimethylbutene-2
IL59265A (en) Crystalline solvates of 4'-nitrobenzyl 7-phenoxyacetamido-3-hydroxy-3-cephem-4-carboxylate and its sulfoxide and process for their preparation
JPS5640620A (en) Manufacture of 1*22dichloroethane
JPS55143942A (en) Manufacture of 2**6**dialkyllnnalkoxymethyll 22chlorooacetoanilide
DE3067697D1 (en) 1-azolyl-1-halogen-alkan-2-ones and process for the preparation of 1-azolyl-1-phenoxy-alkan-2-ones
HU184009B (en) Process for the preparation of 4'-deoxy-4-dezacetyl-leurosidine and vincristine derivatives
DE3063395D1 (en) Halogenated beta-lactam compounds and process for their preparation
IL59143A0 (en) Process and intermediates for the preparation of 7-acylindolin-2-ones
JPS55164634A (en) Manufacture of 1*22dichloroethane
NZ194316A (en) Preparation of 15-hydroxyimino-e-homoeburnane derivatives and 15-halo-e-homoeburnane precursors therein
JPS55154960A (en) Manufacture of 55mercaptoo1*2*33triazole
JPS5615233A (en) Manufacture of 33 and 44formyltricycloo *5*2*1*0**decenee8
JPS5616428A (en) Manufacture of 1*11dichloroalkene
JPS55141423A (en) Manufacture of 22 and 44hydroxyybenzylalcohol
YU184688A (en) Process for obtaining monohydrates and solvates of new beat-lactamic antibiotic
PT71146B (en) Method and composition for preparation of h-sar-lys-sar-gln-nh2
JPS5639017A (en) Novel use of 6*77benzomorphane derivative
PT72083A (en) Process for the preparation of fungicide sulfonyl-and sulfinylacetanilides and fungicide compositions thereof

Legal Events

Date Code Title Description
KB Patent renewed