IL58489A0 - The production of oxymorphone - Google Patents
The production of oxymorphoneInfo
- Publication number
- IL58489A0 IL58489A0 IL58489A IL5848979A IL58489A0 IL 58489 A0 IL58489 A0 IL 58489A0 IL 58489 A IL58489 A IL 58489A IL 5848979 A IL5848979 A IL 5848979A IL 58489 A0 IL58489 A0 IL 58489A0
- Authority
- IL
- Israel
- Prior art keywords
- oxymorphone
- production
- Prior art date
Links
- UQCNKQCJZOAFTQ-ISWURRPUSA-N Oxymorphone Chemical compound O([C@H]1C(CC[C@]23O)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O UQCNKQCJZOAFTQ-ISWURRPUSA-N 0.000 title 1
- 229960005118 oxymorphone Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Polarising Elements (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95305678A | 1978-10-19 | 1978-10-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL58489A0 true IL58489A0 (en) | 1980-01-31 |
Family
ID=25493512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL58489A IL58489A0 (en) | 1978-10-19 | 1979-10-18 | The production of oxymorphone |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS55501025A (cs) |
| AU (1) | AU5189779A (cs) |
| BE (1) | BE879494A (cs) |
| CA (1) | CA1108132A (cs) |
| CS (1) | CS211364B2 (cs) |
| DK (1) | DK258280A (cs) |
| ES (1) | ES485154A1 (cs) |
| FI (1) | FI793235A7 (cs) |
| FR (1) | FR2439201A1 (cs) |
| GB (1) | GB2049680A (cs) |
| IL (1) | IL58489A0 (cs) |
| IT (1) | IT7969032A0 (cs) |
| NL (1) | NL7920126A (cs) |
| NO (1) | NO793297L (cs) |
| SE (1) | SE8004454L (cs) |
| WO (1) | WO1980000841A1 (cs) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4795813A (en) * | 1981-08-17 | 1989-01-03 | The Florida Board Of Regents On Behalf Of The Florida State University | Synthesis of derivatives of codeine and other 3-O-alkylmorphines |
| US5668285A (en) * | 1986-10-31 | 1997-09-16 | The United States Of America As Represented By The Department Of Health And Human Services | Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates |
| FR2636330B1 (fr) * | 1988-09-13 | 1990-11-30 | Sanofi Sa | Procede de preparation de derives de morphinane |
| DE69033035T2 (de) * | 1989-10-16 | 1999-08-05 | The United States of America, represented by the Secretary, U.S. Department of Commerce, Washington, D.C. | Totale synthese von northebain-, normorphin-, noroxymorphon-enantiomeren und -derivaten via n-nor-zwischenverbindungen |
| US8329216B2 (en) | 2001-07-06 | 2012-12-11 | Endo Pharmaceuticals Inc. | Oxymorphone controlled release formulations |
| KR20030034171A (ko) | 2001-07-06 | 2003-05-01 | 엔도 파마슈티걸즈, 인크. | 옥시모르폰 제어 방출 제형 |
| DK1404331T3 (da) | 2001-07-06 | 2008-01-28 | Penwest Pharmaceuticals Co | Sustained release-formuleringer af oxymorphon |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| JP5695296B2 (ja) | 2006-03-02 | 2015-04-01 | マリンクロッド エルエルシー | 低レベルのアルファ，ベータ−不飽和ケトン化合物を伴うモルフィナン−６−オン生成物の製造方法 |
| TWI454288B (zh) | 2008-01-25 | 2014-10-01 | Gruenenthal Chemie | 藥物劑型 |
| ES2599031T3 (es) | 2008-05-09 | 2017-01-31 | Grünenthal GmbH | Proceso para la preparación de una formulación de polvo intermedia y una forma de dosificación solida final utilizando un paso de congelación por pulverización |
| BR112012001466A2 (pt) | 2009-07-22 | 2020-08-11 | Grünenthal GmbH | forma de dosagem resistente à falsificação para opioides sensíveis à oxidação, seu processo de fabricação, e embalagem |
| ES2534908T3 (es) | 2009-07-22 | 2015-04-30 | Grünenthal GmbH | Forma de dosificación de liberación controlada extruida por fusión en caliente |
| CA2808219C (en) | 2010-09-02 | 2019-05-14 | Gruenenthal Gmbh | Tamper resistant dosage form comprising inorganic salt |
| WO2012028318A1 (en) | 2010-09-02 | 2012-03-08 | Grünenthal GmbH | Tamper resistant dosage form comprising an anionic polymer |
| JP6063462B2 (ja) | 2011-07-29 | 2017-01-18 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 即時薬剤放出を提供するタンパーレジスタント錠剤 |
| BR112014002022A2 (pt) | 2011-07-29 | 2017-02-21 | Gruenenthal Gmbh | comprimido resistente à violação proporcionando liberação de fármaco imediata |
| BR112014019988A8 (pt) | 2012-02-28 | 2017-07-11 | Gruenenthal Gmbh | Forma de dosagem resistente a socamento compreendendo um composto farmacologicamente ativo e um polímero aniônico |
| LT2838512T (lt) | 2012-04-18 | 2018-11-12 | GrĆ¼nenthal GmbH | Pažeidimui atspari ir dozės atpalaidavimo nuokrypiui atspari farmacinė vaisto forma |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| MX2015016254A (es) | 2013-05-29 | 2016-04-20 | Gruenenthal Gmbh | Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal. |
| AU2014273227B2 (en) | 2013-05-29 | 2019-08-15 | Grunenthal Gmbh | Tamper-resistant dosage form containing one or more particles |
| AU2014289187B2 (en) | 2013-07-12 | 2019-07-11 | Grunenthal Gmbh | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
| HK1224189A1 (zh) | 2013-11-26 | 2017-08-18 | Grünenthal GmbH | 通过低温研磨制备粉状药物组合物 |
| WO2015173195A1 (en) | 2014-05-12 | 2015-11-19 | Grünenthal GmbH | Tamper resistant immediate release capsule formulation comprising tapentadol |
| US9872835B2 (en) | 2014-05-26 | 2018-01-23 | Grünenthal GmbH | Multiparticles safeguarded against ethanolic dose-dumping |
| WO2016170097A1 (en) | 2015-04-24 | 2016-10-27 | Grünenthal GmbH | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
| CA2998259A1 (en) | 2015-09-10 | 2017-03-16 | Grunenthal Gmbh | Protecting oral overdose with abuse deterrent immediate release formulations |
| EP3252055B1 (en) | 2016-05-31 | 2018-09-19 | Alcaliber Investigacion Desarrollo e Innovacion SLU | Process for obtaining 3,14-diacetyloxymorphone from oripavine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3249616A (en) * | 1966-05-03 | Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof | ||
| US2806033A (en) * | 1955-08-03 | 1957-09-10 | Lewenstein | Morphine derivative |
| US3775414A (en) * | 1972-05-10 | 1973-11-27 | Bristol Myers Co | Process for the preparation of 14-hydroxymorphinan derivatives |
-
1979
- 1979-10-12 NO NO793297A patent/NO793297L/no unknown
- 1979-10-18 JP JP50190279A patent/JPS55501025A/ja active Pending
- 1979-10-18 AU AU51897/79A patent/AU5189779A/en not_active Abandoned
- 1979-10-18 BE BE0/197710A patent/BE879494A/fr unknown
- 1979-10-18 WO PCT/US1979/000862 patent/WO1980000841A1/en not_active Ceased
- 1979-10-18 GB GB8014422A patent/GB2049680A/en not_active Withdrawn
- 1979-10-18 IL IL58489A patent/IL58489A0/xx unknown
- 1979-10-18 CA CA337,908A patent/CA1108132A/en not_active Expired
- 1979-10-18 NL NL7920126A patent/NL7920126A/nl unknown
- 1979-10-18 FR FR7925895A patent/FR2439201A1/fr not_active Withdrawn
- 1979-10-18 FI FI793235A patent/FI793235A7/fi not_active Application Discontinuation
- 1979-10-18 ES ES485154A patent/ES485154A1/es not_active Expired
- 1979-10-18 IT IT7969032A patent/IT7969032A0/it unknown
- 1979-10-19 CS CS797115A patent/CS211364B2/cs unknown
-
1980
- 1980-06-16 SE SE8004454A patent/SE8004454L/xx not_active Application Discontinuation
- 1980-06-17 DK DK258280A patent/DK258280A/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7920126A (nl) | 1980-08-29 |
| NO793297L (no) | 1980-04-22 |
| CS211364B2 (en) | 1982-02-26 |
| DK258280A (da) | 1980-06-17 |
| SE8004454L (sv) | 1980-06-16 |
| BE879494A (fr) | 1980-02-15 |
| IT7969032A0 (it) | 1979-10-18 |
| JPS55501025A (cs) | 1980-11-27 |
| ES485154A1 (es) | 1980-06-16 |
| CA1108132A (en) | 1981-09-01 |
| FI793235A7 (fi) | 1981-01-01 |
| FR2439201A1 (fr) | 1980-05-16 |
| WO1980000841A1 (en) | 1980-05-01 |
| GB2049680A (en) | 1980-12-31 |
| AU5189779A (en) | 1980-04-24 |
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