DK258280A - Fremgangsmaade til fremstilling af oxymorfon - Google Patents
Fremgangsmaade til fremstilling af oxymorfonInfo
- Publication number
- DK258280A DK258280A DK258280A DK258280A DK258280A DK 258280 A DK258280 A DK 258280A DK 258280 A DK258280 A DK 258280A DK 258280 A DK258280 A DK 258280A DK 258280 A DK258280 A DK 258280A
- Authority
- DK
- Denmark
- Prior art keywords
- oxymorphone
- procedure
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Polarising Elements (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95305678A | 1978-10-19 | 1978-10-19 | |
PCT/US1979/000862 WO1980000841A1 (en) | 1978-10-19 | 1979-10-18 | Process for producing oxymorphone |
Publications (1)
Publication Number | Publication Date |
---|---|
DK258280A true DK258280A (da) | 1980-06-17 |
Family
ID=25493512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK258280A DK258280A (da) | 1978-10-19 | 1980-06-17 | Fremgangsmaade til fremstilling af oxymorfon |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS55501025A (da) |
AU (1) | AU5189779A (da) |
BE (1) | BE879494A (da) |
CA (1) | CA1108132A (da) |
CS (1) | CS211364B2 (da) |
DK (1) | DK258280A (da) |
ES (1) | ES485154A1 (da) |
FI (1) | FI793235A (da) |
FR (1) | FR2439201A1 (da) |
GB (1) | GB2049680A (da) |
IL (1) | IL58489A0 (da) |
IT (1) | IT7969032A0 (da) |
NL (1) | NL7920126A (da) |
NO (1) | NO793297L (da) |
SE (1) | SE8004454L (da) |
WO (1) | WO1980000841A1 (da) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4795813A (en) * | 1981-08-17 | 1989-01-03 | The Florida Board Of Regents On Behalf Of The Florida State University | Synthesis of derivatives of codeine and other 3-O-alkylmorphines |
US5668285A (en) * | 1986-10-31 | 1997-09-16 | The United States Of America As Represented By The Department Of Health And Human Services | Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates |
FR2636330B1 (fr) * | 1988-09-13 | 1990-11-30 | Sanofi Sa | Procede de preparation de derives de morphinane |
AU642447B2 (en) * | 1989-10-16 | 1993-10-21 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via N-nor intermediates |
US8329216B2 (en) | 2001-07-06 | 2012-12-11 | Endo Pharmaceuticals Inc. | Oxymorphone controlled release formulations |
BR0205721A (pt) | 2001-07-06 | 2003-09-30 | Endo Pharmaceuticals Inc | Formulações de oximorfona de liberação controlada |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE602007003197D1 (de) | 2006-03-02 | 2009-12-24 | Mallinckrodt Inc | Verfahren zur herstellung von morphinan-6-on-produkten mit geringen konzentrationen von alpha-, beta-ungesättigten ketonverbindungen |
NZ586792A (en) | 2008-01-25 | 2012-09-28 | Gruenenthal Chemie | Tamper resistant controlled release pharmaceutical tablets form having convex and concave surfaces |
RU2508092C2 (ru) | 2008-05-09 | 2014-02-27 | Грюненталь Гмбх | Способ получения твердой лекарственной формы, в частности таблетки для фармацевтического применения, и способ получения прекурсора твердой лекарственной формы, в частности таблетки |
CN102573805A (zh) | 2009-07-22 | 2012-07-11 | 格吕伦塔尔有限公司 | 热熔挤出的控制释放剂型 |
WO2011009604A1 (en) | 2009-07-22 | 2011-01-27 | Grünenthal GmbH | Oxidation-stabilized tamper-resistant dosage form |
RU2607499C2 (ru) | 2010-09-02 | 2017-01-10 | Грюненталь Гмбх | Устойчивая к разрушению лекарственная форма, которая содержит анионный полимер |
PL2611426T3 (pl) | 2010-09-02 | 2014-09-30 | Gruenenthal Gmbh | Postać dawkowania zawierająca nieorganiczne sole, odporna na zgniatanie |
BR112014002022A2 (pt) | 2011-07-29 | 2017-02-21 | Gruenenthal Gmbh | comprimido resistente à violação proporcionando liberação de fármaco imediata |
PT2736497T (pt) | 2011-07-29 | 2017-11-30 | Gruenenthal Gmbh | Comprimido resistente a adulteração proporcionando libertação imediata de fármaco |
EP2819656A1 (en) | 2012-02-28 | 2015-01-07 | Grünenthal GmbH | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
MX362357B (es) | 2012-04-18 | 2019-01-14 | Gruenenthal Gmbh | Forma de dosificacion farmaceutica resistente a la adulteracion y resistente a la liberacion inmediata de la dosis. |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
US10154966B2 (en) | 2013-05-29 | 2018-12-18 | Grünenthal GmbH | Tamper-resistant dosage form containing one or more particles |
EP3003283A1 (en) | 2013-05-29 | 2016-04-13 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
WO2015004245A1 (en) | 2013-07-12 | 2015-01-15 | Grünenthal GmbH | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
CN105934241B (zh) | 2013-11-26 | 2020-06-05 | 格吕伦塔尔有限公司 | 通过低温研磨制备粉末状药物组合物 |
EP3142646A1 (en) | 2014-05-12 | 2017-03-22 | Grünenthal GmbH | Tamper resistant immediate release capsule formulation comprising tapentadol |
EP3148512A1 (en) | 2014-05-26 | 2017-04-05 | Grünenthal GmbH | Multiparticles safeguarded against ethanolic dose-dumping |
MX2017013637A (es) | 2015-04-24 | 2018-03-08 | Gruenenthal Gmbh | Forma de dosificacion resistente a alteraciones con liberacion inmediata y resistencia contra la extraccion por solventes. |
US10842750B2 (en) | 2015-09-10 | 2020-11-24 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
EP3252055B1 (en) | 2016-05-31 | 2018-09-19 | Alcaliber Investigacion Desarrollo e Innovacion SLU | Process for obtaining 3,14-diacetyloxymorphone from oripavine |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3249616A (en) * | 1966-05-03 | Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof | ||
US2806033A (en) * | 1955-08-03 | 1957-09-10 | Lewenstein | Morphine derivative |
US3775414A (en) * | 1972-05-10 | 1973-11-27 | Bristol Myers Co | Process for the preparation of 14-hydroxymorphinan derivatives |
-
1979
- 1979-10-12 NO NO793297A patent/NO793297L/no unknown
- 1979-10-18 IT IT7969032A patent/IT7969032A0/it unknown
- 1979-10-18 CA CA337,908A patent/CA1108132A/en not_active Expired
- 1979-10-18 ES ES485154A patent/ES485154A1/es not_active Expired
- 1979-10-18 FI FI793235A patent/FI793235A/fi not_active Application Discontinuation
- 1979-10-18 IL IL58489A patent/IL58489A0/xx unknown
- 1979-10-18 GB GB8014422A patent/GB2049680A/en not_active Withdrawn
- 1979-10-18 JP JP50190279A patent/JPS55501025A/ja active Pending
- 1979-10-18 NL NL7920126A patent/NL7920126A/nl unknown
- 1979-10-18 WO PCT/US1979/000862 patent/WO1980000841A1/en unknown
- 1979-10-18 AU AU51897/79A patent/AU5189779A/en not_active Abandoned
- 1979-10-18 BE BE0/197710A patent/BE879494A/fr unknown
- 1979-10-18 FR FR7925895A patent/FR2439201A1/fr not_active Withdrawn
- 1979-10-19 CS CS797115A patent/CS211364B2/cs unknown
-
1980
- 1980-06-16 SE SE8004454A patent/SE8004454L/xx not_active Application Discontinuation
- 1980-06-17 DK DK258280A patent/DK258280A/da unknown
Also Published As
Publication number | Publication date |
---|---|
AU5189779A (en) | 1980-04-24 |
GB2049680A (en) | 1980-12-31 |
IT7969032A0 (it) | 1979-10-18 |
WO1980000841A1 (en) | 1980-05-01 |
NL7920126A (nl) | 1980-08-29 |
CS211364B2 (en) | 1982-02-26 |
ES485154A1 (es) | 1980-06-16 |
BE879494A (fr) | 1980-02-15 |
JPS55501025A (da) | 1980-11-27 |
FR2439201A1 (fr) | 1980-05-16 |
SE8004454L (sv) | 1980-06-16 |
IL58489A0 (en) | 1980-01-31 |
FI793235A (fi) | 1980-04-20 |
CA1108132A (en) | 1981-09-01 |
NO793297L (no) | 1980-04-22 |
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